Abstract:
:The aim of this work was to study the relationship between dynamic hyperinflation and dyspnoea perception on exercise in patients with chronic obstructive pulmonary disease (COPD). Seven men and three women with COPD (mean FEV1 45.9 +/- 9.8% predicted) were studied. The upper end of the visual analogue scale was anchored on a preliminary test on a cycle ergometer (day 1). On the study day (day 2) the relationship between dyspnoea and ventilatory indices during high intensity exercise was evaluated, using within-subject linear regression analysis. On a repeat study (day 3), the addition of inspiratory capacity (IC) manoeuvres allowed to monitor the end expiratory lung volume. The highest degree of within-subject correlation was observed between dyspnoea and the tidal peak inspiratory flow (PIFT), as well without (median r2 = 0.920, day 2) as with (median r2 = 0.880, day 3) IC manoeuvres. At maximal exercise, IC decreased in 8 out of 10 subjects (delta IC range -150 to -900 ml). A negative relationship was found between delta IC and the rate of increase in dyspnoea on exercise, measured as the dyspnoea/PIFT slope (r = 0.844, p < 0.01). Our results suggest that dynamic hyperinflation on exercise observed in most patients with COPD allows these subjects to minimize the rate of increase in dyspnoea on exercise.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Noseda A,Carpiaux JP,Schmerber J,Yernault JCsubject
Has Abstractpub_date
1993-01-01 00:00:00pages
537-43issue
6eissn
0761-8425issn
1776-2588journal_volume
10pub_type
杂志文章abstract:INTRODUCTION:Twenty five per cent of thermal injuries are associated with secondary respiratory events linked to several mechanisms. In the acute phase of the accident oedema of the airways, the fume inhalation syndrome and ARDS are the most common causes responsible for death in 60% of cases. Late respiratory complica...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(08)71553-5
更新日期:2008-03-01 00:00:00
abstract:INTRODUCTION:Mechanical ventilation is associated with ventilator-induced diaphragmatic dysfunction (VIDD) in animal models and also in humans. BACKGROUND:The main pathophysiological pathways implicated in VIDD seems to be related to muscle inactivity but may also be the consequence of high tidal volumes. Systemic ins...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2014.08.013
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:Patients suffering from sarcoidosis sometimes report dyspnoea of effort. The restrictive or obstructive ventilatory problems contribute to this disability, but the systemic manifestations of sarcoidosis should be considered as other possible causes of the dyspnoea. CASE REPORT:We report a case of systemic...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract:AIM:The main objective of the survey was to determine the frequency of the mono and polysensitizations in patients consulting for respiratory allergy, rhinitis or/and asthma. The secondary objectives were to evaluate the severity, the number and the type of the sensitizations, the frequency of the asthma or rhinitis as...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,多中心研究
doi:10.1016/s0761-8425(09)74670-4
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Optimal duration of first line chemotherapy for non surgical non small cell lung cancer (NSCLC) is still debated. It concerns the length of initial chemotherapy and the use of maintenance treatments. METHODS:Literature review was performed on maintenance and duration of chemotherapy. RESULTS:The use of mai...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:While wheezing disorders are common in preschool children, their management is not well defined. The aim of this study was to assess the use of medical health care resources due to wheezing disorders in infants aged 18 months followed up in the Pollution and Asthma Risk: an Infant Study (PARIS) birth cohort....
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2011.05.016
更新日期:2012-01-01 00:00:00
abstract::Current guidelines for referring patients with idiopathic pulmonary fibrosis (IPF) for lung transplantation, based on resting parameters, are insufficient to predict 3-year mortality. The aim of this study was to determine the prognostic value of cardio-pulmonary exercise testing (CPET) in patients with IPF. A multice...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,多中心研究
doi:10.1016/j.rmr.2010.08.016
更新日期:2011-03-01 00:00:00
abstract:STATE OF THE ART:The IRAD2 trial is evaluating a 3-month home intervention which includes education, oral supplements, exercise and androgenic steroids in undernourished patients with chronic respiratory failure. The main objective is to increase the six-minute walking distance by more than 50 m with an improvement in ...
journal_title:Revue des maladies respiratoires
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0761-8425(04)71362-5
更新日期:2004-06-01 00:00:00
abstract::One in a hundred pregnant females has asthma. Pregnancy may change the course of the asthma and inversely foetal and obstetric prognosis may be affected by the illness and by the potentially deleterious effect of treatment. The maternal physiological changes which occur during pregnancy throw little light on the varia...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1988-01-01 00:00:00
abstract::Chest radiograph and computed tomography are the most appropriate imaging tools for detecting asbestos-related pleural and parenchymal disease due to their availability and performances. The cost and irradiation delivery of conventional chest X-rays are limited. Technical parameters and reading should be standardized....
