Abstract:
:Hereditary ovarian tumour syndromes are a diverse group of hereditary syndromes characterised by the development of specific histotypes of ovarian neoplasms. While BRCA syndromes are exclusively associated with high-grade serous carcinomas, patients with Lynch syndrome show a preponderance of endometrioid subtype of ovarian and endometrial carcinomas. Distinct non-epithelial phenotypes, such as sex cord stromal tumours with annular tubules, Sertoli-Leydig cell tumours, and small cell carcinoma of the hypercalcaemic type occur in patients with Peutz-Jeghers, DICER1, and rhabdoid tumour predisposition syndromes, respectively. Gorlin-Goltz syndrome is characterised by the development of bilateral, multiple ovarian fibromas in 14-24% of patients. Ovarian steroid cell tumours and broad ligament papillary cystadenomas are characteristically found in women with von Hippel-Lindau syndrome. Recent studies have allowed the characterisation of tumour genetics and associated oncological pathways that contribute to tumourigenesis. Implications of the diagnosis of these syndromes on screening, management, and prognosis are discussed.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Shanbhogue KP,Prasad AS,Ucisik-Keser FE,Katabathina VS,Morani ACdoi
10.1016/j.crad.2020.11.116subject
Has Abstractpub_date
2020-12-19 00:00:00eissn
0009-9260issn
1365-229Xpii
S0009-9260(20)30605-Xpub_type
杂志文章abstract::Magnetic resonance imaging (MRI) of the pituitary, hypothalamus and olfactory sulci was performed in 40 patients with idiopathic hypogonadotropic hypogonadism (IHH). Twelve of these patients had an impaired sense of smell (Kallmann's syndrome). Sagittal and coronal imaging revealed no morphological abnormalities in th...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81085-2
更新日期:1993-08-01 00:00:00
abstract:AIM:To examine the functional brain alterations in Parkinson's disease (PD) by measuring blood oxygenation level dependent (BOLD) functional MRI (fMRI) signals at rest while controlling for the structural atrophy. MATERIALS AND METHODS:Twenty-three PD patients and 20 age, gender, and education level matched normal con...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.10.006
更新日期:2016-01-01 00:00:00
abstract::The accuracy of high field, endorectal MRI in the staging of localized prostate cancer has been the focus of many previous reports. We present our findings with a mid-field magnet. Twenty-two patients with clinically localized prostate cancer were prospectively staged with endorectal MRI using a 0.5 T magnet. All pati...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(96)80133-4
更新日期:1996-08-01 00:00:00
abstract::The clinical and radiological presentation of four cases of spontaneous aorto-caval fistula is described. This is an unusual complication of an abdominal aortic aneurysm and presents with abdominal pain, a pulsatile abdominal mass and an abdominal bruit. Our cases illustrate the variable clinical presentation, outline...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(83)80432-2
更新日期:1983-11-01 00:00:00
abstract::In 1979 the Cancer Control Agency of British Columbia changed from radium to remote controlled afterloaded caesium in the treatment of carcinoma of the cervix. In the 3 years prior to the change, 139 patients received radium as part of their treatment and in the 3 years after the change, 158 patients received caesium....
