Determination of oxidative stress status and concentration of TGF-beta 1 in the blood and saliva of osteoporotic subjects.

abstract：:Improved technology and medical advances have increased the lifespan for people with thalassemia. As thalassemia is no longer exclusively a pediatric blood disorder, consideration must now be given to transition planning from pediatric to adult care. The complexity of thalassemia disease, coupled with the changing fac...

journal_title：Annals of the New York Academy of Sciences

authors： Levine L,Levine M

更新日期：2010-08-01 00:00:00

abstract：:The aim of this study is to identify immune correlates of protection against tuberculosis induced by the current vaccine, Bacille Calmette Guerin (BCG). This knowledge should be valuable for developing and testing novel tuberculosis vaccines. Blood from 5675 10-week-old South African infants, routinely vaccinated with...

journal_title：Annals of the New York Academy of Sciences

authors： Hanekom WA

更新日期：2005-12-01 00:00:00

abstract：:Dipeptidyl peptidase IV (DPPIV) is a multifunctional cell surface aminopeptidase with ubiquitous expression and it has a variety of functional properties in the development of human malignancies. In the present study, we showed the possible correlation between DPPIV/CD26 expression and less migratory potential with de...

journal_title：Annals of the New York Academy of Sciences

authors： Kajiyama H,Shibata K,Terauchi M,Ino K,Nawa A,Kikkawa F

更新日期：2006-11-01 00:00:00

abstract：:The hypothalamus is one of the master regulators of various physiological processes, including energy balance and nutrient metabolism. These regulatory functions are mediated by discrete hypothalamic regions that integrate metabolic sensing with neuroendocrine and neural controls of systemic physiology. Neurons and no...

journal_title：Annals of the New York Academy of Sciences

authors： Cai D,Liu T

更新日期：2011-12-01 00:00:00

abstract：:An apparently macromolecular factor is isolated from aqueous skin extracts which inhibits DNA synthesis in vivo and in vitro with high efficacy (ID50 in vivo 0.2 pmol/g, in vitro 0.2 pM) and in a highly specific manner showing a point of attack in the late G1-phase of the cell cycle (epidermal G1-chalone). Preliminary...

journal_title：Annals of the New York Academy of Sciences

authors： Richter KH,Clauss M,Höfle W,Schnapke R,Marks F

更新日期：1988-01-01 00:00:00

abstract：:The receptive field of a direction-selective unit of any type consists of an excitatory center 3 degrees -5 degrees in size, a near inhibitory surround and a far surround upon which illumination exerts an influence for both spontaneous activity and specific cell response. ...

journal_title：Annals of the New York Academy of Sciences

authors： Golovkin M,Gorbunov V,Maximova E,Maximov V

更新日期：2005-06-01 00:00:00

abstract：:The availability of computer-controlled artificial hearts, kidneys, and lungs, as well as the possibility of implanting human embryos in ex vivo uterus models or an artificial endometrium, presents new perspectives for creating an artificial uterus. Survival rates have also improved, with fetuses surviving from as ear...

journal_title：Annals of the New York Academy of Sciences

authors： Bulletti C,Palagiano A,Pace C,Cerni A,Borini A,de Ziegler D

更新日期：2011-03-01 00:00:00

abstract：:Iddm4 is a dominant non-major histocompatibility complex (MHC) determinant of diabetes susceptibility in BBDR rats treated with poly I:C, plus depletion of regulatory T cells. In congenic MHC-identical normal WF rats, Iddm4(d) sensitively and specifically predicts induced diabetes. We report a new diabetes-susceptible...

journal_title：Annals of the New York Academy of Sciences

authors： Blankenhorn EP,Descipio C,Rodemich L,Cort L,Leif JH,Greiner DL,Mordes JP

更新日期：2007-04-01 00:00:00

abstract：:Despite intense efforts, little is known about the etiology of prostate cancer, and treatment of advanced forms of the disease has had limited success. Nonetheless, epidemiologic studies combined with animal model and in vitro experiments indicate that natural components of the diet, including n-3 PUFA, the carotenoid...

journal_title：Annals of the New York Academy of Sciences

authors： Cohen LA

更新日期：2002-06-01 00:00:00

abstract：:The studies described in this report suggest a rather complex, albeit incomplete, sequence of molecular events that we believe form part of the cascade of reactions through which a series of hormones, via cAMP, regulates the expression of specific gene products. The majority of our own studies relate to cAMP-mediated ...

journal_title：Annals of the New York Academy of Sciences

authors： Jungmann RA,Constantinou AI,Squinto SP,Kwast-Welfeld J,Schweppe JS

更新日期：1986-01-01 00:00:00

abstract：:Over most of the past century, it was thought that the adult brain was completely incapable of generating new neurons. However, in the last decade, the development of new techniques has resulted in an explosion of new research showing that (i) neurogenesis, the birth of new neurons, is not restricted to embryonic deve...

