The relation of blood pressure to stroke prognosis.

abstract：:Patients with variant angina refractory to medical therapy pose a difficult management problem. We report two patients with variant angina who had focal spasm in coronary arteries with fixed obstructions of less than 20% of the luminal diameter. Ischemic episodes were accompanied by malignant ventricular arrhythmias a...

journal_title：Annals of internal medicine

authors： Sussman EJ,Goldberg S,Poll DS,MacVaugh H 3rd,Simson MB,Silber SA,Kastor JA

更新日期：1981-06-01 00:00:00

abstract：:Comprehensive palliative care, as exemplified by many state-of-the-art hospice programs, is the standard of care for the dying. Although palliative care is very effective, physicians, nurses, patients, families, and loved ones regularly face clinically, ethically, legally, and morally challenging decisions throughout ...

journal_title：Annals of internal medicine

authors： Quill TE,Lee BC,Nunn S

更新日期：2000-03-21 00:00:00

abstract：BACKGROUND:The established International Prognostic Index for lymphomas has not included patients with systemic AIDS-related non-Hodgkin lymphoma. OBJECTIVE:To establish the most appropriate prognostic index for use in patients with systemic AIDS-related non-Hodgkin lymphoma. DESIGN:A prospective study involving univ...

journal_title：Annals of internal medicine

authors： Bower M,Gazzard B,Mandalia S,Newsom-Davis T,Thirlwell C,Dhillon T,Young AM,Powles T,Gaya A,Nelson M,Stebbing J

更新日期：2005-08-16 00:00:00

abstract：:The U.S. Preventive Services Task Force (USPSTF) makes recommendations on which preventive services to routinely incorporate into primary care for specific populations. Behavioral counseling interventions are preventive services designed to help persons engage in healthy behaviors and limit unhealthy ones. The USPSTF'...

journal_title：Annals of internal medicine

authors： Curry SJ,Grossman DC,Whitlock EP,Cantu A

更新日期：2014-03-18 00:00:00

abstract：Background:Central line-associated bloodstream infection (CLABSI) remains prevalent in hospitals in the United States. Objective:To evaluate the impact of a multimodal intervention in hospitals with elevated rates of health care-associated infection. Design:Pre-post observational evaluation of a prospective, national...

journal_title：Annals of internal medicine

authors： Patel PK,Greene MT,Jones K,Rolle AJ,Ratz D,Snyder A,Saint S,Chopra V

更新日期：2019-10-01 00:00:00

abstract：DESCRIPTION:Although approximately 85 million units of red blood cells (RBCs) are transfused annually worldwide, transfusion practices vary widely. The AABB (formerly, the American Association of Blood Banks) developed this guideline to provide clinical recommendations about hemoglobin concentration thresholds and othe...

journal_title：Annals of internal medicine

authors： Carson JL,Grossman BJ,Kleinman S,Tinmouth AT,Marques MB,Fung MK,Holcomb JB,Illoh O,Kaplan LJ,Katz LM,Rao SV,Roback JD,Shander A,Tobian AA,Weinstein R,Swinton McLaughlin LG,Djulbegovic B,Clinical Transfusion Medicine Com

更新日期：2012-07-03 00:00:00

abstract：:Internal medicine residencies risk becoming obsolete if they are not adjusted to changing patterns of medical practice. Declining length of hospital stay, increased intensity of hospital care, movement of critical management decisions to outpatient settings, increased proportions of admissions for specific diagnostic ...

journal_title：Annals of internal medicine

authors： Schroeder SA,Showstack JA,Gerbert B

更新日期：1986-04-01 00:00:00

abstract：PURPOSE:Chemoprevention offers promise as a strategy for reducing morbidity and mortality from breast cancer in women. This review examined the evidence for the effectiveness of chemoprevention in women without a history of breast cancer. DATA SOURCES:MEDLINE (1966 to December 2001). STUDY SELECTION:English-language,...

journal_title：Annals of internal medicine

authors： Kinsinger LS,Harris R,Woolf SH,Sox HC,Lohr KN

更新日期：2002-07-02 00:00:00

abstract：BACKGROUND:Because clinical diagnosis is inaccurate, objective testing is usually considered necessary when patients present with suspected deep venous thrombosis (DVT). OBJECTIVE:To determine whether a negative result on a quantitative latex D dimer assay eliminates the need for further investigation in patients with...

journal_title：Annals of internal medicine

authors： Bates SM,Kearon C,Crowther M,Linkins L,O'Donnell M,Douketis J,Lee AY,Weitz JI,Johnston M,Ginsberg JS

更新日期：2003-05-20 00:00:00

abstract：OBJECTIVE:To define the temporal characteristics of cocaine-induced coronary vasoconstriction in humans and to assess the relation between cocaine-induced coronary vasoconstriction and the blood concentration of cocaine and its main metabolites. DESIGN:Randomized, double-blind, controlled clinical trial. SETTING:Card...

