Topical pharmacotherapy for allergic rhinitis: new agents.

Abstract:

:The advantages of topical (as opposed to systemic) therapy for allergic rhinitis include the avoidance of undesirable systemic effects and the concentration of therapeutic effect on the target organ. Successful topical therapy requires establishment of a proper diagnosis, followed by effective delivery of the medication to the nasal mucosa. In addition to currently available preparations such as cromolyn sodium and various corticosteroids, several other topical nasal preparations for the treatment of allergic rhinitis are under investigation. These include antihistamines (eg, levocabastine), anti-inflammatory/mast cell stabilizing drugs (eg, nedocromil), new corticosteroids (eg, triamcinolone, budesonide, fluocortin, fluticasone), anticholinergics (eg, ipratropium), and miscellaneous agents (eg, HEPP [IgE pentapeptide]).

journal_name

South Med J

journal_title

Southern medical journal

authors

Mabry RL

doi

10.1097/00007611-199202000-00008

subject

Has Abstract

pub_date

1992-02-01 00:00:00

pages

149-54

issue

2

eissn

0038-4348

issn

1541-8243

journal_volume

85

pub_type

杂志文章,评审
  • A clinical report of adverse health effects due to bed sharing in two children with spinal cord injury and traumatic brain injury.

    abstract::This paper explores the possibility that bed sharing may carry particular risks for children with special healthcare needs (CSHCN). Two cases of CSHCN who may have sustained adverse health effects from bed sharing are described. These two case reports indicate that CSHCN may be particularly susceptible to risks associ...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/01.smj.0000220843.75686.cb

    authors: Sneed RC

    更新日期:2006-09-01 00:00:00

  • Fate of ovary transposed during treatment of Hodgkin's disease.

    abstract::Although successful transposition of the ovaries at the time of staging laparotomy for Hodgkin's disease is well documented, little comment has been made on potential complications. This case report of a primary ovarian neoplasm (benign) developing in a transposed ovary serves to alert physicians as to possible ovaria...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198307000-00039

    authors: Andersen WA,Chambers J,Wanebo HJ,Taylor PT

    更新日期:1983-07-01 00:00:00

  • Insurance status effects on stage of diagnosis and surgical options used in the treatment of breast cancer.

    abstract:OBJECTIVES:Insurance status has the potential to play a significant role in an individual's health care by affecting the time of diagnosis and the treatment options used. Our study reviewed insurance status as a determinant of the time of a breast cancer diagnosis as well as the surgical treatment options offered. MET...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.14423/SMJ.0000000000000281

    authors: Lukavsky R,Sariego J

    更新日期:2015-05-01 00:00:00

  • Splenic vein thrombosis.

    abstract::A retrospective review of all admissions to the University of Kentucky Medical Center from 1977 to 1987 revealed six persons in whom splenic vein thrombosis could be documented. The patients had either upper gastrointestinal bleeding from gastroesophageal varices or abdominal pain. Pancreatic disease was present in fi...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/00007611-199004000-00014

    authors: Simpson WG,Schwartz RW,Strodel WE

    更新日期:1990-04-01 00:00:00

  • Inappropriate admissions to psychiatric wards.

    abstract::Our seven clinical vignettes illustrate different mechanisms of inappropriate admissions to psychiatric wards and the circumstances and outcome of such admissions, with emphasis on the shared responsibility of psychiatric and nonpsychiatric physicians, the financial consequences, and the implications of such admission...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198507000-00014

    authors: Alarcon RD,Walter-Ryan WG,Shaw L

    更新日期:1985-07-01 00:00:00

  • Prevalence of Pancreatic Steatosis at a Pediatric Tertiary Care Center.

    abstract:OBJECTIVES:Pancreatic steatosis in adults has been proposed to be associated with obesity; however, data on pancreatic steatosis in children are lacking. Our study aimed to measure the prevalence of pancreatic steatosis in children and to examine its association with obesity and nonalcoholic fatty liver disease. METHO...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.14423/SMJ.0000000000000432

    authors: Pham YH,Bingham BA,Bell CS,Greenfield SA,John SD,Robinson LH,Eissa MA

    更新日期:2016-03-01 00:00:00

  • Dementia: physician approaches to the caregiver's problems.

