Plasmid patterns and in-vitro susceptibility of penicillinase-producing Neisseria gonorrhoeae with emphasis on thiamphenicol: results of surveillance in The Netherlands.

Abstract:

:Susceptibility to thiamphenicol was tested, and plasmids were characterized for 1925 strains of penicillinase-producing Neisseria gonorrhoeae (PPNG) isolated in The Netherlands in 1981 and 1982. Of the 1925 isolates, 771 harbored the so-called "Asia" (4.5-megadalton) resistance plasmid and 1154 had the so called "Africa" (3.2-megadalton) plasmid. Isolates in the first group were usually inhibited by 0.25 microgram of thiamphenicol ml, while the MIC for the latter isolates was 1-2 micrograms/ml. A similar bimodal distribution of MICs has been observed for non-PPNG isolates. In the period covering this study, a substantial shift from predominance of the "Africa" type to that of the "Asia" type of N. gonorrhoeae was observed.

journal_name

Sex Transm Dis

authors

van Klingeren B,van Wijngaarden LJ,Dessens-Kroon M

doi

10.1097/00007435-198410001-00011

subject

Has Abstract

pub_date

1984-10-01 00:00:00

pages

364-5

issue

4 Suppl

eissn

0148-5717

issn

1537-4521

journal_volume

11

pub_type

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