Abstract：
:A total of 165 out of 2636 adults aged 60 years or older (6.3 per cent) in Rancho Bernardo, California, had isolated systolic hypertension with a systolic blood pressure greater than or equal to 160 mmHg and a diastolic blood pressure less than 90 mmHg when studied in 1972-1974. A 6.4-year follow-up of this cohort showed isolated systolic hypertension to be as important a risk factor for all-cause mortality as other types of hypertension in both men and women (adjusted relative risk = 1.5, p greater than 0.10). After adjustment for age and other covariates, male but not female subjects with isolated systolic hypertension experienced an excess risk of death from stroke (relative risk = 4.0, p less than 0.10), a relative risk exceeding that seen in men with treated hypertension. Isolated systolic hypertension was unassociated with an excess risk of fatal ischemic heart disease in subjects of either sex in this population. The excess risk of death and stroke is consistent with results published elsewhere, and supports the concept that isolated systolic hypertension is not a benign condition of the elderly. The efficacy and safety of therapeutic intervention in older adults with isolated systolic hypertension remain to be determined.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Garland C,Barrett-Connor E,Suarez L,Criqui MHdoi
10.1093/oxfordjournals.aje.a113644subject
Has Abstractpub_date
1983-09-01 00:00:00pages
365-76issue
3eissn
0002-9262issn
1476-6256journal_volume
118pub_type
杂志文章abstract：:The purpose of this study was to examine the effect of characteristics of social networks and support on depressive symptoms in the elderly. The subjects were 1,962 noninstitutionalized persons 65 years and older from the New Haven Establishment of Populations for Epidemiologic Study of the Elderly in 1982, who were a...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116297
更新日期：1992-02-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2018-03-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwh187
更新日期：2004-07-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2012-10-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009128
更新日期：1997-03-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112965
更新日期：1980-07-01 00:00:00
abstract：:Daily temperatures and snowfall were related to coronary and stroke deaths in selected standard metropolitan statistical areas for the 5-year period 1962-1966. Typically an inverse approximately linear pattern of coronary heart disease (CHD) and of stroke mortality with temperature was seen over the greater part of th...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112261
更新日期：1976-06-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/153.12.1159
更新日期：2001-06-15 00:00:00
abstract：:Parasitologic, serologic, and epidemiologic studies were done during 1967 in Calion, Arkansas (population 544). Infection with Entamoeba histolytica was found to be endemic but was segregated along racial lines. Twenty-two (9.9%) black compared with only one (0.6%) white had E. histolytica demonstrated in one stool ex...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112279
更新日期：1976-07-01 00:00:00
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pub_type： 杂志文章
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更新日期：2007-08-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/155.9.783
更新日期：2002-05-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwaa176
更新日期：2020-09-05 00:00:00
abstract：:A cohort of 888 rural, nonaboriginal persons with non-insulin-dependent diabetes mellitus identified in Western Australia through surveys in 1978-1982 were followed for death until the end of 1986. A total of 257 deaths were observed. Excess mortality in this cohort as compared with the general Australian population w...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116343
更新日期：1992-03-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115425
更新日期：1989-11-01 00:00:00
abstract：:The authors abstracted a sample of 7,536 hospital medical records to validate the accuracy of the coding of obstetric information on 1) birth certificates, 2) a statewide computerized hospital discharge abstract data system, and 3) a linked file merging birth certificates and the hospital abstract data for Washington ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116834
更新日期：1993-07-15 00:00:00
abstract：:In the Nepal Blindness Survey, 39,887 people in 105 sites were examined by 10 ophthalmologists from Nepal and four other countries during 1981. Ophthalmic protocols were pretested on approximately 3000 subjects; however, interobserver variability was inevitable. To quantify the amount of variability and assess the rel...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113633
更新日期：1983-08-01 00:00:00
abstract：:In 2018, the Society for Epidemiologic Research and its partner journal, the American Journal of Epidemiology, assembled a working group to develop a set of papers devoted to the "future of epidemiology." These 14 papers covered a wide range of topic areas and perspectives, from thoughts on our profession, teaching, a...
journal_title：American journal of epidemiology
pub_type： 社论
doi：10.1093/aje/kwz045
更新日期：2019-05-01 00:00:00
abstract：:The relative contribution of menopause to the age-related increase in serum total cholesterol concentration in women is not exactly known. Cross-sectional studies suggest a considerable contribution of menopause, whereas in short-term longitudinal studies, only a small increase was observed around menopause. In a 10-y...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116686
更新日期：1993-02-15 00:00:00
abstract：:A new viral agent, isolated from the serum of an infectious hepatitis patient and designated as Agent II-B, was extensively studied in in vitro and in vivo systems. Agent II-B multiplied well in primary and serial animal cell cultures and in embryonated hen's eggs. Quantal and quantitative infectivity assays were perf...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112715
更新日期：1979-05-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009523
更新日期：1998-04-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117619
更新日期：1995-07-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117283
更新日期：1994-09-15 00:00:00
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pub_type： 杂志文章
doi：10.1093/aje/kwx159
更新日期：2017-10-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwq311
更新日期：2011-01-01 00:00:00
abstract：:Mammographic percent density, the proportion of fibroglandular tissue in the breast, is a strong risk factor for breast cancer, but its determinants in young women are unknown. We examined associations of magnetic resonance imaging (MRI) breast-tissue composition at age 21 years with prospectively collected measuremen...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwx358
更新日期：2018-06-01 00:00:00
abstract：:How can the "strengths" of risk factors, in the sense of how well they discriminate cases from controls, be compared when they are measured on different scales such as continuous, binary, and integer? Given that risk estimates take into account other fitted and design-related factors-and that is how risk gradients are...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwv193
更新日期：2015-11-15 00:00:00
abstract：:The relation between self-reported physical activity and depressive symptoms was analyzed for 1,900 healthy subjects aged 25-77 years in the Epidemiologic Follow-up Study (1982-1984) to the first National Health and Nutrition Examination Survey (NHANES I). Depressive symptomatology as measured by the Center for Epidem...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115087
更新日期：1988-12-01 00:00:00
abstract：:To assess the relation of increased mortality and morbidity to personal loss and damage following the 1988 earthquake in Armenia, the authors conducted a prospective study of mortality and a nested case-control analysis of incident morbidity. Employees of the Armenian Ministry of Health and their immediate families (n...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009585
更新日期：1998-12-01 00:00:00
abstract：:Plague (infection by Yersinia pestis) was present in Hawaii for the period 1899-1957 and caused at least 370 fatalities. The first infections came from immigrant commensal rats, probably Rattus rattus and Rattus norvegicus, on ships from the Orient. Both species were already established in Hawaii and became the widesp...
journal_title：American journal of epidemiology
pub_type： 历史文章,杂志文章
doi：10.1093/oxfordjournals.aje.a113745
更新日期：1984-02-01 00:00:00
abstract：:The relation between anesthetic gas exposure and spontaneous abortion remains unresolved. We examined the effect of nitrous oxide on spontaneous abortion among female dental assistants. Questionnaires were sent to 7,000 dental assistants aged 18-39 years who were registered in California in 1987; 4,856 (69%) responded...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117468
更新日期：1995-03-15 00:00:00
