Recurrence of placental dysfunction disorders across generations.

Abstract:

OBJECTIVE:Knowledge about the causes of placental dysfunction disorders is limited. We performed an intergenerational study, focusing on the risks of placental dysfunction disorders in mothers and fathers who had been born small for gestational age (SGA). STUDY DESIGN:Using linked generational data from the Swedish Medical Birth Register from 1973-2006, we identified 321,383 mother-offspring units and 135,637 mother-father-offspring units. RESULTS:Compared with mothers who had not been born SGA, mothers who had been born SGA had the following adjusted odds ratios: late preeclampsia, 1.41 (95% confidence interval [CI], 1.26-1.57); early preeclampsia, 1.87 (95% CI, 1.38-2.35); placental abruption, 1.60 (95% CI, 1.23-2.09); spontaneous preterm birth, 1.11 (95% CI, 1.00-1.23); and stillbirth, 1.24 (95% CI, 0.84-1.82). Compared with parents who had not been born SGA, the risk of preeclampsia was more than 3-fold increased if both parents had been born SGA, whereas if only the mother had been born SGA, the corresponding risk was increased by only 50%. CONCLUSION:There is an intergenerational recurrence of placental dysfunction disorders on the maternal side and most likely also on the paternal side.

journal_name

Am J Obstet Gynecol

authors

Wikström AK,Svensson T,Kieler H,Cnattingius S

doi

10.1016/j.ajog.2011.05.009

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

454.e1-8

issue

5

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(11)00602-8

journal_volume

205

pub_type

杂志文章
  • Cardiovascular collapse during laparoscopy: a report of two cases.

    abstract::Cardiovascular collapse is a rare but serious complication of laparoscopy. Presented here are two cases of sudden cardiovascular collapse during laparoscopy. Possible causes include severe atypical vagal reactions and carbon dioxide embolism. Arterial blood gases indicated pulmonary vascular shunting. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(88)80044-9

    authors: Brantley JC 3rd,Riley PM

    更新日期:1988-09-01 00:00:00

  • Blunt vs. sharp uterine expansion at lower segment cesarean section delivery: a systematic review with metaanalysis.

    abstract:OBJECTIVE:Blunt vs sharp expansion of the uterine incision at cesarean delivery has been investigated as a technique primarily to reduce intraoperative blood loss. The objective of this systematic review was to compare the effects of either intervention on maternal outcomes. STUDY DESIGN:A systematic review with metaa...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ajog.2012.10.886

    authors: Xu LL,Chau AM,Zuschmann A

    更新日期:2013-01-01 00:00:00

  • Immunologic infertility. I. Cervical mucus antibodies and postcoital test.

    abstract::SAA and SIA were assayed in the sera of 172 infertile couples and in the CM of the women and 18 control subjects. Complete infertility evaluation was performed in all subjects except the controls. Results of these studies were correlated with PCT's. Sperm antibodies were detected in the CM of 25.6% of infertile women ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Moghissi KS,Sacco AG,Borin K

    更新日期:1980-04-01 00:00:00

  • Treatment of vaginal outflow tract obstruction in graft-versus-host reaction.

    abstract::We describe five patients with vaginal stenosis that was due to chronic graft-versus-host reaction after bone marrow transplantation. All patients underwent surgical procedures followed by local corticosteroids administration. Vaginal function was restored in all cases. This satisfactory result persists in the long te...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2003.262

    authors: Louis-Sylvestre C,Haddad B,Paniel BJ

    更新日期:2003-04-01 00:00:00

  • Adverse event reports after tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccines in pregnant women.

    abstract:OBJECTIVE:We sought to characterize reports to the Vaccine Adverse Event Reporting System (VAERS) of pregnant women who received tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap). STUDY DESIGN:We searched VAERS for reports of pregnant women who received Tdap from Jan. 1, 2005, through J...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2012.05.006

    authors: Zheteyeva YA,Moro PL,Tepper NK,Rasmussen SA,Barash FE,Revzina NV,Kissin D,Lewis PW,Yue X,Haber P,Tokars JI,Vellozzi C,Broder KR

    更新日期:2012-07-01 00:00:00

  • The management of acardiac twins: a conservative approach.

