Outcome of uterine embolization and hysterectomy for leiomyomas: results of a multicenter study.

Abstract:

OBJECTIVE:The purpose of this study was to estimate the outcomes of uterine embolization and hysterectomy for uterine leiomyomas. Study design This was a multicenter prospective study of patients who were treated with embolization (n=102 patients) and hysterectomy (n=50 patients) for leiomyomas. Changes in symptoms, complications, and quality of life were measured. The data analysis included linear and logistic regression, the Student t and paired t test, Fisher's exact test, and chi-squared test. RESULTS:For patients who underwent embolization, there were marked reductions in blood loss scores (P <.001) and menorrhagia questionnaire scores (P <.001) compared with baseline. At 12 months, a larger proportion of the patients who had undergone hysterectomy experienced improved pelvic pain (P=.021). Both groups had marked improvement in other symptoms and quality of life scores, with no difference between groups. Complications were more frequent in patients who underwent hysterectomy (50% vs 27.5%; P=.01). CONCLUSION:Both procedures substantially improved symptoms for most patients, with an advantage for hysterectomy at 12 months for pelvic pain. Serious complications were infrequent in both groups.

journal_name

Am J Obstet Gynecol

authors

Spies JB,Cooper JM,Worthington-Kirsch R,Lipman JC,Mills BB,Benenati JF

doi

10.1016/j.ajog.2004.03.037

subject

Has Abstract

pub_date

2004-07-01 00:00:00

pages

22-31

issue

1

eissn

0002-9378

issn

1097-6868

pii

S0002937804002832

journal_volume

191

pub_type

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