Abstract：
BACKGROUND:Survival time is an important parameter to investigate therapeutic measures. It plays a crucial role in study concepts, data analyses as well as publications. AIM:The aim of this study was to emphasise essential points, which need to be taken into account to (i) gain resilient results of survival time analysis and (ii) appropriately evaluate scientific reports. Corner Points/Main Statements: (i) The main analytical methods are Kaplan-Meier procedure to estimate survival time curves, the log rank test to compare two or more survival curves from independent samples and Cox regression for comparisons under simultaneous consideration of several influencing factors. (ii) Dependent relationships between survival and censoring probabilities may falsify these statistical procedures. (iii) For several end points, which need to be differentiated (such as death, progression etc.), and for interdependent sample elements, extended statistical procedures such as competing risk analyses or extended Cox regression models are available. CONCLUSION:Survival time analysis can be considered as being extraordinarily important for evaluation of data obtained in therapeutic studies. For the academic and publishing physician, in particular, for the clinical surgeon, a basic understanding of these methodological aspects in statistics is indispensable.
journal_name
Zentralbl Chirjournal_title
Zentralblatt fur Chirurgieauthors
Kropf S,Meyer F,Glimm Edoi
10.1055/s-0034-1383077subject
Has Abstractpub_date
2016-08-01 00:00:00pages
383-9issue
4eissn
0044-409Xissn
1438-9592journal_volume
141pub_type
杂志文章,评审abstract：:The hormonally induced changes in the breast during pregnancy make the diagnosis of breast cancer difficult. Furthermore, examinations during pregnancy tend to concentrate only on the pregnancy itself. In this report the clinical, pathological and immunohistochemical results from 7 patients with breast cancer during p...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：AIMS:Laparoscopic splenectomy has been established as standard procedure for elective splenectomy and is performed for a variety of haematological diseases. However, different techniques have been used and a four- to five trocar technique is applied in most instances. We report our experience with a three-trocar techni...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2004-820359
更新日期：2004-10-01 00:00:00
abstract：:This clinical trial aimed to prospectively investigate the morphological structure of infrarenal abdominal aortic aneurysms (AAA) to establish a valid dataset in the preoperative assessment supporting either the conventional or endovascular (TPEG) surgical approach. Regarding both the general feasibility testing and s...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:237 Shouldice operations with resection of the cremaster muscle from the Department of Surgery of the RWT University of Aachen were compared with 153 Shouldice repairs without resection of the cremaster muscle from the Department of Surgery of the Elizabeth Hospital in Essen. The aim of this prospective controlled tri...
journal_title：Zentralblatt fur Chirurgie
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1991-01-01 00:00:00
abstract：:Aneurysms of the subclavian artery are extremely rare and most commonly caused by arteriosclerosis, trauma or thoracic outlet syndrome. Less frequently seen causes also include syphilis, cystic media necrosis or tuberculosis or congenital anomalies. The presence of a subclavian aneurysm can give rise to various sympto...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:The number of patients with a diagnosis of cancer is alarming: according to new figures from the Robert Koch Institute about 435 000 patients are diagnosed annually in Germany. 210 000 patients die annually of this diagnosis. Even if no significant progress in prevention has been achieved, in 2020 about 25 % more case...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0031-1283923
更新日期：2013-02-01 00:00:00
abstract：:Extended liver resections are associated with the risk of postoperative liver dysfunction up to liver failure. For this reason, prior to extended liver resections patients are conditioned in multi-modal therapy regimes. Portal vein embolisation is an essential part of such a multi-modal therapy. The aim of this interv...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0032-1328350
更新日期：2013-08-01 00:00:00
abstract：:The electrico-acoustical auscultation of intestinal sounds permits a continuous recording, documentation and evaluation of the intestinal motility to be made. Temporal course and duration of the sounds as well as their amplitude as a measure of their intensity are criteria for the diagnosis. The frequency-analysis of ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Out of a total of 3347 patients operated on for acute appendicitis 125 were found to be infected with Yersinia enterocolitica. Histological examination revealed a catarrhal-purulent inflammation or a phlegmonous-gangrenous inflammation in 58,6%. This detection of Yersinia enterocolitica does not justify the omission t...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Etiology, symptoms and diagnosis of Crohn's disease are described in a clinical study based on 37 patients. Drug therapy, surgery and their indications are discussed. Among 37 patients suffering from Crohn's disease of the complicated chronic type postoperative lethality amounted to 8.1%, the rate of complications cam...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:In parenteral nutrition a distinction can be made between hypocaloric, normocaloric, and hypercaloric forms, depending on the amount of energy supply. Hypocaloric parenteral nutrition has been specifically adjusted to the conditions of postoperative metabolism. Doses between 1.2 g and 1.5 g/kg body weight/d of amino a...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:In a 19 year old man with a single kidney the development of a large Douglas' abscess was followed by anuria; The various causes are discussed. It is resonable to assume, that the obstruction resulted from longitudinal tension of the ureter over the iliace vessels (iliac sign). ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：BACKGROUND:Since 1983 gastric banding has become a proven operative method, which reduces effectively excess weight in morbid obesity. Gastric banding has been popularized as a minimally invasive, completely reversible surgical treatment for morbid obesity. We report here our 4 year experiences of gastric banding with ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2000-10650
