Bladder erosion by an intraperitoneal chemotherapy catheter resulting in catheter protrusion through the external urethral meatus.

abstract：OBJECTIVE:To evaluate the utility of combined positron emission tomography/computed tomography (PET/CT) for detecting recurrent epithelial ovarian cancer limited to retroperitoneal adenopathy. METHODS:Fourteen patients (median age = 53 years) with rising serum CA125 levels, and negative or equivocal conventional CT im...

journal_title：Gynecologic oncology

authors： Bristow RE,Giuntoli RL 2nd,Pannu HK,Schulick RD,Fishman EK,Wahl RL

更新日期：2005-11-01 00:00:00

abstract：PURPOSE:To examine the differentially expressed cancer-related genes in two morphologically different uterine cervical carcinoma cell lines derived from the same patient by an Affymetrix Human Cancer G110 Array carrying 1700 cancer-associated genes. In addition, to investigate specific gene expression depending on hist...

journal_title：Gynecologic oncology

authors： Fujimoto T,Nishikawa A,Iwasaki M,Akutagawa N,Teramoto M,Kudo R

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:An epigenetic approach to explaining endometrial carcinogenesis necessitates good understanding of Ras association domain family 1 isoform A (RASSF1A) promoter methylation data from primary studies. AIMS:Differential magnitude of reported associations between RASSF1A promoter methylation and endometrial can...

journal_title：Gynecologic oncology

authors： Pabalan N,Kunjantarachot A,Ruangpratheep C,Jarjanazi H,Christofolini DM,Barbosa CP,Bianco B

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:To investigate racial disparities with respect to adjuvant treatment and survival in patients presenting with malignant ovarian germ cell tumors (OGCT). METHODS:The National Cancer Database (NCDB) was used to identify women diagnosed with OGCT. Demographic data were abstracted, including stratification by ra...

journal_title：Gynecologic oncology

authors： Hinchcliff E,Rauh-Hain JA,Clemmer JT,Diver E,Hall T,Stall J,Growdon W,Clark R,Schorge J

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:In the last decade several studies have been published using proteomics to unravel molecular pathways and to find biomarkers which can be used for diagnosis and/or prognostication in ovarian cancer. This review gives an overview of proteomic studies performed in ovarian cancer focusing on the nature of sample...

journal_title：Gynecologic oncology

authors： Cadron I,Van Gorp T,Timmerman D,Amant F,Waelkens E,Vergote I

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:Randomized trials have demonstrated significant improvements in progression-free survival (PFS) with consolidation paclitaxel (P) and bevacizumab (B) following cytoreduction and adjuvant carboplatin/paclitaxel (CP) for advanced epithelial ovarian cancer (EOC). We sought to evaluate the cost-effectiveness (...

journal_title：Gynecologic oncology

authors： Lesnock JL,Farris C,Krivak TC,Smith KJ,Markman M

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Data has suggested obesity as an independent prognostic factor for lower survival in patients with epithelial ovarian cancer (EOC). We sought to determine if obesity portends a disadvantage to surgical outcomes at the time of initial surgery affecting survival. METHODS:A retrospective chart review of patient...

journal_title：Gynecologic oncology

authors： Matthews KS,Straughn JM Jr,Kemper MK,Hoskins KE,Wang W,Rocconi RP

更新日期：2009-02-01 00:00:00

abstract：:Adenocarcinoma originating in the endocervix may remain occult for many years. This may result in an extension to the uterine isthmus and corpus, with subsequent dissemination along the pathways of spread of uterine carcinoma, including metastasis to the ovaries. The patient described in this report had a bulky stage ...

journal_title：Gynecologic oncology

authors： Parham G,Heppard MC,DiSaia PJ

更新日期：1994-12-01 00:00:00

abstract：:Two cases of primary retroperitoneal mucinous cystoadenocarcinoma of the ovarian type are reported. Both tumors occurred in females with bilateral normal ovaries and contained benign, borderline, and malignant mucinous epithelium. Full-thickness infiltration of the cyst wall was not found. In addition to surgery, one ...

journal_title：Gynecologic oncology

authors： Tenti P,Carnevali L,Tateo S,Durola R

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:Our objective is to examine how selenium (Se) supplementation influences oxidative stress (malondialdehyde) and the glutathione peroxidase system in patients with ovarian cancer undergoing chemotherapy. MATERIAL:The study group included 31 patients with ovarian cancer undergoing chemotherapy receiving the dr...

