Nitrogen inhalation in the human.

abstract：:Experimental allergic neuritis was induced in Lewis rats by inoculation with autoreactive T cell lines sensitized to residue 57-81 of P2 myelin protein. Control rats received cells derived from immunization to complete Freund's adjuvant alone. Endoneurial fluid pressure (EFP) was measured in both sciatic nerves at 0, ...

journal_title：Acta neuropathologica

authors： Powell HC,Myers RR,Mizisin AP,Olee T,Brostoff SW

更新日期：1991-01-01 00:00:00

abstract：:This report presents the ultrastructural nerve study of a patient with sensorimotor neuropathy by a shoe glue containing an association of n-hexane and methylethylketone. Giant axons, distended by microfilamentous proliferation typical of such cases of neuropathy, were found in significant amounts. An unusual histolog...

journal_title：Acta neuropathologica

authors： Vallat JM,Leboutet MJ,Loubet A,Piva C,Dumas M

更新日期：1981-01-01 00:00:00

abstract：:The authors present the case of a hypertensive patient with a thrombosis of a saccular microaneurysm (SMA) and underlying cerebral (pontine) lacunae. This SMA lay at the junction between the main vessel and two small feeding arteries penetrating into the necrotic territory. Microhemorrhages were observed in and outsid...

journal_title：Acta neuropathologica

authors： Benhaiem-Sigaux N,Gherardi R,Salama J,Gray F,Amouroux J,Poirier J

更新日期：1986-01-01 00:00:00

abstract：:Rats were given isoniazid either in a single large dose or continuously in drinking water and killed 5--105 days later. The distribution of degenerating fibres in various nerves (sensory and mixed) and in various sites along nerves and spinal roots was studied by light and electron microscopy. It was found that sensor...

journal_title：Acta neuropathologica

authors： Jacobs JM,Miller RH,Cavanagh JB

更新日期：1979-10-01 00:00:00

abstract：:A giant-cell glioblastoma was examined by electron microscopy and by the freeze-fracture technique. The cell membranes bordering the extensive extracellular space often showed complicated undulations and peripheral vacuoles as well as occasional microvilli or filopodia. The undulations were mainly composed of plasmale...

journal_title：Acta neuropathologica

authors： Tani E,Nakano M,Itagaki T,Fukumori T

更新日期：1978-01-19 00:00:00

abstract：:An ultrastructural study was performed on normal and Benzo(a)-pyrene(B(a)P)-transformed fetal mouse brain cells. Early subcultures of a strain initiated from whole brain presented three cell types in vitro: astroglial, poorly differentiated glial, and spongioblastic types. After B(a)P-treatment, there was an exclusive...

journal_title：Acta neuropathologica

authors： Tripier MF,Markovits P,Papadopoulo D,Toga M

更新日期：1979-08-01 00:00:00

abstract：:A complex neuropathological study of two cases of Niemann-Pick disease (NPD) type C (NPDC) revealed some novel features in the chemical pathology of the neuronal storage. Lipid histochemistry showed the presence of a lipid which met the criteria of a neuronal glycosphingolipid. Sphingomyelin (SM) was not detected in t...

journal_title：Acta neuropathologica

authors： Elleder M,Jirásek A,Smíd F,Ledvinová J,Besley GT

更新日期：1985-01-01 00:00:00

abstract：:We examined the immunohistochemical localization of the proinflammatory cytokines tumor necrosis factor-alpha, lymphotoxin and interferon-gamma in 22 autopsy brains of patients with either cerebrovascular disease (CVD) or other neurological diseases as well as 2 non-neurological control brains. These cytokines were co...

journal_title：Acta neuropathologica

authors： Tomimoto H,Akiguchi I,Wakita H,Kinoshita A,Ikemoto A,Nakamura S,Kimura J

更新日期：1996-09-01 00:00:00

abstract：:The spinal cord of 20 patients with amyotrophic lateral sclerosis (ALS) and 5 patients with lower motor neuron disease (LMND) were investigated immunohistochemically using anti-human excitatory amino acid transporter 1 (EAAT1) and EAAT2 antibodies which are the astrocytic transporters. The purpose of the study was to ...

journal_title：Acta neuropathologica

authors： Sasaki S,Komori T,Iwata M

更新日期：2000-08-01 00:00:00

abstract：:The blood-brain barrier (BBB) was studied in rats with electrolyte-induced demyelination (EID), an experimental model for central pontine myelinolysis. Intravenously injected peroxidase was extravasated at 3 h post hypertonic saline injection (PHS) into regions frequently involved in EID. Increased pinocytotic activit...

