Aluminum equivalence of materials used in diagnostic radiology and its dependence on beam quality.

abstract：:Respiratory-correlated cone-beam CT (CBCT) not only inhibits rapid scanning due to the slow speed of the LINAC head gantry rotation, but its implementation for routine patient imaging is impractical because of the high radiation dose delivered during the process. Digital tomosynthesis (DTS) is a potentially faster tec...

journal_title：Physics in medicine and biology

authors： Choi S,Lee S,Kang YN,Hsieh SS,Kim HJ

更新日期：2019-05-02 00:00:00

abstract：:In this study, we evaluate the feasibility of designing a beveled fiber-optic probe coupled with a ball lens for improving depth-resolved fluorescence measurements of epithelial tissue using Monte Carlo (MC) simulations. The results show that by using the probe configuration with a beveled tip collection fiber and a f...

journal_title：Physics in medicine and biology

authors： Jaillon F,Zheng W,Huang Z

更新日期：2008-02-21 00:00:00

abstract：:The aim of the study is to assess the staging value of the tumor heterogeneity characterized by texture features and other commonly used semi-quantitative indices extracted from (18)F-FDG PET images of cervical cancer (CC) patients. Forty-two patients suffering CC at different stages were enrolled in this study. First...

journal_title：Physics in medicine and biology

authors： Mu W,Chen Z,Liang Y,Shen W,Yang F,Dai R,Wu N,Tian J

更新日期：2015-07-07 00:00:00

abstract：:An inflatable endorectal balloon (ERB) is often used during stereotactic body radiation therapy (SBRT) for treatment of prostate cancer in order to reduce both intrafraction motion of the target and risk of rectal toxicity. However, the ERB can exert significant force on the prostate, and this work assessed the impact...

journal_title：Physics in medicine and biology

authors： Jones BL,Gan G,Kavanagh B,Miften M

更新日期：2013-11-21 00:00:00

abstract：:The Hug-Kellerer (H-K) equation is one of the earliest proposed radiation cell survival curves. We examine this equation in view of the recent perceived need for a universal cell survival curve which would be applicable to single radiation fractions at high doses. We derive relationships between the three parameters o...

journal_title：Physics in medicine and biology

authors： Ekstrand KE

更新日期：2010-05-21 00:00:00

abstract：:Wafer-scale CMOS active pixel sensors (APSs) have been developed recently for x-ray imaging applications. The small pixel pitch and low noise are very promising properties for medical imaging applications such as digital breast tomosynthesis (DBT). In this work, we evaluated experimentally and through modeling the ima...

journal_title：Physics in medicine and biology

authors： Zhao C,Konstantinidis AC,Zheng Y,Anaxagoras T,Speller RD,Kanicki J

更新日期：2015-12-07 00:00:00

abstract：:Simultaneous dual-radionuclide myocardial perfusion/innervation SPECT imaging can provide important information about the mismatch between scar tissue and denervated regions. The Siemens IQ-SPECT system developed for cardiac imaging uses a multifocal SMARTZOOM collimator to achieve a four-fold sensitivity for the card...

journal_title：Physics in medicine and biology

authors： Du Y,Bhattacharya M,Frey EC

更新日期：2014-06-07 00:00:00

abstract：:In this work, a methodology for using a smartphone camera, in conjunction with a light-tight box operating in reflective transmission mode, is investigated as a proof of concept for use as a film dosimetry system. An imaging system was designed to allow the camera of a smartphone to be used as a pseudo densitometer. T...

journal_title：Physics in medicine and biology

authors： Aland T,Jhala E,Kairn T,Trapp J

更新日期：2017-10-03 00:00:00

abstract：:A method for registering images acquired from a prototype flat panel mobile C-arm, capable of kilovoltage (kV) cone-beam computed tomography (CT), to a linear accelerator (LINAC) isocenter is presented. A calibration procedure is performed which involves locating reflective markers placed on the C-arm and a phantom in...

journal_title：Physics in medicine and biology

authors： Sorensen S,Mitschke M,Solberg T

更新日期：2007-06-21 00:00:00

abstract：:The feasibility is demonstrated of a numerical method to calculate dose deposition by broad high-energy electron beams in homogeneous matter or in heterogeneous matter in which the heterogeneities are arranged in slabs perpendicular to the beam axis. The method is based only on the basic physical interaction processes...

