Intracellular mechanism of action of isoflurane and halothane on striated muscle of the rabbit.

abstract：BACKGROUND:In patients undergoing total knee arthroplasty under spinal anesthesia, we compared the postoperative analgesic effect of intraoperative sedation with dexmedetomidine versus propofol. We hypothesized that sedation with dexmedetomidine would result in lower postoperative opioid analgesic consumption than with...

journal_title：Anesthesia and analgesia

authors： Shin HJ,Do SH,Lee JS,Kim TK,Na HS

更新日期：2019-12-01 00:00:00

abstract：UNLABELLED:Nonpharmacologic techniques may be effective in preventing postoperative nausea and vomiting (PONV). This sham-controlled, double-blinded study was designed to examine the antiemetic efficacy of transcutaneous acupoint electrical stimulation (TAES) in a surgical population at high risk of developing PONV. We...

journal_title：Anesthesia and analgesia

authors： Zárate E,Mingus M,White PF,Chiu JW,Scuderi P,Loskota W,Daneshgari V

更新日期：2001-03-01 00:00:00

abstract：UNLABELLED:Cryoanalgesia versus sham treatment was applied to the ilioinguinal and iliohypogastric nerves after mesh repair of an inguinal hernia under local anesthesia in 48 male patients in a prospective, randomized, and observer- and patient-blinded trial. Pain was scored daily during rest, while coughing, and durin...

journal_title：Anesthesia and analgesia

authors： Callesen T,Bech K,Thorup J,Andersen J,Nielsen R,Roikjaer O,Kehlet H

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Increasing evidence links postoperative cognitive dysfunction (POCD) to surgery and anesthesia. POCD is recognized as an important neuropsychological adverse outcome in surgical patients, particularly the elderly. This prospective cohort study aimed to investigate whether POCD is associated with impaired int...

journal_title：Anesthesia and analgesia

authors： Goettel N,Burkhart CS,Rossi A,Cabella BC,Berres M,Monsch AU,Czosnyka M,Steiner LA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Blood conservation strategies and transfusion guidelines remain a heavily debated clinical topic. Previous investigational trials have shown that acute isovolemic hemodilution does not limit adequate oxygen delivery; however, a true critical hemoglobin level has never been investigated or defined due to safe...

journal_title：Anesthesia and analgesia

authors： Sims CR 3rd,Delima LR,Calimaran A,Hester R,Pruett WA

更新日期：2018-01-01 00:00:00

abstract：UNLABELLED:We evaluated the pretreatment of small-dose of ketamine or normal saline in the reduction of withdrawal movements induced by rocuronium injection. One-hundred pediatric patients (aged 1-6 yr) were randomly assigned into 2 groups. A 22-gauge IV cannula was inserted into the dorsum of the hand, and ketamine 0....

journal_title：Anesthesia and analgesia

authors： Liou JT,Hsu JC,Liu FC,Ching-Wah Sum D,Lui PW

更新日期：2003-11-01 00:00:00

abstract：:The purpose of the present study was to assess patients' anxiety level and information requirement in the preoperative phase. During routine preoperative screening, 320 patients were asked to assess their anxiety and information requirement on a six-item questionnaire, the Amsterdam Preoperative Anxiety and Informatio...

journal_title：Anesthesia and analgesia

authors： Moerman N,van Dam FS,Muller MJ,Oosting H

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Surveys suggest that, consistent with a high smoking prevalence, Chinese smokers in the general population report little interest in quitting. In other cultures, surgery is a powerful teachable moment for smoking cessation, increasing the rate of spontaneous quitting. We determined the perioperative tobacco ...

journal_title：Anesthesia and analgesia

authors： Yu C,Shi Y,Kadimpati S,Sheng Y,Jing J,Schroeder D,Luo A,Warner DO

更新日期：2013-06-01 00:00:00

abstract：UNLABELLED:alpha(2) Adrenoceptor activity is involved in the mechanism of anesthesia. Clonidine, a alpha(2) adrenoceptor agonist, and yohimbine, a alpha(2) adrenoceptor antagonist, increase and decrease barbiturate-induced sleep times. In this study, we examined the effects of these drugs on propofol-induced sleep time...

journal_title：Anesthesia and analgesia

authors： Kushikata T,Hirota K,Yoshida H,Kubota T,Ishihara H,Matsuki A

更新日期：2002-05-01 00:00:00

abstract：:A pharmacokinetic evaluation of bupivacaine was carried out after intercostal nerve blocks performed on 28 occasions in 27 children varying in age from 3 months to 16 yr. Bupivacaine HCl, 0.5%, with epinephrine 1:200,000 was employed. Doses of 2 mg/kg, 3 mg/kg, and 4 mg/kg resulted in peak whole blood arterial bupivac...

