Abstract:
BACKGROUND:Cancer of the esophagus remains a highly lethal disease, but new treatment approaches that build onto traditional surgical and radiotherapeutic methods are making an impact on organ preservation while offering hope for improved survival. METHODS:Reviewed here are recent data from trials on the use of new radiotherapeutic approaches. RESULTS:There is clinical trial evidence for improved treatment results with radiotherapy and concurrent systemic chemotherapy. For some patients with responsive cancers, the use of chemoradiation results in about 25% being cured-a marked departure from the results of treatment with radiotherapy alone in the preceding decades. This idea is being explored further with new trials using advanced radiotherapy treatment planning systems called "conformal therapy," in which the high irradiation dose envelope is designed to fit tightly around the cancer. CONCLUSIONS:Cancer of the esophagus can now be treated aggressively with chemoradiation to offer a choice for local symptom control, organ preservation, and cure.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Rich Tdoi
10.1097/00007611-199911000-00003subject
Has Abstractpub_date
1999-11-01 00:00:00pages
1054-63issue
11eissn
0038-4348issn
1541-8243journal_volume
92pub_type
临床试验,杂志文章,随机对照试验,评审abstract::Severe lactic acidosis is often associated with poor prognosis. Recognition and correction of the underlying process is the major step in the treatment of this serious condition. Intravenous administration of sodium bicarbonate has been the mainstay in the treatment of lactic acidosis. Aggressive use of this therapeut...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198107000-00018
更新日期:1981-07-01 00:00:00
abstract::In metabolic alkalosis, a compensatory decrease in alveolar ventilation with hypercapnia has been noted only rarely. We recently managed a patient with gastric outlet obstruction from a duodenal ulcer who survived after arriving in the emergency room comatose with severe hypochloremic metabolic alkalosis, compensatory...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198610000-00025
更新日期:1986-10-01 00:00:00
abstract::Seven patients with diabetes of ten to 24 years' duration and renal insufficiency were treated with fluphenazine and amitriptyline in an attempt to control severe pain in the extremities. Six patients had relief of pain within five days of initiation of therapy. One patient had no pain relief despite mood alteration. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1983-04-01 00:00:00
abstract::Coagulopathy due to tuberculosis is rare. We believe ours is only the second reported case of cavitary tuberculosis associated with disseminated intravascular coagulation. Our review of all 13 cases to date shows that the patients are generally black, middle-aged, male, alcoholic, and febrile. The tuberculosis is gene...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199001000-00019
更新日期:1990-01-01 00:00:00
abstract::Massive bleeding from a pharyngoesophageal diverticulum is a rarely reported condition, with only two reported cases in the literature. This report describes a patient who had massive bleeding due to ulceration in the base of a pharyngoesophageal diverticulum, presumed to have been caused by chronic aspirin ingestion....
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199003000-00033
更新日期:1990-03-01 00:00:00
abstract::HBsAg and anti-HBs positivity was determined in hospital laboratory workers and nonlaboratory hospital workers (controls) matched for race and sex and adjusted for age. The combined prevalence of antigen-antibody positivity among white female technicians was 12% versus 0 of controls (P less than 0.005). The highest pr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197709000-00020
更新日期:1977-09-01 00:00:00
abstract::In a 61-year-old man with facial diplegia and new onset of congestive heart failure (CHF), electroneuromyography indicated diffuse axonal degeneration, but sural nerve biopsy showed mild changes and no amyloid. Four months later, after the onset of diplopia and increasing CHF, rectal biopsy demonstrated amyloid. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198611000-00037
更新日期:1986-11-01 00:00:00
abstract::In 32 patients with the onset of myasthenia gravis after age 50, myasthenic crisis occurred in 53% and persisted for a mean of 33 days (range six to 84 days). Three of the patients had a second crisis. Precipitating factors were found in 60% of the episodes. Treatment of 20 episodes of crisis resulted in excellent rec...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198510000-00017
更新日期:1985-10-01 00:00:00
abstract::To date, screening has largely failed to fulfill the hope that early detection would lead to more effective early treatment and to improved health status in the population served. The future role of screening can be much more positive but only if (1) screening is directed only at diseases and conditions for which earl...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1977-10-01 00:00:00
abstract:BACKGROUND:Benchmarking techniques were implemented to optimize operating time and charges associated with laparoscopically assisted vaginal hysterectomy (LAVH). MATERIALS AND METHODS:The baseline LAVH profile over a period of 4 years (167 cases) was compared with 1-year data (47 cases) after a benchmarking educationa...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000176713.71878.63
更新日期:2005-09-01 00:00:00
abstract::There is a lack of reliable serum biomarkers for routine use in the diagnostic workup of people with traumatic brain injury. Multiple biomediators and biomarkers have been described in the pertinent literature in recent years; however, only a few candidate molecules have been associated with high sensitivity and high ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0000000000000086
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Erythromycin has been associated with prolongation of myocardial repolarization and torsades de pointes (TdP). METHODS:To determine the frequency, dose-response, and risk factors for erythromycin-associated prolongation of myocardial repolarization, we observed data of patients admitted to our hospital with...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199912000-00009
更新日期:1999-12-01 00:00:00
abstract::Patients with blunt hepatic injury can safely be managed nonoperatively if they show hemodynamic stability. Transcatheter arterial embolization (TAE) is a useful adjunct in the treatment of patients who show evidence of continued hemorrhage or who have pooling of contrast material on computed tomography (CT). In these...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract::To make informed career decisions, physicians must acquire a basic knowledge in medical management and health care economics as they evaluate the potential survival and growth of a primary care practice. Health care providers considering a specific community and local leaders and hospital administrators attempting to ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199404000-00006