    abstract::The demented patient requires medical and often psychiatric supervision, but the caregiver is often neglected. This article identifies special issues for caregivers that may need attention from the demented patient's physician. The physician's attention can benefit both the patient and the caregiver and save the physi...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:

    authors: Greene JA,Taylor SE,Johnson W

    更新日期:1993-09-01 00:00:00

  • Agenesis of the gallbladder--an inherited defect?

    abstract::Agenesis of the gallbladder is a rare anomaly believed to be an organogenetic failure. This is the third instance of familial agenesis of the gallbladder reported in the literature. The diagnosis of agenesis of the gallbladder can only be made during exploratory celiotomy and must be confirmed by an intraoperative nee...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197704000-00041

    authors: Sterchi JM,Baine RW,Myers RT

    更新日期:1977-04-01 00:00:00

  • Benign and malignant neoplasms in a family with Peutz-Jeghers syndrome: study of three generations.

    abstract::Three members of a family with Peutz-Jeghers syndrome had intussusception due to intestinal hamartomas. In addition, the grandfather had carcinoma of the jejunum, and the granddaughter had benign ovarian sex cord/stromal tumor causing sexual precocity. Benign and malignant tumors, not often associated with Peutz-Jeghe...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199110000-00011

    authors: Laughlin EH

    更新日期:1991-10-01 00:00:00

  • Sleep apnea syndromes.

    abstract::The sleep apnea syndromes have been recognized clinically in the United States only within the past ten years. The true extent of the problem is not known, but it seems certain that these syndromes are much more common than was generally assumed five years ago. Every clinician should be aware of the signs and symptoms...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/00007611-198201000-00011

    authors: Chaudhary BA,Speir WA Jr

    更新日期:1982-01-01 00:00:00

  • Hematologic Malignancies Discovered on Investigation of Breast Abnormalities.

    abstract:OBJECTIVES:Hematological malignancies of the breast share a presentation similar to primary breast carcinomas but differ substantially in therapeutic approach and clinical outcomes. In this study, we investigate the frequency of hematological malignancies, their relative primary and secondary occurrences, and further c...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.14423/SMJ.0000000000000710

    authors: Alsadi A,Lin D,Alnajar H,Brickman A,Martyn C,Gattuso P

    更新日期:2017-10-01 00:00:00

  • Superior vena cava syndrome: experience in a teaching hospital.

    abstract::Between 1972 and 1985, 39 patients with superior vena cava syndrome were admitted to the Medical College of Georgia Hospitals. I have reviewed the hospital courses of these patients and compared clinical and laboratory findings with those reported in previous series. The syndrome was malignant in 34 patients (mean age...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198710000-00011

    authors: Fincher RM

    更新日期:1987-10-01 00:00:00

  • Tissue expansion in the treatment of hypertrophic scars and scar contractures.

    abstract::The temporary tissue expander can generate an excess of full-thickness skin that can be recruited into an adjacent area of tissue deficiency caused by scar contracture. The creation of a pseudobursa enhances the functional improvement gained by this technique. Now in its developmental stage, tissue expansion carries a...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198604000-00011

    authors: Hagerty RC,Zubowitz VN

    更新日期:1986-04-01 00:00:00

  • Invasive group A streptococcal infections in Florida.

    abstract:BACKGROUND:Several previous studies of invasive Group A streptococcal (GAS) disease have been hindered by small sample sizes (< or = 100 patients) and limited generalizability. METHODS:We conducted a population-based study of invasive GAS disease. The objectives of the study were to describe the clinical features of i...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/01.SMJ.0000051060.95210.9A

    authors: Mulla ZD,Leaverton PE,Wiersma ST

    更新日期:2003-10-01 00:00:00

  • Bordetella bronchiseptica bacteremia in a patient with AIDS.

