Abstract:
OBJECTIVES:Trichophyton tonsurans is the single most common cause of pediatric dermatophytoses in North America and is observed with increasing frequency in other countries. This investigation was designed to gain insight into the natural course of T. tonsurans infection. PATIENTS AND METHODS:This 2-year prospective, longitudinal study evaluated all preschool-aged children attending a single child care center. Scalp cultures were collected monthly from each child in attendance, and the presence of disease symptoms recorded at each visit. Dermatophyte genotype was assigned based on the combination of stable sequence variations (2 length variants, 8 single-nucleotide polymorphisms, a 10-base pair insertion, a 14-base pair deletion) present in 2 gene loci. RESULTS:A total of 3541 scalp cultures were collected from 446 children during 24 months. Twenty-two percent to 51% of scalp cultures per month were positive, contributing 1390 fungal cultures of which 1048 were typeable. Among children with multiple typeable isolates, 51% exclusively carried the same strain, 37% demonstrated a single predominant strain with secondary strains transiently acquired, and 12% harbored a different strain of T. tonsurans with each typeable culture. The probability that the same strain persisted in subsequent months was 0.898 and unlikely to have arisen by chance. Rates of symptomatic disease were significantly different between exclusive, predominant, and transient carriers of T. tonsurans. CONCLUSIONS:In contrast to dermatophyte infections in older individuals, where symptomatic disease seems to be a consequence of pathogen acquisition and carriers can be traced to an index case, in this preschool-aged population infection was endemic, and symptomatic disease seemed to represent activation of a single strain that persisted on the scalp.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Abdel-Rahman SM,Simon S,Wright KJ,Ndjountche L,Gaedigk Adoi
10.1542/peds.2006-2065subject
Has Abstractpub_date
2006-12-01 00:00:00pages
2365-73issue
6eissn
0031-4005issn
1098-4275pii
118/6/2365journal_volume
118pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract::Influenza-associated encephalitis and encephalopathy (IAE) is a severe complication of influenza infection with high morbidity and mortality. We present the case of a patient with IL-10RA mutation who developed encephalopathy after influenza infection. A 10-day-old boy developed recurrent fever and anal fistula. Growt...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-3548
更新日期:2018-06-01 00:00:00
abstract::To assess the relative competence of pediatricians and general practitioners in managing febrile illnesses in childhood, a prospective study was undertaken of 259 children less than 10 years of age seen consecutively at the emergency room of a children's hospital and a general hospital. Both groups of patients were si...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1982-10-01 00:00:00
abstract:BACKGROUND:Childhood asthma prevalence doubled from 1980 to 1995 and then increased more slowly from 2001 to 2010. During this second period, racial disparities increased. More recent trends remain to be described. METHODS:We analyzed current asthma prevalence using 2001-2013 National Health Interview Survey data for ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-2354
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To investigate the efficacy of a cognitive-behavioral group intervention for children with chronic illnesses and to test the effect of an added parent component. METHODS:Children (n = 194) and their parents participated in a multicenter randomized clinical trial comparing a child-only intervention and a pare...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2012-2222
更新日期:2013-04-01 00:00:00
abstract::High-deductible health plans (HDHPs) are insurance policies with higher deductibles than conventional plans. The Medicare Prescription Drug Improvement and Modernization Act of 2003 linked many HDHPs with tax-advantaged spending accounts. The 2010 Patient Protection and Affordable Care Act continues to provide for HDH...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-0555
更新日期:2014-05-01 00:00:00
abstract::In this cross-sectional study, the vision-screening process is described for 8417 children aged 3 to 5 seen for health supervision in a group of 102 pediatric practices in 23 states and Puerto Rico. Three hundred forty children who failed screening (63% of those who failed) were followed up 2 months after initial scre...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract::Informed consent should be seen as an essential part of health care practice; parental permission and childhood assent is an active process that engages patients, both adults and children, in their health care. Pediatric practice is unique in that developmental maturation allows, over time, for increasing inclusion of...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-1485
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to use nationwide registries to examine the health of children up to 4 years of age who were born as a result of in vitro fertilization. METHODS:Children born after in vitro fertilization (N = 4559) from 1996 to 1999 were monitored until 2003. Two control groups were selected fr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-0735
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:Adolescence is an important period of risk for the development of lifelong smoking behaviors. Compelling, although inconsistent, evidence suggests a relationship between parental smoking and the risk of smoking initiation during adolescence. This study investigates unresolved issues concerning the strength an...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-2251
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Children with sickle cell anemia (SCA) are at increased risk for invasive pneumococcal disease; antibiotic prophylaxis significantly reduces this risk. We calculated the proportion of children with SCA who received ≥300 days of antibiotic prophylaxis and identified predictors of such receipt. METHODS:Childr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-2182
更新日期:2018-03-01 00:00:00
abstract::Ankyloglossia (tongue tie) is a well-recognized cause of breastfeeding difficulties and, if untreated, can cause maternal nipple pain and trauma, ineffective feeding, and poor infant weight gain. In some cases, this condition will result in a downregulation of the maternal milk supply. Milk-production measurements (24...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-2651
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Controversy exists regarding the most appropriate acute management of central venous catheters (CVCs) in neonates with candidemia, with up to two thirds of neonatologists preferring to attempt antifungal therapy without removing CVCs. OBJECTIVE:To determine whether CVCs should be removed as soon as candidem...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.106.5.e63