更新日期:1994-04-01 00:00:00
abstract::Clinicians should be on the alert for the possibility of underlying thyrotoxicosis in patients having an affective disturbance. An initial detailed medical history and complete physical examination is essential even in severely agitated, threatening patients. The danger of inappropriate diagnosis and treatment of thes...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198811000-00032
更新日期:1988-11-01 00:00:00
abstract::We evaluated the indices of arterial distensibility in a group (N = 40) of normotensive subjects and patients with borderline or established hypertension by measuring intra-arterial pressure, pulse wave velocity, and a mathematical modification of MOEN's formula to calculate arterial distensibility. Multiple linear re...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198401000-00015
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVE:To determine the association of utilization of health maintenance tables (HMTs) as a provider reminder tool within the electronic medical record with the completion of women's preventive health services. METHODS:Guidelines from the US Preventive Services Task Force and the Advisory Committee on Immunization ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000001160
更新日期:2020-10-01 00:00:00
abstract::In a prospective study of the etiology of pneumonia in patients hospitalized at a university hospital, all respiratory secretions were tested for routine pathogens as well as Legionella. A diagnosis was established in 60 of 87 patients studied. Of the 37 nosocomial infections, six were caused by L micdadei. Gram-negat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198604000-00007
更新日期:1986-04-01 00:00:00
abstract::Primary small cell undifferentiated carcinomas (SCUCs) are unusual tumors of the colon and rectum. Histologically, these lesions represent a spectrum of neuroendocrine differentiation, with oat cell carcinoma being the most primitive subtype and carcinoid tumors being the most differentiated. This observation is suppo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199609000-00016
更新日期:1996-09-01 00:00:00
abstract::To understand fully a physician's role in society, and to deal successfully with the current sense of crisis, the medical profession must evolve a world-view that appropriately relates a physician to the patient, to the practice environment, to the base of knowledge, and to the physician's own sense of self. Such a wo...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198812000-00022
更新日期:1988-12-01 00:00:00
abstract::Cronkhite-Canada syndrome is a rare, noninherited gastrointestinal polyposis syndrome associated with characteristic ectodermal abnormalities. This report describes a 60-year-old female who was diagnosed with Cronkhite-Canada syndrome with hypothyroidism after presenting with chronic diarrhea, alopecia, intermittent a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000157528.71614.C4
更新日期:2005-05-01 00:00:00
abstract::I have reported two cases of Mallory-Weiss tear occurring after the patients drank an oral electrolyte/polyethylene glycol preparation before colonoscopy. Only two other such cases have been previously reported. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199203000-00021
更新日期:1992-03-01 00:00:00
abstract::Although exceedingly rare, fulminant hepatic failure (FHF) in immunocompetent patients can develop with primary or recurrent infection due to herpes simplex virus (HSV). The diagnosis is frequently obscured by the absence of mucocutaneous involvement. Elevated transaminase values with leukopenia and a relatively low b...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVES:To determine the comparative impact of the standard Parents as Teachers (PAT) to the nutrition and physical activity enhanced version (PATE) of the perinatal educational curriculum on compliance with infant feeding recommendations and changes in maternal infant feeding knowledge and beliefs. METHODS:Women a...
journal_title:Southern medical journal
pub_type: 杂志文章,随机对照试验
doi:10.14423/SMJ.0000000000001024
更新日期:2019-10-01 00:00:00
abstract::Thoracic splenosis is rare, with fewer than two dozen reported cases. Patients uniformly have a history of splenectomy with combined abdominal and thoracic trauma. Clinical signs and symptoms are usually absent, and the condition is most often discovered on routine chest radiography. The interval between trauma and cl...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199811000-00013
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVES:Total annual costs for syncope-related hospitalizations were $2.4 billion in 2000. The aim of this study was to examine the type and number of tests ordered for patients admitted with syncope and whether these tests helped establish the cause. METHODS:We studied the records of 1038 patients coded as "syncop...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000184
更新日期:2014-11-01 00:00:00
abstract::An aberrant internal carotid artery (ICA) in the middle ear is rare. If unrecognized, it may lead to massive hemorrhage or other catastrophic results during even a minor surgical procedure of the tympanic membrane or middle ear. Recognition of this entity is particularly significant to the primary care or emergency de...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199412000-00014
更新日期:1994-12-01 00:00:00
abstract::A 32-year-old farmer had signs and symptoms of dinitrophenol poisoning after crop spraying with a herbicide containing derivatives of 2,4-dinitrophenol. Dinitrophenol causes toxicity by the uncoupling of oxidative phosphorylation in the mitochondria of cells throughout the body. In man the classic syndrome consists of...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1982-02-01 00:00:00
abstract::The comparative value of palpation, light percussion, and auscultatory percussion for detecting the liver below costal margin was studied in 45 normal subjects and 20 patients. The presence of the liver 2 cm or more below the costal margin was considered abnormal, since this organ was found no more than 1 cm below in ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199402000-00006
更新日期:1994-02-01 00:00:00
abstract::Castleman disease (CD) is a rare lymphoproliferative disorder that occurs in adults and rarely in the pediatric population. The disease is characterized by slowly enlarging masses that can form anywhere within the lymphatic system. It is an uncommon cause of a neck mass in both children and adults that presents insidi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000406
更新日期:2016-02-01 00:00:00