Abstract:
INTRODUCTION:Interstitial lung diseases (ILD) in systemic sclerosis (SSc) are mainly encountered in patients with diffuse disease although they may occur less frequently in patients with limited cutaneous disease. BACKGROUND:In SSc early detection of ILD should be achieved by high resolution computed tomography and pulmonary function tests, including measurement of DLCO. In total up to 75% of patients with SSc develop ILD but it is progressive in only a minority of patients. Unlike idiopathic ILD, SSc associated ILD corresponds to non-specific interstitial pneumonia rather than usual interstitial pneumonia in the majority of cases. This explains the better prognosis of SSc associated ILD compared with idiopathic ILD. Nevertheless ILD represents one of the two main causes of death in SSc. VIEWPOINT:The treatment of SSc associated ILD is not well established. Anti-fibrosing treatments have failed to demonstrate benefit and cyclophosphamide, which has been used for about 15 years in the treatment of this condition, has recently been evaluated in two prospective randomised studies which showed a significant but modest effect on respiratory function. CONCLUSION:A subgroup of patients with rapidly progressive ILD might benefit from pulsed intravenous cyclophosphamide combined with prednisone 15 mg daily, but this remains to be confirmed.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Mouthon L,Berezné A,Brauner M,Kambouchner M,Guillevin L,Valeyre Ddoi
10.1016/s0761-8425(07)92767-9subject
Has Abstractpub_date
2007-10-01 00:00:00pages
1035-46issue
8eissn
0761-8425issn
1776-2588pii
MDOI-RMRF-10-2007-24-8-0761-8425-101019-20072013journal_volume
24pub_type
杂志文章,评审abstract::Total lung capacity (TLC) and residual volume (RV) estimations were obtained from single-breath nitrogen washouts in 96 male and 77 female healthy never-smokers with normal spirometry from a non-polluted rural area in north-east France. TLC depended on height (both sexes) and diminished slightly with age in males, wit...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:To analyze experimentation with and use of e-cigarette by middle school and high school students in Paris. METHOD:Since 2012, questions about e-cigarette use have been included in the cross-sectional survey on tobacco that is administered annually since 1991 by the Paris sans tabac association. Overall, 2% ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2015.05.010
更新日期:2016-03-01 00:00:00
abstract::Thrombocytopenia induced by rifampicin in the absence of prior sensitization is exceptional, especially when it occurs in a patient without risk factors. We report the case of a patient aged 25 years with no past history of medical, surgical or knowledge of having taken rifampicin previously, who was hospitalized for ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2013.03.009
更新日期:2013-11-01 00:00:00
abstract::The real cost of medical consumption was compared with the proportion of medication consumption of (the) GHM n(o) 681 (homogeneous group of patients, chemotherapy for cancer in day care) in the French case mix system (PMSI). For those patients in our thoracic oncology unit (Sainte-Marguerite Hospital, Marseille, Franc...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::A search for an allergic cause in asthma is fundamental to the diagnosis. Typically it is based on: A clinical history. Specific cutaneous and inhaled provocation tests which can produce a possible reaction (early and delayed) which are of great pathophysiological and therapeutic interest. In vitro tests (which enable...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Recent progress in the physiology of the upper airways has led to significant advances in evaluating the dynamics of upper airway occlusion during sleep. Measuring the collapsibility of the upper airways and localizing the site of obstruction should theoretically lead to efficacious non-mechanical treatment and enable...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:2000-06-01 00:00:00
abstract::Nowadays the diagnosis of pulmonary embolism (PE) is based on a "diagnostic strategy" rather than a single test. The first step, after identifying patients with suspicion of PE, is to establish the pre-test clinical probability. Several scores are available to make a standardised and reproducible assessment of the cli...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2010.10.039
更新日期:2011-06-01 00:00:00
abstract::Two strategies are possible for targeting distal airways in asthma. The first one is systemic, with the delivery of medications either orally or intravenously. Montelukast is the only oral drug that has demonstrated its efficacy on distal airways by reducing lung hyperinflation. The second possible strategy is to deli...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/s0761-8425(09)73681-2
更新日期:2009-10-01 00:00:00
abstract:INTRODUCTION:Exercise testing is useful in the respiratory evaluation of patients with cystic fibrosis. The shuttle walk test (SWT) is a progressive, externally paced, exercise test requiring the subject to walk/run back and forth between two fixed points. The aim is to assess the reproductibility of the SWT in paediat...
journal_title:Revue des maladies respiratoires
pub_type: 临床试验,杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract:INTRODUCTION:The correct use of medication and the ability to assess the severity of the disease and to react appropriately in the case of exacerbation are essential objectives in the management of asthma patients. This study, conducted in a school of asthma in Seine-Saint-Denis, aims to measure the influence of socio-...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2014.02.008
更新日期:2015-03-01 00:00:00
abstract::An analysis of the way the pharyngeal musculature modulates the caliber of the pharynx is important to better understand and treat obstructive sleep apnea syndromes. The caliber of the pharynx at the soft palate depends on the action of the tensor veli, the palatoglossus, the palatopharyngeus and the uvula muscles. At...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1999-02-01 00:00:00
abstract:INTRODUCTION:This questionnaire-based epidemiological study was aimed at identifying possible sleep disturbance in a sample of active French males. METHODS:Eight hundred and fifty male subjects, aged 22 to 66 years, completed a structured sleep questionnaire supplemented by information about their life habits and medi...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2010.07.003
更新日期:2010-09-01 00:00:00
abstract:INTRODUCTION:Mycobacterium malmoense (MM) is an atypical mycobacterium responsible for opportunistic infection. The clinical and radiological picture is non-specific. The infection develops most frequently in a dystrophic lung. CASE REPORT:A patient of 52 years was admitted with an extensive multifocal pneumonia which...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(08)74984-2
更新日期:2008-11-01 00:00:00
abstract::The article has as purpose to propose a systematic approach for the reading of meta-analysis. Using a particular example, a literature search is proposed to identify the two types of meta-analyses: those based on individual data of the patients and those performed in systematic reviews of the literature. The proposed ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract::A case of acute interstitial pneumonia with hypoxaemia is described; this occurred after the cessation of cortico steroids in a patient suffering from myeloma treated with melphalan. The absence of any microbes and the lymphocytosis in the bronchoalveolar lavage and the rapid and favourable improvement on cortico ster...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-01 00:00:00
abstract:INTRODUCTION:Respiratory muscles strength and endurance influence athletic performance. Besides conventional spirometry, sniff test, inspiratory and expiratory maximal pressures can directly assess respiratory muscle strength. Respiratory muscles can be train through a device offering inspiratory and expiratory resista...
