Abstract：
:In vivo suppression of prolactin concentrations by bromocriptine near term, in a pregnant woman with a prolactinoma, was followed by augmentation of human chorionic gonadotropin levels. Suspension of drug therapy at 38 weeks of gestation was followed by a reversal of this sequence of events. In vitro, both ovine prolactin and human prolactin added to explants of term placental trophoblast significantly inhibited human chorionic gonadotropin production from this tissue. Although, with ovine prolactin, this inhibitory effect was demonstrable up to 5 micrograms/ml of ovine prolactin in the culture medium, only doses of 0.1 to 0.2 micrograms/ml of human prolactin significantly suppressed human chorionic gonadotropin production. Overall, 0.1 and 0.2 micrograms/ml of ovine prolactin and human prolactin most consistently suppressed human chorionic gonadotropin production to a statistically significant extent. In general, the concentrations in the culture medium of both ovine prolactin and human prolactin that inhibited human chorionic gonadotropin production in vitro were comparable to the concentrations of prolactin present in the mother and fetus. These in vivo and in vitro observations suggest that prolactin inhibits human chorionic gonadotropin production from term human trophoblast.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
Yuen BH,Moon YS,Shin DHdoi
10.1016/0002-9378(86)90667-8subject
Has Abstractpub_date
1986-02-01 00:00:00pages
336-40issue
2eissn
0002-9378issn
1097-6868pii
0002-9378(86)90667-8journal_volume
154pub_type
杂志文章abstract：OBJECTIVE:The purpose of this study was to evaluate changes in cerebral blood perfusion and middle cerebral artery (MCA) Doppler in full-term small-for-gestational-age fetuses (SGA) and to explore their association with neonatal neurobehavioral performance. STUDY DESIGN:Frontal brain perfusion that was measured by fra...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2009.05.028
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:Complex oncologic surgeries, including those for endometrial cancer, increasingly have been concentrated to greater-volume centers, owing to previous research that has demonstrated associations between greater surgical volume and improved outcomes. There is a potential for concentration of care to have unwan...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2019.07.026
更新日期：2020-01-01 00:00:00
abstract：:Prolactin levels in amniotic fluid during the third trimester of human pregnancy showed a wide range of values. There was no apparent correlation between amniotic fluid prolactin concentrations (AF PRL) and lecithin/sphingomyelin (L/S) ratios nor was there a prolactin concentration associated with a mature L/S ratio. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(81)90321-5
更新日期：1981-02-15 00:00:00
abstract：:Nifedipine, a dihydropyridone calcium entry blocker, has been used with increasing frequency in the treatment of preterm labor. We studied 66 patients in this prospective, randomized trial to evaluate the efficacy and maternal, fetal, and neonatal outcome associated with tocolysis with nifedipine or ritodrine. Deliver...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9378(11)90679-6
更新日期：1990-07-01 00:00:00
abstract：:This is the first case of a 65 year old healthy woman developing de novo mental confusion during treatment with 2 mg tolterodine twice daily. It is a rare complication of therapy for overactive bladder and resolved when dosage was reduced to 1 mg, although overactive bladder symptoms were still controlled. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2007.04.051
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Randomized controlled trials that have assessed the efficacy of cervical pessary to prevent preterm birth in asymptomatic high-risk women have reported conflicting results. OBJECTIVE:To evaluate the efficacy and safety of cervical pessary to prevent preterm birth and adverse perinatal outcomes in asymptomat...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,meta分析
doi：10.1016/j.ajog.2019.12.266
更新日期：2020-07-01 00:00:00
abstract：:The first reported case of recurrent acute fatty liver of pregnancy confirmed by biopsy is described. In this case a high index of suspicion led to an early diagnosis and intervention with resultant improved maternal and fetal outcome. Electron microscopic examination of a liver biopsy specimen proved more beneficial ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(90)91191-e
更新日期：1990-08-01 00:00:00
