Preparation and storage of "leukocyte-depleted single donor" platelet concentrate: a step forward in effective haemotherapy.

Abstract:

:"Leukocyte-depleted" platelet concentrates (LD-SDPC) were prepared by cotton-wool and by polyester filtration of "leukocyte-poor" PC collected by the elutriation technique. The storage characteristics of LD-SDPC were comparable to those of the filtered pools of multiple donor platelet concentrates (LD-MDPC). However, LD-SDPC were less activated and less damaged than LD-MDPC over a 7-day storage period, as evidenced by beta-thromboglobin percent release and lactic dehydrogenase percent leakage in both products. LD-SDPC were prophylactically transfused to 12 thrombocytopenic patients; the mean bleeding time was shortened from 12 min 20 sec to 4 min 39 sec. Corrected count increment (CCI) was 22.8 at 1 hr and 14.1 at 24 hr compared to 15.5 and 10.0, respectively, with standard PCs.

journal_name

J Clin Apher

authors

Elias MK,de Wolf JT,Blom N,Rijskamp L,Halie RM,Smit Sibinga CT

doi

10.1002/jca.2920060304

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

143-9

issue

3

eissn

0733-2459

issn

1098-1101

journal_volume

6

pub_type

杂志文章
  • The use of fluid boluses to safely perform extracorporeal photopheresis (ECP) in low-weight children: a novel procedure.

    abstract::Apheresis procedures in small children are technically challenging and require special planning with attention to extracorporeal volume. Discontinuous procedures such as extracorporeal photopheresis (ECP) require additional consideration. Alternative methods to perform ECP have been utilized in small children that req...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.20231

    authors: Schneiderman J,Jacobsohn DA,Collins J,Thormann K,Kletzel M

    更新日期:2010-01-01 00:00:00

  • Advanced lytic lesion is a poor mobilization factor in peripheral blood stem cell collection in patients with multiple myeloma.

    abstract::This study examined the incidence and predictors of peripheral blood stem cell (PBSC) mobilization failure in patients with multiple myeloma (MM). Retrospective data for 104 patients who received granulocyte colony-stimulating factor (G-CSF) alone or with cyclophosphamide as mobilization regimens were analyzed. The ra...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21326

    authors: Jung SH,Yang DH,Ahn JS,Kim YK,Kim HJ,Lee JJ

    更新日期:2014-12-01 00:00:00

  • Modification of the leukapheresis procedure for use in rhesus monkeys (Macaca mulata).

    abstract::One of the most serious problems in applying leukapheresis to human infants is the large extracorporeal blood volume (ECV), resulting in substantial loss of platelets and red blood cells (RBCs). In this study, we developed a safe and effective modified procedure to collect peripheral blood stem cells (PBSCs) from rhes...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.10043

    authors: Ageyama N,Kimikawa M,Eguchi K,Ono F,Shibata H,Yoshikawa Y,Terao K

    更新日期:2003-01-01 00:00:00

  • Comparison of platelet loss during leukocyte reduction at 4, 24, and 48 hours postcollection using a Closed System Apheresis Kit with Integral filter.

    abstract::Prestorage leukocyte reduction of platelet concentrates may reduce adverse effects of transfusion while affording better quality control. Platelets and leukocytes may undergo activation during storage, which could affect the performance of leukocyte reduction filters. The purpose of this study was to evaluate the effi...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/(sici)1098-1101(1997)12:1<14::aid-jca4>3.0

    authors: Jin YS,Mintz PD

    更新日期:1997-01-01 00:00:00

  • Acute thrombotic thrombocytopenic purpura following abdominal surgeries: a report of three cases.

    abstract::Acute thrombotic thrombocytopenic purpura (TTP) occurred in three patients following abdominal surgeries. One patient underwent extensive lysis for intestinal adhesions with bowel resection, another cholecystectomy for acute cholecystitis, and the third right colectomy and partial intestinal resection for colon cancer...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/1098-1101(2000)15:3<176::aid-jca4>3.0.co;2

    authors: Chang JC,El-Tarabily M,Gupta S

    更新日期:2000-01-01 00:00:00

  • Comparison of COBE Spectra software version 4.7 PBSC and version 6.0 auto PBSC program.

    abstract::Until recently, the collection of peripheral blood progenitor cells (PBPC) has been semi-automated by using the COBE Spectra, with the operator manually maintaining the position of the white cells being collected. The COBE Spectra Version 6.0 apheresis device offers the user an automated program for the collection of ...

