Abstract:
:The results are presented of a five-year prospective trial of 411 patients with breast carcinoma treated by mastectomy and post-operative radiotherapy. Twice or thrice weekly dose-fractionation techniques were used, i.e. 12 fractions in 28 days and six fractions in 18 days. The results show that, in terms of survival and control of local disease, the two techniques are very similar. The early and late radiation effects on the normal tissues up to five years are similar and acceptable. Dose levels thought to be biologically equivalent on the basis of experience at St Thomas's Hosiptal were selected. It is stressed that there is a narrower margin of normal tissue tolerance when six fractions over 18 days are used, that it is essential to treat all fields on each treatment occasion and that the total maximum tissue dose of 3600 R is not exceeded. Attention is drawn to the fact that the dose for six fractions, derived from the NSD formula which would be predicted to be equivalent to the 12-fraction dose is, in fact, over 10% higher than the dose used here and likely to produce unacceptable late radiation changes.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Bates TDdoi
10.1016/s0009-9260(75)80064-xsubject
Has Abstractpub_date
1975-07-01 00:00:00pages
297-304issue
3eissn
0009-9260issn
1365-229Xjournal_volume
26pub_type
临床试验,杂志文章,随机对照试验abstract::The heart and mediastinal structures can be overlooked at CT pulmonary angiogram (CTPA). This pictorial review will demonstrate the features of cardiac disease that may be evident on a CTPA. CTPA allows assessment of not only the pulmonary arteries for embolism, but also of the bronchi, lung parenchyma, mediastinum an...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2004.07.005
更新日期:2005-01-01 00:00:00
abstract::Two patients successfully treated for Hodgkin's disease with radiotherapy alone subsequently developed a non-Hodgkin's lymphoma. One patient presented with a pleural effusion and a paraprotein band, the second with recurrent lymphadenopathy. Their case histories are compared with the five others previously reported. F...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(86)80060-5
更新日期:1986-09-01 00:00:00
abstract::Appendicitis can be a difficult clinical diagnosis to make. A negative appendicectomy rate of 20% has traditionally been accepted as the consequences of appendiceal perforation can be grave. Cross-sectional imaging is increasingly being employed in the investigation of adults with suspected appendicitis. This review w...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2008.06.015
更新日期:2009-02-01 00:00:00
abstract::Computed tomographic (CT) findings in two cases of hepatic oil embolism following lymphangiography are described. Both patients had lymphatic obstruction and opacification of the liver due to collateral flow of lymphangiographic contrast. Computed tomography of the liver showed a distinctive branching pattern due to t...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(89)80189-8
更新日期:1989-05-01 00:00:00
abstract::The pre-operative images of three patients with biopsy proven esthesioneuroblastoma are presented. The role of computed tomography (CT) and magnetic resonance imaging (MRI) in the pre-operative determination of tumour extent is discussed. ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)83295-7
更新日期:1995-09-01 00:00:00
abstract::The lymphatic system of the abdomen comprises of the cisterna chyli, its major and minor lymphatic tributaries, and lymph nodes. Disorders of the lymphatic system of the abdomen are rarely encountered and consist of primary and secondary types. Abdominal lymphangiomas constitute the majority and have characteristic im...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2016.06.116
更新日期:2016-10-01 00:00:00
abstract:AIM:To estimate the sensitivity and specificity of computed tomography (CT) for the diagnosis of deep vein thrombosis (DVT) in patients with suspected DVT and pulmonary embolus (PE). MATERIALS AND METHODS:A search of the medical literature and citation lists was undertaken, and selected studies comparing CT to a refer...
