Abstract:
BACKGROUND:Atypical depression may show lowered rather than raised short-term cortisol levels. Atypical major depressive episodes (A-MDE) may also be more closely linked to environmental factors and show overlap with somatic symptom disorders. Hair specimens allow measuring long-term cortisol levels. METHODS:Twenty-seven A-MDE and 44 NA-MDE patients and 40 matched controls were tested. Measures of hair cortisol concentration [HCC] covering the previous 3 months and short-term cortisol parameters (six saliva specimens to assess the cortisol awakening response [CAR] and total daily cortisol output calculated as the area under the curve [AUCg]) were taken alongside measures of environmental factors and clinical variables. RESULTS:There were no differences in HCC between the three groups (P = 0.8), and no difference in the CAR (P = 0.95). However, A-MDE showed lowered short-term cortisol output (AUCg) compared to controls (P = 0.04). A-MDE patients also reported a higher number of daily hassles, and higher levels of fatigue and impaired concentration than NA-MDE. CONCLUSIONS:Normal long-term (HCC) and reduced short-term (AUCg) cortisol levels in A-MDE could suggest a disrupted long-term cortisol rhythm, perhaps affected by environmental factors or by certain symptoms, such as mid-nocturnal insomnia. However, other underlying explanations for these findings should also be investigated in the future.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Herane-Vives A,de Angel V,Papadopoulos A,Wise T,Chua KC,Strawbridge R,Castillo D,Arnone D,Young AH,Cleare AJdoi
10.1111/acps.12852subject
Has Abstractpub_date
2018-03-01 00:00:00pages
216-230issue
3eissn
0001-690Xissn
1600-0447journal_volume
137pub_type
杂志文章,多中心研究abstract::This investigation studied by direct interviews in a randomly selected sample of 58 Swedish unbroken families, factors of importance for the father's experience of his preschool child. The father's experience of his child was shown to correlate with the child's experience of him. Fathers experiencing their child in a ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1980.tb00563.x
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVE:Selective outcome reporting poses serious implications on our evidence base for best practice. The extent to which selective outcome reporting and trial registration occurs in the wider psychotherapy literature needs to be investigated. METHOD:Randomized controlled psychotherapy trials published between 2010...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/acps.12647
更新日期:2017-01-01 00:00:00
abstract::An increased death rate has been found in patients treated in hospital for neurosis but the reasons for this are not known. A case note study is described in which 37 patients who were treated in hospital for neurosis and subsequently died are compared with a cross-matched sample of treated neurotics who were alive at...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1979.tb06970.x
更新日期:1979-03-01 00:00:00
abstract::The clinical effect of cis(Z)-clopenthixol has been compared with that of clopenthixol, which is a mixture of the pharmacologically active cis(Z)-isomer and the inactive trans(E)-isomer. In the 2-month double-blind trial were included 57 psychotic patients, mainly schizophrenics. Ratings evaluating severity of illness...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0447.1978.tb03570.x
更新日期:1978-11-01 00:00:00
abstract:OBJECTIVE:The paper provides the first syllabus on the prevalence of mental disorders in old-age focusing on surveys conducted in the 15 countries, which comprised the 'old' European Union. METHOD:A systematic search of the literature published from 1990 onwards was conducted. RESULTS:Mental disorders in old-age are ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.2005.00632.x
更新日期:2006-05-01 00:00:00
abstract::Patients receiving lithium who had noticed changes in hair texture since starting that drug, described variously as hair losing its curl or wave, have a greater lithium concentration in hair than patients on lithium with no such complaints. ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb02626.x
更新日期:1985-10-01 00:00:00
abstract::The differentiating power of two individually related measures of outcome, target complaints and psychiatrists' evaluation of individually defined treatment objectives, were studied in two models of treatment planning, one with and one without active patient participation. Target complaints were measured at admission,...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb02789.x
更新日期:1987-03-01 00:00:00
abstract::Five different strategies were used to detect cases in which depressed behaviour occurred in both spouses within the same time period (simultaneous depression). Among 7068 references on depression in the literature, only one referred to a case of simultaneous depression. Of 8008 registered individuals hospitalized in ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1990.tb05482.x
更新日期:1990-05-01 00:00:00
abstract:OBJECTIVE:To give an update on epidemiological findings on sex differences in the prevalence of unipolar depression and putative risk factors. MATERIAL AND METHODS:Systematic review of the literature. RESULTS:Recent epidemiological research yields additional evidence for a female preponderance in unipolar depression,...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1034/j.1600-0447.2003.00204.x
更新日期:2003-09-01 00:00:00
abstract::Twenty patients with delirium tremens and related states were investigated from the time of admission until the acute state was over. Using strict diagnostic criteria the material was divided into two groups according to the severity of the clinical condition; nine patients had fully developed delirium tremens (grade ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1979.tb00550.x
更新日期:1979-11-01 00:00:00
abstract::Little attention has been payed to the classification of psychotic symptoms in dementia sufferers. This article compares the etiology of delusions, visual hallucinations and delusional misidentification and examines the value of factors generated from principal components analysis as a possible classificatory system i...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1995.tb09544.x
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to relate measures of psychoanalytically derived personality traits to descriptive diagnosis and psychopathology in severe mental disorders. METHOD:Sixty-one consecutive first-episode patients with schizophrenia, bipolar disorder and severe major depression were interviewed. Persona...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2003.00289.x
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:The role of baseline severity as effect modifier in various psychiatric disorders is a topic of controversy and of clinical import. This study aims to examine whether baseline severity modifies the efficacy of various antidepressants for major depression through individual participant data (IPD) meta-analysis...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,meta分析
doi:10.1111/acps.12886
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:To identify psychopathological predictors for suicide in a population of major depressed Diagnostic Statistical Manual-III (DSM-III) in-patients. METHOD:A total of 210 previous participants in multicentre antidepressant drug trials, carried out in a randomized double-blind design, were followed prospectively...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-06-01 00:00:00
abstract::In recent discussions on euthanasia the question about mercy killing without consent of mentally ill persons has turned up, particularly in cases of hopeless suffering among senile or chronically insane patients. Possible analogies to the actions under the German Nazi-regimen and relations to the concept of Social Dar...
