Abstract：
:Biochemical alterations in guinea pig lungs caused by hematite dust were followed at 150 days after intratracheal administration of the dust. In vivo dust exposure caused a significant increase in mitochondrial protein content and cytochrome c oxidase activity whereas diaphorase activity remained unaltered. Mitochondria from the exposed animals were apparently in a swollen state and their contraction profile upon the addition of ATP reflected permeability changes. However, in vitro dust caused no significant alterations. Significant increases in glycogen content along with an insignificant decrease in glycogen phosphorylase activity were also observed in hematite-treated guinea pig lungs. Decrease in drug-metabolizing enzymes such as aniline hydroxylase and tyrosine aminotransferase activities were also evident in the postmitochondrial fraction of the siderotic lungs. [3H]Leucine-incorporation studies showed increased protein synthesis in the postmitochondrial fraction. Increase in protein synthesis in mitochondria was only marginal whereas in whole homogenate it decreased considerably. Experiments employing dust tagged with radioactive iron indicated the rapid mobilization of iron from lung and its distribution to various organs. The presence of iron-binding protein was confirmed by employing Sephadex gel-filtration techniques.
journal_name
Environ Resjournal_title
Environmental researchauthors
Das B,Khatoon N,Srivastava RC,Viswanathan PN,Rahman Qdoi
10.1016/0013-9351(83)90119-6subject
Has Abstractpub_date
1983-12-01 00:00:00pages
372-81issue
2eissn
0013-9351issn
1096-0953pii
0013-9351(83)90119-6journal_volume
32pub_type
杂志文章abstract：OBJECTIVES:To evaluate the effect of short-term exposure to air pollutants on inflammation-sensitive biomarkers in apparently healthy individuals. METHODS:We enrolled all participants from The Tel-Aviv Sourasky Medical Center inflammation survey held between 2003 and 2006, excluding participants with an acute or chron...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2007.08.006
更新日期：2008-01-01 00:00:00
abstract：:The effects of cadmium on the immune system have been extensively studied, although relatively little is known about the nature of the interaction between cadmium and lymphocytes. We describe studies that examine the uptake and subcellular distribution of cadmium in resting and mitogen-activated mouse splenic lymphocy...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(89)80071-4
更新日期：1989-08-01 00:00:00
abstract：:Elevated exposure to arsenic disproportionately affects populations relying on private well water in the United States (US). This includes many American Indian (AI) communities where naturally occurring arsenic is often above 10 µg/L, the current US Environmental Protection Agency safety standard. The Strong Heart Wat...
journal_title：Environmental research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.envres.2018.09.016
更新日期：2019-01-01 00:00:00
abstract：:Despite the behaviors of ZnO nanoparticles (ZnO NPs) in wastewater treatment processes have been widely explored, the impacts of ZnO NPs on the activated sludge's flocculation and sedimentation performances for solid-liquid separation have rarely been involved yet. In this study, ZnO NPs were observed to exert a dose-...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110256
更新日期：2021-01-01 00:00:00
abstract：:Human exposure to poly- and perfluoroalkyl substances (PFASs) is widespread and has received considerable attention in recent years due to their link with adverse health outcomes, including bone health. Nevertheless, no earlier studies have reported serum PFAS concentrations, and their association with incident osteop...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109676
更新日期：2020-08-01 00:00:00
abstract：:The purpose of this work is to assess the effect of ozone, a reactive product of environmental photochemical oxidation, on lymphocytes of the lung. We exposed male Fischer rats to ozone at a concentration of 0.5 ppm for 20 hr/day for 1-14 days. Animals were treated with radioactive thymidine and were sacrificed at Day...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(05)80089-1
更新日期：1990-04-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(05)80240-3
更新日期：1992-10-01 00:00:00
abstract：:The effect of exposure to lead on the longitudinal development of the femur and of its cartilage growth plate was studied in rats. A group of forty-five 50-day-old female Wistar rats was divided into a control group of 20 rats and an experimental group of 25 rats fed a diet supplemented with 17 mg of lead acetate per ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1997.3760
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Hexavalent chromium (Cr(6+)) has long been recognized as an inhalation carcinogen. Useful data on its carcinogenicity by ingestion have been slower to develop. The 2008 NTP chronic bioassay of sodium dichromate dihydrate in drinking water found clear evidence of carcinogenicity in rodents and allows a genera...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2010.08.002
更新日期：2010-11-01 00:00:00
abstract：:On May 24-25, 2005 in Ann Arbor, Michigan, the US Environmental Protection Agency, the National Institute of Environmental Health Sciences, and the University of Michigan sponsored a technical workshop on the topic of connecting social and environmental factors to measure and track environmental health disparities. Th...
journal_title：Environmental research
pub_type：
doi：10.1016/j.envres.2005.11.001
更新日期：2006-10-01 00:00:00
abstract：BACKGROUND:Exposure to heavy metals may increase risk of kidney disease, but most studies have examined individual metals or two-way interactions. There is increasing recognition of the importance of studying exposure to metal mixtures and health outcomes. OBJECTIVES:We used Bayesian kernel machine regression (BKMR) t...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110126
更新日期：2020-12-01 00:00:00
abstract：:Particulate matter (PM) composition has a key role in a wide range of health outcomes, such as asthma, chronic obstructive pulmonary disease, lung cancer, cardiovascular disease, and death, among others. Montcada i Reixac, a municipality located in the Barcelona metropolitan area (Catalonia, Spain), for its location a...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.04.010
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Long-term exposure to ambient fine particulate matter (≤ 2.5 μg/m3 in aerodynamic diameter; PM2.5) is significantly associated with increased risk of premature mortality. Our goal was to provide an updated meta-analysis of all-cause and cause-specific mortality associated with exposure to PM2.5 and to better...