    journal_title:Journal of clinical apheresis

    pub_type: 临床试验,杂志文章

    doi:10.1002/(sici)1098-1101(1999)14:1<26::aid-jca5>3.0

    authors: Wilke R,Brettell M,Prince HM,Wolf M,McKenna R,Serpell E,Molloy M,Stevens H,Quinn M,Gates P,Chapple P

    更新日期:1999-01-01 00:00:00

  • Efficacy and safety of adsorptive granulomonocytapheresis in Chinese patients with ulcerative colitis: A retrospective analysis of 50 cases with focus on factors impacting clinical efficacy.

    abstract:BACKGROUND:Myeloid-derived leucocytes, a major source of inflammatory cytokines, play an important role in the exacerbation of ulcerative colitis (UC). Selective depletion of myeloid leucocytes by adsorptive granulomonocytapheresis (GMA) with an Adacolumn should alleviate inflammation and promote remission. However, th...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21787

    authors: Li N,Mao J,Tang H,Zhu L,Tan X,Bi J,Wu H,Chen X,Wang Y

    更新日期:2020-08-01 00:00:00

  • The impact of motivational interviewing on self-perceived burden in patients receiving therapeutic plasma exchange.

    abstract:BACKGROUND:Autoimmune disorders and neurodegenerative disorders take a physical and emotional toll on patients that undergo therapeutic plasma exchange (TPE) treatments. Previous literature has shown that these patients may feel a greater sense of self-burden. Motivational Interviewing (MI) is a technique used in vario...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21645

    authors: Dill R,Olson DM,Session-Augustine N,Mariani D,Stutzman SE

    更新日期:2018-10-01 00:00:00

  • Hematopoietic stem cell processing and cryopreservation.

    abstract::Either bone marrow or peripheral blood may be harvested to provide hematopoietic stem cells (HSC) for autologous transplantation. Both, however, comprise heterogeneous cell populations. The HSC necessary for successful engraftment constitute a very small fraction of the cells harvested. After collection, the harvested...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,评审

    doi:10.1002/jca.2920070307

    authors: Rowley SD

    更新日期:1992-01-01 00:00:00

  • Factors affecting platelet yield and their impact on the platelet increment of patients receiving single donor PLT transfusion.

    abstract::The aim of this study was to analyze the impact of various donor and machine parameters on PLT yield in 127 PLT apheresis procedures, to optimize PLT yield achieving clinical and economic advantages. One hundred and twenty-seven apheresis procedures were analyzed. Age, gender, volume processed, Hb, and PLT precounts w...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.20116

    authors: Enein AA,Hussein EA,El Shafie S,Hallouda M

    更新日期:2007-02-01 00:00:00

  • Plasma exchange conditioning for ABO-incompatible renal transplantation.

    abstract::The supply of deceased donor kidneys is inadequate to meet demand. To expand the pool of potential donors, ABO-incompatible transplants from living donors have been performed. We present the Mayo Clinic experience with such transplants. Enrollment was open to patients when the only available potential living kidney do...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.20002

    authors: Winters JL,Gloor JM,Pineda AA,Stegall MD,Moore SB

    更新日期:2004-01-01 00:00:00

  • Adsorption of anaphylatoxins from the plasma of systemic lupus erythematosus patients using dextran sulfate cellulose columns.

    abstract::Complement-derived anaphylatoxin may be one of the causes of vascular injury and an indicator of activity in systemic lupus erythematosus (SLE). The present study examines the effectiveness of dextran sulfate (DS) column immunoadsorption treatment to remove anaphylatoxins (C3a, C4a, and C5a) from the blood of patients...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/(sici)1098-1101(1998)13:3<108::aid-jca3>3.

    authors: Matsuki Y,Suzuki K,Kawakami M,Ishizuka T,Hidaka T,Nakamura H

    更新日期:1998-01-01 00:00:00

  • Physician coverage of therapeutic apheresis.

    abstract::A "snapshot" survey of physician coverage for evaluation and supervision of therapeutic apheresis procedures shows significant variation in current clinical practice between 39 blood center-and 41 non-blood center-based programs. Whereas 56% of blood center-based programs usually require physician's "in person" evalua...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.2920100405

    authors: Woll JE

    更新日期:1995-01-01 00:00:00

  • First successful use of leukocyte apheresis as maintenance therapy for Crohn's disease in the United Kingdom.

    abstract::We describe the case of a 24 year old male with severe fistulating Crohn's disease who failed mutliple modalities of medical and surgical therapy. We present objective and subjective evidence of disease remission after induction and maintenance treatment with leukocyte apheresis. This is the first described case of su...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21308

    authors: Tate D,Cairnes V,Valori R,Makins R

    更新日期:2014-06-01 00:00:00

  • The sex parameter in estimation of total blood volume for pediatric erythrocytapheresis.