journal_title：Acta neuropathologica

authors： Rojiani AM,Prineas JW,Cho ES

更新日期：1994-01-01 00:00:00

abstract：:A case of 14-year-old girl is reported in whom an alveolar rhabdomyosarcoma occurred in the soft tissues of the left forearm 4 years prior to death. Despite extensive surgery as well as chemotherapy and radiotherapy the tumor recurred locally and produced extensive metastases including a metastasis to the brain. Cereb...

journal_title：Acta neuropathologica

authors： Kleinert R,Beham A,Rosanelli G

更新日期：1985-01-01 00:00:00

abstract：:Accumulation of the tau protein in fibrillar intracellular aggregates is a defining feature of multiple neurodegenerative diseases collectively referred to as tauopathies. Despite intensive study of tau, there is limited information on the formation and clearance dynamics of tau inclusions. Using rAAV vectors to media...

journal_title：Acta neuropathologica

authors： Croft CL,Goodwin MS,Ryu DH,Lessard CB,Tejeda G,Marrero M,Vause AR,Paterno G,Cruz PE,Lewis J,Giasson BI,Golde TE

更新日期：2021-01-26 00:00:00

abstract：:Cerebellar torpedoes, unique fusiform swellings of Purkinje cell axons within the granular layer, have been known to occur sparsely associated with diffuse cerebellar changes. This report describes, in three human autopsy cases with focal necrotic lesions in the cerebellar white matter, torpedoes which were essentiall...

journal_title：Acta neuropathologica

authors： Takahashi N,Iwatsubo T,Nakano I,Machinami R

更新日期：1992-01-01 00:00:00

abstract：:Cryostat sections of 12 gliomas and of 3 peritumoral brain tissue samples were investigated for mononuclear cell infiltration by immunohistochemistry, concentrating on cells expressing monocyte/macrophage markers. Only low numbers of T cells were detected in the tumors, whereas in average 20%-30% of all cells present ...

journal_title：Acta neuropathologica

authors： Morimura T,Neuchrist C,Kitz K,Budka H,Scheiner O,Kraft D,Lassmann H

更新日期：1990-01-01 00:00:00

abstract：:In G93A mice, the most popular model of amyotrophic lateral sclerosis (ALS), neuronal Lewy-body-like hyaline inclusions (LBHIs) and mitochondria-derived vacuoles are observed in addition to motor neuron loss. Although LBHIs are thought to be toxic, the significance of the mitochondria-derived vacuoles has not been ful...

journal_title：Acta neuropathologica

authors： Sumi H,Nagano S,Fujimura H,Kato S,Sakoda S

更新日期：2006-07-01 00:00:00

abstract：:The colonic enteric nervous system was investigated in autopsy specimens from 12 patients with familial amyloidotic neuropathy (FAP) and 9 controls. The infiltration of amyloid deposits in the enteric nervous system was studied by double staining for amyloid and nerve elements. The myenteric plexus was immunostained f...

journal_title：Acta neuropathologica

authors： Anan I,El-Salhy M,Ando Y,Forsgren S,Nyhlin N,Terazaki H,Sakashita N,Suhr OB

更新日期：1999-07-01 00:00:00

abstract：:The spatial patterns of diffuse, primitive, classic (cored) and compact (burnt-out) subtypes of beta/A4 deposits were studied in coronal sections of the frontal lobe and hippocampus, including the adjacent gyri, in nine cases of Alzheimer's disease (AD). If the more mature deposits were derived from the diffuse deposi...

journal_title：Acta neuropathologica

authors： Armstrong RA,Myers D,Smith CU

更新日期：1993-01-01 00:00:00

abstract：:Uniform neuropathological changes are described in eight cases of the progressive encephalopathy syndrome with edema, hypsarrhythmia and optic atrophy (PEHO syndrome). Two of the autopsied patients were sisters and two other cases were familial. Macroscopically, cerebral and pronounced cerebellar atrophy was seen, the...

journal_title：Acta neuropathologica

authors： Haltia M,Somer M

更新日期：1993-01-01 00:00:00

abstract：:The character of the silver positive reticulin network was analyzed with immunofluorescence and immunoperoxidase methods in an intra vitam diagnosed case of primary brain lymphoma. The network was shown to contain connective tissue proteins rich in hexose-sugars, such as type III collagen (classical "reticulin"), basa...

journal_title：Acta neuropathologica

authors： Kalimo H,Lehto M,Näntö-Salonen K,Jalkanen M,Risteli L,Risteli J,Narva EV

更新日期：1985-01-01 00:00:00

abstract：:Microglia are long-living resident immune cells of the brain, which secure a stable chemical and physical microenvironment necessary for the proper functioning of the central nervous system (CNS). These highly dynamic cells continuously scan their environment for pathogens and possess the ability to react to damage-in...

