Minoxidil in patients with chronic left heart failure: contrasting hemodynamic and clinical effects in a controlled trial.

abstract：:This study describes the efficacy of the right gastroepiploic artery (GEA) as graft material for coronary artery bypass grafting (CABG) as assessed by exercise thallium 201 myocardial scintigraphy in eight patients (age, 59.4 +/- 9.35 years [mean +/- SD]) who underwent CABG with the GEA graft in the past 2 years. Plan...

journal_title：Circulation

authors： Kusukawa J,Hirota Y,Kawamura K,Suma H,Takeuchi A,Adachi I,Akagi H

更新日期：1989-09-01 00:00:00

abstract：:The effects of therapeutic levels of quinidine were studied in an ischemic gap preparation of reflected reentry. The preparation consisted of a Purkinje fiber mounted in a three-compartment chamber. A narrow central compartment was perfused with a solution prepared to mimic the extracellular milieu at a site of ischem...

journal_title：Circulation

authors： Shen XT,Antzelevitch C

更新日期：1986-06-01 00:00:00

abstract：:Endocardial catheter mapping was performed in 15 patients in sinus rhythm who had no evidence of structural heart disease and normal left ventricles. Mapping was performed with the use of 10 mm interelectrode distance from various left ventricular endocardial sites. In 10 patients a quantitative analysis of electrogra...

journal_title：Circulation

authors： Cassidy DM,Vassallo JA,Marchlinski FE,Buxton AE,Untereker WJ,Josephson ME

更新日期：1984-07-01 00:00:00

abstract：:Volume loading is used to treat hemodynamically compromised patients with acute pulmonary embolism despite data to suggest that volume loading after embolism might cause a leftward shift of the ventricular septum with a subsequent decrease in left ventricular (LV) end-diastolic volume and stroke work. We studied 10 cl...

journal_title：Circulation

authors： Belenkie I,Dani R,Smith ER,Tyberg JV

更新日期：1989-07-01 00:00:00

abstract：:The amplitude and distribution of epicardial ST-segment elevation (ST) were examined for an 8-hour period after coronary occlusion in eight baboons and five pigs. ST was determined from unipolar epicardial electrograms obtained from a high-resolution matrix of fixed electrodes overlying a transmural region of ischemia...

journal_title：Circulation

authors： Smith GT,Geary G,Ruf W,Roelofs TH,McNamara JJ

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Most survival prediction models for coronary artery bypass grafting surgery are limited to in-hospital or 30-day end points. We estimate a long-term survival model using data from the Society of Thoracic Surgeons Adult Cardiac Surgery Database and Centers for Medicare and Medicaid Services. METHODS AND RESU...

journal_title：Circulation

authors： Shahian DM,O'Brien SM,Sheng S,Grover FL,Mayer JE,Jacobs JP,Weiss JM,Delong ER,Peterson ED,Weintraub WS,Grau-Sepulveda MV,Klein LW,Shaw RE,Garratt KN,Moussa ID,Shewan CM,Dangas GD,Edwards FH

更新日期：2012-03-27 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) after cardiac surgery is associated with increased risk of complications, length of stay, and cost of care. Observational evidence suggests that patients who have undergone previous statin therapy have a lower incidence of postoperative AF. We tested this observation in a randomized,...

journal_title：Circulation

authors： Patti G,Chello M,Candura D,Pasceri V,D'Ambrosio A,Covino E,Di Sciascio G

更新日期：2006-10-03 00:00:00

abstract：:Esophageal perforation is a dreaded complication of atrial fibrillation ablation that occurs in 0.1% to 0.25% of atrial fibrillation ablation procedures. Delayed diagnosis is associated with the development of atrial-esophageal fistula (AEF) and increased mortality. The relationship between the esophagus and the left ...

journal_title：Circulation

authors： Kapur S,Barbhaiya C,Deneke T,Michaud GF

更新日期：2017-09-26 00:00:00

abstract：:The ability of predischarge quantitative exercise thallium-201 (201T1) scintigraphy to predict future cardiac events was evaluated prospectively in 140 consecutive patients with uncomplicated acute myocardial infarction; the results were compared with those of submaximal exercise treadmill testing and coronary angiogr...

journal_title：Circulation

authors： Gibson RS,Watson DD,Craddock GB,Crampton RS,Kaiser DL,Denny MJ,Beller GA

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:The associations between pregnancy hypertensive disorders and common cardiovascular disorders have not been investigated at scale in a contemporaneous population. We aimed to investigate the association between preeclampsia, hypertensive disorders of pregnancy, and subsequent diagnosis of 12 different cardio...

journal_title：Circulation

authors： Leon LJ,McCarthy FP,Direk K,Gonzalez-Izquierdo A,Prieto-Merino D,Casas JP,Chappell L

