Abstract:
:Cefotaxime, a third generation cephalosporin antibiotic, was evaluated in 26 infants and children for the treatment of documented or suspected bacterial infections, including pneumonia (10 cases), soft tissue skin infection (13 cases), and urinary tract infection (3 cases). An average daily dose of 60 mg/kg in 3 to 4 divided doses was administered parenterally for an average of 7 days. In 14 of the cases, primary pathogens, including Haemophilus influenzae b (resistant to ampicillin), Staphylococcus aureus, Staphylococcus pyogenes, Streptococcus pneumoniae and Escherichia coli, were eradicated. Clinical recovery occurred in each case. Blood levels at different time intervals and biological half-life were similar to those reported for adults. Mild and transient side effects observed were elevation of SGOT in two cases, alkaline phosphatase in one, and eosinophilia in one case.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Varghese M,Khan AJ,Kumar K,Schaeffer HA,Pierro M,Evans HEdoi
10.1177/000992288402300406subject
Has Abstractpub_date
1984-04-01 00:00:00pages
220-2issue
4eissn
0009-9228issn
1938-2707journal_volume
23pub_type
杂志文章abstract::Serum IgG, IgM, and IgA were measured in 316 infants younger than 12 months of age. Information including the child's race, sex, age, and past history of infections or atopy was collected. Birth records were also reviewed to ascertain the child's birthweight and gestational age. Serum IgG levels were higher in black i...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502400204
更新日期:1985-02-01 00:00:00
abstract::Over-the-counter cold remedies are widely used for symptomatic relief of upper respiratory tract infections. The safety of these drugs is not well established in infants and their efficacy is questionable. Our aim was to study the attitude of family physicians and pediatricians toward the use of cold remedies in infan...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922806295281
更新日期:2006-11-01 00:00:00
abstract::A 6-year-old girl with sickle cell disease was admitted to the hospital with the diagnosis of the acute chest syndrome. The laboratory findings and the radionuclear lung scan supported a diagnosis of pulmonary infarction rather than pneumonia. She improved with intravenous fluids, oxygen, penicillin, and theophylline....
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502401209
更新日期:1985-12-01 00:00:00
abstract::Headache is a highly prevalent condition and is the leading cause for school absences. Despite the rich literature supporting behavioral treatments for headache, many child psychologists mistakenly perceive that they lack appropriate training to treat children with headache. Likewise, many physicians feel underprepare...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922816638665
更新日期:2017-01-01 00:00:00
abstract::Transient cataracts in patients with insulin-dependent diabetes mellitus (IDDM) are rare and have been reported only in association with severe ketoacidosis or hyperosmolarity. We present an adolescent with transient bilateral posterior subcapsular cataracts, which developed after the recent onset of IDDM without keto...
journal_title:Clinical pediatrics
pub_type: 信件
doi:10.1177/000992289303201108
更新日期:1993-11-01 00:00:00
abstract::The effects of position (upright vs reclining) and support (held vs chair) on the development and maintenance of feeding behavior were examined in a child with bronchopulmonary dysplasia and gastroesophageal reflux. A reclining position initially facilitated acceptance and swallowing with relatively rapid generalizati...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289403300102
更新日期:1994-01-01 00:00:00
abstract::The Internet, an extensive network of interlinked computers storing immense quantities of information, is growing exponentially. The author was interested in discovering what sources of information exist on this network that might be of importance to the pediatric health care provider. To accomplish this aim, a litera...
journal_title:Clinical pediatrics
pub_type: 历史文章,杂志文章,评审
doi:10.1177/000992289603500501
更新日期:1996-05-01 00:00:00
abstract::Families of children voluntarily enrolled in a managed care program for children with special health care needs receiving SSI and Medicaid benefits and their case managers were surveyed regarding care satisfaction, quality, and access. Claims data were used to compare the cost and utilization of health care before and...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289903800305
更新日期:1999-03-01 00:00:00
abstract::In this retrospective case series, we report clinical factors associated with pediatric peritonsillar abscess (PTA), with hopes of contributing to the design of an evidenced-based, economic treatment approach. Charts were examined for presenting symptoms and signs. Each of these were analyzed for association with the ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922818778048
更新日期:2018-10-01 00:00:00
abstract::Eighty children with acute otitis media (AOM) were prospectively studied to determine the correlation and clinical usefulness of nasopharyngeal (NP), conjunctival (CONJ), and middle ear fluid (MEF) cultures. NP cultures correlated more accurately with MEF (p less than 0.01) than did CONJ cultures (p less than 0.05) fo...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500205
更新日期:1986-02-01 00:00:00
abstract::More than 300 patients who presented consecutively to a sexual abuse clinic, a family planning clinic, and a family practice clinic filled out an anonymous survey regarding unwanted sexual experiences. In the family planning and family practice clinics, 40% of females and 16% of males reported having at least one unwa...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1177/000992289503400603
更新日期:1995-06-01 00:00:00
abstract::An asymptomatic child with a murmur can be challenging practice management conundrum. Some providers refer all patients with a "new" murmur to a cardiologist, likely resulting in excessive resource utilization and parental anxiety. This study examines whether the prevalence of significant cardiac pathology differs in ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922816656623
更新日期:2017-04-01 00:00:00
abstract::Premature delivery is common in pregnancies complicated by maternal diabetes. However, the outcome of very-low-birth-weight infants (VLBWI) born to mothers with diabetes is not known. Employing a matched double-cohort design, we investigated the influence of maternal diabetes on the outcome of VLBWI born in Winnipeg f...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280204100705
更新日期:2002-09-01 00:00:00
abstract::Dextromethorphan hydrobromide (DXM), a constituent of more than 125 patent cough/cold remedies, is the most popular antitussive medication in the United States. Cough syrups or capsules also contain additional ingredients such as acetaminophen, chlorpheniramine maleate, guaifenesin, and/or pseudoephedrine, and toxicit...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992280504400702
更新日期:2005-09-01 00:00:00
abstract::Pediatricians and family physicians can play a significant role in the initiation of dental care for preschool children because they are seen more often by a physician than a dentist. The Committee on Standards for Child Health Care of the American Academy of Pediatrics recommends inspection of the mouth, teeth, and g...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500705
更新日期:1986-07-01 00:00:00
abstract::Prior studies have found that close mother-child sleep proximity helps increase rates of breastfeeding, and breastfeeding itself is linked to better maternal and infant health. In this study, we examine whether breastfeeding and infant bed-sharing are related to daily rhythms of the stress-responsive hormone cortisol....
