Abstract:
:Of 167 patients with Hodgkin's disease seen in a single centre between December 1972 and December 1982, only one has developed a myelodysplastic state. Between 1972 and 1977, therapy consisted of radiotherapy alone for early-stage disease, combined-modality treatment for intermediate-stage disease and chemotherapy alone using mustine, vinblastine, prednisone and procarbazine (MVPP) for advanced disease. Seventy-one per cent of these patients are disease-free at 5-10 years. From 1978, chlorambucil was substituted for mustine in the chemotherapy schedule (CLVPP). Combined-modality therapy has been used more frequently for patients with Stage III disease since 1978. Complete remission rates for patients treated with MVPP and CLVPP alone were 79% and 78%, respectively. Eight patients (5%) have been designated as a clinical subgroup of 'chronic relapsing' Hodgkin's disease. This chronic relapsing subgroup received substantially more chemotherapy than the remainder and one of these patients has developed a myelodysplastic state. Patients within the chronic relapsing group can be recognised and it is possible to obtain and maintain substantial remissions with fewer courses of chemotherapy than is currently the norm.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Proctor SJ,Evans RGdoi
10.1016/s0009-9260(85)80186-0subject
Has Abstractpub_date
1985-09-01 00:00:00pages
461-4issue
5eissn
0009-9260issn
1365-229Xpii
S0009-9260(85)80186-0journal_volume
36pub_type
杂志文章abstract::The absorption of vitamin B12 and of a synthetic bile acid analogue 75SeHCAT was measured simultaneously in 26 patients presenting with persistent diarrhoea following pelvic irradiation for treatment of carcinoma of the cervix. Four groups were identified, namely patients with isolated bile acid malabsorption, patient...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80059-3
更新日期:1985-05-01 00:00:00
abstract::Visceral situs, as evidenced by the position of the stomach and liver on the plain film, does not predict atrial situs as accurately as does bronchial situs. In particular situs ambiguus of the atria is not reliably indicated by visceral situs, and its subdivision into either right and left isomerism, where both atria...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(79)80056-2
更新日期:1979-01-01 00:00:00
abstract::The results of 100 attempts at endoscopic retrograde cholangio-pancreatography (ERCP) performed in patients with jaundice have been reviewed. The examination provided a diagnosis in 75% of cases. The reason for failure to cannulate the correct duct was obstruction at the lower end of the common bile duct in 15 patient...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(78)80236-0
更新日期:1978-03-01 00:00:00
abstract::The results are presented of a five-year prospective trial of 411 patients with breast carcinoma treated by mastectomy and post-operative radiotherapy. Twice or thrice weekly dose-fractionation techniques were used, i.e. 12 fractions in 28 days and six fractions in 18 days. The results show that, in terms of survival ...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(75)80064-x
更新日期:1975-07-01 00:00:00
abstract::Pulmonary cysts, cavities, and honeycombing are seen in a number of systemic disorders. The purpose of this review is to discuss the findings on thin-section computed tomography (CT) in both congenital and acquired multisystem conditions that give rise to multiple cystic spaces in the lungs. Conditions discussed inclu...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2008.09.015
更新日期:2009-04-01 00:00:00
abstract:AIM:To establish a "one-stop" dysphagia service in which a consultation, barium swallow and endoscopy can all be performed in the same hospital visit. MATERIALS AND METHODS:In order to allow both barium swallow examination and endoscopy to be performed on the same day, a novel technique for clearing barium from the up...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2000.0637
更新日期:2001-01-01 00:00:00
abstract::Two patients with benign chondrolipomatous tumours of the breast were subjected to mammography. In one case this was as part of the investigation of a breast lump detected clinically, while in the other the lesion was detected during routine follow-up of a woman with long-standing cystic hyperplasia. The mammographic ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(88)80560-9
更新日期:1988-05-01 00:00:00
abstract::During the last 4 years we have treated four patients with extensive mediastinal non-Hodgkin's lymphoma (NHL). None had extrathoracic disease and they were clinically stage I-II. All received intensive combination chemotherapy and radiotherapy resulting in good response. Nevertheless, when treatment was completed, com...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(89)80183-7
