Energy dispersive X-ray diffraction study of phase development during hardening of calcium phosphate bone cements with addition of chitosan.

abstract：:Thin films of amorphous carbon and amorphous, graphitic and fullerene-like carbon nitride were deposited by reactive magnetron sputtering and optically characterized with spectroscopic ellipsometry. Complementary studies using scanning electron microscopy and atomic force microscopy were performed. The films were expo...

journal_title：Acta biomaterialia

authors： Berlind T,Tengvall P,Hultman L,Arwin H

更新日期：2011-03-01 00:00:00

abstract：:Nanotherapeutic strategy is well recognized as the therapeutic approach of the future. Numerous reports have demonstrated the use of nanoparticulate drug carriers for the development of targeted nanotherapeutics by, for instance, incorporation of a moiety that specifically targets certain diseased cells. However, syst...

journal_title：Acta biomaterialia

authors： Tung WL,Hu SH,Liu DM

更新日期：2011-07-01 00:00:00

abstract：:Functional and perfusable vascular network formation is critical to ensure the long-term survival and functionality of engineered tissues after their transplantation. Although several vascularization strategies have been reviewed in past, the significance of microvessel organization in three-dimensional (3D) scaffolds...

journal_title：Acta biomaterialia

authors： Sharma D,Ross D,Wang G,Jia W,Kirkpatrick SJ,Zhao F

更新日期：2019-09-01 00:00:00

abstract：UNLABELLED:Cellular microenvironments present cells with multiple stimuli, including not only soluble biochemical and insoluble matrix cues but also mechanical factors. Biomaterial array platforms have been used to combinatorially and efficiently probe and define two-dimensional (2D) and 3D microenvironmental cues to g...

journal_title：Acta biomaterialia

authors： Liu H,Usprech J,Sun Y,Simmons CA

更新日期：2016-04-01 00:00:00

abstract：:The suitability of porous silicon (pSi) encapsulated in microfibers of the biodegradable polymer polycaprolactone (PCL) for ophthalmic applications was evaluated, using both a cell attachment assay with epithelial cells and an in vivo assessment of biocompatibility in rats. Microfibers of PCL containing encapsulated p...

journal_title：Acta biomaterialia

authors： Kashanian S,Harding F,Irani Y,Klebe S,Marshall K,Loni A,Canham L,Fan D,Williams KA,Voelcker NH,Coffer JL

更新日期：2010-09-01 00:00:00

abstract：:Although novel molecular targeted drugs have been recognized as an effective therapy for non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) activating mutations, their efficacy fails to meet the expectation due to the acquired resistance in tumors. Up-regulation of the anti-apoptotic ...

journal_title：Acta biomaterialia

authors： Lv T,Li Z,Xu L,Zhang Y,Chen H,Gao Y

更新日期：2018-08-01 00:00:00

abstract：:The goal of this study was to evaluate three-dimensional (3-D) poly(ethylene glycol) (PEG) hydrogels as a culture system for studying corneal keratocytes. Bovine keratocytes were subcultured in DMEM/F-12 containing 10% fetal bovine serum (FBS) through passage 5. Primary keratocytes (P0) and corneal fibroblasts from pa...

journal_title：Acta biomaterialia

authors： Garagorri N,Fermanian S,Thibault R,Ambrose WM,Schein OD,Chakravarti S,Elisseeff J

更新日期：2008-09-01 00:00:00

abstract：:Light curable methacrylate dental monomers containing reactive calcium phosphate filler (monocalcium phosphate monohydrate (MCPM) with particle diameter of 29 or 90microm) and beta-tricalcium phosphate (beta-TCP) at 1:1 weight ratio in a powder:liquid ratio (PLR) of 1:1 or 3:1 and chlorhexidine diacetate (0 or 5 wt.%)...

journal_title：Acta biomaterialia

authors： Mehdawi I,Neel EA,Valappil SP,Palmer G,Salih V,Pratten J,Spratt DA,Young AM

更新日期：2009-09-01 00:00:00

abstract：UNLABELLED:The development of scaffolds for bone filling of large defects requires an understanding of angiogenesis and vascular guidance, which are crucial processes for bone formation and healing. There are few investigations on the ability of a scaffold to support blood vessel guidance and it this is of great import...

journal_title：Acta biomaterialia

authors： Magnaudeix A,Usseglio J,Lasgorceix M,Lalloue F,Damia C,Brie J,Pascaud-Mathieu P,Champion E

更新日期：2016-07-01 00:00:00

abstract：:Dicalcium phosphate cements (brushite and monetite) are resorbable biomaterials with osteoconductive potential for bone repair and regeneration that have yet to gain widespread commercial use. Brushite can be converted to monetite by heat treatments additionally resulting in various changes in the physico-chemical pro...