journal_title：Gynecologic oncology

authors： Sieja K,Talerczyk M

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a classical glycolytic protein. A higher level of GAPDH mRNA was found in lung, pancreas, and prostate cancers, but in cervical carcinoma there have not been any reports about the level of GAPDH gene expression. So, we tried to investigate the GAPDH gene exp...

journal_title：Gynecologic oncology

authors： Kim JW,Kim SJ,Han SM,Paik SY,Hur SY,Kim YW,Lee JM,Namkoong SE

更新日期：1998-11-01 00:00:00

abstract：:The analysis of the lytic mechanism initiated by TNFalpha in three human ovarian cell lines (CAOV-3, SK-OV-3, and OVCAR-3) and in three human cervical cell lines (SIHa, HT-3, and ME-180) in the presence of inhibitors of protein synthesis indicates that this lytic mechanism is similar to the protein synthesis-independe...

journal_title：Gynecologic oncology

authors： Powell CB,Scott JH,Collins JL

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE(S):To determine whether antibiotic treatment (ABX) during platinum chemotherapy (PC) for epithelial ovarian cancer (EOC) impacts progression-free survival (PFS) and overall survival (OS). STUDY DESIGN:Retrospective single institution cohort study in women with newly diagnosed stage III/IV EOC (n = 424) who u...

journal_title：Gynecologic oncology

authors： Chambers LM,Kuznicki M,Yao M,Chichura A,Gruner M,Reizes O,Debernardo R,Rose PG,Michener C,Vargas R

更新日期：2020-12-01 00:00:00

abstract：:The optimal treatment of early-stage ovarian borderline tumors is controversial. Only a few randomized trials evaluating adjuvant treatment for this disease have been published. Between 1970 and 1988 four consecutive randomized trials, including patients with ovarian borderline tumors, were conducted at the Norwegian ...

journal_title：Gynecologic oncology

authors： Tropé C,Kaern J,Vergote IB,Kristensen G,Abeler V

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:To analyze corpus cancer patients with a breast cancer history for risk of developing aggressive uterine histologic types. METHODS:Corpus cancer patients with a history of breast cancer were identified from the Surveillance Epidemiology and End Results database from 1988 to 2001. Demographics, clinico-pathol...

journal_title：Gynecologic oncology

authors： Chan JK,Manuel MR,Cheung MK,Osann K,Husain A,Teng NN,Rao A,Carlson RW,Whittemore AS

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To describe our early experience with robotic-assisted laparoscopy for extraperitoneal para-aortic lymphadenectomy up to the left renal vein, including Da Vinci robot positioning. METHODS:Six patients underwent robotic-assisted laparoscopy using the Da Vinci apparatus. The patients included a man with a pT2 ...

journal_title：Gynecologic oncology

authors： Narducci F,Lambaudie E,Houvenaeghel G,Collinet P,Leblanc E

更新日期：2009-10-01 00:00:00

abstract：:Subgrouping of pelvic exenterations as supralevator (type I), infralevator (type II), with vulvectomy (type III), and, an added category, extended can be helpful to facilitate communication when referring to these patients. It also can facilitate a more detailed analysis of operative risk factors, complications, and r...

journal_title：Gynecologic oncology

authors： Magrina JF

更新日期：1990-06-01 00:00:00

abstract：OBJECTIVES:Laminin-5 is an attachment protein for epithelial cells. Several studies of a variety of cancers have reported increased expression of laminin-5 in carcinoma in situ and invasive cancer. This study was designed to investigate the correlation between the grade of cervical intraepithelial neoplasia and the imm...

journal_title：Gynecologic oncology

authors： Kohlberger P,Beneder Ch,Horvat R,Leodolter S,Breitenecker G

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the utility of DNA flow cytometry as a prognostic indicator for risk of recurrence and overall survival in patients with early stage adenocarcinomas of the uterine cervix. METHODS:DNA flow cytometry was performed to determine ploidy, DNA index, and proliferative ind...

journal_title：Gynecologic oncology

authors： Magtibay PM,Perrone JF,Stanhope CR,Katzmann JA,Keeney GL,Li H

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:The expression of homologous recombination (HR) genes in high grade ovarian cancer (HGOC) samples from debulking surgeries were correlated to outcomes in patients selected for chemotherapy treatment regimens. STUDY DESIGN:RNA was extracted from 96 fresh frozen tumor samples from debulking surgeries from chem...

journal_title：Gynecologic oncology

authors： Kessous R,Octeau D,Klein K,Tonin PN,Greenwood CMT,Pelmus M,Laskov I,Kogan L,Salvador S,Lau S,Yasmeen A,Gotlieb WH