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(89)80214-4
更新日期:1989-05-01 00:00:00
abstract::There is disagreement in the literature about the radiological appearance of the central giant cell granuloma (CGCG) of the jaws. A review of 26 cases of CGCG was undertaken with the aim of resolving this. CGCG were found over a wide age range but most occurred in the 2nd and 3rd decades. Females were more frequently ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(89)80325-3
更新日期:1989-11-01 00:00:00
abstract::Over a 12 month period all patients but one presenting to our hospital with occluded prosthetic grafts were treated by thrombolysis using local pulsed administration of tissue-type plasminogen activator (t-PA). There were 30 interventions in 23 patients but in one patient no thrombolytic was given after aspiration of ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80683-x
更新日期:1992-12-01 00:00:00
abstract:AIM:To determine the diagnostic accuracy of MR imaging in differentiating phaeochromocytoma from other adrenal lesions. MATERIALS AND METHODS:Sixty-seven adrenal masses (65 patients) including 17 phaeochromocytomas were imaged using T2-weighted pulse sequences on 0.6 T and 1.5 T GE MR units. The adrenal lesions were q...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(97)80252-8
更新日期:1997-08-01 00:00:00
abstract::Three patients with pancreatic clonorchiasis were examined with endoscopic retrograde pancreatography. On each of the three cases there was diffuse irregular dilatation of tributaries of the pancreatic duct in the pancreatic tail. The main pancreatic duct and tributaries draining into the body and head portion were no...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80967-5
更新日期:1990-03-01 00:00:00
abstract:AIM:To assess the accuracy and risk factors for complications of computed tomography (CT)-guided percutaneous core needle biopsy (CNB) for small (≤20 mm) pulmonary lesions. MATERIALS AND METHODS:A retrospective study was undertaken comprising 169 patients who underwent CT-guided CNB for small (≤20 mm) pulmonary lesion...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2012.09.008
更新日期:2013-01-01 00:00:00
abstract::Fourteen cases of plasmacytoma arising in the head and neck are described. Good local tumour control was achieved with minimal surgery and moderate doses of radiation. Subsequent myelomatosis did occur but this was unusual and no more frequent with tumours arising in the maxilla and mandible than at extramedullary sit...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(87)80231-3
更新日期:1987-07-01 00:00:00
abstract:AIM:To describe the sequential appearance of healing rib fractures on initial and follow-up radiographs using published guidelines in approximating the age of rib fractures in infants with the aim of establishing a more objective method of dating rib fractures by measuring the thickness of the callous formation. MATER...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2013.03.017
更新日期:2013-08-01 00:00:00
abstract:AIM:To estimate the sensitivity and specificity of computed tomography (CT) for the diagnosis of deep vein thrombosis (DVT) in patients with suspected DVT and pulmonary embolus (PE). MATERIALS AND METHODS:A search of the medical literature and citation lists was undertaken, and selected studies comparing CT to a refer...
journal_title:Clinical radiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.crad.2007.09.010
更新日期:2008-03-01 00:00:00
abstract::Twenty-eight patients with non-Hodgkin's lymphoma of the thyroid were treated between 1954 and 1981. The duration of follow-up ranged from 39 to 176 months. The overall 5 year survival was 51%. Twenty deaths have been recorded of which 12 were attributed to non-Hodgkin's lymphoma. Eight patients relapsed following ini...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(87)80067-3
更新日期:1987-05-01 00:00:00
abstract:AIM:To characterize the computed tomography (CT) and magnetic resonance imaging (MRI) findings of inflammatory myofibroblastic tumours (IMTs) of the maxillary sinus. MATERIALS AND METHODS:The imaging findings of eight patients with IMTs of the maxillary sinus were reviewed retrospectively. Of the eight patients, four ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2012.08.002
更新日期:2012-12-01 00:00:00
abstract:AIM:To investigate the relationship between mammographic breast density (MGD) and background parenchymal enhancement (BPE) at breast MRI and histopathological features of invasive breast cancers. MATERIALS AND METHODS:A total of 178 women with unilateral invasive breast cancer who preoperatively underwent mammography ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.02.017
更新日期:2015-07-01 00:00:00
abstract::Imaging plays a significant role in the detection, characterization and treatment of hepatic infections. Infectious diseases of the liver include pyogenic and amoebic abscesses and parasitic, fungal, viral and granulomatous infections. With increases in worldwide travel, immunosuppression and changing population demog...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2006.03.010
更新日期:2006-09-01 00:00:00