更新日期：2019-09-24 00:00:00

abstract：BACKGROUND:Endothelium-derived nitric oxide is an important modulator of resting vascular tone in animals and humans. However, the contribution of nitric oxide to exercise-induced vasodilation is unknown. METHODS AND RESULTS:The effect of NG-monomethyl-L-arginine (L-NMMA), an inhibitor of nitric oxide synthesis, on ex...

journal_title：Circulation

authors： Gilligan DM,Panza JA,Kilcoyne CM,Waclawiw MA,Casino PR,Quyyumi AA

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Two sequential biphasic shocks delivered over separate lead configurations markedly improve defibrillation efficacy compared with a single shock alone. We investigated the effect of varying the intershock interval between sequential biphasic shocks on defibrillation. METHODS AND RESULTS:Defibrillation thres...

journal_title：Circulation

authors： Johnson EE,Alferness CA,Wolf PD,Smith WM,Ideker RE

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Current two-dimensional echocardiographic measures of right ventricular volume are limited by the asymmetrical and crescentic shape of the ventricle and by difficulty in obtaining standardized views. Three-dimensional echocardiographic reconstruction, which does not require geometric assumptions or standardi...

journal_title：Circulation

authors： Jiang L,Siu SC,Handschumacher MD,Luis Guererro J,Vazquez de Prada JA,King ME,Picard MH,Weyman AE,Levine RA

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Convincing evidence suggests that atherosclerosis is an inflammatory disease. The inflammatory response is an important determinant of atherosclerotic plaque instability. Therefore, we investigated the prognostic impact of key inflammatory players, namely the inflammatory marker C-reactive protein (CRP) and ...

journal_title：Circulation

authors： Heeschen C,Dimmeler S,Hamm CW,Fichtlscherer S,Boersma E,Simoons ML,Zeiher AM,CAPTURE Study Investigators.

更新日期：2003-04-29 00:00:00

abstract：BACKGROUND:Exertional fatigue, which frequently limits exercise in patients with chronic heart failure, is associated with early anaerobic metabolism in skeletal muscle. The present study was designed to examine the skeletal muscle metabolic response to exercise in this disorder and determine the relation of reduced mu...

journal_title：Circulation

authors： Sullivan MJ,Green HJ,Cobb FR

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Sympathetic activation and respiratory abnormalities may each be implicated in the pathophysiology of congestive heart failure (CHF). Chemoreflexes are an important mechanism regulating both sympathetic drive and breathing. We therefore tested the hypothesis that chemoreflex function is altered in CHF. METH...

journal_title：Circulation

authors： Narkiewicz K,Pesek CA,van de Borne PJ,Kato M,Somers VK

更新日期：1999-07-20 00:00:00

abstract：:Hemodynamic effects of dobutamine and dopamine (both 5, 10, 15 microgram/kg/min) and epinephrine (0.04 microgram/kg/min) were studied immediately following cessation of cardiopulmonary bypass in 34 patients with preoperative evidence of left ventricular dysfunction. Significant increases in mean cardiac index were see...

journal_title：Circulation

authors： Steen PA,Tinker JH,Pluth JR,Barnh;rst DA,Tarhan S

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:The cellular content of cAMP generated by activation of adenylylcyclase (AC) through the beta-adrenergic receptor (betaAR) is a key determinant of a cell's response to catecholamine stimulation. We tested the hypothesis that increased AC content, independently of betaAR number, increases responsiveness to ca...

journal_title：Circulation

authors： Gao MH,Lai NC,Roth DM,Zhou J,Zhu J,Anzai T,Dalton N,Hammond HK

更新日期：1999-03-30 00:00:00

abstract：BACKGROUND:Current studies have demonstrated that applying therapeutic hypothermia for 12 to 24 hours after resuscitation from cardiac arrest improves the outcomes of cardiopulmonary resuscitation. The present study investigated whether a shorter duration of therapeutic hypothermia induced quickly and early after resus...

journal_title：Circulation

authors： Ye S,Weng Y,Sun S,Chen W,Wu X,Li Z,Weil MH,Tang W

更新日期：2012-01-03 00:00:00

abstract：BACKGROUND:Ventricular tachyarrhythmias present a unique set of stimuli to arterial and cardiopulmonary baroreceptors by increasing cardiac filling pressures and decreasing arterial pressure. The net effect on the control of sympathetic nerve activity (SNA) in humans is unknown. The purpose of this study was to determi...

journal_title：Circulation

authors： Smith ML,Joglar JA,Wasmund SL,Carlson MD,Welch PJ,Hamdan MH,Quan K,Page RL

更新日期：1999-08-10 00:00:00

abstract：BACKGROUND:Enteroviridae such as coxsackievirus B3 (CVB3) are important infectious agents involved in viral heart disease, hepatitis, and pancreatitis, but no specific antiviral therapy is available. METHODS AND RESULTS:The aim of the present study was to evaluate the impact of RNA interference on viral replication, c...