    abstract:BACKGROUND AND OBJECTIVES:Estimation of the total blood volume (TBV) is fundamental to the control of automated red cell exchange (RCE). Error in the TBV estimate can produce outcomes that deviate from the prescribed targets, and may endanger the patient. Both the Spectra Optia and the COBE Spectra use the Nadler formu...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21748

    authors: Colavita D,Kim HC,Friedman DF

    更新日期:2019-12-01 00:00:00

  • Therapeutic plasma exchange may adjust IL-6 and TGF-β signals in relapsed MS patients peripheral blood.

    abstract:OBJECTIVE:Effects of therapeutic plasma exchange (TPE) on immune cells and their cytokine production in MS, are unknown. Since interleukine-6 and tumor growth factor-β have critical roles in MS immunopathogenesis, the impacts of TPE on the expression of these cytokines and their receptors on the surface of CD4+ T lymph...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21755

    authors: Jamshidian A,Abd-Nikfarjam B,Khademi Z,Shaygannejad V,Salehi M

    更新日期:2020-04-01 00:00:00

  • Therapeutic plasma exchange and renal related vasculitis: therapeutic apheresis academy 2010.

    abstract::Therapeutic plasma exchange (TPE), a form of extracorporeal therapy, has been used in the management of many systemic conditions some of which include the systemic vasculitides that affect the kidneys. The following is a mini review of what is known about renal related indications for TPE in such conditions and the ev...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,评审

    doi:10.1002/jca.20306

    authors: Balogun RA,Abdel-Rahman EM

    更新日期:2011-01-01 00:00:00

  • Protein A immunoadsorption treatment in hematology: an overview.

    abstract::Staphylococcal protein A efficiently binds immunoglobulins and circulating immune complexes (CIC) and provides an effective medium to remove immunoglobulins and CICs from plasma while sparing albumin and most coagulation proteins. Although it activates the complement system its clinical use abrogates the need for plas...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,评审

    doi:10.1002/jca.2920090109

    authors: Howe RB,Christie DJ

    更新日期:1994-01-01 00:00:00

  • Comparison of demographics and motivations of highly committed whole blood and platelet donors.

    abstract::To compare donor demographics and motivations for donation, we surveyed 159 consecutive whole blood donors (WD) and 146 consecutive plateletpheresis donors. All donors had donation experiences of at least 2 gallons (i.e., 16 previous donations). Evaluation of answers to fixed-response and open-ended questions revealed...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.2920080206

    authors: Julius CJ,Sytsma SR

    更新日期:1993-01-01 00:00:00

  • Apheresis red blood cells associated with repeated hemolysis during blood priming of the Cellex Photopheresis System.

    abstract::Extracorporeal photopheresis (ECP) in young pediatric patients has a risk for procedural hypotension and anemia due to extracorporeal fluid shifts. A standard mitigation policy in these patients is to prime the device with packed red blood cells (RBC) or whole blood. We now report multiple episodes of hemolysis while ...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21740

    authors: Cooling L,Thompson T,Downs T,Abusin G,Yanik G

    更新日期:2019-12-01 00:00:00

  • Report of the ASFA apheresis registry study on Wilson's disease.

    abstract:PURPOSE:Wilson's disease is a rare autosomal recessive genetic disorder that results in accumulation of copper in the liver, brain, cornea and kidney. Therapeutic plasma exchange (TPE) has been used to remove copper and provide a bridge to liver transplantation. We report here the collective experiences through the ASF...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jca.21396

    authors: Pham HP,Schwartz J,Cooling L,Hofmann JC,Kim HC,Morgan S,Pagano MB,Schneiderman J,Winters JL,Yamada C,Wong EC,Wu Y

    更新日期:2016-02-01 00:00:00

  • Improved red cell quality after erythroplasmapheresis with MCS-3P.

    abstract::The cell separator MCS-3P is an apheresis system offering the flexibility to collect standardized red blood cells, plasma, and/or platelets from one donor. Two different programs were used for the red cell apheresis--RBCP (collection of one unit of red cells and two units of plasma) and RBCPS (one unit of red cells an...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.2920090308

    authors: Matthes G,Tofote U,Krause KP,Pawlow I,Kucera W,Lerche D

    更新日期:1994-01-01 00:00:00

  • Ex vivo expansion of apheresis-derived peripheral blood hematopoietic progenitors.

