Stimulus-secretion coupling in pancreatic acinar cells.

abstract：BACKGROUND:The prevalence of primary sclerosing cholangitis, a rare progressive liver disorder, is increasing with the advent of endoscopic retrograde cholangiography in the investigation of children with obscure liver disease. The etiology of primary sclerosing cholangitis is not known, clinical presentation is variab...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kagalwalla AF,Altraif I,Shamsan L,Omojola M,Khan H,Kagalwalla YA

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to use linear programming (LP) analyses to adapt New Complementary Feeding Guidelines (NCFg) designed for infants aged 6 to 12 months living in poor socioeconomic circumstances in Bogota to ensure dietary adequacy for young children aged 12 to 23 months. DESIGN:A secondary data analy...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tharrey M,Olaya GA,Fewtrell M,Ferguson E

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Little is known about the enteric protein loss in patients after a modified Fontan operation before the appearance of overt symptoms or signs of protein-losing enteropathy (PLE). The authors examined the possibility of using fecal alpha1-antitrypsin concentration measurements for the early detection of posto...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fujii T,Shimizu T,Takahashi K,Kishiro M,Ohkubo M,Akimoto K,Yamashiro Y

更新日期：2003-11-01 00:00:00

abstract：:Yogurt has been shown to inhibit, by various mechanisms, pathogenic bacterial growth in vitro, including that of the rabbit Escherichia coli strain RDEC-1. To determine whether this in vitro inhibition by yogurt has an in vivo counterpart, 60 newly weaned New Zealand rabbits were randomly assigned to receive a diet su...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Gotteland M,Pochart P,Dabbech M,Bisetti N,Desjeux JF

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVES:Glucagon-like peptide 2 (GLP-2) is a 33 amino acid peptide hormone released from enteroendocrine L-cells following nutrient ingestion. It has been shown to exert trophic effects on the gut. We set out to measure GLP-2 concentrations in blood in children with diarrhoea and malnutrition. METHODS:GLP-2 levels ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Besa EC,Chandwe K,Banda R,Munalula L,Kalomo L,Amadi B,Kelly P

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:Adult-based guidelines support the use of the pull (extraction) endoscopic technique in managing esophageal food bolus impactions (FBIs) but allow the consideration of the push (advancement) technique with caution based on available published literature. The North American Society for Pediatric Gastroenterol...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kriem J,Rahhal R

更新日期：2018-01-01 00:00:00

abstract：:The provision of optimal nutritional care is based on accurate estimations of patients' resting energy expenditure. The latter can be calculated with the use of predictive equations or measured with indirect calorimetry (IC). Owing to their ease of use, mathematical equations have largely replaced IC in clinical pract...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Carpenter A,Pencharz P,Mouzaki M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Many patients with chronic hepatitis C do not respond to antiviral treatment. In adult patients the re-treatment of these patients has been extensively investigated. Because the response to re-treatment in children is not well defined we evaluated the efficacy and safety of interferon (IFN)-alpha plus ribavi...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Gerner P,Hilbich J,Wenzl TG,Behrens R,Walther F,Kliemann G,Enninger A,Wirth S

更新日期：2010-08-01 00:00:00

abstract：:Ingestion of hyperosmolal formula (HOF) by neonatal piglets has been shown to cause significant time-dependent reduction in phase 3 myoelectric activity, which persists in the terminal ileum. To determine whether a single hyperosmolal meal leads to elevated concentrations of gastrointestinal (GI) hormones that inhibit...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Szabo JS,Rayford PL,Uthman E,Lobe TE

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVES:Celiac disease (CD) represents a spectrum, which includes cases with minor histological abnormalities (potential CD). The aim of this work is to evaluate the contribution of immunohistochemical analysis of duodenal biopsies to the diagnosis of gluten-related minor enteropathy. METHODS:Duodenal biopsies from...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tosco A,Maglio M,Paparo F,Greco L,Troncone R,Auricchio R

