Abstract:
:Steady state photolysis and time resolved near infrared luminescence detection were employed to study the reaction kinetics of singlet oxygen with three different lipid-soluble probes incorporated in large unilamellar dioctadecyldimethylammonium chloride (DODAC) vesicles. The probes: 2-(4-(N,N,N-trimethylamine)-butyl)-5-dodecylfuryl bromide (DFTA), 2-(12-(N,N,N-trimethylamine)-dodecyl)-5-hexylfuryl bromide (HFDA) and 2-(1-(N,N,N-trimethylamine)-methyl)-5-methylfuryl iodide (MFMA) are useful in studying both singlet oxygen dynamics and its equilibrium in microcompartmentalized systems because they are actinometers in lipidic microphases. These probes contain a reactive furan ring, which will be located at different depths in the bilayer of DODAC vesicles. In the limit of the approximations, the result indicates an inhomogeneous equilibrium distribution of singlet oxygen across the bilayer. The calculated mean partitioning constant of singlet oxygen equals 2.8 and 8.3 at 20 degrees C and 40 degrees C, respectively, in the order of the previously reported constants for other microorganized systems such as sodium dodecylsulfate and cetyltrimethylammonium halide micelles and water/oil microemulsions.
journal_name
Photochem Photobioljournal_title
Photochemistry and photobiologyauthors
Zanocco AL,Meléndrez M,Günther G,Lemp Edoi
10.1562/2006-08-01-RA-991subject
Has Abstractpub_date
2007-05-01 00:00:00pages
584-91issue
3eissn
0031-8655issn
1751-1097pii
2006-08-01-RA-991journal_volume
83pub_type
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