Abstract:
:Premalignant lesions of the anal margin include Bowen's disease (intraepithelial squamous cell carcinoma) and Paget's disease (intraepithelial adenocarcinoma). Our experience includes 11 patients with perianal Paget's disease and 37 patients with perianal Bowen's disease treated from 1957 to 1986. The patients with perianal Paget's disease were older, had a higher incidence of invasive cancer, and had a worse prognosis than those with perianal Bowen's disease. The characteristic appearance of these lesions and their failure to respond to conventional therapy should lead the clinician to obtain a biopsy, which readily establishes the diagnosis. Our experience confirms that adequate evaluation followed by wide local excision is the appropriate therapy. Close follow-up is recommended to identify recurrence of the perianal disease or development of other malignancies.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Beck DE,Fazio VWdoi
10.1097/00007611-198904000-00016subject
Has Abstractpub_date
1989-04-01 00:00:00pages
470-4issue
4eissn
0038-4348issn
1541-8243journal_volume
82pub_type
杂志文章abstract::Cyclosporine is a fungal metabolite increasingly used as an immunosuppressive agent in organ transplantation. It provides immunosuppression primarily through reversible inhibition of T-lymphocytes, without myelotoxicity. Cyclosporine appears to inhibit primary activation of helper cells and to decrease the production ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198602000-00017
更新日期:1986-02-01 00:00:00
abstract::We describe two patients who had tuberculomas that were initially misdiagnosed as neurosarcoidosis, leading to prolonged steroid therapy before initiation of antituberculous medications. Neither patient was infected with the human immunodeficiency virus, and one of the patients had a negative tuberculosis skin test. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000048150.02504.99
更新日期:2003-05-01 00:00:00
abstract::Cantharidin in either a 0.9% or 0.7% solution is a safe and effective office treatment for molluscum contagiosum. It simplifies the treatment, especially of children, by being a quick, simple, and painless procedure, but it should be applied only by the physician. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1979-08-01 00:00:00
abstract::Coronary artery spasm can occur in the presence of excessive alpha-adrenergic tone. A decrease in protective coronary vasodilator substance and enhanced alpha-adrenergic responsiveness, which occurs in the setting of hypothroidism and beta blockade, predisposes to coronary artery spasm. The case presented supports the...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197907000-00004
更新日期:1979-07-01 00:00:00
abstract::An infected echinococcal cyst of the liver was diagnosed in a 48-year-old male immigrant from Spain. After preoperative treatment with mebendazole, microscopic examination of the operative cyst contents showed no viable scoleces or brood capsules of Echinococcus. We recommend the preoperative use of mebendazole in the...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1986-07-01 00:00:00
abstract::Thirty-three anterior staple capsulorrhaphies of the shoulder were reviewed at an average 49.7 months postoperatively (range 12 to 127 months); one postoperative dislocation occurred. The patients' quality of athletic participation improved with surgical therapy in 50%, remained the same in 38%, and was lowered in 12%...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199005000-00009
更新日期:1990-05-01 00:00:00
abstract::A combined patient flow and work sampling study was done at the Ambulatory Pediatric Service of the Medical University of South Carolina. The biggest problem was that almost two thirds of the patient's time was spent waiting to see the doctor. Reasons for delay included too few examining rooms, the single block appoin...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197706000-00004
更新日期:1977-06-01 00:00:00
abstract::A leg ulcer in a 52-year-old renal transplant patient yielded foamy histiocytes containing acid-fast bacilli subsequently identified as a Runyon group III Mycobacterium. Skin infection with these organisms is unusual, and the histologic appearance in this case suggested lepromatous leprosy. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198708000-00033
更新日期:1987-08-01 00:00:00
abstract::Concurrent occurrence of carotid artery stenosis and intracerebral aneurysm is uncommon and poses a therapeutic dilemma. We report a patient with bilateral carotid artery stenosis and a 2.5 cm left middle cerebral artery aneurysm who simultaneously underwent a successful stent-assisted coiling for his intracerebral an...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000217190.93989.c9
更新日期:2006-07-01 00:00:00
abstract::We report the case of a 29-year-old woman who had acute cytomegalovirus hepatitis superimposed on previously unrecognized chronic hepatitis B infection. We then review the diagnostic approach to acute hepatitis and positive hepatitis B surface antigen. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199612000-00017
更新日期:1996-12-01 00:00:00
abstract::In the ten-year period from 1978 through 1987, 261 patients with intussusception were admitted to Chang Gung Memorial Hospital. The diagnosis was established by barium enema or at laparotomy. The patients were divided into two groups; there were 228 children ranging in age from 1 month to 14 years, and 33 adults. Amon...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract:OBJECTIVES:Adherence to National Comprehensive Cancer Network (NCCN) guidelines for ovarian cancer treatment improves patient outcomes. The aim of this study was to assess disparities associated with ovarian cancer treatment in the state of Kentucky and central Appalachia. METHODS:Data on patients diagnosed as having ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000821
更新日期:2018-06-01 00:00:00
abstract::Primary biliary cirrhosis (PBC) is a cholestatic liver disease that usually presents in middle-aged women. Women are about ten times more commonly affected than men. The case of a 78-year-old man with PBC who presented with pruritus is discussed. Liver biopsy and antimitochondrial antibody serology were diagnostic of ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181c041bd
更新日期:2009-12-01 00:00:00
abstract::We present information describing how to search to identify those reports that provide insight into the answer to the query. We have presented a reasonable approach to searching, with our end-point being the identification of published articles which appear to answer our queries. The decision as to whether these artic...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e31824a711f
