Diurnal variation of urinary MHPG in unipolar and bipolar depressives.

Abstract:

:In eight bipolar depressives, 11 unipolar depressives, and 15 healthy controls urinary excretion of MHPG was measured at 3-h intervals over one 24-h period. Bipolars excreted smaller amounts of MHPG than unipolars and controls, especially at night. MHPG excretion was significantly dependent on time of day in the control group only. In the patients maximum excretion showed a tendency to occur earlier in the day than in controls. Minima were unaffected. There were indications that tricyclic antidepressants advance MHPG phases.

journal_name

Acta Psychiatr Scand

authors

Giedke H,Gaertner HJ,Mahal A

doi

10.1111/j.1600-0447.1982.tb00932.x

subject

Has Abstract

pub_date

1982-09-01 00:00:00

pages

243-53

issue

3

eissn

0001-690X

issn

1600-0447

journal_volume

66

pub_type

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