abstract：:The effect of an intravenous bolus of 25 mg of conjugated estrogen (Premarin) on vaginal blood flow in seven surgically menopausal women was measured by a thermal conductance probe. Electrical power (0.8 W) was supplied to a resistance wire incorporated in the surface of the probe, and its surface temperature was moni...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(82)90075-8
更新日期：1982-06-15 00:00:00
abstract：:Although previous studies have suggested that the breech infant weighing less than 1,500 gm benefits from cesarean section, the published results have not demonstrated statistically significant differences. We have evaluated pediatric outcome data for 240 breech infants and 525 vertex infants who weighed less than 1,5...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(83)90807-4
更新日期：1983-07-01 00:00:00
abstract：:A case report of hemolytic uremic syndrome with placental involvement in 2 of 3 consecutive pregnancies highlights the impact on the fetal placental compartment and the importance of diligent antenatal care in subsequent pregnancies. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2001.116829
更新日期：2001-11-01 00:00:00
abstract：OBJECTIVE:We sought to study neonatal outcomes in early preterm births by delivery route. STUDY DESIGN:Delivery precursors were analyzed in 4352 singleton deliveries, 24 0/7 to 31 6/7 weeks' gestation. In a subset (n = 2906) eligible for a trial of labor, neonatal mortality in attempted vaginal delivery (VD) was compa...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2012.06.023
更新日期：2012-08-01 00:00:00
abstract：:Prostacyclin is a potent vasodilator produced by both maternal and fetal tissues that dilates the umbilical placental vasculature in vitro. To test the hypothesis that prostacyclin dilates the fetal placental circulation in vivo, we measured blood flow by the radioactive microsphere technique in six unanesthetized nea...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(89)90303-7
更新日期：1989-04-01 00:00:00
abstract：OBJECTIVE:The objective of the study was a cost minimization analysis of the laparoscopic sacral colpopexy (LSC) and total vaginal mesh (TVM). STUDY DESIGN:Primary clinical costs were derived from our randomized control trial comparing LSC and TVM and were compared using prices from privately- and publicly-conducted p...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajog.2011.12.012
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVE:A metaanalysis of randomized trials was conducted to evaluate if the type of hysterectomy, total abdominal hysterectomy or supracervical hysterectomy, has an impact on the development of urinary incontinence. STUDY DESIGN:We searched MEDLINE, EMBASE, CINAHL, Biological Abstract, and the Cochrane Library up t...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,meta分析
doi：10.1016/j.ajog.2007.09.033
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVE:This study aims to determine the prevalence of physical activity and obesity and their relationship to physical functioning (PF), fatigue, and pain in endometrial cancer survivors. STUDY DESIGN:Surveys were mailed to 200 survivors of endometrial cancer diagnosed within the last 5 years; 61% were returned. Su...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2008.10.010
更新日期：2009-03-01 00:00:00
abstract：:Responses of the component tissues of the nonpregnant ovine uterus to intravenous administration of norepinephrine were determined with radioactively labeled microspheres under flowmeter guidance. During a mean decrease in uterine conductance to 42 per cent of control, no significant differences in the distribution of...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1978-08-01 00:00:00
abstract：:The mechanisms whereby estradiol retards ovum transport through the rabbit oviduct were investigated. 40 controls were given intravenous injections of 100 units of human chorionic gonadotropin (HCG). (Ovulation follows injection by 10-14 hours.) 24 hours after injection 20 controls were sacrificed; a 90.5% recovery...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(73)91043-0
更新日期：1973-05-15 00:00:00
abstract：OBJECTIVE:Our purpose was to determine whether women with polycystic ovary syndrome have greater subclinical atherosclerosis as measured by carotid artery ultrasonography. STUDY DESIGN:Sixteen premenopausal women > or = 40 years old with a history of clinical polycystic ovary syndrome and a current total testosterone ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(96)70665-8
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVE:The objectives of this study were to determine whether insulin autoantibodies are present in umbilical cord blood from normal pregnancies, determine whether cord blood insulin autoantibody levels correlate with respective maternal levels at delivery, determine whether cord blood insulin autoantibody levels ar...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(95)90445-x
