[Lung cancer screening - where are we in 2013?].

Abstract:

:Lung cancer is one of the leading causes of death in Europe and the USA. A relatively good prognosis is limited to those patients in whom the tumor is detected at an early stage. As clinical symptoms of lung cancer are a late finding in the natural course of the disease, most of the patients are diagnosed at an advanced tumor stage when palliative care remains the only therapeutic option. For this reason, early diagnosis of lung cancer might save lives. The National Lung Screening Trial (NLST), in the U. S. A., provided evidence that screening with low-dose CT (LD-CT) is able to reduce lung cancer mortality by 20.0 %. The encouraging results of the NLST, however, could not be confirmed by the preliminary results of ongoing European trials. Even if the European trials are able to confirm a reduction in lung cancer mortality by LD-CT, a number of important questions must be answered before the implementation of nationwide screening programs. First of all, the population that might benefit from CT lung cancer screening has to be defined precisely. Furthermore, guidelines have to be established about how to manage screening participants with detected lung nodules, as the vast majority of these pulmonary nodules will prove to be benign. This review article summarizes the results of the NLST and the initial data from the European screening trials, and will discuss some of the major open questions in lung cancer screening with CT.

journal_name

Zentralbl Chir

authors

Prosch H,Mostbeck G

doi

10.1055/s-0033-1350855

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

S11-5

eissn

0044-409X

issn

1438-9592

journal_volume

138 Suppl 1

pub_type

杂志文章,评审
  • [Management of Complications of Pancreatic Anastomoses].

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    authors: Weber GF,Schmid A,Uder M,Grützmann R

    更新日期:2018-06-01 00:00:00

  • [Effectiveness of conservative treatment following distal radius epiphyses injuries].

    abstract::From 1966 to 1978, 122 infants and children suffering from injuries of the distal radial epiphysis were treated by reposition and repeated reposition. 68 of them were followed-up from 2 to 13 years later. In most cases spontaneous correction of remaining deformities by growth could be demonstrated. This remodelling of...

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    doi:

    authors: Ansorg P,Graner G

    更新日期:1985-01-01 00:00:00

  • [Truth and truthfulness in philosophy].

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    doi:10.1055/s-2000-10062

    authors: Siep L

    更新日期:2000-01-01 00:00:00

  • [Diagnostics and therapy of benign bone tumours (author's transl)].

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    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Knoch HG,Dominok GW

    更新日期:1978-01-01 00:00:00

  • [Investigations on the incidence of Yersinia enterocolitica - infections in the various forms of appendicitis, cholelithiasis, and goitre (author's transl)].

    abstract::Out of a total of 3347 patients operated on for acute appendicitis 125 were found to be infected with Yersinia enterocolitica. Histological examination revealed a catarrhal-purulent inflammation or a phlegmonous-gangrenous inflammation in 58,6%. This detection of Yersinia enterocolitica does not justify the omission t...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Bellmann A,Bellmann KP

    更新日期:1980-01-01 00:00:00

  • [Biliary endo-to-end anastomosis with extramucosal titanium clips. Initial results of a new technique].

    abstract:BACKGROUND:Bile duct anastomoses are still associated with a high failure rate. Although following iatrogenic bile duct transection only a positive selected group of patients get a primary end-to-end reconstruction, long-term results demonstrate an incidence of postoperative strictures up to 78%. Also in orthotopic liv...

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    pub_type: 杂志文章

    doi:10.1055/s-2000-10077

    authors: Birth M,Gerberding J,Markert U,Wohlschläger C,Brugmans F,Bruch HP

    更新日期:2000-01-01 00:00:00

  • [Foot salvage in diabetic gangrene].

    abstract:UNLABELLED:In 35 patients with diabetic gangrene, amputation above the ankle (n = 18) or below the ankle (n = 17) was planned by nonspecialised general surgical departments or practicing surgeons. Prior to the operation, these patients presented to a specialised diabetic foot clinic; their clinical courses were analyse...

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    pub_type: 杂志文章

    doi:

    authors: Jung V

    更新日期:1996-01-01 00:00:00

  • [Value of electromyography in diagnosis of incontinence].

    abstract::Electromyography (EMG) of the pelvic floor musculature is only carried out as a routine method in few clinics. There is a lack of standard patient groups and, correspondingly, standardized values do not exist. Close cooperation between proctologists and neurologists is the exception. Some surgeons use the EMG to evalu...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:

    authors: Jost WH

    更新日期:1996-01-01 00:00:00

  • [Laparoscopic-assisted mobilisation and resection of a sacrococcygeal teratoma Altman type III].

    abstract::Objective This video is a step-by-step illustration of the laparoscopic-assisted mobilisation and resection of a sacrococcygeal teratoma Altman type III. Indication Laparoscopic supralevatory tumour mobilisation is an established method in selected centres and can be the initial step in approaching sacrococcygeal tera...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0043-100015

    authors: Gödeke J,Engel V,Münsterer O

    更新日期:2017-06-01 00:00:00

  • [Crossectomy in ascending superficial thrombophlebitis of the leg veins].