    abstract::Because the administration of hematopoietic growth factors and the use of stem cell support often fails to alleviate the neutropenic phase induced by cytotoxic drugs, several investigators have attempted to expand ex vivo hematopoietic progenitors for clinical use. These attempts have clearly shown that the cultured c...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.10012

    authors: Estrov Z,Huh YO,Ginsberg CF,Harris D,Van Q,Mirza NQ,Talpaz M,Korbling M

    更新日期:2002-01-01 00:00:00

  • Management of systemic unfractionated heparin anticoagulation during therapeutic plasma exchange.

    abstract:BACKGROUND:Therapeutic plasma exchange (TPE) may remove medications from the patient's plasma. Data is limited on the effect of TPE on unfractionated heparin (UFH). STUDY DESIGN AND METHODS:A retrospective review was performed of patients receiving TPE and continuous IV infusion UFH from 1/1/2008 to 6/30/2010. TPE wit...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21441

    authors: Kaplan A,Raut P,Totoe G,Morgan S,Zantek ND

    更新日期:2016-12-01 00:00:00

  • Erythrocytapheresis is a valid and safe therapeutic option in dysmetabolic iron overload syndrome.

    abstract::Dysmetabolic iron overload syndrome is a rare event causing hepatic impairment with serious long-term side effects. Here, we describe a case of metabolic syndrome-related hepatic iron overload that showed a rapid, effective, and safe response to erythrocytapheresis. J. Clin. Apheresis 31:443-447, 2016. © 2015 Wiley Pe...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21434

    authors: Vetro C,Rosso R,Palmucci S,Russello M,Colletta G,Romeo MA,Ximenes B,Romano A,Palumbo GA,Di Raimondo F

    更新日期:2016-10-01 00:00:00

  • Extracorporeal circuit heparinization in selective low density lipoprotein apheresis: changes in patient hemostasis and low molecular weight heparin benefit.

    abstract::Treatment by low density lipoprotein (LDL) apheresis using dextran sulfate columns (DSC) leads to hemostasis alterations with prolonged activated partial thromboplastin time (APTT) of more than 120 seconds. In order to explain this hypocoagulability, we studied hemostasis parameters both in patients and in the extraco...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.2920080302

    authors: Lorenzini JL,Dutrillaux F,Mousson C,Lassale B,Maynadié M,Rifle G

    更新日期:1993-01-01 00:00:00

  • Acute hemolytic transfusion reaction in a pediatric patient following transfusion of apheresis platelets.

    abstract::The practice of transfusing ABO-incompatible platelets, driven primarily by concerns about inventory management, has been considered generally safe because the accompanying plasma is usually diluted in the recipient's total blood volume. However, if the platelet product contains a large volume of plasma or a high conc...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.20072

    authors: Sapatnekar S,Sharma G,Downes KA,Wiersma S,McGrath C,Yomtovían R

    更新日期:2005-12-01 00:00:00

  • Predictive factors for inadequate stem cell mobilization in Chinese patients with NHL and HL: 14-year experience of a single-center study.

    abstract:BACKGROUND:Factors affecting progenitor cell mobilization in patients with non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL) are incompletely understood. The aim of this retrospective study was to determine which factors are crucial for effective mobilization and collection of autologous peripheral blood stem ce...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21204

    authors: Han X,Ma L,Zhao L,He X,Liu P,Zhou S,Yang J,Qin Y,Yang S,Yao J,Shi Y

    更新日期:2012-01-01 00:00:00

  • Indications for and outcomes of therapeutic plasma exchange after cardiac transplantation: A single center retrospective study.

    abstract:INTRODUCTION:Limited data are available describing indications for and outcomes of therapeutic plasma exchange (TPE) in cardiac transplantation. METHODS:In a retrospective study of patients who underwent cardiac transplantation at Duke University Medical Center from 2010 to 2014, we reviewed 3 TPE treatment patterns: ...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21622

    authors: Onwuemene OA,Grambow SC,Patel CB,Mentz RJ,Milano CA,Rogers JG,Metjian AD,Arepally GM,Ortel TL

    更新日期:2018-08-01 00:00:00

  • Physiological measurements corroborate symptomatic improvement after therapeutic leukapheresis in a pregnant woman with chronic myelogenous leukemia.

    abstract::Therapeutic leukapheresis can control the white blood cell count (WBC) of pregnant women with chronic myelogenous leukemia (CML) who have hyperleukocytosis without leukostasis. The medical justification for this treatment has not been objectively documented. We report a 27-year-old woman, diagnosed with CML at 10-week...

    journal_title:Journal of clinical apheresis

    pub_type:

    doi:10.1002/jca.21410

    authors: Galera P,Haynes S,Sulmasy P,Bailey JA,Greene M,Vauthrin M,Brettler D,Liebmann J,Mark Madison J,Weinstein R

    更新日期:2016-08-01 00:00:00