Differential symptom response to parenteral estrogen and/or androgen administration in the surgical menopause.

Abstract:

:The investigation of estrogen and/or androgen administration on physical and psychological symptoms in the surgical menopause was carried out in a prospective, double-blind, crossover design. When patients who received either a combined estrogen-androgen drug or androgen alone were compared with those who received estrogen alone or placebo, energy level, well-being, and appetite were increased (p less than 0.01). The androgen-containing preparations also induced lower somatic, psychological, and total scores on the menopausal index. Superior functioning in the androgen-treated groups occurred in association with higher plasma testosterone levels during the treatment phases (p less than 0.01). These data suggest that reduced levels of circulating testosterone subsequent to bilateral oophorectomy may play an important role in the development of physical and psychological symptoms that are frequent sequelae of this surgical procedure.

journal_name

Am J Obstet Gynecol

authors

Sherwin BB,Gelfand MM

doi

10.1016/0002-9378(85)90001-8

subject

Has Abstract

pub_date

1985-01-15 00:00:00

pages

153-60

issue

2

eissn

0002-9378

issn

1097-6868

pii

0002-9378(85)90001-8

journal_volume

151

pub_type

临床试验,杂志文章
  • Safety of metronidazole in pregnancy: a meta-analysis.

    abstract:OBJECTIVE:Our purpose was to determine from published experience in humans whether metronidazole exposure during the first trimester of pregnancy is associated with an increased teratogenic risk. STUDY DESIGN:All published articles reporting on metronidazole use during pregnancy were screened by two independent review...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,meta分析

    doi:10.1016/0002-9378(95)90567-7

    authors: Burtin P,Taddio A,Ariburnu O,Einarson TR,Koren G

    更新日期:1995-02-01 00:00:00

  • Maternal serum alpha-fetoprotein and dimeric inhibin A detect aneuploidies other than Down syndrome.

    abstract:OBJECTIVE:Our purpose was to determine whether the combination of maternal serum alpha-fetoprotein, free human chorionic gonadotropin-beta, dimeric inhibin A, and maternal age detects aneuploidies other than Down syndrome. STUDY DESIGN:We retrieved stored serum from pregnancies complicated by aneuploidies other than D...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(98)70198-x

    authors: Wenstrom KD,Chu DC,Owen J,Boots L

    更新日期:1998-10-01 00:00:00

  • The etiology of fetal acidosis as determined by umbilical cord acid-base studies.

    abstract:OBJECTIVE:Our purpose was to determine whether umbilical cord acid-base values might be used to differentiate abruptio placentae from cord prolapse. STUDY DESIGN:By use of a retrospective study design, umbilical cord blood acid-base values of 32 cases of severely acidotic acute abruptio placentae were statistically co...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(97)70187-x

    authors: Johnson JW,Richards DS

    更新日期:1997-08-01 00:00:00

  • Effect of oral contraceptives on rhythmic urinary metal excretion.

    abstract::Thirteen women, six of whom were using oral contraceptive agents, between the ages of 23 and 34 years, free from illness, and without a previous clinical history of menstrual abnormality, were studied with chronobiological methods for circadian (about 24 hour) patterns of metal and creatinine excretinine excretion. Ci...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(16)33342-7

    authors: Weinmann S,Dawson EB,Smolensky MH,Weisberg RF,Lane B,Bryan S

    更新日期:1976-04-01 00:00:00

  • Undiagnosed cases of fatal Clostridium-associated toxic shock in Californian women of childbearing age.

    abstract:OBJECTIVE:In 2005, 4 Clostridium sordellii-associated toxic shock fatalities were reported in young Californian women after medical abortions. The true incidence of this rare disease is unknown, and a population-based study has never been performed. Additional clostridia-associated deaths were sought to describe associ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2009.05.023

    authors: Ho CS,Bhatnagar J,Cohen AL,Hacker JK,Zane SB,Reagan S,Fischer M,Shieh WJ,Guarner J,Ahmad S,Zaki SR,McDonald LC

    更新日期:2009-11-01 00:00:00

  • Increasing NIH funding for academic departments of obstetrics and gynecology: a call to action.

    abstract::The National Institutes of Health funding for reproductive sciences research, specifically in academic departments of obstetrics and gynecology, is disproportionately low. Research is one of the most important pillars in advancing healthcare. Despite US Congress' vision in providing increased funding to the National I...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2020.03.022

    authors: Rice LW,Cedars MI,Sadovsky Y,Siddiqui NY,Teal SB,Wright JD,Zorbas A,Del Carmen MG