journal_title：Acta neuropathologica

authors： Dudvarski Stankovic N,Teodorczyk M,Ploen R,Zipp F,Schmidt MHH

更新日期：2016-03-01 00:00:00

abstract：:Progressive myopathy developed in two women who consumed ipecac syrup containing emetine hydrochloride to induce vomiting as part of their anorexia nervosa. Muscle biopsy specimens were characterized by severe disruption of the sarcomeres. The ultrastructural spectrum extended from "Z-band streaming" to the formation ...

journal_title：Acta neuropathologica

authors： Halbig L,Gutmann L,Goebel HH,Brick JF,Schochet S

更新日期：1988-01-01 00:00:00

abstract：:Eleven atypical teratoid/rhabdoid tumors (AT/RT) and 121 primitive neuroectodermal tumors/medulloblastomas (PNET/MB) were included in this study for evaluation of the histopathological features of AT/RT and comparison between AT/RT and PNET/MB. Histopathological studies of AT/RT showed that in addition to the commonly...

journal_title：Acta neuropathologica

authors： Ho DM,Hsu CY,Wong TT,Ting LT,Chiang H

更新日期：2000-05-01 00:00:00

abstract：:We report an experimental model of Creutzfeldt-Jakob's disease (CJD) in mice leading to the formation of giant autophagic vacuoles (AV) in neurons of the cerebral cortex. These AV appear at the end of the incubation period (4-6 months postinoculation), together with spongy changes and clinical symptoms. Autophagy, a p...

journal_title：Acta neuropathologica

authors： Boellaard JW,Schlote W,Tateishi J

更新日期：1989-01-01 00:00:00

abstract：:The pathological changes in the nucleus basalis of Meynert (nbM) in 10 autopsied cases with Pick's disease were studied in comparison with 15 age-matched controls. Both the number and density of nerve cells and the degree of fibrillary gliosis were examined at the anterior, intermediate, and posterior divisions of the...

journal_title：Acta neuropathologica

authors： Mizukami K,Kosaka K

更新日期：1989-01-01 00:00:00

abstract：:A man of 75 years of age had had lightning pains in the legs for 8 years. Clinical examination demonstrated mild pyramidal signs and involvement of the posterior columns. A morphine pump was placed in the epidural space in the lumbar region to treat the pain. He died two weeks later from a massive pulmonary embolism. ...

journal_title：Acta neuropathologica

authors： Martin JJ,Cras P,De Schutter E

更新日期：1987-01-01 00:00:00

abstract：:The transmissible spongiform encephalopathies (TSEs) or prion diseases of animals are characterised by CNS spongiform change, gliosis and the accumulation of disease-associated forms of prion protein (PrP(d)). Particularly in ruminant prion diseases, a wide range of morphological types of PrP(d) depositions are found ...

journal_title：Acta neuropathologica

authors： Jeffrey M,McGovern G,Sisó S,González L

更新日期：2011-01-01 00:00:00

abstract：:This report deals with the expression of stress-response (heat-shock) protein 72 (srp 72) in a series of 95 primary human brain tumors and 21 carcinoma metastases to the central nervous system (CNS). Immunohistochemical procedures were employed; cells of the human cervical cancer line HeLa S3 were used as positive con...

journal_title：Acta neuropathologica

authors： Kato S,Hirano A,Kato M,Herz F,Ohama E

更新日期：1992-01-01 00:00:00

abstract：:Medulloblastoma (MB) represents approximately 4% of adult brain tumours, and as such is a poorly studied disease. Although many adult MB are treated using paediatric MB protocols, the reported outcomes are inferior to those observed in children. It remains unclear whether biologic differences underlie these clinical o...

journal_title：Acta neuropathologica

authors： Al-Halabi H,Nantel A,Klekner A,Guiot MC,Albrecht S,Hauser P,Garami M,Bognar L,Kavan P,Gerges N,Shirinian M,Roberge D,Muanza T,Jabado N

更新日期：2011-02-01 00:00:00

abstract：:Neurological signs were observed in 3 lambs at approximately 1 month of age, in a flock of 1 ram and 29 ewes with 43 lambs. Deterioration occurred such that the lambs had either died or been killed by 4 months of age. Necropsies of two of these lambs revealed a diffuse encephalopathy in which the most prominent featur...

journal_title：Acta neuropathologica

authors： Skelly BJ,Jeffrey M,Franklin RJ,Winchester BG

更新日期：1995-01-01 00:00:00

abstract：:Peroxiredoxin-ll (Prxll) and glutathione peroxidase-l (GPxl) are regulators of the redox system that is one of the most crucial supporting systems in neurons. This system is an antioxidant enzyme defense system and is synchronously linked to other important cell supporting systems. To clarify the common self-survival ...

journal_title：Acta neuropathologica

authors： Kato S,Kato M,Abe Y,Matsumura T,Nishino T,Aoki M,Itoyama Y,Asayama K,Awaya A,Hirano A,Ohama E

更新日期：2005-08-01 00:00:00