journal_title:Revue des maladies respiratoires
pub_type: 临床试验,杂志文章
doi:10.1016/j.rmr.2011.01.008
更新日期:2011-05-01 00:00:00
abstract:INTRODUCTION:Spontaneous pneumomediastinum is a little known cause of chest pain in young adults. The prognosis is invariably good. CASE REPORT:The authors report two cases of spontaneous pneumomediastinum with different aetiologies developing in young adults. The first occurred during strenuous sport and the second d...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2006-02-01 00:00:00
abstract::Static lung hyperinflation is defined as the elevation of end- expiratory lung volume above its predicted value, with no increase in end-expiratory alveolar pressure, which remains equal to atmospheric pressure. Dynamic hyperinflation is the transient increase of this volume above the relaxation volume. In patients wi...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/s0761-8425(08)75094-0
更新日期:2008-12-01 00:00:00
abstract::The human intestinal microbiota is composed of approximately 100,000 billion microorganisms with the average total number of different commensal bacterial species estimated at over 500 per individual. The human intestinal microbiota can be considered as an organ within another, which co-evolved with its host to achiev...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2016.11.003
更新日期:2017-12-01 00:00:00
abstract:INTRODUCTION:Intensivists are increasingly implementing end-of-life decisions in patients who remain dependent on life sustaining therapies without hope for recovery. STATE OF THE ART:Descriptive studies have provided epidemiological data on ICU end-of-life care, identifying areas for improvement. Qualitative studies ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:2006-09-01 00:00:00
abstract::Recognition of the criteria of severity and the early admission to a referral center play a critical role in the prognosis of severe haemoptysis. The therapeutic management should be undertaken urgently by providing general supportive care, i.e., optimization of oxygenation and haemodynamic stabilization to prevent re...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2010.10.006
更新日期:2010-12-01 00:00:00
abstract::Spiral scanning (BSV) is a newly acquired scanning technique for all or part of the thoracic volume in a single breath-hold. It offers many advantages when compared to conventional CT scanning. The study of the lungs with a single breath-hold avoids the inconvenience of an anatomical discontinuity while acquiring the ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:This article describes the French data which contributed to the international "Continuing to Confront COPD" (C2C) survey conducted in 2013 across 12 countries. Its objective was to describe the characteristics, symptoms and impact of COPD on health status, daily activities and working life in adults identi...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2016.05.001
更新日期:2017-03-01 00:00:00
abstract::This article reports an exchange of unbiased arguments between Mr Guy Postiaux speaking in favour of respiratory physiotherapy in acute viral bronchiolitis in the newborn and Prof. Jean-Christoph Dubus arguing against. A review of the literature suggests that traditional methods of physiotherapy should be abandoned be...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2017.08.003
更新日期:2018-04-01 00:00:00
abstract::We report the observation of a 78 year old patient who had a plexiform ameloblastoma since the age of 38. A systematic pulmonary radiographic examination revealed multiple dense nodules like "cannon ball secondaries". However the histology of these pulmonary nodules, obtained by open lung biopsy, was identical with th...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:INTRODUCTION:The aim of the article is to present a summary of current knowledge on tobacco smoking in France available through representative population surveys. STATE OF ART:Smoking is very common in France as more than a quarter (28.7%) of 15-75years old individuals reported daily smoking in 2016. The rate is also ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2018.01.008
更新日期:2018-06-01 00:00:00
abstract::We reviewed the records of 15 Human Immunodeficiency Virus (HIV) infected patients with pulmonary cryptococcosis (PC). PC was the first AIDS-defining manifestation in nine patients. HIV infection was identified simultaneously with the onset of PC in 4 patients. The CD4+ lymphocyte count was low in all cases (median, 2...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract:INTRODUCTION:A chylothorax can occur following any intrathoracic procedure. It is generally straightforward to make the diagnosis but optimal management can be problematic. METHODS:Between 1995 and 2002, three women and one man aged from 13 to 58 years were treated for chylothorax after thoracic surgery. Their initial...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(06)71479-6
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVES:To estimate the prevalence of treated chronic obstructive pulmonary disease (COPD) and its associated costs by stage of severity. METHODS:The study was conducted on the 2011 data of the french general beneficiary sample database (EGB). EGB is a 1/97th sample of the whole population of the beneficiaries of t...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2014.10.731
更新日期:2015-09-01 00:00:00
abstract:INTRODUCTION:Six minutes walking test (6MWT) is regularly used in pulmonology. To minimize the risk of cross-infection, some patients must wear surgical mask at rest and sometimes during exercise. AIM OF THE STUDY:To evaluate the effect of wearing a surgical mask during 6MWT in healthy subjects. MATERIAL AND METHOD:I...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.rmr.2017.01.010
更新日期:2018-03-01 00:00:00