更新日期:1989-05-01 00:00:00
abstract::Six cases with bacteriologically and/or histologically proven breast tuberculosis were analysed out of 1152 consecutive mammograms performed. The objective was to identify some factors that may facilitate pre-operative mammographic and ultrasonographic diagnosis of breast tuberculosis. Nipple retraction and coarse str...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(96)80115-2
更新日期:1996-05-01 00:00:00
abstract::This study reviews prospectively a series of 29 patients who were examined by magnetic resonance imaging (MRI) and discography for degenerative disc disease. All had persistent low-back pain and non-diagnostic initial investigations, including plain films, myelography and/or computed tomography (CT). The imaging chara...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)82113-0
更新日期:1990-10-01 00:00:00
abstract:AIM:To explore the value of CT spectral imaging in the differential diagnosis of necrotic hepatocellular carcinoma (nHCC) and hepatic abscess (HA) during the arterial phase (AP) and portal venous phase (PP). MATERIALS AND METHODS:Sixty patients with 36 nHCCs and 24 HAs underwent spectral CT during AP and PP. Iodine or...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2014.08.018
更新日期:2014-12-01 00:00:00
abstract:AIM:To assess the effect of the presence and locality of symptomatic lower-limb deep vein thrombosis (DVT) on mortality and morbidity following contrast venography (CV), the reference standard for diagnosing below-knee DVT, with a view to determining the prevalence of recurrent episodes of DVT and post-thrombotic syndr...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.12.014
更新日期:2016-04-01 00:00:00
abstract::Colour Doppler scans were carried out on 80 patients with breast carcinoma. Both the tumour and the lower axilla were scanned in all 80 patients. Seventy-five patients subsequently underwent axillary lymph node dissection and histological examination. The sensitivity of colour Doppler scanning for axillary node involv...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81774-x
更新日期:1994-03-01 00:00:00
abstract::Patients with leukaemia, on anticoagulant therapy, or with disseminated intravascular coagulation may develop occult pulmonary haemorrhage; it will mimic pulmonary oedema, pulmonary hemosiderosis or opportunistic infections. It can be diagnosed by bronchopulmonary lavage. The radiographic changes are described and the...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(78)80217-7
更新日期:1978-03-01 00:00:00
abstract::Experience with ultrasound compound 'B' scanning in 18 cases of hydatidiform mole is presented. The scan appearances are analysed with respect to the presence or absence of transonic areas, and to the uniformity of echogenicity elsewhere in the uterus. The differential diagnosis is discussed. The commonest appearance ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(77)80045-7
更新日期:1977-11-01 00:00:00
abstract::In 20 years we have seen only 78 cases of primary vaginal cancer. 61 patients had squamous carcinoma, three had adenocarcinoma, 10 had clear-cell carcinoma, four of which may have been metastatic from carcinoma of the kidney, and four had malignant melanoma. The actuarial 5-year survival of patients with squamous canc...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(86)80160-x
更新日期:1986-01-01 00:00:00
abstract:AIM:To compare the diagnostic quality of time-of-flight magnetic resonance angiography (TOF-MRA) and metal-artefact-reduction (MAR) flat-panel-detector computed tomography angiography (FPCTA) and to determine the imaging technique best suited for evaluation endovascular and surgically treated aneurysms. METHODS:The im...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.07.011
更新日期:2018-02-01 00:00:00
abstract::Endovascular mechanical thrombectomy (MT) is reserved for acute ischaemic stroke secondary to large vessel occlusion. The various MT techniques employed in the treatment of hyperacute strokes are constantly evolving with new devices and improvisation of existing technology (Wahlgren, et al 2016). In this review, we de...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.10.022
更新日期:2018-05-01 00:00:00
abstract:AIM:To evaluate the risk of cancer of an enhancing focus identified at breast magnetic resonance imaging (MRI) by determining the positive predictive value (PPV) associated with specific characteristics of an enhancing focus. MATERIALS AND METHODS:Retrospective, institutional review board-approved review of the databa...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2014.02.007