    abstract::Bordetella bronchiseptica bacteremia is often associated with various infection in animals. The majority of B bronchiseptica infections reported in humans are cases of pneumonia. Very few cases have been reported in patients with a history of acquired immune deficiency syndrome (AIDS). The patient described herein, wh...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/SMJ.0b013e3181ebcdbc

    authors: Mazumder SA,Cleveland KO

    更新日期:2010-09-01 00:00:00

  • Candida glabrata liver abscess and fungemia complicating severe calculus cholecystitis in an immunocompetent nondiabetic host.

    abstract::We report a rare case of Candida glabrata liver abscess and fungemia complicating severe calculus cholecystitis in a 64-year-old female patient who had no history of immunosuppression or diabetes mellitus. The patient underwent cholecystectomy, resection of liver abscess, and systemic antifungal therapy using micafung...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/SMJ.0b013e3181c9803b

    authors: Lima R,Shams W,Kalra S,Borthwick T

    更新日期:2010-03-01 00:00:00

  • Disseminated histoplasmosis and Wegener's granulomatosis.

    abstract::Disseminated histoplasmosis is an unusual complication in endemic areas and has been reported in patients with an immunodeficient state, either from human immunodeficiency virus (HIV) infection or transplantation. In the non-HIV population, rare cases of disseminated histoplasmosis have been reported in patients with ...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199812000-00012

    authors: Manepalli AN,Rush L

    更新日期:1998-12-01 00:00:00

  • Southern Regional Trophoblastic Disease Center, 1972--1977.

    abstract::The experience of the Southern Regional Trophoblastic Disease Center includes 222 patients who were referred from January 1972 to October 1977. The initial tissue diagnosis was hydatidiform mole in 212 patients and choriocarcinoma in ten. There was spontaneous remission of 142 (69%) of the moles and one of the chorioc...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197811000-00006

    authors: Hatch KD,Shingleton HM,Austin JM Jr,Boots LR,Younger JB,Soong SJ

    更新日期:1978-11-01 00:00:00

  • Chronic myelocytic leukemia with near-total pulmonary microvascular obstruction by platelets.

    abstract::We have described a patient with long-standing chronic granulocytic leukemia. Although most patients with this disorder eventually have a picture of acute leukemia (blast crisis), this patient had massive thrombocytosis (platelet count greater than 5.000 x 10(9)/L) without major symptoms, but he died after transfusion...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198804000-00029

    authors: Blachly RJ,Herring GF,Mansouri A

    更新日期:1988-04-01 00:00:00

  • Cranial migration of a lumboperitoneal shunt catheter.

    abstract::We describe a patient with pseudotumor cerebri for which a lumboperitoneal (LP) shunt was placed. After a pseudomeningocele was noted at the lumbar incision site, an LP shunt revision was done, at which time migration of the catheter into the thecal sac was noted. Three months later, radiologic studies revealed crania...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199606000-00019

    authors: Alleyne CH Jr,Shutter LA,Colohan AR

    更新日期:1996-06-01 00:00:00

  • Comparison of internal medicine, pediatric, and medicine/pediatrics applicants and factors influencing career choices.

    abstract:BACKGROUND:A reemergence of medical students choosing primary care is occurring, with medicine/pediatrics as an increasingly popular option. We compared applicants to pediatrics, medicine, and medicine/pediatrics and the factors that influence career choice. METHODS:We designed a survey to gather objective data and in...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199903000-00007

    authors: Doucet H,Shah MK,Cummings TL,Kahn MJ

    更新日期:1999-03-01 00:00:00

  • Effect of erythromycin on myocardial repolarization in patients with community-acquired pneumonia.

    abstract:BACKGROUND:Erythromycin has been associated with prolongation of myocardial repolarization and torsades de pointes (TdP). METHODS:To determine the frequency, dose-response, and risk factors for erythromycin-associated prolongation of myocardial repolarization, we observed data of patients admitted to our hospital with...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199912000-00009

    authors: Kdesh A,McPherson CA,Yaylali Y,Yasick D,Bradley K,Manthous CA

    更新日期:1999-12-01 00:00:00

  • Pneumococcal endocarditis in infants.