journal_title：Annals of the New York Academy of Sciences

authors： Arlotta P,Magavi SS,Macklis JD

更新日期：2003-06-01 00:00:00

abstract：:We evaluated immune and endocrine status following antituberculosis treatment in HIV-negative patients with newly diagnosed tuberculosis (TB). Treatment led to a decrease in IL-6, IL-1β, and C-reactive protein levels. Cortisol levels decreased throughout the anti-TB treatment, particularly after 4 months, but changes ...

journal_title：Annals of the New York Academy of Sciences

authors： Bongiovanni B,Díaz A,D'Attilio L,Santucci N,Dídoli G,Lioi S,Nannini LJ,Gardeñez W,Bogue C,Besedovsky H,del Rey A,Bottasso O,Bay ML

更新日期：2012-07-01 00:00:00

abstract：:The immunotherapeutic agent ipilimumab has helped address a significant unmet need in the treatment of advanced melanoma. Ipilimumab is a fully human monoclonal antibody that targets cytotoxic T-lymphocyte antigen-4 (CTLA-4), thereby augmenting antitumor immune responses. After decades in which a number of clinical tr...

journal_title：Annals of the New York Academy of Sciences

authors： Wolchok JD,Hodi FS,Weber JS,Allison JP,Urba WJ,Robert C,O'Day SJ,Hoos A,Humphrey R,Berman DM,Lonberg N,Korman AJ

更新日期：2013-07-01 00:00:00

abstract：:Since the first detection of highly pathogenic H5N1 avian influenza virus from sick goose in Guangdong province in China in 1996, scientists in China started to develop vaccines for avian influenza pandemic preparedness. An H5N2 inactivated vaccine was produced from a low pathogenic virus, A/turkey/England/N-28/73, an...

journal_title：Annals of the New York Academy of Sciences

authors： Qiao C,Tian G,Jiang Y,Li Y,Shi J,Yu K,Chen H

更新日期：2006-10-01 00:00:00

abstract：:Studies on host responses in sheep artificially infected with Theileria sp. (China) were discussed and summarized mainly on typical high fever periods, merozoits and schizoon observation, antibody response. ...

journal_title：Annals of the New York Academy of Sciences

authors： Wu JS,Yu JM,Wang ZL,Song CP,Yuan JF,Yao BA

更新日期：2006-10-01 00:00:00

abstract：:Although it is clear that thrombopoietin is the primary regulator of thrombopoiesis, several lines of evidence indicate that the hormone affects multiple aspects of hematopoiesis: the in vivo administration of TPO increases marrow levels of erythroid, myeloid, and megakaryocytic progenitor cells and its genetic elimin...

journal_title：Annals of the New York Academy of Sciences

authors： Kaushansky K

更新日期：2003-05-01 00:00:00

abstract：:Developmental dyslexia is associated with problems in a range of linguistic and non-linguistic skills. Some of those problems have been attributed to dysfunction of the cerebellum and its associated neural systems. Two studies of cerebellar structure were undertaken by our group. In Study 1, white and grey matter volu...

journal_title：Annals of the New York Academy of Sciences

authors： Laycock SK,Wilkinson ID,Wallis LI,Darwent G,Wonders SH,Fawcett AJ,Griffiths PD,Nicolson RI

更新日期：2008-12-01 00:00:00

abstract：:During relapses in relapsing-remitting multiple sclerosis (RRMS), serum soluble HLA class I surface antigen (sHLA-I) levels are reported to either decrease or remain unchanged, whereas serum sHLA-II levels increase. Interferon-beta1b therapy was recently reported to increase serum sHLA-I in RRMS. In the present prospe...

journal_title：Annals of the New York Academy of Sciences

authors： Minagar A,Adamashvilli I,Jaffe SL,Glabus MF,Gonzalez-Toledo E,Kelley RE

更新日期：2005-06-01 00:00:00

abstract：:Many autoimmune diseases are chronic conditions that progress over the course of years, and are characterized by the presence of autoantibodies that precede the overt disease by months or years. As examples, the presence of two islet cell antibodies (ICA) are associated with a 50% risk of developing diabetes mellitus ...

journal_title：Annals of the New York Academy of Sciences

authors： Harel M,Shoenfeld Y

更新日期：2006-06-01 00:00:00

abstract：:This paper describes the flight experiment, supporting ground science, and the design rationale for a project on spaceflight holography investigation in a virtual apparatus (SHIVA). SHIVA is a fundamental study of particle dynamics in fluids in microgravity. Gravitation effects and steady Stokes drag often dominate th...

