A feasibility study of using conventional jaws to deliver IMRT plans in the treatment of prostate cancer.

Abstract:

:The aim of this study is to investigate the feasibility of using conventional jaws to deliver inverse planned intensity-modulated radiotherapy (IMRT) plans for patients with prostate cancer. For ten patients, each had one three-dimensional conformal plan (3D plan) and seven inverse IMRT plans using direct aperture optimization. For IMRT plans using conventional jaws (JO plans), the number of apertures per beam angle was set from two to seven while three apertures per beam angle were set for the multi-leaf collimator (MLC) plans. To evaluate each planning method, we compared average dose volume histograms (DVH), the conformal index (COIN), total number of segments and total number of monitor units. Among the JO plans with the number of apertures per beam angle varying from two to seven, no difference was observed in the average DVHs, and the plan conformal index became saturated after four apertures per beam angle. Subsequently, JO plans with four apertures per beam angle (JO-4A) were compared with 3D and MLC plans. Based on the average DVHs, no difference was found among 3D, JO-4A and MLC plans with regard to the planning target volume and rectum, but the DVHs for the bladder and penile bulb were significantly better with inverse IMRT plans than those with 3D plans. When compared with the plan conformity, the average COIN values for 3D, JO-4A and MLC plans were 0.61 +/- 0.07, 0.73 +/- 0.05 and 0.83 +/- 0.05, respectively. In conclusion, inverse IMRT plans using conventional jaws are clinically feasible, achieving better plan quality than 3D-CRT plans.

journal_name

Phys Med Biol

authors

Kim Y,Verhey LJ,Xia P

doi

10.1088/0031-9155/52/8/007

subject

Has Abstract

pub_date

2007-04-21 00:00:00

pages

2147-56

issue

8

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(07)38965-3

journal_volume

52

pub_type

杂志文章,随机对照试验
  • An integrated quality assurance phantom for frameless single-isocenter multitarget stereotactic radiosurgery.

    abstract::Brain stereotactic radiosurgery (SRS) treatments require multiple quality assurance (QA) procedures to ensure accurate and precise treatment delivery. As single-isocenter multitarget SRS treatments become more popular, the quantification of off-axis accuracy of the linear accelerator is crucial. In this study, a novel...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab8534

    authors: Capaldi DPI,Skinner LB,Dubrowski P,Yu AS

    更新日期:2020-06-10 00:00:00

  • Monte Carlo-based diffusion tensor tractography with a geometrically corrected voxel-centre connecting method.

    abstract::Diffusion tensor tractography (DTT) allows one to explore axonal connectivity patterns in neuronal tissue by linking local predominant diffusion directions determined by diffusion tensor imaging (DTI). The majority of existing tractography approaches use continuous coordinates for calculating single trajectories throu...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/4/013

    authors: Bodammer NC,Kaufmann J,Kanowski M,Tempelmann C

    更新日期:2009-02-21 00:00:00

  • Fast and exact Hessian computation for a class of nonlinear functions used in radiation therapy treatment planning.

    abstract::In nonlinear optimisation, using exact Hessian computations (full-Newton) hold superior convergence properties over quasi-Newton methods or gradient-based methods. However, for medium-scale problems, computing the Hessian can be computationally expensive and thus time-consuming. For solvers dedicated to a specific pro...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab1e17

    authors: van Haveren R,Breedveld S

    更新日期:2019-08-14 00:00:00

  • Optimization-based image reconstruction with artifact reduction in C-arm CBCT.

    abstract::We investigate an optimization-based reconstruction, with an emphasis on image-artifact reduction, from data collected in C-arm cone-beam computed tomography (CBCT) employed in image-guided interventional procedures. In the study, an image to be reconstructed is formulated as a solution to a convex optimization progra...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/20/7300

    authors: Xia D,Langan DA,Solomon SB,Zhang Z,Chen B,Lai H,Sidky EY,Pan X

    更新日期:2016-10-21 00:00:00

  • The photon calibration of a tissue-equivalent ionisation chamber for neutron dosimetry.