journal_title：Physics in medicine and biology

authors： Huizenga H,Storchi PR

更新日期：1989-10-01 00:00:00

abstract：:Diffraction-enhanced imaging (DEI) is an analyser-based x-ray imaging method that produces separate images depicting the projected x-ray absorption and refractive properties of an object. Because the imaging model of DEI does not account for ultra-small-angle x-ray scattering (USAXS), the images produced in DEI can co...

journal_title：Physics in medicine and biology

authors： Chou CY,Anastasio MA,Brankov JG,Wernick MN,Brey EM,Connor DM,Zhong Z

更新日期：2007-04-07 00:00:00

abstract：:The probability of a photon (x-ray, gamma-ray, bremsstrahlung, etc) of a given energy E undergoing absorption or scattering when traversing a layer of material Z can be expressed quantitatively in terms of a linear attenuation coefficient mu (cm(-1)). Since mu is dependent on the material's density, rho (g cm(-3)), wh...

journal_title：Physics in medicine and biology

authors： Hubbell JH

更新日期：1999-01-01 00:00:00

abstract：:Histotripsy is a therapeutic ultrasound modality under development to liquefy tissue mechanically via bubble clouds. Image guidance of histotripsy requires both quantification of the bubble cloud activity and accurate delineation of the treatment zone. In this study, magnetic resonance (MR) and diagnostic ultrasound i...

journal_title：Physics in medicine and biology

authors： Anthony GJ,Bollen V,Hendley S,Antic T,Sammet S,Bader KB

更新日期：2019-05-02 00:00:00

abstract：:Computational simulations, such as Monte Carlo track structure simulations, offer a powerful tool for quantitatively investigating radiation interactions within cells. The modelling of the spatial distribution of energy deposition events as well as diffusion of chemical free radical species, within realistic biologica...

journal_title：Physics in medicine and biology

authors： McNamara AL,Ramos-Méndez J,Perl J,Held K,Dominguez N,Moreno E,Henthorn NT,Kirkby KJ,Meylan S,Villagrasa C,Incerti S,Faddegon B,Paganetti H,Schuemann J

更新日期：2018-09-06 00:00:00

abstract：:Magnetic particle imaging is a new approach to visualizing magnetic nanoparticles. It is capable of 3D real-time in vivo imaging of particles injected into the blood stream and is a candidate for medical imaging applications. To date, only one particle type has been imaged at a time, however, the ability to separate s...

journal_title：Physics in medicine and biology

authors： Rahmer J,Halkola A,Gleich B,Schmale I,Borgert J

更新日期：2015-03-07 00:00:00

abstract：:Droplets of liquid perfluorocarbon (PFC) are under study as the next generation of contrast agents for ultrasound (US). These droplets can be selectively vaporized into echogenic gas bubbles in situ by externally applied US, with numerous applications to diagnosis and therapy. However, little is known about the mechan...

journal_title：Physics in medicine and biology

authors： Reznik N,Seo M,Williams R,Bolewska-Pedyczak E,Lee M,Matsuura N,Gariepy J,Foster FS,Burns PN

更新日期：2012-11-07 00:00:00

abstract：:Compact gamma cameras with a square-shaped monolithic scintillator crystal and an array of silicon photomultipliers (SiPMs) are actively being developed for applications in areas such as small animal imaging, cancer diagnostics and radiotracer guided surgery. Statistical methods of position reconstruction, which are p...

journal_title：Physics in medicine and biology

authors： Morozov A,Alves F,Marcos J,Martins R,Pereira L,Solovov V,Chepel V

更新日期：2017-05-07 00:00:00

abstract：:In this paper we present a novel method of reducing the dosimetric effects of the finite leaf width of a multileaf collimator (MLC) in conformal and intensity modulated radiotherapy (IMRT). This is achieved by decomposing the required high-resolution fluence distribution into two orthogonal components, which are deliv...

journal_title：Physics in medicine and biology

authors： Evans PM,Partridge M

更新日期：2000-03-01 00:00:00

abstract：:New organ dose conversion coefficients for coronary angiographic interventions are presented, as well as dose distributions and resulting maximal local dose conversion coefficients in the relevant organs. For the Monte Carlo based simulations, voxel models of the human anatomy were employed which represent the average...

journal_title：Physics in medicine and biology

authors： Schlattl H,Zankl M,Hausleiter J,Hoeschen C

更新日期：2007-08-07 00:00:00

abstract：:The relative stopping power (RSP) uncertainty is the largest contributor to the range uncertainty in proton therapy. The purpose of this work was to develop a systematic method that yields accurate and patient-specific RSPs by combining (1) pre-treatment x-ray CT and (2) daily proton radiography of the patient. The me...

