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Association of hyperglycemia on allograft function in the early period after renal transplantation.

Abstract：

:Hyperglycemia is common following renal transplantation. This study was conducted to evaluate the relationship of perioperative serum glucose levels and acute rejection in 100 nondiabetic patients who underwent renal transplantation. Blood glucose was measured immediately following surgery and every 6 hours during the first 48 hours posttransplant as well as for 1 month to evaluate occurrence of acute rejection episodes (ARE). The rate of ARE was 33%. The mean blood glucose level immediately after surgery in patients with versus without ARE was 249.67 +/- 61.78 and 184.82 +/- 73.35 mg/dL, respectively (P=.000). There was no significant correlation between ARE and donor or recipient age or sex, delayed graft function, type of donor, or treatment. This study suggested a correlation between immediate blood glucose and ARE. In this regard, blood glucose monitoring and control during operation and immediate postoperatively may reduce the acute rejection rate.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Ganji MR,Charkhchian M,Hakemi M,Nederi GH,Solymanian T,Saddadi F,Amini M,Najafi I

doi

10.1016/j.transproceed.2007.03.030

subject

Has Abstract

pub_date

2007-05-01 00:00:00

pages

852-4

issue

4

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(07)00364-8

journal_volume

39

pub_type

杂志文章

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