journal_title：Anesthesia and analgesia

authors： Rothstein P,Arthur GR,Feldman HS,Kopf GS,Covino BG

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:We have previously reported that hemorrhagic shock decreases the minimum alveolar anesthetic concentration (MAC) of isoflurane but minimally alters the electroencephalographic (EEG) effect. In this study, we investigated the influence of endotoxemia on the EEG effect and the MAC of isoflurane. METHODS:Eight...

journal_title：Anesthesia and analgesia

authors： Kurita T,Takata K,Morita K,Uraoka M,Sato S

更新日期：2010-01-01 00:00:00

abstract：UNLABELLED:Recent reports have discussed the potential risk of transient radicular irritation (TRI) after spinal anesthesia with lidocaine. Because we have not encountered such neurologic sequelae with the high incidence reported, we prospectively examined the incidence of TRI after spinal anesthesia with lidocaine. On...

journal_title：Anesthesia and analgesia

authors： Morisaki H,Masuda J,Kaneko S,Matsushima M,Takeda J

更新日期：1998-05-01 00:00:00

abstract：:Although clonidine has been shown to increase the duration of local anesthetic action and prolong postoperative analgesia when included in single-injection nerve blocks, the only controlled investigation of the efficacy of this practice to improve analgesia for continuous perineural local anesthetic infusion failed to...

journal_title：Anesthesia and analgesia

authors： Ilfeld BM,Morey TE,Thannikary LJ,Wright TW,Enneking FK

更新日期：2005-04-01 00:00:00

abstract：UNLABELLED:The Valsalva maneuver in the awake patient and the ventilation maneuver in the tracheally intubated anesthetized patient are two provocation methods to detect a patent foramen ovale (PFO) by means of contrast transesophageal echocardiography. In 60 patients undergoing posterior fossa surgery, a contrast agen...

journal_title：Anesthesia and analgesia

authors： Greim CA,Trautner H,Krämer K,Zimmermann P,Apfel CC,Roewer N

更新日期：2001-05-01 00:00:00

abstract：UNLABELLED:The visual analog scale (VAS) has been used to assess the efficacy of pain management regimens in patients with acute postoperative pain, but its usefulness has not been confirmed in postoperative pain studies. We studied 60 subjects in the immediate postoperative period. The specific data collected were: VA...

journal_title：Anesthesia and analgesia

authors： DeLoach LJ,Higgins MS,Caplan AB,Stiff JL

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The α2-adrenergic agonist dexmedetomidine is a sedative and can be used as an adjunct to anesthetics. Our primary goal was thus to determine the extent to which dexmedetomidine reduces the requirement for propofol and remifentanil. METHODS:This double-blinded, randomized study (NCT00921284) used an automate...

journal_title：Anesthesia and analgesia

authors： Le Guen M,Liu N,Tounou F,Augé M,Tuil O,Chazot T,Dardelle D,Laloë PA,Bonnet F,Sessler DI,Fischler M

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Respiratory complications were associated with half of pediatric malpractice claims from the 1970s to 1980s in the ASA Closed Claims Database. Advances in pediatric anesthesia practice have occurred in the 1980s and 1990s and may be reflected in liability trends. METHODS:We reviewed 532 pediatric (age < or ...

journal_title：Anesthesia and analgesia

authors： Jimenez N,Posner KL,Cheney FW,Caplan RA,Lee LA,Domino KB

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a "lighter" depth of sedation. Among these strategies are "analgosedation" protocols, which prioritize pain management and preferentially use IV opioids before administration of continuously...

journal_title：Anesthesia and analgesia

authors： Faust AC,Rajan P,Sheperd LA,Alvarez CA,McCorstin P,Doebele RL

更新日期：2016-10-01 00:00:00

abstract：UNLABELLED:Chronic ingestion of small doses of ethanol protects the myocardium from ischemic damage. It was demonstrated that short-term administration of ethanol (SAE) enhances the recovery of stunned myocardium in acutely instrumented, anesthetized dogs. It is unclear whether this beneficial effect of SAE also occurs...

journal_title：Anesthesia and analgesia

authors： Weber TP,Hartlage MA,Rolf N,Booke M,Berendes E,Van Aken H,Meissner A

更新日期：2003-03-01 00:00:00

abstract：:The alpha 2-adrenergic receptor agonist dexmedetomidine produces an anesthetic state in a variety of species. Although its effects on cerebral blood flow and the electroencephalogram have been investigated, the effect of this drug on intracranial pressure (ICP) has not been reported previously. Dexmedetomidine therefo...

