[Postoperative radiotherapy of the chest wall in patients with male breast cancer].

Abstract:

INTRODUCTION:We analysed our long-term results with postoperative radiotherapy of the chest wall in male breast cancer patients with respect to local control and survival. METHODS:Twenty-five patients with 26 histological proven carcinomas of the male breast underwent postoperative radiotherapy of the chest wall with (n = 15) or without regional lymphatics after mastectomy. Additionally 13 patients received adjuvant hormones and 3 patients adjuvant chemotherapy. Median age at treatment was 62.2 years (45.9-78.5 years). Median follow-up was 15.3 years (7.7-27.5 years). RESULTS:Overall survival after radiotherapy was 28 %, disease-specific survival was 64 %. Actuarial 3-, 5- and 10-year survival was 72 %, 56 % and 35 %. Median survival time was 6.1 years. Actuarial progression-free survival was 80 %, 52 % and 43 % after 3, 5 and 10 years, respectively. Local tumor control was 92 % (24 / 26). Survival was significantly affected by the presence of lymph node metastases (p < 0.01) and localisation of the tumor in the right breast (p < 0.04). CONCLUSION:Postoperative radiotherapy is an important part of the management of male breast cancer to improve local control and progression-free survival. The presence of lymph node metastases significantly impairs survival.

journal_name

Zentralbl Chir

authors

Zabel-du Bois A,Milker-Zabel S,Wannenmacher M,Debus J

doi

10.1055/s-2007-981268

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

391-5

issue

5

eissn

0044-409X

issn

1438-9592

journal_volume

132

pub_type

杂志文章
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  • [Analysis of Survival Time and Other Event Times - What Does the Surgeon Need to Know?].

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  • [The subjective element in transplantation medicine. The importance of psychosocial indicators in transplantation and their effect on the quality of life].

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