    更新日期:2020-07-01 00:00:00

  • Fetal renal volume assessment by three-dimensional ultrasonography.

    abstract:OBJECTIVE:This study was undertaken to measure fetal renal volume by means of three-dimensional ultrasonography and to use those data to establish the accurate constant and formula for fetal renal volume assessment with two-dimensional ultrasonography. STUDY DESIGN:Singleton fetuses between 15 and 40 weeks' gestation ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(00)70227-4

    authors: Hsieh YY,Chang CC,Lee CC,Tsai HD

    更新日期:2000-02-01 00:00:00

  • The efficacy of intrapartum electronic fetal monitoring.

    abstract::With basic methodologic criteria as a framework, this report assesses the quality of the seven randomized controlled clinical trials conducted in five countries to compare a policy of routine electronic fetal monitoring with a policy of fetal heart rate monitoring by auscultation. One trial found a statistically signi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-9378(87)90197-9

    authors: Thacker SB

    更新日期:1987-01-01 00:00:00

  • Human placental glucose uptake and transport are not altered by the oral antihyperglycemic agent metformin.

    abstract:OBJECTIVE:Our purpose was to determine whether the biguanide oral antihyperglycemic agent metformin increases human placental uptake and transport of glucose to the fetal circulation. STUDY DESIGN:The human single-cotyledon model was used to compare transport of tritiated glucose in the maternal to fetal direction in ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(97)70541-6

    authors: Elliott BD,Langer O,Schuessling F

    更新日期:1997-03-01 00:00:00

  • Oral contraceptives, clotting factors, and thrombosis.

    abstract::Oral contraceptives (OCs) raise the plasma levels of some clotting factors, especially factor VII. Until recently, however, there has been no evidence for a relationship between high levels of clotting factor and the onset of clinically manifest vascular disease. It has not been established, on a preliminary basis, th...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(16)32484-x

    authors: Meade TW

    更新日期:1982-03-15 00:00:00

  • Oxytocin enhances action potentials in pregnant human myometrium--a study with microelectrodes.

    abstract:OBJECTIVE:Our purpose was to quantitatively assess the effects of oxytocin on membrane properties in the pregnant human myometrium. STUDY DESIGN:Specimens were obtained from the lower uterine segment during cesarean section at term. Electrical activity was recorded from individual cells by a conventional microelectrod...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(97)70465-4

    authors: Nakao K,Inoue Y,Okabe K,Kawarabayashi T,Kitamura K

    更新日期:1997-07-01 00:00:00

  • Preeclampsia is not associated with altered platelet vasopressin binding and cytosolic Ca++ concentration.

    abstract:OBJECTIVES:Preeclampsia is an important cause of fetal and maternal morbidity and mortality. Recently it was described that platelet cytosolic Ca++ levels could be used to screen for preeclampsia. The current study investigated platelet arginine vasopressin receptor characteristics, platelet cytosolic Ca++ levels, plas...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(93)90276-o

    authors: van der Post JA,Konijnenberg A,Boer K,Schaap MC,van Boxtel CE,Sturk A,Boer GJ,Swaab DF

    更新日期:1993-11-01 00:00:00

  • Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin.

    abstract:OBJECTIVE:We studied the role of smooth muscle-relaxing prostacyclin and its endogenous antagonist, thromboxane A2, in preterm labor by assessing the urinary output of the breakdown products of prostacyclin (6-keto-prostaglandin F1 alpha and 2,3-dinor-6-keto-prostaglandin F1 alpha) and those of thromboxane A2 (thrombox...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(92)91851-z

    authors: Kurki T,Viinikka L,Ylikorkala O

    更新日期:1992-01-01 00:00:00

  • The treatment of premenstrual syndrome with preparations of Vitex agnus castus: a systematic review and meta-analysis.

    abstract:BACKGROUND:Premenstrual syndrome is characterized by the cyclic occurrence of physical, behavioral and psychological symptoms during the luteal phase of the menstrual cycle disappearing within a few days of the onset of menstruation. Generally symptoms are mild, but 5-8% of women suffer from severe PMS. Apart from conv...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ajog.2017.02.028

    authors: Verkaik S,Kamperman AM,van Westrhenen R,Schulte PFJ

    更新日期:2017-08-01 00:00:00

  • Maternal serum screening for fetal Down syndrome in the United States: a 1992 survey.

