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Plasma estrone, estradiol, estriol, progesterone, and 17-hydroxyprogesterone in human pregnancy. I. Normal pregnancy.

Abstract：

:To describe normal relationships between the various plasma unconjugated estrogens and progesterone during the second half of human pregnancy, the plasma concentrations of progesterone, 17-hydroxyprogesterone (17-OHP), and unconjugated estrone (E1), estradiol (E2), and estriol (E3) were measured in 126-310 normal women. Progesterone and unconjugated E1, E2, and E3 increased gradually throughout later pregnancy; 17-OHP increased only after the thirty-third week. At term the mean value of progesterone was 9 times higher than that 17-OHP. Throughout pregnancy the mean value of E2 was higher than that of E1 or E3. During the second half of pregnancy the ratios of progesterone to estradiol and estriol and of estradiol to estriol remained unchanged, indicating no preferential increase of plasma concentration of maternal or fetal hormones.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Tulchinsky D,Hobel CJ,Yeager E,Marshall JR

doi

10.1016/0002-9378(72)90185-8

subject

Has Abstract

pub_date

1972-04-15 00:00:00

pages

1095-100

issue

8

eissn

0002-9378

issn

1097-6868

pii

0002-9378(72)90185-8

journal_volume

112

pub_type

杂志文章

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