journal_title：Annals of internal medicine

authors： Brogan WC 3rd,Lange RA,Glamann DB,Hillis LD

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Increased prevalence of adolescent obesity requires effective treatment options beyond behavior therapy. OBJECTIVE:To see whether sibutramine reduced weight more than placebo in obese adolescents who were receiving a behavior therapy program. DESIGN:12-month, 3:1 randomized, double-blind trial conducted fr...

journal_title：Annals of internal medicine

authors： Berkowitz RI,Fujioka K,Daniels SR,Hoppin AG,Owen S,Perry AC,Sothern MS,Renz CL,Pirner MA,Walch JK,Jasinsky O,Hewkin AC,Blakesley VA,Sibutramine Adolescent Study Group.

更新日期：2006-07-18 00:00:00

abstract：:Sudden cardiac death remains a leading cause of death in the United States, accounting for more than 350,000 deaths each year, and the survival rate of victims remains low. Most survivors face a significant risk for recurrence. The typical substrate is chronic--abnormal myocardium with fibrosis (often from previous my...

journal_title：Annals of internal medicine

authors： Akhtar M,Garan H,Lehmann MH,Troup PJ

更新日期：1991-03-15 00:00:00

abstract：BACKGROUND:Plasma levels of leptin, the recently discovered satiety hormone, are associated with adiposity in humans. OBJECTIVE:To determine whether genetic factors or body fat distribution affect the association between leptin levels and obesity. PARTICIPANTS:23 healthy identical twin pairs (9 male pairs and 14 fema...

journal_title：Annals of internal medicine

authors： Rönnemaa T,Karonen SL,Rissanen A,Koskenvuo M,Koivisto VA

更新日期：1997-01-01 00:00:00

abstract：DESCRIPTION:Update of the 2005 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for abdominal aortic aneurysm (AAA). METHODS:The USPSTF commissioned a systematic review that assessed the evidence on the benefits and harms of screening for AAA and strategies for managing small (3.0 to 5.4 cm) sc...

journal_title：Annals of internal medicine

authors： LeFevre ML,U.S. Preventive Services Task Force.

更新日期：2014-08-19 00:00:00

abstract：BACKGROUND:A sensitive and acceptable screening regimen for women at high risk for breast cancer is essential. Contrast-enhanced magnetic resonance imaging (MRI) of the breast is highly sensitive for diagnosis of breast cancer but has variable specificity. PURPOSE:To summarize the sensitivity, specificity, likelihood ...

journal_title：Annals of internal medicine

authors： Warner E,Messersmith H,Causer P,Eisen A,Shumak R,Plewes D

更新日期：2008-05-06 00:00:00

abstract：:Chronic lymphocytic leukemia developed in four of five siblings, whose father succumbed to the same disease. The pattern of immune deficiency in the leukemic siblings resembled that found in nonfamilial cases of chronic lymphocytic leukemia, and was correlated with the severity of clinical involvement. In three siblin...

journal_title：Annals of internal medicine

authors： Blattner WA,Strober W,Muchmore AV,Blaese RM,Broder S,Fraumeni JF Jr

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:Prospective data defining the clinical course in idiopathic pulmonary fibrosis (IPF) are sparse. OBJECTIVE:To analyze the clinical course of patients with mild to moderate IPF. DESIGN:Analysis of data from the placebo group of a randomized, controlled trial evaluating interferon-gamma1b. SETTING:Academic ...

journal_title：Annals of internal medicine

authors： Martinez FJ,Safrin S,Weycker D,Starko KM,Bradford WZ,King TE Jr,Flaherty KR,Schwartz DA,Noble PW,Raghu G,Brown KK,IPF Study Group.

更新日期：2005-06-21 00:00:00

abstract：:The training of physicians for the delivery of primary care is becoming a national priority. The period of residency training is viewed by many as the focal point for educational change to meet this demand. The Residency Program in Social Medicine at Montefiore Hospital and Medical Center was begun in 1970 and offers ...

journal_title：Annals of internal medicine

authors： Boufford JI

更新日期：1977-09-01 00:00:00

abstract：:We evaluated bone disease in eight white men between the ages of 49 and 61 years who had been abusing alcohol for at least 10 years. The mean density of vertebral cancellous bone was 58% of normal, whereas the mean density of appendicular cortical bone was 90% of normal. Marked reduction in active bone resorption and ...

journal_title：Annals of internal medicine

authors： Bikle DD,Genant HK,Cann C,Recker RR,Halloran BP,Strewler GJ

更新日期：1985-07-01 00:00:00

abstract：:Type 2 diabetes mellitus is a metabolic disease of carbohydrate metabolism. However, it should also be considered a vascular disease because diabetic patients have a strong predilection for atherosclerosis. With the increasing prevalence and earlier age at onset of diabetes, the projected effect of diabetes on cardiov...