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:In order to achieve a better definition of the indications for surgical excision of pulmonary metastases in colorectal cancer (CCR), a retrospective study of the eight year survival of patients who had been operated on was carried out with reference to the principal prognostic factors. METHODS AND RESULTS:Be...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract:INTRODUCTION:Sarcoidosis is a systemic granulomatous disorder. However, when epithelioid cell granulomata are found in association with malignancy, they could correspond to a sarcoid reaction. CASE REPORT:We report the case of a young woman with mediastinal lymphadenopathy containing non-caseating granulomata. She als...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2012.05.009
更新日期:2012-09-01 00:00:00
abstract:INTRODUCTION:The objective is to test the validity of a tool allowing an offline measurement of the fraction of expired nitric oxide (FENO). The device is a T-tube on which a pressure gauge allows the control of the expiratory flow and whose two side branches have a gauge such as the bags assembled on each one of them ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(06)71811-3
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:In France, long-term follow-up after occupational exposure to asbestos is recommended. This study looked at the psychological consequences in the longer term following a CT-scan, in particular the impact of having received compensation for an occupational disease. METHODS:As part of an asbestos post-expos...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2019.06.009
更新日期:2019-10-01 00:00:00
abstract::Right ventricular failure (RVF) is a common cause of admission to the intensive care unit and its presence is a major prognostic factor in acute pulmonary embolism (PE) and chronic pulmonary hypertension (PH). RVF results from an incapacity of the RV to adapt to an increase in afterload so it can become critical in ac...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2019.07.012
更新日期:2020-02-01 00:00:00
abstract::An experimental model of lung obstruction has been achieved in the cat reared in our laboratory. 30 young adults (J) and one adult subject (A) had tracheal stenosis from 8 to 15 weeks and were the object of a study of pulmonary airways and were compared with four young controls and seven older controls. The presence o...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:INTRODUCTION:The epidemiology of chronic beryllium disease (CBD) in France is poorly understood. The aim of this study was to determine the number of prevalent cases of CBD in France between 2010 and 2014. METHODS:We conducted a national survey using a specific questionnaire distributed by the professional pathology s...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2020.03.003
更新日期:2020-05-01 00:00:00
abstract::The lung is directly affected by HIV virus early in the disease and is the site of a specific lymphocytic alveolitis. Neoplastic pulmonary disease linked to the virus occurs (Kaposi sarcoma, lymphoma and epidermoid tumour) but it is principally following opportunistic infections that patients with AIDS come under the ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:Pleural effusions are common in ICU patients. Causes include massive fluid resuscitation in shock, pneumonia--either community acquired or nosocomial, cardiac insufficiency, hypoalbuminemia and hepatic impairment. Pleural effusions frequently complicate cardiac and abdominal surgery and haemothorax may com...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/s0761-8425(05)85438-5
更新日期:2005-02-01 00:00:00
abstract::Meningeal metastases from malignant mesotheliomas are rarely observed. We report the case of a 54-year-old man with an asymptomatic pleural effusion and simultaneous sensitive and motor disorders of the right hemibody. A meningeal localization of a pleural malignant mesothelioma was discovered and confirmed by a compa...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract::We report seven cases of seven pulmonary varicella occurring in seven adults without any previous history of known immunological deficit. In all the cases the vesicular eruption was diffuse, occurring after contact with a child presenting with benign varicella. The respiratory signs appeared five to seven days after t...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::The development of fibreoptic bronchoscopy has enabled significant progress in the understanding of the pathogenesis of asthma. It has brought to the fore the importance of bronchial inflammation even in asymptomatic patients and/or in patients who have only mild disease. The practice of bronchial biopsy in vivo is an...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1998-06-01 00:00:00
abstract:INTRODUCTION:Breath-hold diving has been practised since the dawn of humanity but is open to many risks. The consequences mainly involve the respiratory system. The pathophysiological mechanisms are complex because of the multiple forces applied to the body during breath-hold diving. OBSERVATION:The case reported here...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(07)74263-8
更新日期:2007-11-01 00:00:00
abstract::Asbestos-related benign pleural lesions can involve the parietal pleura (pleural plaques), and/or visceral pleura as focal or diffuse (diffuse pleural thickening) fibrosis. Benign asbestos pleurisy and rounded atelectasis are linked with visceral pachypleuritis, the former as a cause, the latter as a consequence. The ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1999-12-01 00:00:00
abstract::The non bronchial systemic arterial circulation of the lung may, for more than one good reason, be considered as a third arterial circulation of the lung, after the bronchial and pulmonary circulation. A perfect knowledge of the anatomy of the circulation and the physiopathological mechanisms leading to its developmen...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::Fifty nine asthmatic children were assessed by skin tests (prick-tests) (TC), specific serum IgE level (R.A.S.T.) and bronchial provocation tests (TPB) with house dust, mites, grass pollen, animal scales and moulds. The concordance of the skin and R.A.S.T. tests with the provocation test, chosen for reference and thei...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Based on immunoassay techniques used to identify and quantify major indoor allergens, epidemiological studies have demonstrated that level of exposure depends on the geographical situation (climate, urbanization) and that there is a relationship between exposure and sensitization of predisposed patients. Most of the m...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:To define the role of interventional radiology and surgery respectively, in the treatment of massive haemoptysis. GENERAL CONSIDERATIONS: For the management of massive haemoptysis in non-terminal pathologies an intensive care facility and a multi-disciplinary team are necessary. It is of paramount importance ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(05)85635-9
更新日期:2005-11-01 00:00:00
abstract::An analysis of the way the pharyngeal musculature modulates the caliber of the pharynx is important to better understand and treat obstructive sleep apnea syndromes. The caliber of the pharynx at the soft palate depends on the action of the tensor veli, the palatoglossus, the palatopharyngeus and the uvula muscles. At...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1999-02-01 00:00:00
abstract:INTRODUCTION:Despite the development of international guidelines for the management of asthma, epidemiological surveys suggest that control of the disease remains poor. In order to investigate clinical practice a postal questionnaire was used to study the evaluation of asthma control, the assessment of factors associat...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(05)85475-0
更新日期:2005-04-01 00:00:00