Improved control of primary vaginal tumours by combined external-beam and interstitial radiotherapy.

Abstract:

:In 20 years we have seen only 78 cases of primary vaginal cancer. 61 patients had squamous carcinoma, three had adenocarcinoma, 10 had clear-cell carcinoma, four of which may have been metastatic from carcinoma of the kidney, and four had malignant melanoma. The actuarial 5-year survival of patients with squamous cancer was: Stage I, 68%; Stage II, 34%; Stage III, 29% and Stage IV, 14%. Patients treated by combined external and intracavitary or interstitial radiotherapy had increased local control and superior survival to those treated by interstitial methods alone. The improved tumour control offered by combination treatment may be due to the elimination of small tumour deposits in lymph nodes within the treated volume and the sterilisation of carcinoma in situ in the vagina some distance from obvious tumour.

journal_name

Clin Radiol

journal_title

Clinical radiology

authors

MacNaught R,Symonds RP,Hole D,Watson ER

doi

10.1016/s0009-9260(86)80160-x

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

29-32

issue

1

eissn

0009-9260

issn

1365-229X

pii

S0009-9260(86)80160-X

journal_volume

37

pub_type

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