journal_title:Acta psychiatrica Scandinavica
pub_type: 历史文章,杂志文章
doi:10.1111/j.1600-0447.1982.tb00832.x
更新日期:1982-02-01 00:00:00
abstract:OBJECTIVE:To develop a short, 5-item measure of the core symptoms of depression based on the 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16 ) and to evaluate psychometric properties of this new measure (Very Quick Inventory of Depressive Symptomatology - Self-Report: VQIDS-SR5 ). METHOD:...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12720
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To study the outcome of a sequential treatment protocol in elderly, severely depressed in-patients. METHOD:All 81 patients from a 12-week double-blind randomized controlled trial (RCT) comparing venlafaxine with nortriptyline were asked to participate in a 3 year follow-up study. Thirty-two patients who did ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0447.2008.01295.x
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to further evaluate the oestrogen hypothesis of schizophrenia, which postulates low oestradiol levels to be a risk factor for these disorders. A possible influence of neuroleptic-induced hyperprolactinaemia was to be addressed. METHOD:Sex hormones were measured and cycle phase asses...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1046/j.1600-0447.2003.00251.x
更新日期:2004-04-01 00:00:00
abstract::For patients dependent on benzodiazepines alone, or in combination with alcohol and/or other legal and illegal drugs, observed mortality rates were compared with the average population, and, in cases of isolated benzodiazepine dependence, also with a control group of non-dependent patients chosen to match each depende...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb02693.x
更新日期:1986-03-01 00:00:00
abstract:OBJECTIVE:Although previous studies have revealed an association between androgens and aggression, there is a lack of knowledge of this issue in different mental disorders. METHOD:The associations between serum testosterone levels and criminal behaviour in different mental disorders were examined using data collected ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb07240.x
更新日期:1999-05-01 00:00:00
abstract::Resting and pre-infusion heart rates recorded in 66 panic disorder patients revealed no significant differences between panickers and nonpanickers. There was also no significant difference in pre-fusion heart rates between either lactate or isoproterenol panickers and placebo nonpanickers. There was neither a sensitiz...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0447.1987.tb02750.x
更新日期:1987-01-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1993.tb03344.x
更新日期:1993-02-01 00:00:00
abstract::The purpose of this study was to test the transferability of the Marke-Nymann Temperament Scale (MNTS) using the Rasch item analysis. The results showed that the three Sjöbring personality dimensions Validity, Stability, and Solidity measured by the MNTS were without transferability. However, the item analysis demonst...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1978.tb06873.x
更新日期:1978-01-01 00:00:00
abstract::Thirty-seven patients with the diagnosis of senile dementia and 70 children aged 6 months to 4 years were observed in three tasks that stimulated exploratory behavior. The subjects were rated according to the frequencies of certain forms of behavior in 52 variables. It was assumed that certain behavior would be more f...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1976-04-01 00:00:00
abstract:OBJECTIVE:To assess the methodological value of studies that signaled one or more selective serotonin reuptake inhibitors (SSRIs) as teratogenic agents. METHOD:Medical literature, published in English (1980-November 2010), was searched using MEDLINE/PubMed, TOXNET, EMBASE, and The Cochrane Library to identify all arti...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.2011.01673.x
更新日期:2011-04-01 00:00:00
abstract::An ethological method was employed to validate the DSM-III subtyping of unipolar, nondelusional depression. The nonverbal behavior of 44 depressed outpatients was video-recorded during psychiatric interview. The DSM-III subtyping was not significantly associated with sex or level of education. Patients with major depr...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1990.tb05499.x
更新日期:1990-06-01 00:00:00
abstract:OBJECTIVE:The idea of cortical surface anomalies in subjects with intellectual disability (mental retardation) and schizophrenia can be traced back to early 20th century qualitative observations. Since it is unknown whether modern quantitative measures of cortical complexity and folding would retrieve those early empir...
journal_title:Acta psychiatrica Scandinavica
pub_type: 历史文章,杂志文章
doi:10.1111/acps.12243
更新日期:2014-09-01 00:00:00
abstract::Parental bonding patterns were studied in 52 female Japanese eating disorder outpatients with and without histories of sexual or physical abuse and with dissociation. Instruments included the Parental Bonding Instrument (PBI), the Dissociative Experiences Scale (DES) and the Dissociative Disorders Interview Schedule (...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1995.tb09782.x
更新日期:1995-04-01 00:00:00
abstract::A study of suicide among the nonnomadic Gypsies in three counties in Hungary revealed that they had a lower completed suicide rate but a higher attempted suicide rate than ethnic Hungarians. The rate of attempted suicide appeared to be higher in the younger, partially assimilated Gypsies as a result of the conflict be...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1990.tb01405.x
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:There is ongoing concern about the possible negative impact of ECT on neurocognitive functioning in older patients. In this study, we aimed to characterize the long-term cognitive effects of ECT in patients with late-life depression, using an extensive neuropsychological battery. METHODS:A total of 110 patie...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12942
更新日期:2018-09-01 00:00:00