    abstract:OBJECTIVE:Optimal management of acardiac twin pregnancies is controversial. Data suggest a 50% mortality rate in the "pump" twin when the pregnancy is managed expectantly. Because of increased antenatal diagnosis, outcomes in expectantly managed cases may be better than reported. Our objective was to determine the outc...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/s0002-9378(03)00597-0

    authors: Sullivan AE,Varner MW,Ball RH,Jackson M,Silver RM

    更新日期:2003-11-01 00:00:00

  • Posttherapy residual disease associates with long-term survival after chemoradiation for bulky stage 1B cervical carcinoma: a Gynecologic Oncology Group study.

    abstract:OBJECTIVE:The objective of the study was to study posttherapy chemoradiation hysterectomy histology with long-term survival in bulky stage 1(B) cervical cancer patients. STUDY DESIGN:Gynecologic Oncology Group protocols 71 and 123 enrolled 464 patients randomly allocated to pelvic radiation (75 Gy, n = 291) plus hyste...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ajog.2010.05.005

    authors: Kunos C,Ali S,Abdul-Karim FW,Stehman FB,Waggoner S

    更新日期:2010-10-01 00:00:00

  • Bone mineral density during long-term prophylaxis with heparin in pregnancy.

    abstract:OBJECTIVE:We studied the effect of long-term heparin treatment on bone mass during pregnancy. STUDY DESIGN:Thromboprophylaxis with heparin was given to 39 women during pregnancy for a mean of 28 weeks and for an average of 6 weeks post partum. Bone mineral density measured with single-photon absorptiometry of the dist...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(94)70149-0

    authors: Dahlman TC,Sjöberg HE,Ringertz H

    更新日期:1994-05-01 00:00:00

  • Lack of relationship between prolactin and adrenal steroidogenesis in the ovine fetus.

    abstract::The role of fetal prolactin (PRL) as a fetal adrenotropic hormone was investigated in eight chronically catheterized fetal lambs. Catheters were placed for measurement of plasma prolactin (PRL), cortisol (F), dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and androstenedione (A). Daily (9 AM) ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(81)90320-3

    authors: Takahashi K,Auletta F,Tseng HY,Scommegna A,Burd LI

    更新日期:1981-02-15 00:00:00

  • Breech delivery: why the dilemma?

    abstract::A critical review of selected studies of breech delivery is presented with special attention to the statistical analysis of outcome for low birth weight and term breech delivery. Analysis of the data fails to support the routine use of cesarean birth for all cases of breech delivery except for those with hyperextensio...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(87)90193-1

    authors: Myers SA,Gleicher N

    更新日期:1987-01-01 00:00:00

  • Pitfalls in assessing chorioamnionicity: novel observations and literature review.

    abstract::Accurate diagnosis of chorioamnionicity in multiple pregnancies is the key to appropriate clinical management of multiple gestation. Although prenatal ultrasound assessment of chorioamnionicity is well established and highly accurate if performed in early pregnancy, exceptions and artifacts arise from anatomic variati...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ajog.2018.02.010

    authors: Lu J,Cheng YKY,Ting YH,Law KM,Leung TY

    更新日期:2018-09-01 00:00:00

  • Communicating contraceptive effectiveness: A randomized controlled trial to inform a World Health Organization family planning handbook.

    abstract:OBJECTIVE:The objective of the study was to compare 3 different approaches for increasing clients' understanding of contraceptive effectiveness. STUDY DESIGN:We randomized 900 reproductive-age women in India and Jamaica to 1 of 3 charts presenting pregnancy risk. RESULTS:The most important reason for choosing a contr...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ajog.2005.12.053

    authors: Steiner MJ,Trussell J,Mehta N,Condon S,Subramaniam S,Bourne D

    更新日期:2006-07-01 00:00:00

  • Prenatal diagnosis of 47,XXX.

    abstract::We report 2 cases of 47,XXX that were diagnosed prenatally and were screened positive for trisomy 21 by biochemical and ultrasound markers. These cases underline the importance of discussing the sex chromosome abnormalities during the genetic counseling after an abnormal triple screen test or ultrasound examination. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2004.12.037

    authors: Khoury-Collado F,Wehbeh AN,Fisher AJ,Bombard AT,Weiner Z

    更新日期:2005-05-01 00:00:00

  • The procoagulant activity of red blood cells from patients with severe preeclampsia.

    abstract:OBJECTIVE:Our purpose was to determine whether red blood cells from patients with severe preeclampsia may exhibit increased membrane exposure of procoagulant phospholipids (i.e., phosphatidylserine), which may initiate intravascular clotting and platelet activation. STUDY DESIGN:The study group comprised 28 women: 9 w...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(97)70100-5

    authors: Grisaru D,Zwang E,Peyser MR,Lessing JB,Eldor A

    更新日期:1997-12-01 00:00:00

  • Ovarian hyperandrogenism with normal and abnormal histologic findings of the ovaries.