    abstract::The poor agreement in the photon calibrations of tissue-equivalent ionisation chambers between different participants in two major neutron dosimetry intercomparisons is noted. The methods of converting measurements made with a calibrated secondary standard exposure meter to the absorbed dose in the wall of a tissue-eq...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/25/2/002

    authors: Williams JR,Greening JR

    更新日期:1980-03-01 00:00:00

  • Simulational validation of color magnetic particle imaging (cMPI).

    abstract::Exploiting the field response of magnetic tracers, magnetic particle imaging (MPI) allows direct, local quantification of the tracer concentration in bulk structures. Here, we investigated the use of characteristic field response functions to spatially resolve the absolute concentration of multiple nanoparticle specie...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/21/6521

    authors: Han SH,Cho E,Lee DK,Cho G,Kim YR,Cho H

    更新日期:2014-11-07 00:00:00

  • Layer-specific ultrasound elastography using a multi-layered shear wave dispersion model for assessing the viscoelastic properties.

    abstract::Mechanical properties of biological tissues are significant biomarkers for diagnosing various diseases. Assessing the viscoelastic properties of multi-layer tissues has remained challenging for a long time. Some shear wave models have been proposed to estimate thin-layer tissues' viscoelasticity recently. However, the...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abca04

    authors: Lu G,Li R,Qian X,Chen R,Jiang L,Chen Z,Shung KK,Humayun MS,Zhou Q

    更新日期:2020-11-12 00:00:00

  • Evaluation of inverse methods and head models for EEG source localization using a human skull phantom.

    abstract::We used a real-skull phantom head to investigate the performances of representative methods for EEG source localization when considering various head models. We describe several experiments using a montage with current sources located at multiple positions and orientations inside a human skull filled with a conductive...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/46/1/306

    authors: Baillet S,Riera JJ,Marin G,Mangin JF,Aubert J,Garnero L

    更新日期:2001-01-01 00:00:00

  • Film dosimetry using a smart device camera: a feasibility study for point dose measurements.

    abstract::In this work, a methodology for using a smartphone camera, in conjunction with a light-tight box operating in reflective transmission mode, is investigated as a proof of concept for use as a film dosimetry system. An imaging system was designed to allow the camera of a smartphone to be used as a pseudo densitometer. T...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa8b36

    authors: Aland T,Jhala E,Kairn T,Trapp J

    更新日期:2017-10-03 00:00:00

  • Identifying critical human subpopulations by age groups: radioactivity and the lung.

    abstract::This work studies the effect of age on lung dose commitments arising from the inhalation of an atmosphere containing radionuclides of varying half-lives and physical sizes. This dependence is significant in many cases, approaching a ratio of 2 in several instances when the maximum dose at a given age is compared with ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/27/4/005

    authors: Crawford DJ

    更新日期:1982-04-01 00:00:00

  • Effect of electron contamination of a 6 MV x-ray beam on near surface diode dosimetry.

    abstract::In critical organ in vivo x-ray dosimetry, the relative contaminating electron contribution to the total dose and total detector response outside the field will be different to the corresponding contributions at the central axis detector calibration position, mainly due to the effects of shielding in the linear accele...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/24/013

    authors: Edwards CR,Mountford PJ,Moloney AJ

    更新日期:2006-12-21 00:00:00

  • LOR-interleaving image reconstruction for PET imaging with fractional-crystal collimation.

    abstract::Positron emission tomography (PET) has become an important modality in medical and molecular imaging. However, in most PET applications, the resolution is still mainly limited by the physical crystal sizes or the detector's intrinsic spatial resolution. To achieve images with better spatial resolution in a central reg...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/2/647

    authors: Li Y,Matej S,Karp JS,Metzler SD

    更新日期:2015-01-21 00:00:00

  • Trimmer sequencing time minimization during dynamically collimated proton therapy using a colony of cooperating agents.

    abstract::The dynamic collimation system (DCS) can be combined with pencil beam scanning proton therapy to deliver highly conformal treatment plans with unique collimation at each energy layer. This energy layer-specific collimation is accomplished through the synchronized motion of four trimmer blades that intercept the proton...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab416d

    authors: Smith BR,Hyer DE,Flynn RT,Hill PM,Culberson WS

    更新日期:2019-10-21 00:00:00

  • Accelerated time-of-flight (TOF) PET image reconstruction using TOF bin subsetization and TOF weighting matrix pre-computation.