更新日期：2015-05-01 00:00:00

abstract：:Long-term follow-up of randomised trials and observational studies provide the best evidence presently available to assess long-term effects of nutrition, and such studies are an important component in determining optimal infant feeding practices. Attrition is, however, an almost inevitable occurrence with increasing ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fewtrell MS,Domellöf M,Hojsak I,Hulst JM,Kennedy K,Koletzko B,Mihatsh W,Stijnen T

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:Midgut volvulus with malrotation is typical in newborns. We present our experience to emphasize the importance of suspecting midgut volvulus as a cause of abdominal pain also beyond infancy, particularly in relation to malrotation, and the relevance of ultrasonographic (US) signs in its diagnosis. METHODS:A...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Esposito F,Vitale V,Noviello D,Di Serafino M,Vallone G,Salvatore M,Oresta P

更新日期：2014-12-01 00:00:00

abstract：:In a 10-week randomised cross-sectional study we used an 88-item questionnaire to assess the quality of life in 16 children (ages 8-17 years) with Crohn's disease and their families. The questionnaire covered six domains of health-related quality of life, including disease and its treatment, social, emotional, family,...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Rabbett H,Elbadri A,Thwaites R,Northover H,Dady I,Firth D,Hillier VF,Miller V,Thomas AG

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVES:Intestinal epithelial restitution is the first part in the process of mucosal repair after injury in the intestine. Integrity of the intestinal mucosal barrier is important as a first line of defense against bacteria and endotoxin. Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Richter JM,Schanbacher BL,Huang H,Xue J,Bauer JA,Giannone PJ

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:The coexistence of celiac disease (CeD) and eosinophilic esophagitis (EoE) in pediatric patients has been increasingly recognized. In the current study, we have aimed to assess the outcomes of therapeutic dietary interventions in a cohort of pediatric patients with CeD and EoE. METHODS:Pediatric patient reco...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Patton T,Chugh A,Padhye L,DeGeeter C,Guandalini S

更新日期：2019-08-01 00:00:00

abstract：:This clinical report aims to review key self-management and adherence issues in pediatric inflammatory bowel disease (IBD) and to provide recommendations for health care providers regarding evidence-based assessment and treatment approaches to promote optimal self-management. Self-management difficulties in the form o...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hommel KA,Greenley RN,Maddux MH,Gray WN,Mackner LM

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:The present understanding of inflammatory bowel disease pathogenesis mainly relies on studies of adult patients. Therefore, we studied the balance between T-effector and regulatory cells in pediatric inflammatory bowel disease. METHODS:Quantitative polymerase chain reaction and immunohistochemistry served to...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hölttä V,Klemetti P,Salo HM,Koivusalo A,Pakarinen M,Westerholm-Ormio M,Kolho KL,Vaarala O

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVES:The present study aims to identify the genotype-phenotype correlation in children with Peutz-Jeghers Syndrome (PJS) through the analysis of STK11 gene mutations in the context of clinical and pathological characteristics. METHOD:In this observational cohort study, the clinical characteristics of 18 families...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Zhao HM,Yang YJ,Duan JQ,Ouyang HJ,Liu L,Yi LC,Xiao ZH,Zheng Y,Peng L,Attard TM,Li DY,You JY

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Gastric lipase has an important compensatory function in neonatal fat digestion. The activity level of pepsin and its role in protein digestion is less well understood. We have, therefore, studied the ontogeny of lipase and pepsin in the ferret, a species with a neonatal fat digestion pattern similar to that...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hamosh M,Henderson TR,Hamosh P

更新日期：1998-02-01 00:00:00

abstract：:Thin frozen sections of 11 jejunal biopsies from 10 children at different stages of coeliac disease were stained by immunofluorescence technique using a panel of anti-HLA class I (A, B, C) and anti-HLA class II (DR and DQ) monoclonal antibodies. On the epithelium of flattened mucosa, in contrast with control sections,...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sarles J,Gorvel JP,Olive D,Maroux S,Mawas C,Giraud F