journal_title：Acta biomaterialia

authors： Sheikh Z,Zhang YL,Tamimi F,Barralet J

更新日期：2017-04-15 00:00:00

abstract：:Decellularized extracellular matrix (ECM) has been widely used for tissue engineering applications and is becoming increasingly versatile as it can take many forms, including patches, powders, and hydrogels. Following additional processing, decellularized ECM can form an inducible hydrogel that can be injected, provid...

journal_title：Acta biomaterialia

authors： Spang MT,Christman KL

更新日期：2018-03-01 00:00:00

abstract：:Abdominal aortic aneurysms (AAAs), a prototypic proteolytic cardiovascular disorder, are localized expansions of the aortal wall. Chronically upregulated and overexpressed proteases irreversibly degrade and disrupt the elastic matrix, which provides stretch and recoil properties to the aortal wall. Adult vascular smoo...

journal_title：Acta biomaterialia

authors： Camardo A,Carney S,Ramamurthi A

更新日期：2020-08-01 00:00:00

abstract：:The antimicrobial properties of silver and copper nanoparticles were investigated using Escherichia coli (four strains), Bacillus subtilis and Staphylococcus aureus (three strains). The average sizes of the silver and copper nanoparticles were 3 nm and 9 nm, respectively, as determined through transmission electron mi...

journal_title：Acta biomaterialia

authors： Ruparelia JP,Chatterjee AK,Duttagupta SP,Mukherji S

更新日期：2008-05-01 00:00:00

abstract：:A three-dimensional (3-D) cell culture system that allows control of both substrate stiffness and integrin binding density was created and characterized. This system consisted of two self-assembling peptide (SAP) sequences that were mixed in different ratios to achieve the desired gel stiffness and adhesiveness. The s...

journal_title：Acta biomaterialia

authors： Stevenson MD,Piristine H,Hogrebe NJ,Nocera TM,Boehm MW,Reen RK,Koelling KW,Agarwal G,Sarang-Sieminski AL,Gooch KJ

更新日期：2013-08-01 00:00:00

abstract：:In this study, we report the synthesis of novel environmentally responsive polyurea hydrogel networks prepared via organic sol-gel chemistry and demonstrate that the networks can stabilize pH while releasing glucose both in simple aqueous media and in mammalian cell culture settings. Hydrogel formulations have been de...

journal_title：Acta biomaterialia

authors： Patil S,Chaudhury P,Clarizia L,McDonald M,Reynaud E,Gaines P,Schmidt DF

更新日期：2012-08-01 00:00:00

abstract：UNLABELLED:Type I collagen is widely applied as a biomaterial for tissue regeneration. In the extracellular matrix, collagen provides strength but not elasticity under large deformations, a characteristic crucial for dynamic organs and generally imparted by elastic fibers. In this study, a methodology is described to i...

journal_title：Acta biomaterialia

authors： Versteegden LR,Hoogenkamp HR,Lomme RM,van Goor H,Tiemessen DM,Geutjes PJ,Oosterwijk E,Feitz WF,Hafmans TG,Verdonschot N,Daamen WF,van Kuppevelt TH

更新日期：2016-10-15 00:00:00

abstract：:The mechanical properties of Bombyx mori silk fibroin (SF), such as elasticity and tensile strength, change remarkably upon hydration. However, the microscopic interaction with water is not currently well understood on a molecular level. In this work, the dynamics of water molecules interacting with SF was studied by ...

journal_title：Acta biomaterialia

authors： Asakura T,Isobe K,Kametani S,Ukpebor OT,Silverstein MC,Boutis GS

更新日期：2017-03-01 00:00:00

abstract：:The geometric features of bone graft substitutes, such as the pore and pore interconnection sizes, are of paramount importance for their biological performance. Such features are generally characterized by micro-computed tomography (μCT). Unfortunately, the resolution of μCT is often too limited. The aim of this study...

journal_title：Acta biomaterialia

authors： Bashoor-Zadeh M,Baroud G,Bohner M

更新日期：2011-11-01 00:00:00

abstract：:A new class of injectable and erodible hydrogels exhibiting highly robust gel strength at body temperature was fabricated by enzyme-mediated cross-linking between Pluronic copolymer micelles. Tyramine-conjugated Pluronic F-127 tri-block copolymers at two terminal ends of polyethylene oxide (PEO) side chains were synth...

journal_title：Acta biomaterialia

authors： Lee SH,Lee Y,Lee SW,Ji HY,Lee JH,Lee DS,Park TG

更新日期：2011-04-01 00:00:00

abstract：:Understanding the influence of a controlled spatial distribution of biological cues on cell activities can be useful to design "cell instructive" materials, able to control and guide the formation of engineered tissues in vivo and in vitro. To this purpose, biochemical and mechanical properties of the resulting biomat...

journal_title：Acta biomaterialia

authors： Guarnieri D,De Capua A,Ventre M,Borzacchiello A,Pedone C,Marasco D,Ruvo M,Netti PA