journal_title：Anesthesia and analgesia

authors： Zornow MH,Scheller MS,Sheehan PB,Strnat MA,Matsumoto M

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Visualization with ultrasound during regional anesthesia may reduce the risk of intraneural injection and subsequent neurological symptoms but has not been formally assessed. Thus, we performed this randomized clinical trial comparing ultrasound versus nerve stimulator-guided interscalene blocks for shoulder...

journal_title：Anesthesia and analgesia

authors： Liu SS,Zayas VM,Gordon MA,Beathe JC,Maalouf DB,Paroli L,Liguori GA,Ortiz J,Buschiazzo V,Ngeow J,Shetty T,Ya Deau JT

更新日期：2009-07-01 00:00:00

abstract：:The purpose of the present study was to quantify the inhibitory effect of inhaled halothane and isoflurane on acute hypercapnia-induced responses of capacitance-regulating veins and related cardiovascular variables in response to sequential 40-s periods of 5%, 10%, 15%, and 20% inspired CO2 (FICO2). Measurements were ...

journal_title：Anesthesia and analgesia

authors： Stekiel TA,Stekiel WJ,Tominaga M,Stadnicka A,Bosnjak ZJ,Kampine JP

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Modulation of γ-aminobutyric acid type A receptors (GABAARs) by general anesthetics may contribute to their ability to produce amnesia. Receptors containing α5 subunits, which mediate tonic and slow synaptic inhibition, are co-localized with β3 and γ2 subunits in dendritic layers of the hippocampus and are s...

journal_title：Anesthesia and analgesia

authors： Burkat PM,Lor C,Perouansky M,Pearce RA

更新日期：2014-12-01 00:00:00

abstract：UNLABELLED:Previous studies of samples from cranial meninges have created doubts about the existence of a virtual subdural space. We examined the ultrastructure of spinal meninges from three human cadavers immediately after death to see whether there is a virtual subdural space at this level. The arachnoid mater had tw...

journal_title：Anesthesia and analgesia

authors： Reina MA,De Leon Casasola O,López A,De Andrés JA,Mora M,Fernández A

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:The primary objective of this study was to compare the characteristics of culture-positive and culture-negative status in septic patients. We also determined whether culture status is associated with mortality and whether unique variables are associated with mortality in culture-positive and culture-negative...

journal_title：Anesthesia and analgesia

authors： Sigakis MJG,Jewell E,Maile MD,Cinti SK,Bateman BT,Engoren M

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:In this study, we evaluated the efficacy of celiac plexus block for the treatment of feeding intolerance in critically ill patients. METHODS:Nineteen mechanically ventilated medical patients intolerant of enteral nutrition and receiving metoclopramide underwent bilateral celiac plexus block. The anterior pr...

journal_title：Anesthesia and analgesia

authors： Memis D,Inal MT,Temizoz O,Genchallac H,Ozdemir H,Sut N

更新日期：2010-04-01 00:00:00

abstract：UNLABELLED:N-methyl-D-aspartate receptor antagonism probably accounts for most of ketamine's anesthetic effects; its analgesic properties are mediated partly via N-methyl-D-aspartate and partly via opioid receptors. We assessed the involvement of the mu-opioid receptor in S(+) ketamine-induced respiratory depression an...

journal_title：Anesthesia and analgesia

authors： Sarton E,Teppema LJ,Olievier C,Nieuwenhuijs D,Matthes HW,Kieffer BL,Dahan A

更新日期：2001-12-01 00:00:00

abstract：:To evaluate the effect of propranolol on anesthetic requirement, changes in minimum alveolar concentration (MAC) of halothane accompanying acute (2 and 10 mg/kg IV) and chronic (200 mg/day orally for 10 days) propranolol administration were determined in dogs. MAC did not change significantly in either case. Beta-adre...

journal_title：Anesthesia and analgesia

authors： Tanifuji Y,Eger EI II

更新日期：1976-05-01 00:00:00

abstract：:Sufentanil is a new synthetic opiate analgesic that is 4520 times more potent than morphine in animal experiments. This study evaluated the cardiovascular effects of sufentanil, 15 micrograms/kg, and air/O2 used as a complete anesthetic with 50% inspired oxygen (air/O2 mixture) in 40 adult patients undergoing elective...

journal_title：Anesthesia and analgesia

authors： Sebel PS,Bovil JG

更新日期：1982-02-01 00:00:00

abstract：IMPLICATIONS:In this study, although 41%-94% of the patients were fast-track eligible after laparoscopic surgery, only 35%-53% of the patients actually bypassed the postanesthesia care unit (PACU) because of anesthetic-related factors and surgical complications. Residual sedation was the most common anesthetic-related ...

journal_title：Anesthesia and analgesia

authors： Coloma M,Zhou T,White PF,Markowitz SD,Forestner JE

更新日期：2001-07-01 00:00:00