Abstract:
AIM:To provide a diagnostic approach to pulmonary nodules in patients with chondrosarcoma. MATERIALS AND METHODS:A search of the oncology database at a specialist orthopaedic oncology referral centre was performed to identify all patients who were treated surgically for chondrosarcoma between January 2007 and December 2018. Reports from the computed tomography (CT) examinations of the thorax of these patients were reviewed. In patients who had pulmonary nodules/metastases identified on CT, data on the primary chondrosarcoma and pulmonary nodule characteristics were collected. RESULTS:Twenty point two percent of patients had a pulmonary nodule identified on either initial or follow-up staging CT of the thorax, of which 8.1% were pulmonary metastases. Patients with grade 3 and dedifferentiated chondrosarcoma were more likely to have pulmonary metastases than patients with grade 1/2 chondrosarcoma. The time interval to developing metastases was shorter in patients with grade 2/3 and dedifferentiated chondrosarcoma versus patients with grade 1 chondrosarcoma. A low proportion of patients with grade 1 chondrosarcoma developed metastases (12.5%), all of which were identified at the time of a local recurrence. Nodules ≥10mm, nodules with lobulate margins, nodules containing irregular or subtle calcification, and nodules seen bilaterally or both centrally and peripherally were more likely to represent pulmonary metastases than benign nodules. CONCLUSION:The diagnostic significance of pulmonary nodules (i.e., whether they represent pulmonary metastases or not) can be predicted by taking into account a number of factors, in particular, the histological grade of the patient's chondrosarcoma, the size and margins of the nodules, and the presence of subtle/irregular calcification.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
McLoughlin E,Davies AM,Iqbal A,James SL,Botchu Rdoi
10.1016/j.crad.2019.11.017subject
Has Abstractpub_date
2020-05-01 00:00:00pages
395.e7-395.e16issue
5eissn
0009-9260issn
1365-229Xpii
S0009-9260(19)30676-2journal_volume
75pub_type
杂志文章abstract::Gastrointestinal bleeding following abdominal aortic bypass surgery is not uncommon, as approximately 20% of patients with abdominal aortic aneurysms have peptic ulcer disease. We have recently seen three patients who presented with gastrointestinal bleeding secondary to the complications of their surgery. The cause o...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(76)80160-2
更新日期:1976-04-01 00:00:00
abstract::We present nine cases of this relatively unreported condition affecting the patellar ligament in athletes. A comparison between ultrasound and computed tomography of this lesion, shows that whilst neither modality gives false positives, ultrasound is capable of greater distinction between the histological abnormalitie...
journal_title:Clinical radiology
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abstract::Pelvic phleboliths were demonstrated in 1000 subjects aged 16--79 years (mean 42.1, s.d. 12.7). They occurred in 44.2% of the subjects, in 37.3% of the males and 50.1% of the females. Among subjects between the ages of 35 and 54, phleboliths occurred more frequently in the females than in the males. In addition the ol...
journal_title:Clinical radiology
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doi:10.1016/s0009-9260(80)80095-x
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
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abstract:AIM:To determine the willingness of women with extremely dense breasts to undergo breast cancer screening with magnetic resonance imaging (MRI) in a research setting, and to examine reasons for women to participate or not. MATERIALS AND METHODS:Between 2011 and 2015, 8,061 women (50-75 years) were invited for suppleme...
journal_title:Clinical radiology
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Clinical radiology
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journal_title:Clinical radiology
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doi:10.1016/j.crad.2009.04.008
更新日期:2009-08-01 00:00:00
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journal_title:Clinical radiology
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pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81626-5
更新日期:1990-07-01 00:00:00
abstract::Five patients with deep pelvic abscesses underwent computed tomography (CT)-guided catheter drainage using a transrectal approach. The use of an outer removable plastic sheath over the catheter to facilitate positioning and prevent inadvertent damage to the mucosal wall is described. This new approach using CT guidanc...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80007-8
更新日期:1992-04-01 00:00:00
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doi:10.1016/j.crad.2009.03.013
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pub_type: 临床试验,杂志文章
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更新日期:2013-12-01 00:00:00
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doi:10.1016/j.crad.2015.07.009
更新日期:2016-01-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81593-4
更新日期:1991-02-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.crad.2011.03.009
更新日期:2011-08-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1016/j.crad.2005.12.005
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
doi:10.1016/j.crad.2005.08.017
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81142-0
更新日期:1993-04-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
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journal_title:Clinical radiology
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81973-7
更新日期:1994-11-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
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更新日期:2010-08-01 00:00:00