Abstract：
:Report of a study of Rh antibody titers in the amniotic fluids from 42 Rh-negative sensitized pregnancies is presented. Amniocentesis was performed in the pregnant Rh-negative women having serum Rh antibody titers (indirect Coombs) ranging from 1/64 to 1/4,096. Spectrophotometric analysis was done on the antiRh-D titers. In order to predict the outcome of pregnancy based on the amniotic fluid Rh antibody content, all fetuses were divided into 3 categories. Those with titers of 1/4 or below should correspond to Category I; unaffected or mildly affected babies; those with titers of 1/8 to 1/16 should be in Category II or have moderate to severe disease; while fetuses with titers of 1/32 or above would be in Category III indicating very severe disease. Out of 18 cases with titers of 1/4 or below, 17 were unaffected or mildly affected. In 10 patients titers of 1/8 or 1/16 were observed as the highest titer. 8 infants in this group were moderately to severely affected. 14 cases were observed with titers of 1/32 or above and in 11 of them, the pregnancy outcome was a severely ill or dead infant. The other 3 cases in this group were babies with severe anemia who required 2 or 3 exchange transfusions. It was learned that the antibody titer of amniotic fluid of Rh-sensitized pregnancies can be used as a reliable index of the severity of hemolytic disease in the fetus.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
Usategui-Gomez M,Stearns SB,Toolan HWsubject
Has Abstractpub_date
1969-12-15 00:00:00pages
1238-46issue
8eissn
0002-9378issn
1097-6868pii
0002-9378(69)90297-Xjournal_volume
105pub_type
杂志文章abstract：:Based on epidemiologic data, women who take oral contraceptives seem to have an increased risk of developing thromboembolic disease. In order to explain this association, some studies have been undertaken to find abnormalities in the hemostasis system. Many conflicting test results have been reported, probably reflect...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/s0002-9378(16)32489-9
更新日期：1982-03-15 00:00:00
abstract：:Nifedipine is a calcium channel blocker that reduces blood pressure and increases renal blood flow. This double-blind investigation evaluated the effect of nifedipine in postpartum patients with severe preeclampsia. Thirty-one patients were randomized to receive either nifedipine (10 mg) or placebo every 4 hours begin...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0002-9378(90)91011-z
更新日期：1990-03-01 00:00:00
abstract：:Sacral neuromodulation with an implanted device is used in patients who experience urinary retention and malfunctioning overactive bladder where conservative treatment is not sufficient. The knowledge of its effect on pregnancy is not known. This article presents the case of a 34-year-old pregnant woman with an implan...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2014.04.015
更新日期：2014-07-01 00:00:00
abstract：:Placental pathology can be useful in a variety of ways including immediate diagnosis of important conditions affecting the mother or infant, identifying conditions that are likely to recur in subsequent pregnancies, separating clinical syndromes into distinct pathological phenotypes for further investigation, and unco...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.ajog.2015.05.056
更新日期：2015-10-01 00:00:00
abstract：:Previous investigations have shown that the human placenta is a complex organ with different zones, each with a unique morphology. These zonal morphologic difference have been related to a probable blood PO2 gradient operating in the intervillous space. This study describes zonal variations in the vertical plane of th...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(78)90007-8
更新日期：1978-04-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to estimate the outcomes of uterine embolization and hysterectomy for uterine leiomyomas. Study design This was a multicenter prospective study of patients who were treated with embolization (n=102 patients) and hysterectomy (n=50 patients) for leiomyomas. Changes in symptoms, co...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.ajog.2004.03.037
更新日期：2004-07-01 00:00:00
abstract：:A previous study reported frequent resistance of the cervix at 9 mm during dilation and interpreted the resistance as the beginning of a tear of the internal os. A more recent identical study did not indicate such tears. Measurement of the dilators revealed that the set used in the previous study had uneven increments...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(88)80157-1
更新日期：1988-10-01 00:00:00
