[Off-line exhaled nitric oxide measurement in children].

Abstract:

INTRODUCTION:The objective is to test the validity of a tool allowing an offline measurement of the fraction of expired nitric oxide (FENO). The device is a T-tube on which a pressure gauge allows the control of the expiratory flow and whose two side branches have a gauge such as the bags assembled on each one of them fill successively. METHODS:The first phase aims to check that the sample collected in the second bag answers the criteria of analysis of NO during a single expiration and that this measurement can be delayed. The second phase aims to test the feasibility and the repeatability of the offline analysis in children. RESULTS:The device makes it possible to stabilize the expiratory flow at 100 ml/s. The NO concentration in the second bag is stable during 6 hours. The intra measurement coefficient of variation of delayed FENO 0.1 is 7% (N = 19). CONCLUSION:A off line measurement of the exhaled nitric oxide is reliable in asthmatic children.

journal_name

Rev Mal Respir

authors

Hamouda S,Chevalier-Bidaud B,Aboutaam R,Le Bourgeois M,Scheinmann P,Delclaux C,Mahut B

doi

10.1016/s0761-8425(06)71811-3

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

421-5

issue

5 Pt 1

eissn

0761-8425

issn

1776-2588

pii

MDOI-RMR-11-2006-23-5-0761-8425-101019-20064166

journal_volume

23

pub_type

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