    abstract::Thirty-one patients with clinical features of polycystic ovary syndrome (PCO) were studied to determine the correlation between biochemical and histologic findings. The biochemical features investigated were the effects of adrenocortical and ovarian suppression by dexamethasone and oral contraceptives (Ovulen) on plas...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(16)33087-3

    authors: Kim MH,Rosenfield RL,Hosseinian AH,Schneir HG

    更新日期:1979-06-15 00:00:00

  • Cesarean scar defect: a prospective study on risk factors.

    abstract:BACKGROUND:Cesarean scar defect (isthmocele) is a known complication after cesarean delivery. It has become more common due to a rising cesarean delivery rate. Isthmocele has been associated with various gynecological and obstetric problems such as uterine rupture, cesarean scar pregnancy, and bleeding disorders. OBJE...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2018.09.004

    authors: Antila-Långsjö RM,Mäenpää JU,Huhtala HS,Tomás EI,Staff SM

    更新日期:2018-11-01 00:00:00

  • Circulating maternal serum progesterone in high-risk pregnancies.

    abstract::Serum progesterone was measured by competitive protein-binding assay in 331 cases of normal pregnancy ranging from 6 to 42 weeks. Serial estimations of serum progesterone were performed in nine cases of severe hypertensive disorder of pregnancy, eight cases of twin pregnancy, three cases of twin pregnancy complicated ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(76)90859-0

    authors: Dawood MY

    更新日期:1976-07-15 00:00:00

  • Transvaginal ultrasonographic characterization of ovarian masses by means of color flow-directed Doppler measurements and a morphologic scoring system.

    abstract:OBJECTIVE:The aim of the study was to test the hypothesis that a combination of a previously devised morphologic scoring system and color flow-directed Doppler measurements would afford better discrimination between benign and malignant ovarian masses. STUDY DESIGN:The scoring system and color flow-directed Doppler me...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(12)90843-1

    authors: Timor-Tritsch LE,Lerner JP,Monteagudo A,Santos R

    更新日期:1993-03-01 00:00:00

  • Localized increase in nitric oxide production and the expression of nitric oxide synthase isoforms in rat uterus with experimental intrauterine infection.

    abstract:OBJECTIVE:We recently reported that nitric oxide was associated with increased mortality among pregnant rats with intrauterine infection. In our current study we investigated the expression of different isoforms of nitric oxide synthases and nitric oxide in the nonpregnant rat uterus with experimental intrauterine infe...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(99)70499-0

    authors: Fang L,Nowicki BJ,Dong YL,Yallampalli C

    更新日期:1999-09-01 00:00:00

  • The predictive value of quantitative fibronectin testing in combination with cervical length measurement in symptomatic women.

    abstract:BACKGROUND:The combination of the qualitative fetal fibronectin test and cervical length measurement has a high negative predictive value for preterm birth within 7 days; however, positive prediction is poor. A new bedside quantitative fetal fibronectin test showed potential additional value over the conventional quali...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2016.08.012

    authors: Bruijn MM,Kamphuis EI,Hoesli IM,Martinez de Tejada B,Loccufier AR,Kühnert M,Helmer H,Franz M,Porath MM,Oudijk MA,Jacquemyn Y,Schulzke SM,Vetter G,Hoste G,Vis JY,Kok M,Mol BW,van Baaren GJ

    更新日期:2016-12-01 00:00:00

  • Spontaneous uterine rupture at thirty-three weeks subsequent to previous superficial laparoscopic myomectomy.

    abstract::Obstetric uterine rupture has previously been reported after the laparoscopic removal of deep intramural myomas, but never has it been reported to follow the removal of superficial myomas. A 39-year-old primigravid woman with a history of a superficial subserous laparoscopic myomectomy was seen for acute abdominal sym...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(97)70110-8

    authors: Pelosi MA 3rd,Pelosi MA

    更新日期:1997-12-01 00:00:00

  • Immature (malignant) teratoma of the fallopian tube.

    abstract::Primary immature (malignant) teratoma of the fallopian tube is an extremely rare occurrence. We report such a case, which appears to be the third reported in the literature. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(89)80055-9

    authors: Baginski L,Yazigi R,Sandstad J

    更新日期:1989-03-01 00:00:00

  • Single-dose cephalosporin for prevention of major pelvic infection after vaginal hysterectomy: cefazolin versus cefoxitin versus cefotaxime.