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815601981
更新日期:2016-05-01 00:00:00
abstract::Sleep-disordered breathing (SDB) is prevalent in children and most commonly treated by surgery with adenotonsillectomy. We aimed to learn physician perspectives of social and communication factors that influence decision making for treatment of pediatric SDB. Purposive sampling identified 10 physician key informants a...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922817702939
更新日期:2017-10-01 00:00:00
abstract::Half of US school children receive influenza vaccine. In our previous trials, school-located influenza vaccination (SLIV) raised vaccination rates by 5 to 8 percentage points. We assessed whether text message reminders to parents could raise vaccination rates above those observed with SLIV. Within urban elementary sch...
journal_title:Clinical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1177/0009922818821878
更新日期:2019-04-01 00:00:00
abstract::This study presents the characteristics of 20 children (17 female) with NIDDM who required oral hypoglycemic agent (OHA) therapy. A family history of NIDDM was present in 55%. None had islet cell antibodies (ICA) or glutamic acid decarboxylase (GAD) antibodies. Tolbutamide was the drug of choice; glibenclamide was int...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289803700209
更新日期:1998-02-01 00:00:00
abstract::This study aims to explore the changes in endothelin-1 (ET-1), plasma neuropeptide Y, and calcitonin gene-related peptide (CGRP) in child patients before and after operation. A total of 80 child patients with congenital heart disease (CHD) complicated with pulmonary hypertension (PH) were enrolled and divided into con...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820948261
更新日期:2021-01-01 00:00:00
abstract::Pediatric obesity, which has reached epidemic proportions in the United States in the past 10 years, translates directly into rising rates of adult obesity. This study assessed the impact of a school, family, community, and industry-based primary intervention project on the rates of overweight and obesity in a rural c...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922807299315
更新日期:2007-09-01 00:00:00
abstract::The authors describe 4 first rib fractures in 3 infants, highlighting the difficulty in detecting first rib fractures on skeletal survey. All 4 fractures were the result of physical abuse. A literature search does not find a case of first rib fracture in a healthy infant that is not the result of child abuse. The diag...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922811430343
更新日期:2012-05-01 00:00:00
abstract::A considerable percentage of American children and adults fail to learn adequate literacy skills and read below a third grade level. Shared book reading is perhaps the single most important activity to prepare young children for success in reading. The primary objective of this manuscript was to critically review the ...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/0009922813507995
更新日期:2014-04-01 00:00:00
abstract::Little is known of the characteristics of children experiencing school dysfunction who are evaluated by multidisciplinary teams. The records of 87 children seen during a calendar year were reviewed and information was gathered regarding their age, sex, and referral source. In addition, the chief concerns of the child'...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288802700406
更新日期:1988-04-01 00:00:00
abstract::A 12-year-old girl presented with weakness, diplopia, and lethargy after a prodrome of gastroenteritis. Laboratory studies were compatible with a diagnosis of hemolytic uremic syndrome. She developed seizures that were controlled by diphenylhydantoin and valium. In spite of peritoneal dialysis and fresh frozen plasma ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288702601208
更新日期:1987-12-01 00:00:00
abstract::This study examines primary care provider (PCP) experiences with the initial parental disclosure of cystic fibrosis (CF) newborn screening (NBS) results in order to identify methods to improve parent-provider communication during the CF NBS process. PCPs of infants who received positive CF NBS results participated in ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922814545619
更新日期:2015-01-01 00:00:00
abstract::Paroxysmal supraventricular tachycardia is a common problem in infancy and childhood. Past treatment has included digitalis and nonselective beta blockers (propranolol). We describe a new mode of therapy with a cardioselective beta blocker (metoprolol) that may be of use in patients resistant to standard therapy. ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288302200714
更新日期:1983-07-01 00:00:00
abstract::An acutely ill 4-year-old girl with Rocky Mountain spotted fever (RMSF) was found to have a coagulation inhibitor. This child had no serious bleeding manifestations and minimal hemorrhagic skin manifestations despite severe RMSF, concurrent thrombocytopenia, as well as the coagulation inhibitor. Hemostatic abnormaliti...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288702600905
更新日期:1987-09-01 00:00:00
abstract::The purpose of the current study was to develop syndrome-specific standardized growth curves for growth hormone-treated Prader-Willi syndrome (PWS) individuals aged 0 to 18 years. Anthropometric growth-related measures were obtained on 171 subjects with PWS who were treated with growth hormone for at least 40% of thei...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815617973
更新日期:2016-09-01 00:00:00
abstract::The Vaccines for Children (VFC) program distributes one half of all vaccines administered to US children. Compared with commercial vaccine distribution, VFC distribution is more complex. This prospective observational study compares the delivery and administration of VFC versus non-VFC influenza vaccine in US pediatri...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922812470868
更新日期:2013-03-01 00:00:00