journal_title：Environmental research
pub_type： 杂志文章,meta分析
doi：10.1016/j.envres.2018.06.021
更新日期：2018-10-01 00:00:00
abstract：:An attempt has been made to study the biochemical properties of lung alkaline phosphatase so that it may serve as a model for measuring the toxicity of air pollutants, especially metals. Lung was shown to be a better source of this enzyme in comparison to other organs in rats. The optimum pH, metal requirements, subst...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(87)80053-1
更新日期：1987-06-01 00:00:00
abstract：OBJECTIVE:Gut microorganisms contribute to the metabolism of environmental toxicants, including methylmercury (MeHg). Our main objective was to investigate whether associations between biomarkers for prenatal MeHg exposure and maternal gut microbiota differed between early and late gestation. METHODS:Maternal blood an...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.01.014
更新日期：2019-05-01 00:00:00
abstract：BACKGROUND:Previous studies have reported numerous environmental factors for atopic dermatitis (AD), such as allergens and chemical stimulants. However, few studies have addressed the relationship between ambient air pollution and AD at a population level. OBJECTIVE:To evaluate the effect of air pollutants on medical ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110153
更新日期：2020-09-11 00:00:00
abstract：:Human biomonitoring data provide evidence to exposure of environmental chemicals. Physiologically based pharmacokinetic (PBPK) modelling together with an adequate exposure scenario allows to transpose measured concentrations of chemicals or their metabolites into exposure levels, as daily intakes. In France, high leve...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110281
更新日期：2021-01-01 00:00:00
abstract：:Children are especially vulnerable to adverse effects of multiple metals exposure. The aim of this study was to assess some metals concentrations such as lead (Pb), arsenic (As), chromium (Cr), manganese (Mn) and iron (Fe) in whole blood, serum, hair and drinking water samples using inductively coupled plasma-mass spe...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.10.003
更新日期：2015-01-01 00:00:00
abstract：:Exposure to PM10 is associated with cardiovascular effects. We evaluated the effects of PM10 on E-Selectin expression and monocytic cell adhesion in human umbilical vein endothelial cells (HUVECs). HUVEC were exposed to PM10 (5-40 microg/cm2) for 6 h, following which surface E-Selectin expression was detected by fluor...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2006.05.004
更新日期：2007-02-01 00:00:00
abstract：:Lactating female members and spouses of male members of the New York State Angler Cohort who agreed to provide breast milk samples were the subjects of this study. Questionnaires were provided to participants focusing on Lake Ontario fish consumption, reproductive history, and lactation history. Milk samples were anal...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1998.3939
更新日期：1999-02-01 00:00:00
abstract：:The intake of food cadmium (Cd) in microg/day over time can increase the body burden of this element. Some human populations that consume subsistence rice-based diets low in calcium (Ca), iron (Fe), and zinc (Zn) are more susceptible to Cd poisoning than populations that consume more nutritious diets. This study deter...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.2000.4236
更新日期：2001-03-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.08.020
更新日期：2017-11-01 00:00:00
abstract：:The use of Vibrio fischeri as luminescence bacteria is particularly effective in evaluating contaminated sediment. In this study, the ecotoxicity of five core sediments from the Bay of Santander, northern Spain, utilising V. fischeri as marine bacterium, was carried out. Different toxicity assay procedures were applie...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2007.05.009
更新日期：2008-03-01 00:00:00
abstract：BACKGROUND:Epidemiological evidence regarding the relationship between maternal secondhand smoke (SHS) exposure during pregnancy and postnatal SHS exposure and childhood behavioral problems is scarce. OBJECTIVE:The present prebirth cohort study investigated the association between perinatal smoking exposure and behavi...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.08.010
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Exposure to far-field radiofrequency electromagnetic fields (RF-EMF) has raised public concerns in recent decades. However, it is not known if individuals' perception towards the health risks of RF-EMF is dependent on their knowledge of the objectively measured personal RF-EMF exposure levels. OBJECTIVES:Th...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.12.058
更新日期：2019-03-01 00:00:00
abstract：:Fullerenes are carbon nanomaterials that have awaken a strong interest due to their adsorption properties and potential applications in many fields. However, there are some gaps of information about their effects and bioconcentration potential in the aquatic biota. In the present work, freshwater biofilms and snails (...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108715
更新日期：2020-01-01 00:00:00
abstract：:Lead exposure during pregnancy remains a public health problem with potential lifelong impacts on children's growth and development. Mexico is unique in that stunting and obesity are both major public health concerns in children. This situation might be exacerbated by lead exposure which remains more common in Mexico ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.10.014
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:The COVID-19 pandemic has profoundly changed people's ability to recreate in public green spaces, which is likely to exacerbate the psychological impacts of the pandemic. In the current study, we seek to understand whether greenery can support mental health even with insufficient outdoor exposure in times of...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110420
更新日期：2020-11-04 00:00:00
abstract：:There is mounting evidence that maternal exposure to ambient air pollution during pregnancy is associated with adverse birth outcomes. We examined birth weight and small for gestational age (SGA <10th percentile for age and gender) among 26,617 singleton full-term births in Brisbane, Australia (July 2000-June 2003), i...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2006.06.010
更新日期：2007-03-01 00:00:00
abstract：:Heat waves are considered to be increasing in frequency and intensity whereas they comprise a significant weather-related cause of deaths in several countries. Two heat waves occurred in Greece in summer 2007. These severe heat waves are assessed by analyzing the prevailing synoptic conditions, evaluating human therma...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2009.12.002
更新日期：2010-02-01 00:00:00