    abstract::Antimicrobial overutilization accelerates the development of bacterial resistance. A prospective, randomized, blinded clinical trial of vaginal hysterectomy prophylaxis was designed to compare the efficacy, safety, and costs of cefazolin with those of cefoxitin and cefotaxime. Sixteen women (7.5%) developed febrile mo...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-9378(87)90144-x

    authors: Hemsell DL,Bawdon RE,Hemsell PG,Nobles BJ,Johnson ER,Heard MC

    更新日期:1987-05-01 00:00:00

  • Extremely elevated activity of serum alkaline phosphatase in gestational diabetes: a case report.

    abstract::We report a case of a 25-year-old pregnant woman with gestational diabetes and increased activity (25-fold) of placental isozyme of alkaline phosphatase. Abdominal ultrasonographic scan revealed no hepatobiliary disease. After delivery, the alkaline phosphatase level decreased but did not return to the reference range...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(03)00904-9

    authors: Wojcicka-Bentyn J,Czajkowski K,Sienko J,Grymowicz M,Bros M

    更新日期:2004-02-01 00:00:00

  • Clinical findings among young women with genital human papillomavirus infection.

    abstract:OBJECTIVE:The purpose of this study was to identify clinical signs and symptoms associated with detection of human papillomavirus (HPV) DNA in the female genital tract. STUDY DESIGN:A total of 516 university students (18 to 24 years old) enrolled in a cohort study that included the collection of genital specimens for ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2003.164

    authors: Mao C,Hughes JP,Kiviat N,Kuypers J,Lee SK,Adam DE,Koutsky LA

    更新日期:2003-03-01 00:00:00

  • The senior obstetrician requesting obstetric privileges.

    abstract::As the American physician workforce matures in age, senior physicians on the active clinical staff may become vulnerable to diminished professional performance. Many physicians compensate by using experiential rather than analytic methods to effectively solve clinical problems. Surgical expertise also may be at risk i...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ajog.2011.07.043

    authors: Porreco RP

    更新日期:2012-03-01 00:00:00

  • Stimulation of human fetuses with sound and vibration.

    abstract::Forty pregnant women between 30 and 42 weeks' gestational age were studied to examine the effects of external sound and vibration on the fetal heart rate. A significant increase in the mean duration and amplitude of the first acceleration after sound stimulus was found when these values were compared with the control ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(86)80037-0

    authors: Gagnon R,Patrick J,Foreman J,West R

    更新日期:1986-10-01 00:00:00

  • Changes in hemorheology with fetal intravascular transfusion.

    abstract:OBJECTIVE:Our aim was to determine the changes in fetal hemorheologic parameters caused by fetal intravascular transfusion for alloimmune anemia. STUDY DESIGN:Fetal blood samples were collected before and after 95 fetal transfusions in 31 women. Fetal hematocrit, whole-blood viscosity at a variety of shear rates, plas...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(94)70271-3

    authors: Welch R,Rampling MW,Anwar A,Talbert DG,Rodeck CH

    更新日期:1994-03-01 00:00:00

  • Efficacy of the fetal-pelvic index in patients requiring labor induction.

    abstract::The fetal-pelvic index is a recently described means of identifying the presence or absence of fetal-pelvic disproportion. In this follow-up study, the efficacy of the fetal-pelvic index was evaluated in 49 patients requiring labor induction and was compared with two other methods used to identify fetal-pelvic disprop...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(88)80021-8

    authors: Morgan MA,Thurnau GR

    更新日期:1988-09-01 00:00:00

  • Progesterone receptor polymorphisms and clinical response to 17-alpha-hydroxyprogesterone caproate.

    abstract:OBJECTIVE:Seventeen-alpha-hydroxyprogesterone caproate (17-OHPC) reduces recurrent preterm birth (PTB). We hypothesized that single nucleotide polymorphisms in the human progesterone receptor (PGR) affect response to 17-OHPC in the prevention of recurrent PTB. STUDY DESIGN:We conducted secondary analysis of a study of...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ajog.2011.03.048

    authors: Manuck TA,Lai Y,Meis PJ,Dombrowski MP,Sibai B,Spong CY,Rouse DJ,Durnwald CP,Caritis SN,Wapner RJ,Mercer BM,Ramin SM

    更新日期:2011-08-01 00:00:00