Antibodies to Epstein-Barr virus in nasopharyngeal carcinoma, tonsillar carcinoma and control groups.

Abstract:

:In the sera of 17 patients with nasopharyngeal carcinoma (NPC) and of 19 patients with tonsillar carcinoma (TC) the titres of IgA, IgG and IgM antibodies to EBV VCA (viral capsid antigen) and of IgG antibodies to EBV EA (early antigen) were determined by the indirect immunofluorescence (IF) method. Significant difference was observed in the frequency of IgA antibodies to EBV VCA and IgG antibodies to EBV EA between NPC patients and controls. There was also a significant difference between the frequency of IgM antibody to EBV VCA and EBV EA antibody titres in TC patients and controls. The geometric mean titre (GMT) of IgG antibodies to EBV VCA was significantly higher in the NPC and TC patients as compared to controls.

journal_name

Acta Virol

journal_title

Acta virologica

authors

Oberender H,Nowak R,Donner A,Kunkel M,Gärtner L,Scholtz HJ

subject

Has Abstract

pub_date

1983-05-01 00:00:00

pages

277-81

issue

3

eissn

0001-723X

issn

1336-2305

journal_volume

27

pub_type

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