journal_title：Annals of the New York Academy of Sciences

authors： Trolinger JD,L'Esperance D,Rangel RH,Coimbra CF,Witherow WK

更新日期：2004-11-01 00:00:00

abstract：:Sleep disturbances are prominent complaints of PTSD patients. Some, but not all, of the polysomnographic studies support the occurrence of sleep disruption. The main dimensions of sleep disturbance in the disorder relate to arousal regulation and REM-related functions of dreaming and memory processing. Both of these i...

journal_title：Annals of the New York Academy of Sciences

authors： Mellman TA

更新日期：1997-06-21 00:00:00

abstract：:This study aimed to assess the value of different DXA and BIA models for predicting muscle volume in mid-thigh segments obtained by MRI. Three DXA models were used: in model A, muscle was taken to be equivalent to fat-free soft tissue; in model B the thigh segment was divided into its constituent tissues using fixed a...

journal_title：Annals of the New York Academy of Sciences

authors： Elia M,Fuller NJ,Hardingham CR,Graves M,Screaton N,Dixon AK,Ward LC

更新日期：2000-05-01 00:00:00

abstract：:Alzheimer's disease (AD) is a heterogeneous and progressive neurodegenerative disease which in Western societies mainly accounts for clinical dementia. A high proportion of women are affected by this disease, especially at a very advanced age, which might to a large extent be associated with the fact that women live l...

journal_title：Annals of the New York Academy of Sciences

authors： Candore G,Balistreri CR,Grimaldi MP,Vasto S,Listì F,Chiappelli M,Licastro F,Lio D,Caruso C

更新日期：2006-11-01 00:00:00

abstract：:Emerging infectious diseases are of international concern because of the potential for, and impact of, pandemics; however, they are difficult to predict. To identify the drivers of disease emergence, we analyzed infectious disease threat events (IDTEs) detected through epidemic intelligence collected at the European C...

journal_title：Annals of the New York Academy of Sciences

authors： Semenza JC,Rocklöv J,Penttinen P,Lindgren E

更新日期：2016-10-01 00:00:00

abstract：:In a prospective investigation of perioperative cardiac edema formation requiring a delayed sternal closure, we identified thrombin increase combined with a simultaneous decrease of factor XIII as a probable cause. After experimental studies additionally revealed that factor XIII could protect endothelial barrier func...

journal_title：Annals of the New York Academy of Sciences

authors： Wozniak G,Noll T,Akintürk H,Thul J,Müller M

更新日期：2001-01-01 00:00:00

abstract：:Hepatitis B virus (HBV) of man has several characteristics that distinguish it from viruses of other groups. These include its ultrastructure, viral DNA size and structure, a virion DNA polymerase which repairs a single-stranded region in the viral DNA, liver tropism, character of persistent infection, and association...

journal_title：Annals of the New York Academy of Sciences

authors： Robinson WS

更新日期：1980-01-01 00:00:00

abstract：:The use of animal cells, tissues, or organs for humans is being investigated as an alternative to allotransplantation and as therapy for a broad range of disease states including diabetes, Parkinson's disease, and neurologic pain control. The risk of transmitting novel infections with these tissues, xenozoonoses, has ...

journal_title：Annals of the New York Academy of Sciences

authors： Michaels M

更新日期：1998-12-30 00:00:00

abstract：:Acylated aldose dialkyl dithioacetals with bromine undergo replacement of one alkylthio group by bromine. These unstable bromides react, as by fusion with 2,4-bis(trimethylsilyloxy)pyrimidine, to give acylated 1-(pyrimidin-1-yl) derivatives that upon saponification afford acyclic sugar nucleoside analogues, some as se...

journal_title：Annals of the New York Academy of Sciences

authors： Horton D,Baker DC,Kokrady SS

更新日期：1975-08-08 00:00:00

abstract：:To identify molecular genetic markers of resistance or susceptibility to dermatophilosis in cattle, we used a functional candidate gene approach to analyze the DNA polymorphisms of targeted genes encoding molecules implicated in known mechanisms of both nonspecific and specific immune responses existing in the pathoge...

journal_title：Annals of the New York Academy of Sciences

authors： Maillard JC,Chantal I,Berthier D,Thevenon S,Sidibe I,Razafindraibe H

更新日期：2002-10-01 00:00:00

abstract：:Vitamin E has the ability to scavenge a wide spectrum of free radicals, including singlet oxygen, superoxide, and hydroxyl radicals. It has beneficial effects against several other disorders, such as atherosclerosis and ischemic heart disease, because it acts as a transcriptional regulator for gene expression via a tr...

journal_title：Annals of the New York Academy of Sciences

authors： Al-Shamsi M,Amin A,Adeghate E

更新日期：2006-11-01 00:00:00