    abstract::Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, there...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/3/1309

    authors: Mehranian A,Kotasidis F,Zaidi H

    更新日期:2016-02-07 00:00:00

  • Effect of microscopic modeling of skin in electrical and thermal analysis of transcranial direct current stimulation.

    abstract::Transcranial direct current stimulation (tDCS) is a neuromodulation scheme where a small current is delivered to the brain via two electrodes attached to the scalp. The electrode design is an important topic, not only as regards efficacy, but also from a safety perspective, as tDCS may be related to skin lesions that ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/61/24/8825

    authors: Gomez-Tames J,Sugiyama Y,Laakso I,Tanaka S,Koyama S,Sadato N,Hirata A

    更新日期:2016-12-21 00:00:00

  • Effects of body habitus on internal radiation dose calculations using the 5-year-old anthropomorphic male models.

    abstract::Computational phantoms are commonly used in internal radiation dosimetry to assess the amount and distribution pattern of energy deposited in various parts of the human body from different internal radiation sources. Radiation dose assessments are commonly performed on predetermined reference computational phantoms wh...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa75b4

    authors: Xie T,Kuster N,Zaidi H

    更新日期:2017-07-13 00:00:00

  • Generalized method for computation of true thickness and x-ray intensity information in highly blurred sub-millimeter bone features in clinical CT images.

    abstract::In clinical computed tomography (CT) images, cortical bone features with sub-millimeter (sub-mm) thickness are substantially blurred, such that their thickness is overestimated and their intensity appears underestimated. Therefore, any inquiry of the geometry or the density of such bones based on these images is sever...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/23/8099

    authors: Pakdel A,Robert N,Fialkov J,Maloul A,Whyne C

    更新日期:2012-12-07 00:00:00

  • Thresholds for visual detection of Young's modulus contrast in simulated ultrasound image movies.

    abstract::Elasticity imaging (EI) is being developed to allow the evaluation of the mechanical properties of soft tissue, but these properties are already assessed in routine ultrasound breast examination using a method that involves the subjective interpretation of tissue motion seen in real-time B-mode image movies during pal...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/45/8/301

    authors: Miller NR,Bamber JC

    更新日期:2000-08-01 00:00:00

  • Pre- and post-natal exposure of children to EMF generated by domestic induction cookers.

    abstract::Induction cookers are a type of cooking appliance that uses an intermediate-frequency magnetic field to heat the cooking vessel. The magnetic flux density produced by an induction cooker during operation was measured according to the EN 62233 standard, and the measured values were below the limits set in the standard....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/19/001

    authors: Kos B,Valič B,Miklavčič D,Kotnik T,Gajšek P

    更新日期:2011-10-07 00:00:00

  • A low-count reconstruction algorithm for Compton-based prompt gamma imaging.

    abstract::The Compton camera is an imaging device which has been proposed to detect prompt gammas (PGs) produced by proton-nuclear interactions within tissue during proton beam irradiation. Compton-based PG imaging has been developed to verify proton ranges because PG rays, particularly characteristic ones, have strong correlat...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aab737

    authors: Huang HM,Liu CC,Jan ML,Lee MW

    更新日期:2018-04-19 00:00:00

  • Aluminum equivalence of materials used in diagnostic radiology and its dependence on beam quality.

    abstract::A semi-empirical theory has been derived that relates the aluminum equivalence of various materials used in diagnostic radiology to their attenuation coefficients. The dependence of the aluminum hardness (AHE) and attenuation (AAE) equivalent on the beam quality is described in terms of effective energy. This 'aluminu...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/31/12/006

    authors: Nagel HD

    更新日期:1986-12-01 00:00:00

  • Application of the Monte Carlo integration (MCI) method for calculation of the anisotropy of 192Ir brachytherapy sources.

    abstract::Source anisotropy is a very important factor in the brachytherapy quality assurance of high-dose rate (HDR) 192Ir afterloading stepping sources. If anisotropy is not taken into account then doses received by a brachytherapy patient in certain directions can be in error by a clinically significant amount. Experimental ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/6/029

    authors: Baltas D,Giannouli S,Garbi A,Diakonos F,Geramani K,Ioannidis GT,Tsalpatouros A,Uzunoglu N,Kolotas C,Zamboglou N