    abstract::Ascending thrombophlebitis of the superficial leg veins is known to propagate into the deep leg veins and to embolize. In a prospective study we followed up 44 patients with sonographically diagnosed ascending thrombophlebitis into the deep veins (V. saphena magna n = 40, V. saphena parva n = 4). In 15 of 44 cases (34...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Kock HJ,Krause U,Albrecht KH,van der Laan E,Rudofsky G,Eigler FW

    更新日期:1997-01-01 00:00:00

  • [Pattern of prehension in patients with high cervical injuries (author's transl)].

    abstract::After explaining the tertiary patterns of prehension the possibilities of restoring prehensile function in patients after high cervical spinal injury (C4-C6) by means of orthotics or operation are discussed. Absolute indication for the application of electrical orthotics in patients with complete spinal cord injuries ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Terbizan A

    更新日期:1976-01-01 00:00:00

  • [Indications and limits of thoracoscopy in surgical diagnosis and therapy of lung diseases].

    abstract::Thoracoscopy is an invasive form of endoscopy which, however, can be performed with the patient in local anaesthesia. Hence, when it comes to patients, for example, in somewhat advanced age and thus with the surgical risk clearly increased, it can be used as the smallest possible intervention to clear up causes of eff...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Elfeldt R,Schröder D,Beske C

    更新日期:1989-01-01 00:00:00

  • [Explorative laparotomy and splenectomy for staging Hodgkin's disease in children (author's transl)].

    abstract::We recommend explorative laparotomy with splenectomy in the field of Hodgkin's lymphoma even in childhood. Operation is an early therapeutic and diagnostic method enabling further treatment to be made in relation to the stages of the disease. A chance of better survival seems to exist in children with Hodgkin's diseas...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Blau HJ

    更新日期:1977-01-01 00:00:00

  • [Change in concept--from vascular centre to interdisciplinary organ-oriented clinic for vascular medicine].

    abstract::Demographic developments have led to an exponential increase of cardiovascular illness. Additionally, the technical development of conservative and invasive treatment modalities has added to an increase of differentiated therapy. The development of vascular centres led to optimised processes in diagnostic and therapy ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1271602

    authors: Diener H,Larena-Avellaneda A,Koelbel T,Tato F,Debus S

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  • [Hiatal hernia; 359 cases. Late results].

    abstract::From 1948 to 1977 359 patients suffering from oesophageal reflux disorders or the hiatus-hernia-complex underwent surgery at the I. Surgical clinic of the Medical Faculty Palacky-Univ. in Olomouc. In the group of 50 patients with simple paraaesophageal hernias the operative mortality came up to 4.0%. The mortality rat...

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    pub_type: 杂志文章

    doi:

    authors: Serý Z,Duda M,Rocek V

    更新日期:1981-01-01 00:00:00

  • Phylloides tumours of the breast. A clinicopathologic study of 19 cases.

    abstract::During a period of 29 years (1960-1989), 19 patients with benign (15 cases) or malignant (4 cases) phylloides tumours were seen at the Surgical Clinic of Fundeni Hospital. Fourteen patients were followed up for a period of 2 to 21 years (mean 9.3 years). Two patients with benign tumours developed malignant recurrences...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Popescu I,Serbănescu M,Ivăşchescu C

    更新日期:1991-01-01 00:00:00

  • [Extrahepatic cholangiocarcinoma: current state of palliation therapy].

    abstract:INTRODUCTION:Decompression of bile ducts is the priority objective in the non-curative stage of hilar cholangiocarcinoma. Only this will prevent or slow down infectious complications and secondary biliary cirrhosis thereby sustaining the quality of life. KEY STATEMENTS: At present, photodynamic therapy combined with in...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1283917

    authors: Wolkersdörfer GW,Berr F,Nawara C,Emmanuel K

    更新日期:2012-12-01 00:00:00

  • [Comparison of the Masaoka-Koga Classification with the New TNM Staging of the IASLC/ITMIG for Thymoma and Thymic Carcinoma].

    abstract:BACKGROUND:The Masaoka-Koga classification describes the extent and spread of thymic epithelial malignancies. The objective of this study was to evaluate the Masaoka-Koga and the new TNM-staging system regarding differences in stage distributions, clinical implementation and therapeutic consequences. METHODS:Retrospec...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:10.1055/a-0606-5603

    authors: Ried M,Eicher MM,Neu R,Kraus D,Inderhees S,Marx A,Hofmann HS

    更新日期:2018-08-01 00:00:00

  • [Role of vacuum therapy in the management of the septic abdomen].

    abstract::Progress in intensive care medicine contributed substantially in lowering the mortality rate of patients suffering from diffuse secondary peritonitis. In the medical care of patients presenting a septic abdomen the persisting septic focus is one of the greatest problems. This is associated with other problems like tem...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:10.1055/s-2006-921512

    authors: Weidenhagen R,Grützner KU,Kopp R,Spelsberg FW,Jauch KW

    更新日期:2006-04-01 00:00:00

  • [Liver rupture in peliosis hepatis].

    abstract::A 44-year old woman had pain in the epigastric region under the thorax aperture on the left side 6 weeks prior to admission. Her doctor had prescribed Rewodina and Myocuran without success. Then she suffered circulatory collapse twice. Upon hospitalization, she experienced colicky upper abdominal pain and vomiting....

