Changing role of radiotherapy in the management of cancer of the esophagus.

Abstract:

BACKGROUND:Cancer of the esophagus remains a highly lethal disease, but new treatment approaches that build onto traditional surgical and radiotherapeutic methods are making an impact on organ preservation while offering hope for improved survival. METHODS:Reviewed here are recent data from trials on the use of new radiotherapeutic approaches. RESULTS:There is clinical trial evidence for improved treatment results with radiotherapy and concurrent systemic chemotherapy. For some patients with responsive cancers, the use of chemoradiation results in about 25% being cured-a marked departure from the results of treatment with radiotherapy alone in the preceding decades. This idea is being explored further with new trials using advanced radiotherapy treatment planning systems called "conformal therapy," in which the high irradiation dose envelope is designed to fit tightly around the cancer. CONCLUSIONS:Cancer of the esophagus can now be treated aggressively with chemoradiation to offer a choice for local symptom control, organ preservation, and cure.

journal_name

South Med J

journal_title

Southern medical journal

authors

Rich T

doi

10.1097/00007611-199911000-00003

subject

Has Abstract

pub_date

1999-11-01 00:00:00

pages

1054-63

issue

11

eissn

0038-4348

issn

1541-8243

journal_volume

92

pub_type

临床试验,杂志文章,随机对照试验,评审
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    doi:10.1097/00007611-198107000-00018

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    abstract::In metabolic alkalosis, a compensatory decrease in alveolar ventilation with hypercapnia has been noted only rarely. We recently managed a patient with gastric outlet obstruction from a duodenal ulcer who survived after arriving in the emergency room comatose with severe hypochloremic metabolic alkalosis, compensatory...

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    更新日期:1986-10-01 00:00:00

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    authors: Mitas JA 2nd,Mosley CA Jr,Drager AM

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    authors: Stein DS,Libertin CR

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    authors: Hendren WG,Anderson T,Miller JI

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    abstract::HBsAg and anti-HBs positivity was determined in hospital laboratory workers and nonlaboratory hospital workers (controls) matched for race and sex and adjusted for age. The combined prevalence of antigen-antibody positivity among white female technicians was 12% versus 0 of controls (P less than 0.005). The highest pr...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197709000-00020

    authors: Wruble LD,Masi AT,Levinson MJ,Rightsell WA,Bale GF,Bertram P,Blackwell CF

    更新日期:1977-09-01 00:00:00

  • Facial diplegia due to amyloidosis.

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    pub_type: 杂志文章

    doi:10.1097/00007611-198611000-00037

    authors: Massey EW,Massey JM

    更新日期:1986-11-01 00:00:00

  • Treatment of myasthenic crisis in late life.

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    更新日期:1985-10-01 00:00:00

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    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:

    authors: North AF Jr

    更新日期:1977-10-01 00:00:00

  • Does physician benchmarking improve performance of laparoscopically assisted vaginal hysterectomy?

    abstract:BACKGROUND:Benchmarking techniques were implemented to optimize operating time and charges associated with laparoscopically assisted vaginal hysterectomy (LAVH). MATERIALS AND METHODS:The baseline LAVH profile over a period of 4 years (167 cases) was compared with 1-year data (47 cases) after a benchmarking educationa...

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    abstract::There is a lack of reliable serum biomarkers for routine use in the diagnostic workup of people with traumatic brain injury. Multiple biomediators and biomarkers have been described in the pertinent literature in recent years; however, only a few candidate molecules have been associated with high sensitivity and high ...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

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    authors: Neher MD,Keene CN,Rich MC,Moore HB,Stahel PF

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    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199912000-00009

    authors: Kdesh A,McPherson CA,Yaylali Y,Yasick D,Bradley K,Manthous CA

    更新日期:1999-12-01 00:00:00

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    authors: Harper HC 3rd,Maull KI

    更新日期:2000-07-01 00:00:00

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    doi:10.1097/00007611-198811000-00032

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  • Arterial distensibility in young normotensive subjects and in patients with borderline and essential hypertension.

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    authors: Aristimuño GG,Suarez DH

    更新日期:1984-01-01 00:00:00

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    doi:10.14423/SMJ.0000000000001160

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  • Prospective study of pneumonia: unexpected incidence of legionellosis.

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  • Primary small cell undifferentiated carcinoma of the rectum associated with ulcerative colitis.

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  • Doctoring: the philosophic milieu.

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  • Cronkhite-Canada syndrome with hypothyroidism.

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    abstract::I have reported two cases of Mallory-Weiss tear occurring after the patients drank an oral electrolyte/polyethylene glycol preparation before colonoscopy. Only two other such cases have been previously reported. ...

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  • Herpes simplex type 2 causing fulminant hepatic failure.

    abstract::Although exceedingly rare, fulminant hepatic failure (FHF) in immunocompetent patients can develop with primary or recurrent infection due to herpes simplex virus (HSV). The diagnosis is frequently obscured by the absence of mucocutaneous involvement. Elevated transaminase values with leukopenia and a relatively low b...

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    doi:

    authors: Fahy RJ,Crouser E,Pacht ER

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  • Enhanced vs Standard Parents as Teacher Curriculum on Factors Related to Infant Feeding among African American Women.

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    journal_title:Southern medical journal

    pub_type: 杂志文章,随机对照试验

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    pub_type: 杂志文章

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    authors: Buchino JJ,Buchino JJ

    更新日期:1998-11-01 00:00:00

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    更新日期:2014-11-01 00:00:00

  • Aberrant internal carotid artery.

    abstract::An aberrant internal carotid artery (ICA) in the middle ear is rare. If unrecognized, it may lead to massive hemorrhage or other catastrophic results during even a minor surgical procedure of the tympanic membrane or middle ear. Recognition of this entity is particularly significant to the primary care or emergency de...

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    pub_type: 杂志文章

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    更新日期:1994-12-01 00:00:00

  • Dinitrophenol poisoning: a diagnosis to consider in undiagnosed fever.

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    doi:

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    更新日期:1982-02-01 00:00:00

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    abstract::The comparative value of palpation, light percussion, and auscultatory percussion for detecting the liver below costal margin was studied in 45 normal subjects and 20 patients. The presence of the liver 2 cm or more below the costal margin was considered abnormal, since this organ was found no more than 1 cm below in ...

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  • A Multidisciplinary Approach to Castleman Disease of the Neck.

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