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:In this study, we examine the sensitivity of a panel of ovarian carcinoma cells, which includes four primary ovarian cancer cell samples, and four normal ovarian epithelium samples to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). We also examine the intracellular regulation of TRAIL-mediat...

journal_title：Gynecologic oncology

authors： Lane D,Cartier A,L'Espérance S,Côté M,Rancourt C,Piché A

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:MKK4 is a metastasis suppressor that is downregulated in some ovarian cancers. We sought to investigate whether promoter methylation, loss of heterozygosity, or changes in phosphorylation are involved in MKK4 dysregulation during ovarian carcinogenesis. METHODS:Bisulfite sequencing was used to determine MKK...

journal_title：Gynecologic oncology

authors： Spillman MA,Lacy J,Murphy SK,Whitaker RS,Grace L,Teaberry V,Marks JR,Berchuck A

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:Chemotherapy is the preferred therapeutic approach for the therapy of advanced ovarian cancer, but a successful long-term treatment is prevented by the development of drug resistance. Recent works have underlined the involvement of non-coding RNAs, microRNAs (miRNAs) in cancer development, with several conje...

journal_title：Gynecologic oncology

authors： Sorrentino A,Liu CG,Addario A,Peschle C,Scambia G,Ferlini C

更新日期：2008-12-01 00:00:00

abstract：:The clinical-pathologic records of 178 women with stage IB squamous cell carcinoma treated by radical hysterectomy and pelvic node dissection were reviewed to assess prognostic factors and outcome in relation to adjunctive pelvic radiation. Among 32 women with pelvic nodes metastases, 19 treated with adjunctive radiat...

journal_title：Gynecologic oncology

authors： Remy JC,di Maio T,Fruchter RG,Sedlis A,Boyce JG,Sohn CK,Rotman M

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:One of the most active chemotherapy combinations in advanced or recurrent cervical cancer is cisplatin-paclitaxel. However, this palliative regimen is associated with significant toxicity. Carboplatin-paclitaxel is thus an attractive option. METHODS:Patients with advanced or recurrent carcinoma of the cervi...

journal_title：Gynecologic oncology

authors： Tinker AV,Bhagat K,Swenerton KD,Hoskins PJ

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:We conducted a case-control study to analyze risk factors for ovarian cancer. METHODS:Cases included 440 women (age range 13-80 years, median 54) with a histologically confirmed diagnosis of epithelial ovarian cancer who were admitted to the Gynecological Oncological Department of Gynecologic Oncology at the...

journal_title：Gynecologic oncology

authors： Greggi S,Parazzini F,Paratore MP,Chatenoud L,Legge F,Mancuso S,La Vecchia C

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:The effect on progesterone and estrogen receptor expression in glands and stroma after two different treatment regimens of endometrial hyperplasia was determined. METHODS:Pre- and post-treatment paraffin-embedded endometrial hyperplasia specimens from women treated with levonorgestrel (LNG) intrauterine dev...

journal_title：Gynecologic oncology

authors： Vereide AB,Kaino T,Sager G,Arnes M,Ørbo A

更新日期：2006-05-01 00:00:00

abstract：:PI3K/AKT/mTOR pathway is a crucial mediator of tumor progression. As the PI3K/Akt pathway is heavily deregulated in breast cancer, the application of mTOR inhibitors in breast cancer patients seems warranted. This is the first systematic review according to PRISMA guidelines to synthesize all available data of mTOR in...

journal_title：Gynecologic oncology

authors： Zagouri F,Sergentanis TN,Chrysikos D,Filipits M,Bartsch R

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:The efficacy and safety of bevacizumab and docetaxel were evaluated in women who developed recurrent epithelial ovarian, fallopian, or peritoneal cancer within 12 months of platinum-based therapy. METHODS:Patients received docetaxel (40 mg/m(2)) on days 1 and 8 and bevacizumab (15 mg/kg) on day 1 of a 21-da...

journal_title：Gynecologic oncology

authors： Wenham RM,Lapolla J,Lin HY,Apte SM,Lancaster JM,Judson PL,Gonzalez-Bosquet J,Herschberger A,Havrilesky LJ,Secord AA

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:The aim of our study was to retrospectively examine the proliferating cell nuclear antigen (PCNA) immunoreactivity of tumor cells in curettage specimens containing endometrioid adenocarcinoma and obtained immediately before definitive surgical staging. This PCNA index was compared with the one subsequently de...

journal_title：Gynecologic oncology

authors： Garzetti GG,Ciavattini A,Goteri G,De Nictolis M,Romanini C

更新日期：1996-04-01 00:00:00