An evaluation of the role of nuclear medicine imaging in the diagnosis of periprosthetic infections of the hip.

Abstract:

AIM:To validate the role of nuclear medicine (NM) imaging in hip periprosthetic joint infection (PJI) of hip arthroplasties. MATERIALS AND METHODS:This was a retrospective study of 235 consecutive patients referred to NM for investigation of a symptomatic hip prosthesis. Imaging comprised Tc-99m bone scintigraphy, In-111 white cell scintigraphy, and bone marrow scintigraphy if required. Imaging findings were compared with intraoperative microbiology and histology, clinical findings and follow up for ≥ 24 months. RESULTS:There were 14 exclusions. Of the 221 remaining patients, there were 16 true positives, one false positive, 200 true negatives, and four false negatives. The algorithm used at this centre demonstrated an accuracy of 97.7% with high specificity of 99.5% and sensitivity of 80%. CONCLUSION:When modern NM techniques and accurate reporting criteria are used, scintigraphy is an effective tool for diagnosing PJI of the hip. NM is only given a marginal role in the recent American Association of Orthopedic Surgeons guidelines, and the orthopaedic community should reconsider their evaluation of this technique.

journal_name

Clin Radiol

journal_title

Clinical radiology

authors

Trevail C,Ravindranath-Reddy P,Sulkin T,Bartlett G

doi

10.1016/j.crad.2015.10.026

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

211-9

issue

3

eissn

0009-9260

issn

1365-229X

pii

S0009-9260(15)00427-4

journal_volume

71

pub_type

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