    abstract:OBJECTIVE:Our purpose was to determine the status of screening for fetal Down syndrome in the United States in 1992. STUDY DESIGN:Information was sought from laboratories participating in two proficiency testing programs. RESULTS:The 301 responding laboratories (98%) annually provided services to 2,113,000 pregnant w...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(93)90436-m

    authors: Palomaki GE,Knight GJ,McCarthy J,Haddow JE,Eckfeldt JH

    更新日期:1993-12-01 00:00:00

  • Percutaneous ultrasound-guided fetal blood sampling in the management of nonimmune hydrops fetalis.

    abstract::Nonimmune hydrops fetalis can be caused by fetal chromosomal, hematologic, cardiac, or infectious conditions. A fetal blood sample obtained from percutaneous ultrasound-guided fetal blood sampling can offer vital information about the underlying cause of nonimmune hydrops fetalis, and perinatal management can be plann...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(87)80343-5

    authors: Hsieh FJ,Chang FM,Ko TM,Chen HY

    更新日期:1987-07-01 00:00:00

  • Does maternal age at retrieval influence the implantation potential of euploid blastocysts?

    abstract:BACKGROUND:Age-related decline in reproductive potential is mainly due to the increased incidence of aneuploidy. Furthermore, 2 recent studies have shown that euploid embryos of older women may have a lower implantation potential compared to those of younger women, suggesting that aging might compromise embryos beyond ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2018.11.1103

    authors: Irani M,Zaninovic N,Rosenwaks Z,Xu K

    更新日期:2019-04-01 00:00:00

  • Progression of ultrasound findings of fetal syphilis after maternal treatment.

    abstract:OBJECTIVE:The purpose of this study was to evaluate ultrasound findings of fetal syphilis and to describe their progression after maternal treatment. STUDY DESIGN:This was a retrospective cohort study from September 1981 to June 2011 of seropositive women after 18 weeks of gestation who had an ultrasound before treatm...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2014.05.049

    authors: Rac MW,Bryant SN,McIntire DD,Cantey JB,Twickler DM,Wendel GD Jr,Sheffield JS

    更新日期:2014-10-01 00:00:00

  • Prostaglandins and abortion. II. Single extra-amniotic administration of 0.92 mg. of 15-methyl prostaglandin F2alpha in Hyskon for termination of pregnancies in weeks 10 to 20 of gestation: an international multicenter study. World Health Organization Tas

    abstract::In a multicenter comparative trial, 15-methyl prostaglandin F2alpha(PGF2alpha), 0.92 mg., was administered by extra-amniotic injection to 660 patients. Abortion of the fetus occurred within 24 hours in 479 patients (72.6 per cent) and within 36 hours in 530 patient (80.3 per cent). Abortion was complete in 31 per cent...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:1977-11-15 00:00:00

  • X-ray pelvimetry in a breech protocol: a comparison of digital radiography and conventional methods.

    abstract::X-ray evaluation of the pelvis plays a pivotal role in selecting term breech presentation for a possible trial of labor. Even minimal degrees of disproportion may have disastrous consequences for the aftercoming head. Our evaluation of x-ray pelvimetry by computerized tomography scanning suggests it is probably more a...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(85)90695-7

    authors: Gimovsky ML,Willard K,Neglio M,Howard T,Zerne S

    更新日期:1985-12-15 00:00:00

  • Immunohistochemical evidence for the interaction between levator ani and pudendal motor neurons in the coordination of pelvic floor and visceral activity in the squirrel monkey.

    abstract:OBJECTIVE:The purpose of this study was to characterize the spinal distribution of afferent and efferent pathways that innervate the levator ani (LA) muscle in the female squirrel monkey. STUDY DESIGN:Cholera toxin B (CTB) was injected unilaterally into the LA muscle of 5 monkeys to identify primary sensory neurons in...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2004.10.607

    authors: Pierce LM,Reyes M,Thor KB,Dolber PC,Bremer RE,Kuehl TJ,Coates KW

    更新日期:2005-05-01 00:00:00

  • Developing applications of prostaglandins in obstetrics and gynecology.