    更新日期:1998-06-01 00:00:00

  • A neutron source with an effective energy of 0-5 keV.

    abstract::Calculations indicate that an assembly consisting of an antimony-beryllium source at the centre of a 4 cm radius water sphere surrounded by a 1 mm thick shell of boron-10 will emit neutrons with a broad spectrum at intermediate energies. A device based on this design was constructed using a water-filled, boron-carbide...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/21/1/007

    authors: Harvey JR,Bending RC

    更新日期:1976-01-01 00:00:00

  • Beam data measurements for dynamic wedges on Varian 600C (6 MV) and 2100C (6 and 10 MV) linear accelerators.

    abstract::The measurement of beam data for dynamic wedge dosimetry requires the integration of radiation dose at points across the radiation field during the dose delivery. The different measurement techniques required when using a linear diode array to measure beam profiles and when using ionization chambers to measure depth d...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/40/3/005

    authors: Bidmead AM,Garton AJ,Childs PJ

    更新日期:1995-03-01 00:00:00

  • Intraoperative evaluation of device placement in spine surgery using known-component 3D-2D image registration.

    abstract::Intraoperative x-ray radiography/fluoroscopy is commonly used to assess the placement of surgical devices in the operating room (e.g. spine pedicle screws), but qualitative interpretation can fail to reliably detect suboptimal delivery and/or breach of adjacent critical structures. We present a 3D-2D image registratio...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa62c5

    authors: Uneri A,De Silva T,Goerres J,Jacobson MW,Ketcha MD,Reaungamornrat S,Kleinszig G,Vogt S,Khanna AJ,Osgood GM,Wolinsky JP,Siewerdsen JH

    更新日期:2017-04-21 00:00:00

  • Simulation of voltage-sensitive optical signals in three-dimensional slabs of cardiac tissue: application to transillumination and coaxial imaging methods.

    abstract::Voltage-sensitive dyes are an important tool in visualizing electrical activity in cardiac tissue. Until today, they have mainly been applied in cardiac electrophysiology to subsurface imaging. In the present study, we assess different imaging methods used in optical tomography with respect to their effectiveness in v...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/2/003

    authors: Bernus O,Wellner M,Mironov SF,Pertsov AM

    更新日期:2005-01-21 00:00:00

  • Modeling late rectal toxicities based on a parameterized representation of the 3D dose distribution.

    abstract::Many models exist for predicting toxicities based on dose-volume histograms (DVHs) or dose-surface histograms (DSHs). This approach has several drawbacks as firstly the reduction of the dose distribution to a histogram results in the loss of spatial information and secondly the bins of the histograms are highly correl...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/7/013

    authors: Buettner F,Gulliford SL,Webb S,Partridge M

    更新日期:2011-04-07 00:00:00

  • Magnetic resonance electrical property mapping at 21.1 T: a study of conductivity and permittivity in phantoms, ex vivo tissue and in vivo ischemia.

    abstract::Electrical properties (EP), namely conductivity and permittivity, can provide endogenous contrast for tissue characterization. Using electrical property tomography (EPT), maps of EP can be generated from conventional MRI data. This report investigates the feasibility and accuracy of EPT at 21.1 T for multiple RF coils...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab3259

    authors: Amouzandeh G,Mentink-Vigier F,Helsper S,Bagdasarian FA,Rosenberg JT,Grant SC

    更新日期:2020-02-28 00:00:00

  • The unique determination of the primary current by MEG and EEG.

    abstract::In this paper, we use a more realistic head model with ovoid geometry for approximation of a human head. By inverting the Geselowitz equation, some analytic results on the inverse MEG problem are presented in homogenous ovoid geometry. On one hand, some information about the components of primary current is shown by t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/21/012

    authors: Peng L,Cheng J,Jin L

    更新日期:2006-11-07 00:00:00

  • Accounting for range uncertainties in the optimization of intensity modulated proton therapy.

    abstract::Treatment plans optimized for intensity modulated proton therapy (IMPT) may be sensitive to range variations. The dose distribution may deteriorate substantially when the actual range of a pencil beam does not match the assumed range. We present two treatment planning concepts for IMPT which incorporate range uncertai...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/10/009

    authors: Unkelbach J,Chan TC,Bortfeld T

    更新日期:2007-05-21 00:00:00