更新日期：2000-01-01 00:00:00
abstract：:Different causes, for example posttraumatic and postoperative complications, can lead to an elevated intra-abdominal pressure. Increased intraabdominal pressure effects cardiovascular, pulmonary and renal systems. The abdominal compartment syndrome can be defined as organ failure caused by an increased intra-abdominal...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2001-16568
更新日期：2001-08-01 00:00:00
abstract：:Modern oncological liver surgery continues to push the limits of resectability by incorporating an array of new developments in the fields of surgery, anaesthesia and intensive care, oncology, radiology and transplantation medicine. New criteria for determining the resectability of primary and secondary liver tumours ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0033-1350815
更新日期：2014-04-01 00:00:00
abstract：:Surgical tactics for the teatment of complicated diverticulitis are in constant evolution and remain a subject of controversy. Amongst 53 patients operated on for complicated sigmoid diverticulits over a 10 year period in our hospital, 29 underwent a Hartmann's procedure (3 Hinchey's stage II, 19 stage III and 7 stage...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:Application of a LapSim-training model in the Students' Skills Lab as well as the objective evaluation of stress in a virtual operating room scenario offer new perspectives in laparoscopic simulation. METHODS:In a Students' Skills Lab , assessment of learning curves of laparoscopic basic skills and complex ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2008-1004744
更新日期：2008-06-01 00:00:00
abstract：:Anaesthesia was applied to 1,036 patients for diagnostic or therapeutic knee-joint arthroscopy, between 1983 and 1985. Different indications for general and regional anaesthesia, setbacks of spinal anaesthesia, and advantages likely to result from combined use of peridural anaesthesia and peridural analgesia are discu...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:VARY operations were performed at the authors' hospital on 25 patients for duodenal ulcer and on two patients for gastric ulcer, between May 1984 and January 1987. A postoperative complication was recorded from one patient only, that is bleeding of the anastomosis on the first postoperative day. All patients underwent...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:In 27 patients with refluxoesophagitis the resting LES-pressure was approximatly 80% lower than in 12 patients with asymptomatic hiatal hernia and 15 controls. All patients in the first group were operated on and 21 fundoplications (Nissen) and 6 anterior plications (Dor) were performed. The postiperativ LES-pressures...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:Following a short representation of etiology, morphology and classification of cysts of trachea the symptoms, diagnosis and therapy were described. 7 cases of the own patients material in 27 years are presented extensively. ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:To review the endogenous alterations generating critical illness in bowel obstruction. DATA SOURCES:Own experimental and clinical investigations and relevant articles published in international literature. DATA SYNTHESIS AND CONCLUSIONS:Large bowel obstruction is mostly confined to the colon. Passive dilata...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1998-01-01 00:00:00
abstract：:A new technique for breast imaging is presented. This technique combines radiographic mammography directly with automated ultrasound. The combined examination, which is performed without decompression of the breast, yields the conventional mammography films as well as a complete set of B-mode scans and ultrasound proj...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Lung cancer is one of the leading causes of death in Europe and the USA. A relatively good prognosis is limited to those patients in whom the tumor is detected at an early stage. As clinical symptoms of lung cancer are a late finding in the natural course of the disease, most of the patients are diagnosed at an advanc...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0033-1350855
更新日期：2013-10-01 00:00:00
abstract：:Regional chemotherapy offers a means to enhance the local efficacy of an otherwise ineffective systemic chemotherapy. The regional concentration advantage of a drug is proportional to its total body clearance and inversely proportional to the blood flow through the organ. Regional infusion of adriamycin, cisplatin, me...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:Recurrent gastroesophageal reflux symptoms in adolescents and young adults who underwent fundoplication in childhood present a technical challenge for the surgeon. The distal oesophagus and hiatus are difficult to access by laparotomy, the anatomy is modified by the primary procedure, and there are often den...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/a-1137-0128
更新日期：2020-12-01 00:00:00
abstract：:This article describes problems some surgeons of Dresden were confronted with in the time between 1750 and 1850. These surgeons present the transition of the 'Age of Enlightment' and the period of sciences. Special achievements are mentioned: Hedenus as the founder of the modern surgery in Dresden and as a pioneer in ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 历史文章,杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Biliary tract injury, although uncommon, is the most feared complication of laparoscopic cholecystectomy. Early identification or exclusion of such injury is essential for successful management. Over a two year period (1995-1996) twenty-one from a total of 413 ERCPs in this Surgical Endoscopy Unit were performed becau...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:Due to uncontrolled activation of digestive enzymes produced within the pancreas, acute pancreatitis is a disease with a great potential for complications and variable course. Since the pathophysiological steps of human pancreatitis can only be inadequately investigated, various animal models were establishe...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-0032-1328099
更新日期：2013-08-01 00:00:00
abstract：:Treatment was applied to 181 patients for acute pancreatitis at the Surgical Department of Friedrichshain Local Hospital, between December 1, 1985 and October 30, 1987. Ninety-two of these patients were in Stage I according to Kümmerle-Hollender, 62 in Stage II, and 27 in Stage III. Operations were performed on 57 pat...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