    abstract::Clinical research has shown that prostaglandins (PGs) play an important role in every phase of human reproduction. The logical consequence of early basic biological research into PGs is the current interest in clinical evaluation of PGs as agents to induce labor and abortion and to stimulate menstruation. This is a ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(72)90467-x

    authors: Hinman JW

    更新日期:1972-05-01 00:00:00

  • Use of cardiac index in pregnancy: is it justified?

    abstract:OBJECTIVE:The aim of this study was to test the hypothesis that standardization of cardiac output in pregnancy by correcting for body surface area, and thus obtaining cardiac index, is justified. STUDY DESIGN:Cardiac output was determined by thoracic electrical bioimpedance monitoring in 78 pregnant women; recordings ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(95)90367-4

    authors: van Oppen AC,van der Tweel I,Duvekot JJ,Bruinse HW

    更新日期:1995-09-01 00:00:00

  • Anatomic relationships of the pelvic autonomic nervous system in female cadavers: clinical applications to pelvic surgery.

    abstract:BACKGROUND:The integrity of the pelvic autonomic nervous system is essential for proper bowel, bladder, and sexual function. OBJECTIVE:The purpose of this study was to characterize the anatomic path of the pelvic autonomic system and to examine relationships to clinically useful landmarks. STUDY DESIGN:Detailed disse...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2016.12.002

    authors: Ripperda CM,Jackson LA,Phelan JN,Carrick KS,Corton MM

    更新日期:2017-04-01 00:00:00

  • Condom use and incident sexually transmitted infection after initiation of long-acting reversible contraception.

    abstract:BACKGROUND:Use of more effective contraception may lead to less condom use and increased incidence of sexually transmitted infection. OBJECTIVE:The objective of this study was to compare changes in condom use and incidence of sexually transmitted infection acquisition among new initiators of long-acting reversible con...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2017.09.009

    authors: McNicholas CP,Klugman JB,Zhao Q,Peipert JF

    更新日期:2017-12-01 00:00:00

  • Microarray technology in obstetrics and gynecology: a guide for clinicians.

    abstract::Microarrays can be constructed with dozens to millions of probes on their surface to allow high-throughput analyses of many biologic processes to be performed simultaneously on the same sample. Microarrays are now widely used for gene expression analysis, deoxyribonucleic acid resequencing, single-nucleotide polymorph...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ajog.2005.12.014

    authors: Ward K

    更新日期:2006-08-01 00:00:00

  • Neonatal outcome after indomethacin treatment for preterm labor.

    abstract::Forty-six infants exposed to indomethacin in utero for treatment for preterm labor were compared with infants from two control groups. In one control group the next consecutive patient treated with a tocolytic agent was used, and the other control group was formed by picking the next consecutive patient matched by ges...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(86)80012-6

    authors: Niebyl JR,Witter FR

    更新日期:1986-10-01 00:00:00

  • Cardiovascular effects of 6 months of hormone replacement therapy versus placebo: differences associated with years since menopause.

    abstract:OBJECTIVE:In response to post-Women's Health Initiative dialog regarding individualized hormone replacement therapy (HRT), this study evaluates cardiovascular and neuroendocrine effects of HRT versus placebo in postmenopausal women grouped according to time since menopause. STUDY DESIGN:Resting and stress blood pressu...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.ajog.2003.09.045

    authors: Brownley KA,Hinderliter AL,West SG,Grewen KM,Steege JF,Girdler SS,Light KC

    更新日期:2004-04-01 00:00:00

  • Elevated serum ferritin in the altered ferrokinetics of toxemia of pregnancy.

    abstract::The serum concentration of ferritin in 11 patients with toxemia of pregnancy was compared to that of normal women in the early third trimester of pregnancy and in labor at term. The mean concentration of ferritin for toxemic patients was 91.8 ng/ml compared to 18.4 ng/ml and 19.4 ng/ml for the two control groups, resp...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(82)90247-2

    authors: Entman SS,Richardson LD,Killam AP

    更新日期:1982-10-15 00:00:00

  • Risk during pregnancy--self-report versus medical record.

    abstract:OBJECTIVE:This study was undertaken to compare the frequencies with which physicians and patients report medical and behavioral risk factors during pregnancy, with particular attention to identification of women at risk for prenatal alcohol use. STUDY DESIGN:The sample included 278 women, drawn from a randomized trial...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2005.04.053

    authors: McNamara TK,Orav EJ,Wilkins-Haug L,Chang G

    更新日期:2005-12-01 00:00:00