abstract::Hepatic artery thrombosis is a major cause of morbidity and mortality following liver transplantation. We assessed the value of prospective duplex Doppler ultrasound in detecting hepatic artery thrombosis. One hundred consecutive transplants in 90 patients were studied. Duplex Doppler detected all 10 proven cases of h...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81158-4
更新日期:1993-03-01 00:00:00
abstract::In a prospective study 59 consecutive outpatients having double-contrast barium enemas (DCBE) were randomised into four groups. Each group had their enema performed at either a 15, 30, 45 or 60 minute interval following the end of a 1.5 litre cleansing water enema. Review of the films by two radiologists demonstrated ...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(05)81695-2
更新日期:1990-05-01 00:00:00
abstract::In the clinical use of magnetic resonance imaging (MRI) it may be more important to understand some of the technical aspects of the imaging technique, rather than the fundamental physical principles. This review, therefore, sets out to present the essential aspects of the technique, including T1 and T2 relaxation time...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80232-4
更新日期:1985-11-01 00:00:00
abstract::It has previously been suggested that a single dose of magnesium citrate produces adequate cleansing of the bowel for barium enema examination. To determine whether such a regimen has any advantage over the widely used two doses of Picolax, a prospective randomized blinded trial was performed with over 100 patients al...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(05)81821-5
更新日期:1994-06-01 00:00:00
abstract::Intrascrotal masses in the adult are worrisome due to their possible malignancy. Most intratesticular masses are malignant whereas most extratesticular masses are benign. The differential diagnosis of intrascrotal cysts usually includes simple testicular cysts, intratesticular epidermoid and dermoid cysts, tunica albu...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)83198-8
更新日期:1995-08-01 00:00:00
abstract:AIM:To evaluate the role of computed tomography (CT) after herniography in the diagnosis and management of primary and recurrent groin hernias not detectable on clinical examination. MATERIAL AND METHODS:Fifty-one patients underwent CT post-herniography over a 6-year period for suspected primary or recurrent inguinal ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2004.02.013
更新日期:2005-02-01 00:00:00
abstract::The aortic valve may be affected by a wide range of congenital and acquired diseases. Echocardiography is the main non-invasive imaging technique for assessing patho-anatomical alterations of the aortic valve and adjacent structures and in many cases is sufficient to establish a diagnosis and/or guide treatment decisi...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2013.07.014
更新日期:2013-12-01 00:00:00
abstract::Thirty-three patients presenting with spontaneous rupture of hepatocellular carcinomas (HCCs) were referred for emergency transcatheter arterial embolization. Blood was present in the ascitic fluid on abdominal paracentesis in all 33 patients. Seventeen patients underwent emergency computed tomography (CT). HCCs were ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(98)80004-4
更新日期:1998-05-01 00:00:00
abstract::Neuronal migration anomalies form a spectrum of congenital brain malformations with a variety of clinical manifestations. The widespread use of MRI in the investigation of neurological symptoms, and particularly in the imaging of epilepsy, has made the correct recognition and interpretation of these disorders importan...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/s0009-9260(96)80211-x
更新日期:1996-01-01 00:00:00
abstract::There is a pressing clinical need to develop accurate, efficient non-contrast magnetic resonance angiography (NC-MRA) techniques. Our efforts in the field have focused on a novel non-subtractive technique called quiescent-interval slice-selective (QISS) MRA. Compared with other NC-MRA techniques, QISS has the advantag...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.12.003
更新日期:2019-01-01 00:00:00
abstract:AIM:To determine the accuracy and therapeutic success of localisation of impalpable breast lesions by hookwire with additional lesion marking with carbon suspension to mark screen detected abnormalities requiring surgical excision. MATERIALS AND METHODS:Retrospective review of all breast localisation procedures perfor...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2002.0994
更新日期:2002-10-01 00:00:00
abstract::The role of ultrasound for the diagnosis of pyloric stenosis has yet to be definitely established. We have carried out 147 ultrasound examinations of 142 infants (99 male and 43 female) with a history of projectile vomiting or the possibility of a pyloric mass. Measurements of the pyloric canal length, transverse pylo...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81849-5
更新日期:1994-04-01 00:00:00
abstract:AIM:To describe the radiological appearances of immune reconstitution inflammatory syndrome (IRIS) in human immunodeficiency virus (HIV)-infected patients with mycobacterial infections starting highly active anti-retroviral therapy (HAART). MATERIALS AND METHODS:Five consecutive HIV infected patients with IRIS due to ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2003.12.002
更新日期:2004-06-01 00:00:00