更新日期:2012-03-01 00:00:00
abstract::In children, intramural duodenal hematomas resulting from blunt abdominal trauma are generally managed nonoperatively with nasogastric suction and parenteral nutrition. Experience with three cases in which this form of treatment failed caused us to reappraise its benefits and results. Consequently, we now recommend su...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198808000-00011
更新日期:1988-08-01 00:00:00
abstract::Most nonendocrine pancreatic neoplasms are adenocarcinomas of ductal cell or acinar origin. Primary carcinomas of the pancreas with squamous differentiation are rare enough to warrant a search for other primary tumors. In the past few decades, well-documented individual reports and large series reviews support the vie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::Highly trained medical specialists now possess a vast array of sophisticated technical apparatus with which to fight diseases. These tools, coupled with a growing emphasis on cost accounting and a medical paradigm emphasizing facts and depicting the human body as a machine, depersonalize health care by militating agai...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199307000-00017
更新日期:1993-07-01 00:00:00
abstract::A woman with stable diabetes presented with hypoglycemia and decreased insulin requirement. Further history suggested decreasing pituitary function. Laboratory tests confirmed pituitary deficiencies, associated with her increased insulin sensitivity. It may be helpful to be aware of this syndrome when dealing with dia...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198001000-00033
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVE:To provide a succinct and updated discussion on common ear, nose, and throat (ENT) disorders encountered by primary care physicians. METHODS:Review of recent and pertinent literature. RESULTS:Recent data was identified via a PubMed search as well as commonly utilized texts in otolaryngology. DISCUSSION:Whi...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000233214.49561.c1
更新日期:2006-10-01 00:00:00
abstract::We have described a case of thrombocytopenic purpura caused by methyldopa. A methyldopa-dependent antiplatelet antibody as the mechanism of the patient's thrombopenia was suggested by a positive clot retraction inhibition test. This simple in vitro test should be done more often in suspected cases of drug-induced thro...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198203000-00036
更新日期:1982-03-01 00:00:00
abstract::Compartment syndrome of the leg is usually associated with significant trauma. It has also been associated with prolonged surgery in the hemilithotomy position. Fracture tables that are used for the internal fixation of proximal femur fractures under fluoroscopy place a patient in this position. This report chronicles...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00
abstract::In an attempt to prevent morbidity and mortality in carotid endarterectomy, we monitored 47 operations with intraoperative EEG to determine which patients should have a shunt during endarterectomy. The EEG was recorded for up to five minutes during test carotid cross-clamping. When EEG asymmetry between the cerebral h...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197908000-00018
更新日期:1979-08-01 00:00:00
abstract::Two patients with polycystic kidney disease and renal failure developed profound hypotension within 30 minutes after starting hemodialysis. After ruling out all recognized causes of hypotension during early dialysis, we found that their vena cavas were obstructed by compression of the vessels against the spinal column...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197911000-00013
更新日期:1979-11-01 00:00:00
abstract::Primary squamous cell carcinoma of the breast is a rare cancer. Published reports of prognosis are variable, and most studies are case reports of one or a few patients. We report an additional case of squamous cell carcinoma of the breast occurring in a 53-year-old black woman. In reviewing the reported cases of this ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199605000-00013
更新日期:1996-05-01 00:00:00
abstract::A technic incorporating the simultaneous elevation of multiple adjacent thoracoabdominal pedicale flaps, based in opposite directions, has been successfully used on four patients with extensive degloving injuries of the hand. In all cases, the hand was later divided into individual digits. A five-year follow-up of thr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197803000-00024
更新日期:1978-03-01 00:00:00
abstract::Through a cooperative study, 87 ocular injuries caused by class C fireworks have been recorded in the State of Arkansas over a four-year period. The most common injuries were corneal abrasion, lid laceration or burn, and hyphema. Rockets and firecrackers caused 80% of the injuries. In over half the cases there was mod...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract:BACKGROUND:Tobacco use causes significant morbidity and mortality. Resident physicians at the George Washington University Medical Center are trained to counsel patients to stop smoking. METHODS:I retrospectively reviewed charts of 300 patients treated by resident physicians in the Department of Medicine (200) and the...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199910000-00007
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVES:Alloantibody formation secondary to transfusion in patients with sickle cell disease (SCD) is a well-known phenomenon. Pretransfusion testing (eg, "antibody screening") protects patients from receiving incompatible red blood cell transfusions. Because alloantibodies have a tendency to evanesce (ie, become un...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000528
更新日期:2016-09-01 00:00:00
abstract::Elevation in fasting serum gastrin levels was found in three patients being evaluated for persistent upper abdominal pain without radiographic evidence of peptic ulcer disease. Fiberoptic endoscopy of the upper gastrointestinal tract in each patient revealed characteristic changes of chronic atrophic gastritis. Gastri...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197612000-00010
更新日期:1976-12-01 00:00:00
abstract::We present the first two known cases of infantile botulism in Oklahoma. The first case was due to type B toxin; the second was due to type A toxin. Both cases demonstrate most of the classic features of what now appears to be the most common form of botulism. Infantile botulism is an underrecognized but reversible cau...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198804000-00012
更新日期:1988-04-01 00:00:00