更新日期:2014-07-01 00:00:00
abstract:AIM:To assess the accuracy of low-dose contrast-enhanced time-resolved 3T magnetic resonance angiography (MRA) for the morphological and functional assessment of vascular malformations (VM), and to evaluate its diagnostic potential for the depiction of treatment-induced changes. MATERIALS AND METHODS:Twenty-five patie...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2011.08.003
更新日期:2011-12-01 00:00:00
abstract:AIM:To differentiate uric acid from non-uric acid renal stones based on their spectral attenuation values. MATERIALS AND METHODS:The present study was approved by the institutional review board and the need for informed consent was waived. Thirty-three consecutive patients (21 men, 12 women; mean age 55 years) with sy...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.01.018
更新日期:2017-06-01 00:00:00
abstract::The absence of rectal gas is said to be a sign of Hirschsprung's disease, especially when there is also gaseous distension of the bowel proximally. This paper reviews 136 neonates who had plain abdominal radiographs. There were 83 patients with multiple examinations, of which 52 (63%) showed variability in the presenc...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80253-3
更新日期:1991-04-01 00:00:00
abstract::Hereditary ovarian tumour syndromes are a diverse group of hereditary syndromes characterised by the development of specific histotypes of ovarian neoplasms. While BRCA syndromes are exclusively associated with high-grade serous carcinomas, patients with Lynch syndrome show a preponderance of endometrioid subtype of o...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2020.11.116
更新日期:2020-12-19 00:00:00
abstract::Extracranial carotid artery aneurysms secondary to accidental injury are rare. We have seen eight lesions of this type in the last 10 years. The aneurysm was produced by blunt trauma in four patients, penetrating shrapnel injury in two, stabbing and electrical injury in one each. The left side was involved in seven pa...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80471-4
更新日期:1991-03-01 00:00:00
abstract::Fibrosing alveolitis was studied by high definition, narrow section computed tomography (CT) in 50 patients, 30 of whom were suffering from systemic sclerosis and 20 from cryptogenic fibrosing alveolitis (CFA). Apart from changes in the mid and lower zones, abnormalities were also observed anteriorly in the upper lobe...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(88)80056-4
更新日期:1988-11-01 00:00:00
abstract::The heart and mediastinal structures can be overlooked at CT pulmonary angiogram (CTPA). This pictorial review will demonstrate the features of cardiac disease that may be evident on a CTPA. CTPA allows assessment of not only the pulmonary arteries for embolism, but also of the bronchi, lung parenchyma, mediastinum an...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2004.07.005
更新日期:2005-01-01 00:00:00
abstract:AIM:To assess multiparametric magnetic resonance imaging (mp-MRI) in predicting prostate biopsy results. MATERIALS AND METHODS:Patients who underwent mp-MRI prior to prostate biopsy were prospectively included. The prostate was subdivided into 14 sectors and mp-MRI findings assessed using a five-level subjective suspi...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2013.10.018
更新日期:2014-03-01 00:00:00
abstract::The intravascular contrast media in current use are solutions of salts of tri-iodinated substituted benzoic acids. Haemodynamic changes following injection of these contrast media are due mainly to their high osmolar concentration which is five to eight times physiological levels. In this study we compare the effect i...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(80)80001-8
更新日期:1980-11-01 00:00:00
abstract::Digital imaging has shown rapid advances in recent years. Various different digital mammography systems are now available for clinical use. Digital mammography does have clear advantages over traditional screen film mammography, but this is yet to convincingly translate into improved cancer detection rates. This revie...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2003.08.011
更新日期:2004-01-01 00:00:00
abstract::The accuracy of computed tomography (CT) in the assessment of nodal metastases was correlated retrospectively with the pathological examination in 28 patients with known head and neck squamous cell carcinoma, who underwent neck dissections. Three patients had bilateral neck dissections resulting in a total of 31 disse...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80500-8
更新日期:1991-08-01 00:00:00