journal_title：Circulation

authors： Merl S,Michaelis C,Jaschke B,Vorpahl M,Seidl S,Wessely R

更新日期：2005-04-05 00:00:00

abstract：BACKGROUND:Oxidized LDLs (oxLDLs) and matrix metalloproteinases (MMPs) are present in atherosclerotic lesions. OxLDLs activate various signaling pathways potentially involved in atherogenesis. OxLDLs induce smooth muscle cell (SMC) proliferation mediated by the activation of the sphingomyelin/ceramide pathway and tyros...

journal_title：Circulation

authors： Augé N,Maupas-Schwalm F,Elbaz M,Thiers JC,Waysbort A,Itohara S,Krell HW,Salvayre R,Nègre-Salvayre A

更新日期：2004-08-03 00:00:00

abstract：BACKGROUND:approximately half of patients with heart failure die suddenly as a result of ventricular arrhythmias. Although abnormal Ca(2+) release from the sarcoplasmic reticulum through ryanodine receptors (RyR2) has been linked to arrhythmogenesis, the molecular mechanisms triggering release of arrhythmogenic Ca(2+) ...

journal_title：Circulation

authors： van Oort RJ,McCauley MD,Dixit SS,Pereira L,Yang Y,Respress JL,Wang Q,De Almeida AC,Skapura DG,Anderson ME,Bers DM,Wehrens XH

更新日期：2010-12-21 00:00:00

abstract：BACKGROUND:Long-term implantable left ventricular assist devices (LVADs) are increasingly used as a bridge to cardiac transplantation and may be used as long-term therapy for end-stage heart failure. After insertion of an LVAD, patients frequently become ambulatory. Sensors contained within these devices can measure th...

journal_title：Circulation

authors： Foray A,Williams D,Reemtsma K,Oz M,Mancini D

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:The time constant of ventricular relaxation (tau) is a quantitative measure of diastolic performance requiring intraventricular pressure recording. This study validates in humans an equation relating tau to left ventricular pressure at peak -dP/dt (P0), pressure at mitral valve opening (PMV), and isovolumic ...

journal_title：Circulation

authors： Scalia GM,Greenberg NL,McCarthy PM,Thomas JD,Vandervoort PM

更新日期：1997-01-07 00:00:00

abstract：BACKGROUND:Chlamydia pneumoniae (Cp) has been demonstrated in arteries and abdominal aortic aneurysms (AAAs). However, the validity of the methods used is questioned, and antibiotic treatment trials have thus far shown disappointing results. Nevertheless, antibodies against the Cp outer membrane proteins (OMPs) have be...

journal_title：Circulation

authors： Lindholt JS,Støvring J,Østergaard L,Urbonavicius S,Henneberg EW,Honoré B,Vorum H

更新日期：2004-05-04 00:00:00

abstract：BACKGROUND:Microvascular dysfunction in hypertrophic cardiomyopathy (HCM) may create an ischemic substrate conducive to sudden death, but it remains unknown whether the extent of hypertrophy is associated with proportionally poorer perfusion reserve. Comparisons between magnitude of hypertrophy, impairment of perfusion...

journal_title：Circulation

authors： Petersen SE,Jerosch-Herold M,Hudsmith LE,Robson MD,Francis JM,Doll HA,Selvanayagam JB,Neubauer S,Watkins H

更新日期：2007-05-08 00:00:00

abstract：BACKGROUND:Atrial fibrillation is associated with increased risks of death, stroke/systemic embolism, and bleeding (incurred by antithrombotic therapy), which may occur early after diagnosis. METHODS:We assessed the risk of early events (death, stroke/systemic embolism, and major bleeding) over 12 months and their rel...

journal_title：Circulation

authors： Bassand JP,Virdone S,Goldhaber SZ,Camm AJ,Fitzmaurice DA,Fox KAA,Goto S,Haas S,Hacke W,Kayani G,Mantovani LG,Misselwitz F,Pieper KS,Turpie AGG,van Eickels M,Verheugt FWA,Kakkar AK

更新日期：2019-02-05 00:00:00

abstract：BACKGROUND:In the experimental setting, it has been demonstrated that preconditioning myocardium before prolonged occlusion with brief ischemic episodes affords substantial protection to the cells by delaying lethal injury, thereby limiting infarct size. Whether the same occurs in humans remains unknown. METHODS AND R...

journal_title：Circulation

authors： Ottani F,Galvani M,Ferrini D,Sorbello F,Limonetti P,Pantoli D,Rusticali F

更新日期：1995-01-15 00:00:00

abstract：:Ventricular septal defects are the most common congenital heart defect. They vary greatly in location, clinical presentation, associated lesions, and natural history. The present article describes the clinical aspects of ventricular septal defects and current management strategies. ...

journal_title：Circulation

authors： Minette MS,Sahn DJ

更新日期：2006-11-14 00:00:00