Marked hypochloremic metabolic alkalosis with severe compensatory hypoventilation.

Abstract:

:In metabolic alkalosis, a compensatory decrease in alveolar ventilation with hypercapnia has been noted only rarely. We recently managed a patient with gastric outlet obstruction from a duodenal ulcer who survived after arriving in the emergency room comatose with severe hypochloremic metabolic alkalosis, compensatory hypoventilation, and hypercapnia. We know of no report in the English literature of a patient with gastric outlet obstruction having a respiratory acidosis or hypochloremia as severe as that in our patient. Proper understanding of the pathophysiology of primary metabolic alkalosis due to gastric losses is necessary to correct the acid-base abnormalities quickly and to restore normal alveolar ventilation.

journal_name

South Med J

journal_title

Southern medical journal

authors

Lavie CJ,Crocker EF Jr,Key KJ,Ferguson TG

doi

10.1097/00007611-198610000-00025

subject

Has Abstract

pub_date

1986-10-01 00:00:00

pages

1296-9

issue

10

eissn

0038-4348

issn

1541-8243

journal_volume

79

pub_type

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