更新日期：1995-12-01 00:00:00
abstract：:As part of a multicenter prospective study, second-trimester human chorionic gonadotropin and alpha-fetoprotein concentrations were evaluated. Data included maternal age, human chorionic gonadotropin level, alpha-fetoprotein level, weight, race, and pregnancy outcome of 3428 pregnancies at between 15 and 20 weeks' ges...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(91)90305-b
更新日期：1991-09-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to evaluate which variables predict neonatal depression in vaginal deliveries that result in permanent brachial plexus injury. STUDY DESIGN:With the use of a data set of litigated vaginal deliveries (n = 103 deliveries) from 1978 through 1999 that resulted in permanent brachial ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2002.127128
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVE:Various tocolytics are used to suppress uterine contractility in patients in preterm labor. Progesterone (P4) is used in patients at high risk for preterm delivery. In this study, we evaluated the effects of various tocolytics with and without P4 to examine effects on uterine contractility. STUDY DESIGN:Uter...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2011.12.011
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:There are a number of poor birth outcomes with advancing maternal age. Although there is some evidence of a higher risk of trauma to obstetric anal sphincter and the levator ani muscle with advancing age, findings to date are inconclusive. OBJECTIVE:The aim of this study was to assess the risk of pelvic flo...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2016.04.032
更新日期：2016-10-01 00:00:00
abstract：:This study was designed to test the hypothesis that maternal marijuana smoking impairs placental oxygen transfer in late ovine pregnancy by disrupting perfusion balance between the maternal and fetal placental circulations. Placental hemodynamics were assessed in nine chronically prepared ewes 1 hour after exposure to...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(88)90569-8
更新日期：1988-12-01 00:00:00
abstract：OBJECTIVE:We examined intraplacental color Doppler flow patterns and spectral Doppler flow velocity waveforms of villous arteries in pregnancies with intrauterine growth retardation. STUDY DESIGN:A total of 192 uncomplicated pregnancies and 29 pregnancies with intrauterine growth retardation between 26 and 41 weeks' g...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(94)90143-0
更新日期：1994-11-01 00:00:00
abstract：OBJECTIVE:Increased understanding of human parturition allows for novel approaches to (1) identification of women at increased risk for preterm birth and (2) development and controlled testing of etiology-based strategies to prevent preterm birth. STUDY DESIGN:Five hundred forty-two women were enrolled at five study s...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/0002-9378(95)91383-1
更新日期：1995-10-01 00:00:00
abstract：OBJECTIVE:To analyze the effects of preconception maternal height and weight on the risk of preterm singleton and twin births resulting from in vitro fertilization (IVF). STUDY DESIGN:We performed a retrospective cohort analysis of the incidence of very early preterm birth (VEPTB), early preterm birth (EPTB), and pret...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2013.05.052
更新日期：2013-10-01 00:00:00
abstract：:A study was made of the relationship of proton T1 relaxation times and stage of the menstrual cycle. Preliminary data show that these indicators of red blood cell hydration status may be useful as objective markers of premenstrual tension. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(85)90358-8
更新日期：1985-12-01 00:00:00
abstract：OBJECTIVE:Our purpose was to determine amniotic fluid volume by the dye-dilution technique and compare it with the amniotic fluid index, largest vertical pocket, and two-diameter pocket (defined as vertical x horizontal of the largest vertical pocket). STUDY DESIGN:This prospective study involved 40 women undergoing a...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(92)91734-r
更新日期：1992-12-01 00:00:00
abstract：:Two types of fibrous structures can be demonstrated in midcycle cervical mucus: (1) long, thick fibers that vary in diameter from 0.5 to 5 mum and run parallel to each other, and (2) microfibrils that vary in diameter from 500 to 1,500 A and form bundles or networks. The spaces in such networks usually measure from 8...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(75)90065-4
更新日期：1975-07-01 00:00:00
