Hepatitis B virus infections transmitted from retarded children to their families during brief home exposure.

Abstract:

:Hepatitis B virus (HBV) infection is endemic among institutionalized retarded patients, who usually have mild, anicteric hepatitis following nonparenteral exposure. We evaluated the risk of HBV infection (as evidenced by serologic studies) among their contacts, including noninstitutional caretakers, during brief home exposure. Caretakers shaved, bathed, and changed diapers for five patients during home visits or foster home placements. Seven of the 14 caretakers, who were exposed for 3-12 months, developed antibodies (anti-HBc and/or anti-HBs). A mother and her daughter's caretaker were found to have asymptomatic acute HBV infection, and the mother developed antibodies to HBs, HBc, and HBe. In a second household, another caretaker became anti-HBs-positive. Only one of nine play contacts and none of seven casual contacts had markers of past or present HBV infection. The study was a unique opportunity to retrospectively and prospectively monitor HBV transmission. Our results show that noninstitutional caretakers deserve the protection of HBV vaccine to diminish the potential for chronic infection and transmission of HBV infection.

authors

McPhillips JC,Collins JC,Spigland I

doi

10.1097/00005176-198401000-00015

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

69-71

issue

1

eissn

0277-2116

issn

1536-4801

journal_volume

3

pub_type

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