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Thermoregulation is impaired during desynchronized sleep in animals and in adults. This can lead to a conflict between homeothermy and sleep in nonthermoneutral conditions. This study aimed to analyze thermoregulation during sleep, especially during desynchronized sleep (active sleep, AS) and t...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVE:To identify vaccination policies and beliefs associated with practice immunization rates (PIR) among office-based pediatricians. METHODS:Primary care pediatricians recruited from the Pediatric Research in Office Settings (PROS) network of the American Academy of Pediatrics or the Pediatric Section of the Nat...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.109.2.294
更新日期:2002-02-01 00:00:00
abstract::We report on successful early eculizumab administration to treat acute antibody-mediated rejection (ABMR) in a highly sensitized kidney transplant recipient. The recipient is a 7-year-old boy who received, 6 months after a desensitization protocol with monthly intravenous immunoglobulin infusion, a second kidney trans...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-2275
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to determine parent and provider knowledge and awareness of newborn screening; to gather opinions from parents, providers, and newborn screening professionals about the content and timing of newborn screening education; and to use consensus data to formulate recommendations and to...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-2633M
更新日期:2006-05-01 00:00:00
abstract::Building a strong foundation for healthy development in the early years of life is a prerequisite for individual well-being, economic productivity, and harmonious societies around the world. Growing scientific evidence also demonstrates that social and physical environments that threaten human development (because of ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-0366
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To report on the development of the Questionnaire for Identifying Children with Chronic Conditions (QuICCC). This new instrument identifies children and adolescents who have chronic health conditions based on the noncategorical conceptual framework outlined in our earlier work. It uses the consequences of con...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.99.4.513
更新日期:1997-04-01 00:00:00
abstract:BACKGROUND:The Parent Report of Children's Abilities-Revised (PARCA-R) is a questionnaire for assessing cognitive and language development in very preterm infants. Given the increased risk of developmental delay in infants born late and moderately preterm (LMPT; 32-36 weeks), this study aimed to validate this questionn...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-0266
更新日期:2014-07-01 00:00:00
abstract::Venipuncture and intravenous cannulation are among the most common and widespread medical procedures performed on children today. Therefore, effective treatment of venous access pain can benefit from an integrated systems approach that enlists multiple players in the health care system. By using case studies that anal...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2008-1055i
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:To examine whether parenting styles or practices were associated with children's television (TV) viewing. METHODS:A total of 431 parent-child dyads (10- to 11-year-old children) from Bristol, United Kingdom, were included. Child and parent TV viewing were self-reported and categorized as <2, 2 to 4, or >4 ho...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-3664
更新日期:2011-09-01 00:00:00
abstract::Data for this article, as in previous reports, are drawn principally from the Monthly Vital Statistics Report, published by the National Center for Health Statistics. The international data come from the Demographic Yearbook and the quarterly Population and Vital Statistics Report, both published by the Statistical Of...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract:OBJECTIVE:To assess whether weight-related teasing predicts the development of binge eating, unhealthy weight control behaviors, and frequent dieting among male and female adolescents. METHODS:A prospective study was conducted with an ethnically and socioeconomically diverse sample of 2516 adolescents who completed su...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-1242
更新日期:2006-02-01 00:00:00
abstract::Secondary hyperlipidemia is a common laboratory finding in children with nephrotic syndrome, diabetes mellitus, and hypothyroidism. However, clinical signs of hyperlipidemia are extremely rare in childhood. We report on an 11-year-old girl who presented with a disseminated yellow papulomatous rash on the lower limbs a...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.5.e96
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVE:This study validates the Modified Checklist for Autism in Toddlers, Revised with Follow-up (M-CHAT-R/F), a screening tool for low-risk toddlers, and demonstrates improved utility compared with the original M-CHAT. METHODS:Toddlers (N = 16,071) were screened during 18- and 24-month well-child care visits in m...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-1813
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Medication use may be a target for quality improvement, cost containment, and research. We aimed to identify medication classes associated with the highest expenditures among pediatric Medicaid enrollees and to characterize the demographic, clinical, and health service use of children prescrib...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-1095
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVES:To examine associations of the timing of complementary feeding (CF) introduction with adiposity throughout childhood. METHODS:We studied 1013 children from Project Viva. Our exposure was CF introduction, categorized as <4 months (19%), 4 to <6 months (68%; reference group), and ≥6 months of age (14%). Our o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-1320
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:An evaluation of the opportunity to introduce fiber in the diet of weaning infants. METHODS:A descriptive review of the literature to assess the role of fiber in the following dietary interventions: (1) definition of the nutrient amounts that meet the weaning infant's physiologic needs; (2) modulation of dig...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVES:To determine the frequency of physician-documented sexual histories in female adolescents who presented to an emergency department (ED) with symptoms suggestive of a sexually transmitted infection (STI). Our secondary objectives were to determine if physician-documented sexual history is associated with incr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-1775
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To investigate racial/ethnic differences in acute asthma among children who present to the emergency department (ED). METHOD:We analyzed data from 2 prospective cohort studies performed during 1997-1998 as part of the Multicenter Airway Research Collaboration. Using a standardized protocol, researchers at 40...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.111.5.e615
更新日期:2003-05-01 00:00:00