journal_title：Physics in medicine and biology

authors： Collins-Fekete CA,Brousmiche S,Hansen DC,Beaulieu L,Seco J

更新日期：2017-08-03 00:00:00

abstract：:Proton therapy with active scanning beam delivery has significant advantages compared to conventional radiotherapy. However, so far only static targets have been treated in this way, since moving targets potentially lead to interplay effects. For 4D treatment planning, information on the target motion is needed to cal...

journal_title：Physics in medicine and biology

authors： Zhang Y,Boye D,Tanner C,Lomax AJ,Knopf A

更新日期：2012-04-07 00:00:00

abstract：:EEG recordings made in combined EEG-fMRI studies are corrupted by gradient artefacts (GAs) resulting from the interaction of the EEG system with the time-varying magnetic field gradients used in MRI. The dominant contribution to the GA arises from interaction with the leads of the EEG cap and the human head, but artef...

journal_title：Physics in medicine and biology

authors： Chowdhury ME,Mullinger KJ,Bowtell R

更新日期：2015-06-21 00:00:00

abstract：:This study investigated the temperature elevation in the eye of anatomically based human head models for plane-wave exposures. The finite-difference time-domain method is used for analyzing electromagnetic absorption and temperature elevation. The eyes in the anatomic models have average dimensions and weight. Computa...

journal_title：Physics in medicine and biology

authors： Hirata A,Watanabe S,Fujiwara O,Kojima M,Sasaki K,Shiozawa T

更新日期：2007-11-07 00:00:00

abstract：:Fractional flow reserve (FFR) provides an objective physiological evaluation of stenosis severity. A technique that can measure FFR using only angiographic images would be a valuable tool in the cardiac catheterization laboratory. To perform this, the diseased blood flow can be measured with a first pass distribution ...

journal_title：Physics in medicine and biology

authors： Wong JT,Molloi S

更新日期：2008-07-21 00:00:00

abstract：:A common dose-saving technique used in modern CT devices is automatic tube current modulation (TCM), which was originally designed to also reduce the dose in paediatric CT patients. In order to be able to deduce detailed organ doses of paediatric models, dose conversion coefficients normalized to CTDI(vol) for an eigh...

journal_title：Physics in medicine and biology

authors： Schlattl H,Zankl M,Becker J,Hoeschen C

更新日期：2012-10-21 00:00:00

abstract：:The aim of the study is to verify the fundamental assumption in the monitor source method, i.e. uniform fractional count loss across the field of view (FOV), and to introduce a revised monitor source method for SPECT deadtime correction that minimally interferes with the clinical protocol. SPECT images of non-uniform ...

journal_title：Physics in medicine and biology

authors： Siman W,Silosky M,Kappadath SC

更新日期：2015-02-07 00:00:00

abstract：:Depth-dose distributions were calculated for thermal and epithermal neutron fluence and capture gamma ray dose rates using a two-dimensional neutron-coupled gamma-ray transport code (DOT 3.5) for gadolinium neutron capture therapy. The results show that (i) a capture gamma-ray dose rate of 10 Gy h-1 was obtained with ...

journal_title：Physics in medicine and biology

authors： Matsumoto T

更新日期：1992-01-01 00:00:00

abstract：:Instead of performing a numerical deconvolution, we propose to use a linear piecewise-continuous model of the renal impulse response function for parametric fitting of renal scintigraphy data, to obtain clinically useful renal parameters. The strengths of the present model are its simplicity and speed of computation, ...

journal_title：Physics in medicine and biology

authors： Zhang JL,Zhang L,Koh TS,Shuter B

更新日期：2003-06-21 00:00:00

abstract：:In addition to being a powerful clinical tool, Positron emission tomography (PET) is also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. However, dosi...

journal_title：Physics in medicine and biology

authors： Xie T,Zaidi H

更新日期：2013-01-07 00:00:00

abstract：:Recently, the initial 2D physical characterization of a small-diameter positron emission tomograph, designed specifically for scanning of small laboratory animals, was reported. The physical characteristics of the tomograph operating in 3D mode have now been measured and compared to those obtained in 2D mode. In 3D, t...

journal_title：Physics in medicine and biology

authors： Bloomfield PM,Myers R,Hume SP,Spinks TJ,Lammertsma AA,Jones T

更新日期：1997-02-01 00:00:00