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Adam G,Lesser T,Neumann R

    更新日期:1991-01-01 00:00:00

  • [Creation of centres in high-volume hospitals -- promotor of communication].

    abstract::The number of patients with a diagnosis of cancer is alarming: according to new figures from the Robert Koch Institute about 435 000 patients are diagnosed annually in Germany. 210 000 patients die annually of this diagnosis. Even if no significant progress in prevention has been achieved, in 2020 about 25 % more case...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1283923

    authors: Möbius C,Schumacher G

    更新日期:2013-02-01 00:00:00

  • [Injuries of the knee joint (author's transl)].

    abstract::Immediate operative reconstruction of ligament injuries of the knee joint is recommended for the performance age. The optimal operation time is within 24 hours after the accident, it should be done within 72 hours. The important advantage of this early operation in comparison to a non-operative treatment is the possib...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Franke K

    更新日期:1977-01-01 00:00:00

  • [Avoidance of complications during Kimray-Greenfield filter implantation].

    abstract::In 9 out of 24 cases we experienced complications when implanting the Kimray-Greenfield-Filter. As a result of this the introduction of this filter is now performed by a guide wire. To obtain maximum results the introducer and the filter itself should be improved. ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Bisler H,Clemens S,Teubner K,Alemany J

    更新日期:1983-01-01 00:00:00

  • [Primary hemiarthroplasty after complex fracture of the humeral head--functional late results].

    abstract:UNLABELLED:Treatment of complex fractures of the humeral head remains an obviously unsolved problem. Under consideration of the problems of head preserving methods, the development of the last years tended towards the hemiprosthetic replacement. As the discussion about the methods and implants continues to be controver...

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    doi:10.1055/s-2003-37766

    authors: Kollig E,Kutscha-Lissberg F,Roetman B,Mielke E,Muhr G,Hahn MP

    更新日期:2003-02-01 00:00:00

  • [Effect of lymph node dissection on prognosis of colon carcinoma].

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    pub_type: 杂志文章

    doi:

    authors: Klupp J,Engels S,Junginger T

    更新日期:1995-01-01 00:00:00

  • [Problematic aspects of the Structural Health Regulation and minimal invasive surgery].

    abstract::Decisions in surgery will have to consider economic obligations more than ever before. Consequences are evident: the assessment of surgical efficiency will be insufficient when only considering the accuracy and results of a clinical study. We actually will have to document, moreover, the economic impact of therapeutic...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Kunz E

    更新日期:1997-01-01 00:00:00

  • [Results of the surgical treatment of ankle joint fractures].

    abstract::Surgical treatment was applied to 74 cases of ankle joint fractures at the author's hospital, between 1979 and 1984. Follow-up checks were made on 59 patients, within one to seven years from surgery. Luxation fractures accounted for 39 per cent. The rates of wound edge necrosis and bone infection were three per cent e...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Langenberg R

    更新日期:1986-01-01 00:00:00

  • [Tube obstruction in operation of esophageal atresia. Brief review of intraoperative complications based on a case report].

    abstract::In this case report we discuss the anaesthetic management of newborns with esophageal atresia classified as Vogt III b. This type is characterised by an upper esophageal pouch which ends blindly and a distal tracheoesophageal fistula. Commonly associated diseases are cardiac, renal, vertebral and anal anomalies. The m...

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    pub_type: 杂志文章,评审

    doi:

    authors: Bartz HJ,Tonner PH,Kluth D,Straub U,Scholz J

    更新日期:2000-01-01 00:00:00

  • [Dorsal double plating for fractures of the distal radius--a biomechanical concept and clinical experience].

    abstract::This article describes the anatomical and biomechanical rationale for stable internal fixation of distal radius fractures using a dorsal approach. The three column biomechanical model is illustrated. Advances in the understanding of the anatomy, the biomechanical model of the three columns and our clinical experience ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:10.1055/s-2003-44839

    authors: Rikli DA,Regazzoni P,Babst R

    更新日期:2003-12-01 00:00:00

  • [Changes in colitis surgery. II: Corrective interventions and conversion operations].

    abstract::Over a period of 9 years in 48 patients already operated on for ulcerative colitis secondary surgical interventions had to be planned. 25 patients had an ileostomy (IS), 10 a Kock-pouch (KP), 11 an ileoanal pouch (IAP) and 2 an ileorectal anastomosis (IRA). Whereas in 4 patients only the subjective wish for another pr...

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    pub_type: 杂志文章

    doi:

    authors: Kreissler-Haag D,Haberer M,Feifel G,Ecker KW

    更新日期:1998-01-01 00:00:00