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVES:Liver nodularity occurs across the spectrum of cystic fibrosis liver disease (CFLD), from regenerative nodules to cirrhosis, and can occur without liver enzyme abnormalities. Our aims were to determine if incorporating abdominal ultrasound (US) with annual laboratory testing improves the detection of CFLD an...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sellers ZM,Lee LW,Barth RA,Milla C

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Gliadin proteins play a key role in the pathogenesis of celiac disease; however, as a screen for celiac disease, anti-gliadin antibody testing has been replaced by the more sensitive and specific serological assays for transglutaminase autoantibodies (TGAA). A new generation of anti-gliadin antibody assays...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Liu E,Li M,Emery L,Taki I,Barriga K,Tiberti C,Eisenbarth GS,Rewers MJ,Hoffenberg EJ

更新日期：2007-09-01 00:00:00

abstract：:The purpose of this retrospective review of the charts of 6 children who underwent surgical treatment of chylous ascites refractory to conservative measures between 1993 and 2006 was to evaluate the efficiency of fibrin glue application for control of lymph leakage. Five children had postoperative chylous ascites (neu...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Zeidan S,Delarue A,Rome A,Roquelaure B

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:Tissue transglutaminase (tTG) autoantibodies are serologic markers for celiac disease (CD). The aim was to determine the diagnostic sensitivity and specificity of different immunoglobulin isotypes against tTG. METHODS:Immunoglobulin A (IgA)-tTG, IgG-tTG, and IgG1-tTG were measured in radioligand binding ass...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Agardh D,Borulf S,Lernmark A,Ivarsson SA

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:In developed countries, small bowel histology in coeliac disease is a spectrum, ranging from normal with increased intraepithelial lymphocytes to the classic flat mucosa. In developing countries, mild to moderate enteropathies in children with chronic diarrhea and growth failure are assumed to be caused by t...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bhatnagar S,Gupta SD,Mathur M,Phillips AD,Kumar R,Knutton S,Unsworth DJ,Lock RJ,Natchu UC,Mukhopadhyaya S,Saini S,Bhan MK

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to describe the clinical experience with the anti-tumor necrosis factor chimeric monoclonal antibody, infliximab, in pediatric patients with Crohn disease in The Netherlands. DESIGN:Descriptive. METHODS:Clinical response and adverse effects of infliximab were recorded for pedia...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： de Ridder L,Escher JC,Bouquet J,Schweizer JJ,Rings EH,Tolboom JJ,Houwen RH,Norbruis OF,Derkx BH,Taminiau JA

更新日期：2004-07-01 00:00:00

abstract：:In this prospective study, neonates with clinical congenital syphilis were investigated to determine if penicillin therapy caused a deterioration in liver function. The relationship between circulating immune complexes and liver involvement was monitored, and the efficacy of steroid therapy as an adjunct in the treatm...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Venter A,Pettifor JM,Duursma J,Pudifin DJ,Smyth A,Becker PJ

更新日期：1991-04-01 00:00:00

abstract：OBJECTIVES:Because of a variable clinical picture, most children with celiac disease remain unrecognized without active serologic screening. Because, however, many patients are asymptomatic, the justification for screening remains unclear. We assessed health and well-being and the effect of a 1-year gluten-free diet in...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kinos S,Kurppa K,Ukkola A,Collin P,Lähdeaho ML,Huhtala H,Kekkonen L,Mäki M,Kaukinen K

更新日期：2012-10-01 00:00:00

abstract：:The objective of this study was to evaluate the accuracy of an indirect immunofluorescence (IIF) test for serodiagnosis of Helicobacter pylori infection in children and to determine how the test is affected by the presence of antibodies against Campylobacter jejuni. We studied 65 consecutive children (two with endosco...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Rocha GA,Queiroz DM,Mendes EN,de Carvalho AS,de Oliveira AM,de Moura SB

更新日期：1993-04-01 00:00:00

abstract：:Few advances would contribute more to the growth and well-being of infants and children in the developing world than the making available of acceptable staple foods that are easy to grow and process, nutritionally complete enough to serve as the major weaning food, and safe without refrigeration. High-fat quality-prot...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Graham GG

更新日期：1993-08-01 00:00:00