abstract：OBJECTIVE:Because the diagnosis of postpartum hemorrhage (PPH) depends on the accoucheur's subjective estimate of blood loss and varies according to mode of delivery, we examined temporal trends in severe PPH, defined as PPH plus receipt of a blood transfusion, hysterectomy, and/or surgical repair of the uterus. STUDY...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2013.07.007
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to evaluate maternal alloimmunization to paternal leukocytes as a treatment for hemolytic disease of the fetus/newborn in a rabbit model. STUDY DESIGN:Twelve does and paired red blood cell-incompatible bucks underwent the experimental protocol. Fetal hematologic parameters that ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2002.126960
更新日期：2002-10-01 00:00:00
abstract：:The rate of cesarean delivery has become an important health care issue, and has attracted the attention of governments, professional organizations, health care administrators, clinicians, and patients. This has resulted in the generation of guidelines, clinical recommendations, and other documents aimed at increasing...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2016.04.021
更新日期：2016-10-01 00:00:00
abstract：:Grand multiparity has been considered to be a factor in maternal and neonatal morbidity. In addition, families with seven or more children have been associated with low socioeconomic status. To minimize the confounding effect of the socioeconomic status, the outcome of grand multiparity has been investigated in a most...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(88)90213-x
更新日期：1988-05-01 00:00:00
abstract：OBJECTIVE:Our purpose was to determine the effect of in utero exposure to indomethacin on the need for surgical closure of a patent ductus arteriosus (PDA). STUDY DESIGN:Perinatal variables were compared between infants at <32 weeks who required surgical closure of PDA after failed medical management and those who did...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2002.127464
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVE:Although the presence of psammoma bodies in cervical cytologic smears has been associated previously with gynecologic malignancies, the clinical significance of this finding in asymptomatic women who undergo routine cervical cytologic screening has not been well defined. STUDY DESIGN:For this retrospective c...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2003.392
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:Our objective was to ascertain long-term tolerability and effects of a novel, low-dosage continuous progestin-cyclic estrogen regimen on vasomotor flushing, vaginal bleeding patterns, bone density, and plasma lipoprotein lipids. STUDY DESIGN:Eighteen postmenopausal women with climacteric symptoms received lo...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(92)91842-x
更新日期：1992-01-01 00:00:00
abstract：:Denaturing gradient gel electrophoresis was used to identify single-base differences in the cytochrome P-450 21-hydroxylase (CYP21) genes of 132 unrelated control individuals and family members of three unrelated patients with 21-hydroxylase deficiency. The salt-wasting variety was caused by gene deletion and gene con...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(92)91857-7
更新日期：1992-01-01 00:00:00
abstract：:During a 20 month period, 110 women with gonococcal pelvic inflammatory disease an 165 women with uncomplicated gonorrhea were provided intensive case-finding services (interviewing of patients and tracing of contacts). Approximately three contacts per case were investigated, and 24.3% of the 859 male contacts were in...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(80)91116-3
更新日期：1980-12-01 00:00:00
abstract：OBJECTIVE:This study was undertaken to assess the value of minor ultrasonographic markers in predicting significant karyotypic abnormalities. STUDY DESIGN:A total of 2743 fetuses (14-24 weeks' gestation) prospectively underwent a detailed ultrasonographic survey before genetic amniocentesis. Criteria for 8 minor ultra...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(99)70322-4
更新日期：1999-10-01 00:00:00
abstract：OBJECTIVE:The objective of the study was to evaluate the efficacy and safety of global endometrial ablation in women with a history of cesarean delivery. STUDY DESIGN:We performed a historical cohort study of patients who underwent endometrial ablation for menorrhagia between 1998 and 2005. Outcome measures included a...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2011.06.106
更新日期：2011-11-01 00:00:00
abstract：:Experiments were performed in conscious rabbits to investigate when during pregnancy cardiac baroreceptor reflex gain decreases. A decrease in gain was first observed after 3 weeks of gestation (-34.1 +/- 4.9 to -15.7 +/- 3.1 beats/min/mm Hg, p < 0.05) and became more pronounced after 4 weeks (-30.2 +/- 4.7 to -8.6 +/...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(97)70571-4