journal_title:Clinical radiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.crad.2007.09.010
更新日期:2008-03-01 00:00:00
abstract::A prospective study was performed in 138 consecutive patients referred for small-bowel examination to evaluate the use of the pneumocolon when there was poor demonstration of the terminal ileum. One hundred and twenty-two patients were examined by enteroclysis (small-bowel enema) and 16 by small-bowel meal. Pneumocolo...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80253-1
更新日期:1985-11-01 00:00:00
abstract:AIM:To compare the diagnostic utility of pelvic ultrasound (US) and magnetic resonance imaging (MRI) on the clinical decision to proceed with uterine artery embolization (UAE). MATERIALS AND METHODS:Over 2 years, 180 consecutive women (mean age 43) sought consultation for UAE, 116 underwent pelvic US and MRI before po...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2010.08.005
更新日期:2011-01-01 00:00:00
abstract:AIM:To assess the accuracy of low-dose contrast-enhanced time-resolved 3T magnetic resonance angiography (MRA) for the morphological and functional assessment of vascular malformations (VM), and to evaluate its diagnostic potential for the depiction of treatment-induced changes. MATERIALS AND METHODS:Twenty-five patie...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2011.08.003
更新日期:2011-12-01 00:00:00
abstract::In this report, we illustrate the imaging findings of diseases in the subperitoneal space of the broad ligament and sigmoid mesocolon and discuss the pathways of subperitoneal spread of disease. The subperitoneal space of the broad ligament and sigmoid mesocolon is continuous with that of the parietal peritoneum overl...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/s0009-9260(98)80213-4
更新日期:1998-12-01 00:00:00
abstract:AIM:To examine whether Positron Emission Tomography Response Criteria in Solid Tumours (PERCIST) is useful to predict tumour response and prognosis of patients with oesophageal cancer who received neoadjuvant chemoradiotherapy (NACRT) followed by surgery. MATERIALS AND METHODS:This multicentre retrospective study incl...
journal_title:Clinical radiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.crad.2019.09.132
更新日期:2020-01-01 00:00:00
abstract::We reviewed our experience of the therapeutic role of radiology in Budd-Chiari syndrome. Patients with stenosis and/or occlusion of the main hepatic veins and/or inferior vena cava (IVC) are suitable for radiological intervention (35% in our series). Eighteen patients (mean age 37.4 years) have undergone radiological ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(96)80005-5
更新日期:1996-11-01 00:00:00
abstract::Forty patients, mainly post-operative, were examined for suspected leakage from the oesophagus and/or stomach using iopamidol. Oesophageal leaks were demonstrated in seven patients, tracheo-oesophageal fistulae in two and an unsuspected gastro-jejunostomy intusussception in one. Only two cases were regarded as technic...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(87)80022-3
更新日期:1987-03-01 00:00:00
abstract:AIM:To assess the effect of the presence and locality of symptomatic lower-limb deep vein thrombosis (DVT) on mortality and morbidity following contrast venography (CV), the reference standard for diagnosing below-knee DVT, with a view to determining the prevalence of recurrent episodes of DVT and post-thrombotic syndr...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.12.014
更新日期:2016-04-01 00:00:00
abstract:AIM:To validate the role of nuclear medicine (NM) imaging in hip periprosthetic joint infection (PJI) of hip arthroplasties. MATERIALS AND METHODS:This was a retrospective study of 235 consecutive patients referred to NM for investigation of a symptomatic hip prosthesis. Imaging comprised Tc-99m bone scintigraphy, In-...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.10.026
更新日期:2016-03-01 00:00:00
abstract:AIM:The purpose of our study was to describe radiological manifestations of tuberculosis in patients with myelodysplastic syndromes. MATERIALS AND METHODS:Chest radiographs and CTs of 12 patients with tuberculosis among 195 consecutive patients with myelodysplastic syndrome, proved by bone marrow biopsy, were reviewed...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2001.0742
更新日期:2002-05-01 00:00:00
abstract::The trigeminal nerve is the largest cranial nerve and has both sensory and motor components. Due to its extensive distribution in the head and neck, the nerve or its branches may be involved by a myriad of disease entities. Additionally, the nerve may act as a route of spread in various inflammatory and neoplastic dis...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2012.05.019
更新日期:2013-02-01 00:00:00