    abstract::A case of pneumococcal endocarditis in an infant is reported together with a review of seven cases previously described in the literature. The prominent presenting symptoms of this usually fatal disease consisted of tachycardia, tachypnea, and cardiomegaly. A new murmur was heard in six of the eight patients. Fever wa...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197904000-00021

    authors: Tolaymat A,Rhatigan RM,Levin S

    更新日期:1979-04-01 00:00:00

  • Simple method to predict digoxin serum concentration.

    abstract::The predictability of a method of determining serum digoxin concentration was assessed in a retrospective study of 35 hospitalized patients taking digoxin orally for maintenance therapy. Simple pharmacokinetic expressions were used to estimate digoxin concentration. Clinically, the mean measured digoxin concentration ...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198403000-00016

    authors: Shearer SW,Sawyer WT,Petteway SB Jr

    更新日期:1984-03-01 00:00:00

  • Changing role of radiotherapy in the management of cancer of the esophagus.

    abstract:BACKGROUND:Cancer of the esophagus remains a highly lethal disease, but new treatment approaches that build onto traditional surgical and radiotherapeutic methods are making an impact on organ preservation while offering hope for improved survival. METHODS:Reviewed here are recent data from trials on the use of new ra...

    journal_title:Southern medical journal

    pub_type: 临床试验,杂志文章,随机对照试验,评审

    doi:10.1097/00007611-199911000-00003

    authors: Rich T

    更新日期:1999-11-01 00:00:00

  • Spontaneous internal carotid artery dissection shown by magnetic resonance imaging.

    abstract::We have reported a case of spontaneous dissection of the internal carotid artery, with MRI and angiographic findings. We conclude that MRI is a beneficial noninvasive test for the detection and study of carotid artery dissection. ...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199109000-00021

    authors: Long TD,Carter MP,Reynolds T

    更新日期:1991-09-01 00:00:00

  • Orthopedic surgery postgraduate year 1 intern curriculum improves initial orthopedic in-training examination performance.

    abstract:OBJECTIVE:To determine the efficacy of an educational curriculum designed for orthopedic surgery postgraduate year 1 (PGY-1) interns to improve initial Orthopedic In-Training Examination (OITE) performance. METHODS:A retrospective cohort study was performed that evaluated the PGY-1 intern OITE performance of one resid...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/SMJ.0b013e31824fb9a4

    authors: Roberts CS,Nyland J,Broome B

    更新日期:2012-04-01 00:00:00

  • Five cranial nerve palsies in a diabetic man.

    abstract::A patient with stable non-insulin-dependent diabetes mellitus had five successive cranial nerve palsies, all of which resolved. This syndrome is rarely encountered in patients with diabetes and in otherwise healthy individuals. ...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198502000-00027

    authors: Brett AS

    更新日期:1985-02-01 00:00:00

  • Radiation therapy for early stage carcinoma of the glottic larynx.

    abstract::The results of radiation therapy of 79 patients with early carcinoma of the vocal cord are reported. Nine (13%) of the 69 patients with stage I disease had local recurrence, and two (20%) of the ten patients with stage II disease had local recurrence without local node metastasis. Subsequent control of radiation failu...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197901000-00004

    authors: Kim RY,Fincher JA,Roth RE

    更新日期:1979-01-01 00:00:00

  • Premalignant lesions of the anal margin.

    abstract::Premalignant lesions of the anal margin include Bowen's disease (intraepithelial squamous cell carcinoma) and Paget's disease (intraepithelial adenocarcinoma). Our experience includes 11 patients with perianal Paget's disease and 37 patients with perianal Bowen's disease treated from 1957 to 1986. The patients with pe...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198904000-00016

    authors: Beck DE,Fazio VW

    更新日期:1989-04-01 00:00:00