更新日期：1997-03-01 00:00:00
abstract：:The effects of prolonged mild hypoxemia on the fetus have received little attention. We investigated the response to a decrease in fetal arterial Po2 of 5 mm Hg or less sustained for a period of 24 hours in the chronically instrumented fetal lamb. Hypoxemia was induced by an infusion of nitrogen via the maternal trach...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(87)80261-2
更新日期：1987-12-01 00:00:00
abstract：:The management of 430 diabetic pregnancies is presented. Our protocol emphasized "tight" metabolic control and assessment of fetal well-being by antepartum fetal heart rate testings and estriol levels. Spontaneous labor was allowed in uncomplicated Class A diabetic patients. Labor in complicated cases and insulin-depe...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(85)90341-2
更新日期：1985-12-01 00:00:00
abstract：OBJECTIVE:The purpose of this research was to test a widely publicized theory that nausea and vomiting of pregnancy protects women from ingesting certain vegetables and other foods that produce congenital anomalies and other adverse outcomes of pregnancy. STUDY DESIGN:The theory was tested with use of data on dietary ...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1016/s0002-9378(97)80032-4
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVE:In a seroepidemiologic study the effects of pregnancy and other factors on humoral response to human papillomavirus type 16 infection were examined. STUDY DESIGN:Multiple serum samples were taken at 3-month intervals for 15 months from 77 pregnant and 85 nonpregnant women. Serologic response to human papillo...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(98)80026-4
更新日期：1998-02-01 00:00:00
abstract：OBJECTIVE:Postpartum infections are polymicrobial and typically include Ureaplasma, an intracellular microbe that is treated by macrolides such as azithromycin. The aim of this study was to evaluate the perinatal pharmacokinetics of azithromycin after a single preincision dose before cesarean delivery. STUDY DESIGN:Th...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajog.2015.01.015
更新日期：2015-06-01 00:00:00
abstract：:Experiments were conducted with 11 chronically catheterized fetal sheep to determine the effects of norepinephrine on the distribution of umbilical venous blood through the ductus venosus, and within the fetal liver. An intraumbilical infusion of 1.1 microgram/kg/min of norepinephrine increased placental blood flow bu...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(80)90388-9
更新日期：1980-05-01 00:00:00
abstract：BACKGROUND:A growing literature suggests that minority races, particularly Black women, have a lower probability of live birth and higher risk of perinatal complications after autologous assisted reproductive technology. However, questions still remain as to whether these racial disparities have arisen because of assoc...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2020.09.013
更新日期：2020-09-12 00:00:00
abstract：OBJECTIVE:We sought to develop a valid, reliable assessment of intraoperative judgment by residents during gynecologic surgery based on Script Concordance Theory. STUDY DESIGN:This was a multicenter prospective study involving 5 obstetrics and gynecology residency programs. Surgeons from each site generated case scena...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajog.2010.04.010
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVE:Iron supplementation in pregnancy seems beneficial for neonatal/maternal outcomes, but it was associated with diabetes and hypertension in the general population. STUDY DESIGN:We investigated the association between iron supplementation during midpregnancy and metabolic/hypertensive abnormalities in 500 cons...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2009.04.049
更新日期：2009-08-01 00:00:00
abstract：:Vaginitis is one of the most common causes of patient visits to gynecologists, primary care providers, and urgent care centers. However, many women leave without a clear diagnosis or experience recurrent symptoms despite treatment. The 3 most common etiologies of vaginitis are trichomonas, bacterial vaginosis, and vul...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.ajog.2019.09.001
更新日期：2020-02-01 00:00:00
abstract：:Two infants, who presented at birth with isoimmune thrombocytopenic purpura, are the basis for this report. The problems confronting the physician in treating an affected infant, as well as in the management of subsequent pregnancies after an infant with isoimmunization has been delivered, are discussed. In view of th...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(76)90008-9
更新日期：1976-01-01 00:00:00