abstract::Prostate cancer is the second most prevalent cancer in men worldwide and its incidence is expected to double by 2030. Multi-parametric magnetic resonance imaging (MRI) incorporating anatomical and functional imaging has now been validated as a means of detecting and characterising prostate tumours and can aid in risk ...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2015.06.093
更新日期:2015-11-01 00:00:00
abstract::This is the fifth in the series of short reviews of internet-based radiological learning resources and will focus on gastrointestinal (GI) and hepatobiliary radiology. Below are details of a few of the higher quality resources currently available. Most of the sites cater for medical students and trainee or non-special...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2006.01.005
更新日期:2006-05-01 00:00:00
abstract::In a prospective study, A mode ultrasound scanning contributed to the diagnosis and management of 24 of 50 consecutive patients with pleural disease. In 30% of patients it was superior to radiology in clarifying the solid or fluid nature of a pleural opacity, and in 42% of patients it allowed selection of the most app...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(81)80042-6
更新日期:1981-05-01 00:00:00
abstract::Ultrasound is a routine investigation for the assessment of scrotal masses. Many of the detected lesions involve the paratesticular structures. The most common paratesticular masses in clinical practice are epididymal cysts and spermatoceles, but there are a large number of other pathologies that can be encountered an...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2007.09.004
更新日期:2008-08-01 00:00:00
abstract::Nine patients with bullous emphysema for which surgery was being considered have been investigated with computed tomography (CT). In six out of nine patients (67%) CT showed more extensive disease or bilateral disease where only unilateral was suspected from postero-anterior and lateral chest radiographs. Only one pat...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(84)80232-9
更新日期:1984-01-01 00:00:00
abstract::Three-dimensional (3D) computed tomography (CT) reformations were obtained in 15 patients presenting with facial injuries of differing severity. The 3D images were compared with standard radiographs and high resolution CT, including multiplanar reformations, and assessed under the headings of fracture detection, exten...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(87)80144-7
更新日期:1987-09-01 00:00:00
abstract::Thw radiological appearances found in the pelvis and hip joints in 79 patients with cerebral palsy, aged 5--16 years, have been studied. These findings have been recorded and correlated with the clinical severity and distribution of the disease. Subluxation of the hip joints was found in 14% and dislocation in a furth...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(77)80099-8
更新日期:1977-03-01 00:00:00
abstract::Sixty-four patients (37 stage I and 27 stage II) with low grade non-Hodgkin's lymphoma were treated by surgical excision alone (two patients) or with radiotherapy (53 patients), chemotherapy (five patients) or both (four patients). Actuarial survival was 80.7% at 5 years and 77.9% at 10 years. Actuarial recurrence-fre...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(88)80537-3
更新日期:1988-05-01 00:00:00
abstract:AIM:To provide a diagnostic approach to pulmonary nodules in patients with chondrosarcoma. MATERIALS AND METHODS:A search of the oncology database at a specialist orthopaedic oncology referral centre was performed to identify all patients who were treated surgically for chondrosarcoma between January 2007 and December...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2019.11.017
更新日期:2020-05-01 00:00:00
abstract:AIMS:To describe the optimum conditions for successful free-hand ultrasound guided intervention using an in-vitro experiment. MATERIALS AND METHODS:Optimal free-hand biopsy conditions were determined using targets buried in a purpose-built interventional phantom. The needle/probe distance and probe/phantom surface ang...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2000.0579
更新日期:2001-06-01 00:00:00
abstract::Skeletal radiological surveys in 161 renal transplant recipients identified 36 patients with 115 lesions of osteonecrosis. A further two patients with osteonecrosis found at autopsy had had no radiographic abnormality. The total incidence of osteonecrosis was, therefore, 38 (24%) out of 161. The lesions were frequentl...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80012-x
更新日期:1985-01-01 00:00:00
abstract::Since Lord Woolf declared in 2001 that the courts have been excessively deferential to the medical profession, there has been an incremental series of changes to the law concerning medical negligence. The most substantial changes concern consent, but significant change has also appeared regarding the concept of causat...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2020.05.005
更新日期:2020-10-01 00:00:00