更新日期：2010-07-01 00:00:00

abstract：:Mesoporous materials are of high interest as implant coatings to receive an enhanced osseointegration. In this study, titanium implants coated with mesoporous TiO(2) thin films have been evaluated both in vitro and in vivo. Material characterization showed that, with partly crystalline TiO(2) (anatase), long-range-ord...

journal_title：Acta biomaterialia

authors： Karlsson J,Jimbo R,Fathali HM,Schwartz-Filho HO,Hayashi M,Halvarsson M,Wennerberg A,Andersson M

更新日期：2012-12-01 00:00:00

abstract：:In humans, high level of collagen remodeling is seen during normal physiological events such as bone renewal, as well as in pathological conditions, such as arthritis, tumor growth and other chronic wounds. Our lab recently discovered that collagen mimetic peptide (CMP) is able to hybridize with denatured collagens at...

journal_title：Acta biomaterialia

authors： Chan TR,Stahl PJ,Li Y,Yu SM

更新日期：2015-03-01 00:00:00

abstract：:The effect of calcium phosphate-based microchannels on the growth and orientation of human osteoblast cells is investigated in this study. As substrates, hydroxyapatite-based microchannels with high contouring accuracy were fabricated by a novel micro-moulding technique. Microchannels obtained by this method featured ...

journal_title：Acta biomaterialia

authors： Holthaus MG,Stolle J,Treccani L,Rezwan K

更新日期：2012-01-01 00:00:00

abstract：:To reduce the biocorrosion rate by surface modification, Mg-Ca alloy (1.4wt.% Ca content) was soaked in three alkaline solutions (Na(2)HPO(4), Na(2)CO(3) and NaHCO(3)) for 24h, respectively, and subsequently heat treated at 773K for 12h. Scanning electron microscopy and energy-dispersive spectroscopy results revealed ...

journal_title：Acta biomaterialia

authors： Gu XN,Zheng W,Cheng Y,Zheng YF

更新日期：2009-09-01 00:00:00

abstract：:Chitosan was functionalized with imidazole moieties (CHimi) with the aim of improving its buffering capacity and promoting the endosomal escape ability of chitosan-DNA complexes, ultimately increasing their transfection efficiency. 5.6%, 12.9% and 22.1% of the glucosamine residues of chitosan were substituted. Complex...

journal_title：Acta biomaterialia

authors： Moreira C,Oliveira H,Pires LR,Simões S,Barbosa MA,Pêgo AP

更新日期：2009-10-01 00:00:00

abstract：:Aseptic loosening of total joint replacements is driven by a macrophage-mediated inflammatory reaction to implant-derived wear particles. Phagocytosis of implant debris has been suggested to activate the NLRP3 inflammasome leading to secretion of interleukin (IL)-1β. However, factors and molecular mechanisms driving t...

journal_title：Acta biomaterialia

authors： Jämsen E,Pajarinen J,Kouri VP,Rahikkala A,Goodman SB,Manninen M,Nordström DC,Eklund KK,Nurmi K

更新日期：2020-05-01 00:00:00

abstract：:The functional requirements of regenerated calcified tissues are that they enable the tissues to bear a variety of imposed stress and consequent contact-induced strain without substantial fracture. Here we demonstrate the effects of glucocorticoid hormones such as dexamethasone and hydrocortisone on the nanomechanical...

journal_title：Acta biomaterialia

authors： Miyamoto S,Miyamoto Y,Shibata Y,Yoshimura K,Izumida E,Suzuki H,Miyazaki T,Maki K,Kamijo R

更新日期：2015-01-01 00:00:00

abstract：:This study characterizes the cross-linking of electrospun elastin and the mechanical properties of suture-reinforced 1.5mm internal diameter electrospun tubes composed of blended polydioxanone (PDO) and soluble elastin. Several tube configurations were tested to assess the effects of reinforcement on tube mechanical p...

journal_title：Acta biomaterialia

authors： Smith MJ,McClure MJ,Sell SA,Barnes CP,Walpoth BH,Simpson DG,Bowlin GL

更新日期：2008-01-01 00:00:00

abstract：:A series of six unique Ca-based bulk metallic glasses were synthesized and characterized. The glasses were designed to consist solely of the biocompatible elements Ca, Mg and Zn, with the view to their potential use as bioresorbable metals for orthopaedic applications. The alloys had a critical casting thickness of up...

journal_title：Acta biomaterialia

authors： Cao JD,Kirkland NT,Laws KJ,Birbilis N,Ferry M

更新日期：2012-07-01 00:00:00

abstract：:Our objectives were to correlate the mineral density (MD) and elastic modulus (E) of natural white spot lesions (WSLs) and compare them with analytical and numerical models. Five natural WSLs from four extracted sound premolar teeth were scanned at a voxel size of 7.6μm using a desktop X-ray microtomography (XRMT) sys...

journal_title：Acta biomaterialia

authors： Huang TT,He LH,Darendeliler MA,Swain MV

更新日期：2010-12-01 00:00:00