journal_title：Annals of internal medicine

authors： Hurst RT,Lee RW

更新日期：2003-11-18 00:00:00

abstract：OBJECTIVE:To compare generalists' and cardiologists' estimates of baseline cardiovascular risk and the outcomes of preventive therapy. DESIGN:Cross-sectional mail survey using written case simulations of typical patients from primary prevention trials for hypercholesterolemia and isolated systolic hypertension, and te...

journal_title：Annals of internal medicine

authors： Friedmann PD,Brett AS,Mayo-Smith MF

更新日期：1996-02-15 00:00:00

abstract：BACKGROUND:Thymectomy is standard therapy fornonthymomatousmyasthenia gravis despite the absence of randomized clinical trials (1). Myasthenia gravis is uncommonly reported in monozygous twins; disease concordance occurs in approximately one third of such identical twin pairs; and treatment for myasthenia gravis, when ...

journal_title：Annals of internal medicine

authors： Riggs KR,Gutmann L,Riggs JE

更新日期：2011-10-04 00:00:00

abstract：BACKGROUND:The number of very elderly persons who are candidates for implantation of a permanent pacemaker is increasing, but the effect of cardiac pacing on long-term survival and functional variables has not been determined. OBJECTIVE:To determine long-term survival after implantation of a permanent pacemaker in oct...

journal_title：Annals of internal medicine

authors： Shen WK,Hayes DL,Hammill SC,Bailey KR,Ballard DJ,Gersh BJ

更新日期：1996-09-15 00:00:00

abstract：Background:Iron chelation therapy (ICT) in patients with lower-risk myelodysplastic syndromes (MDS) has not been evaluated in randomized studies. Objective:To evaluate event-free survival (EFS) and safety of ICT in iron-overloaded patients with low- or intermediate-1-risk MDS. Design:Multicenter, randomized, double-b...

journal_title：Annals of internal medicine

authors： Angelucci E,Li J,Greenberg P,Wu D,Hou M,Montano Figueroa EH,Rodriguez MG,Dong X,Ghosh J,Izquierdo M,Garcia-Manero G,TELESTO Study Investigators.

更新日期：2020-04-21 00:00:00

abstract：:Effective health care is a core determinant of successful aging, and medications are one of the most important therapeutic tools of health care providers. Most older adults use at least one prescription drug. Costs for these drugs are a substantial out-of-pocket expense for Medicare beneficiaries, and low-income older...

journal_title：Annals of internal medicine

authors： Murray MD,Callahan CM

更新日期：2003-09-02 00:00:00

abstract：:An investigation of patient care in four hospitals compared levels of resource use between 1964 and 1974 for patients with a primary diagnosis of pneumonia. Results showed a decreased length of stay in all hospitals. Unique patterns of increases and decreases existed in each hospital for the changing use of diagnostic...

journal_title：Annals of internal medicine

authors： Sheeley DR,Sherman H

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Markers are needed for assessing response to antiretroviral therapy over time. The CD4+ lymphocyte count is one such surrogate, but it is relatively weak. OBJECTIVE:To assess the association of changes in plasma human immunodeficiency virus (HIV) RNA level and CD4+ lymphocyte count with progression to the a...

journal_title：Annals of internal medicine

authors： O'Brien WA,Hartigan PM,Daar ES,Simberkoff MS,Hamilton JD

更新日期：1997-06-15 00:00:00

abstract：BACKGROUND:AL amyloidosis is a fatal disease resulting from tissue deposition of amyloid fibrils derived from monoclonal immunoglobulin light chains. Treatment with oral chemotherapy is minimally effective. OBJECTIVE:To test survival and organ response in a large sample of patients treated with high-dose intravenous m...

journal_title：Annals of internal medicine

authors： Skinner M,Sanchorawala V,Seldin DC,Dember LM,Falk RH,Berk JL,Anderson JJ,O'Hara C,Finn KT,Libbey CA,Wiesman J,Quillen K,Swan N,Wright DG

更新日期：2004-01-20 00:00:00

abstract：OBJECTIVE:To describe 13 infections caused by Mycobacterium haemophilum. DESIGN:Identification of patients by microbiologic record review, followed by medical record review and a case-control study. SETTING:Seven metropolitan hospitals in New York. PATIENTS:All patients with M. haemophilum infections diagnosed betwe...

journal_title：Annals of internal medicine

authors： Straus WL,Ostroff SM,Jernigan DB,Kiehn TE,Sordillo EM,Armstrong D,Boone N,Schneider N,Kilburn JO,Silcox VA,LaBombardi V,Good RC

更新日期：1994-01-15 00:00:00

abstract：:A case of a patient with metastatic cancer raises the issues of patient refusal of treatment, euthanasia, and unintended side effects of therapy. For each management dilemma, there are relevant ethical and legal considerations, justifications, and conclusions. In addition, psychological and social influences on the de...

journal_title：Annals of internal medicine

authors： Lo B,Jonsen AR

更新日期：1980-01-01 00:00:00