Chinchilla "big" and "little" gastrins.

abstract：:Adipose tissue-derived stem cells (ADSCs), which are easily harvested and show excellent pluripotency potential, have generated considerable interest in regenerative medicine. In this study, the differentiation of ADSCs was assessed after treatment with dental follicle cell conditioned medium (DFCCM) containing dentin...

journal_title：Biochemical and biophysical research communications

authors： Wen X,Nie X,Zhang L,Liu L,Deng M

更新日期：2011-06-10 00:00:00

abstract：BACKGROUND:Membrane protrusions play important roles in biological processes such as cell adhesion, wound healing, migration, and sensing of the external environment. Cell protrusions are a subtype of membrane microdomains composed of cholesterol and sphingolipids, and can be disrupted by cholesterol depletion. Promini...

journal_title：Biochemical and biophysical research communications

authors： Singh RD,Schroeder AS,Scheffer L,Holicky EL,Wheatley CL,Marks DL,Pagano RE

更新日期：2013-05-10 00:00:00

abstract：:Surfactant convertase is required for conversion of heavy density (H) natural surfactant to light density (L) subtype during cycling in vitro, a technique that reproduces surfactant metabolism. To study mechanisms of H to L conversion, we prepared liposomes of dipalmitoylphosphatidylcholine (DPPC) and phosphatidylglyc...

journal_title：Biochemical and biophysical research communications

authors： Dhand R,Sharma VK,Teng AL,Krishnasamy S,Gross NJ

更新日期：1998-03-27 00:00:00

abstract：:Bile acids have recently emerged as key metabolic hormones with beneficial impacts in multiple metabolic diseases. We previously discovered that hepatic bile acid overload distally modulates glucose and fatty acid metabolism in adipose tissues to exert anti-obesity effects. However, the detailed mechanisms that explai...

journal_title：Biochemical and biophysical research communications

authors： Lee SH,Choi JM,Jung SY,Cox AR,Hartig SM,Moore DD,Kim KH

更新日期：2021-01-01 00:00:00

abstract：:The expression of sucrase-isomaltase mRNA was investigated along the crypt-villus axis of rat small intestine using differentially isolated cells and in situ hybridization. A partial rat sucrase-isomaltase cDNA was cloned which coded for a protein that was predicted to be 88% homologous to those encoded by the rabbit ...

journal_title：Biochemical and biophysical research communications

authors： Traber PG

更新日期：1990-12-31 00:00:00

abstract：:The origins and developmental regulation of cerebellar oligodendrocytes are largely unknown, although some hypotheses of embryonic origins have been suggested. Neural stem cells exist in the white matter of postnatal cerebellum, but it is unclear whether these neural stem cells generate oligodendrocytes at postnatal s...

journal_title：Biochemical and biophysical research communications

authors： Naruse M,Shibasaki K,Ishizaki Y

更新日期：2015-08-07 00:00:00

abstract：:The Sir proteins, namely Sir2, 3 and 4, have roles related to heterochromatin, but genome-wide studies have revealed their presence at many euchromatic loci, although the functional meaning of this is still not clear. Nhp6a is an abundant HMG-like protein in yeast, which has a role in transcription by modulating chrom...

journal_title：Biochemical and biophysical research communications

authors： Ciuffetta A,Salerno D,Camilloni G,Venditti S

更新日期：2015-05-22 00:00:00

abstract：:A polyamine derivative, carboxyethyl - Aminobutyric Acid (CEGABA), induces the formation of a large number of Epstein-Barr Virus (EBV) transformed lymphocytes, when added to the culture medium immediately after EBV infection. However, CEGABA shows only a moderate effect on the stability of EBV-transformed cell lines o...

journal_title：Biochemical and biophysical research communications

authors： Cerino A,Bestagno M,Colonna M,Fussi F,Astaldi Ricotti GC

更新日期：1988-02-15 00:00:00

abstract：:Green tea catechins have been shown to attenuate obesity in animals and humans. The catechins activate adenosine monophosphate-activated protein kinase (AMPK), and thereby increase fatty acid oxidation in liver and skeletal muscles. Green tea catechins have also been shown to reduce body fat in humans. However, the ef...

journal_title：Biochemical and biophysical research communications

authors： Chen S,Osaki N,Shimotoyodome A

更新日期：2015-05-22 00:00:00

abstract：PURPOSE:Recently, the newly identified embryonic stem cell marker, Zinc finger and SCAN domain containing 4 gene (ZSCAN4), which plays a key role in genomic stability by regulating telomere elongation, was shown to co-localize with TRF1 foci. This suggests that the interaction of ZSCAN4 with TRF1 functions in regulatio...

journal_title：Biochemical and biophysical research communications

authors： Lee K,Gollahon LS

更新日期：2015-10-30 00:00:00

abstract：:Irradiation induces severe damage in the hematopoietic system, which leads to bone marrow hyperplasia, pancytopenia, and aggravated tissue formation in bone marrow. Studies have shown that Toll-like receptor 4 (TLR4) has a protective effect against irradiation, but the underlying mechanism remains unclear. In this stu...

journal_title：Biochemical and biophysical research communications

authors： Sun Z,Wu K,Lin Q,Fei H,Jiang H,Chen T,Yuan Y

更新日期：2019-12-03 00:00:00

abstract：:Our previous study indicates that hyperinsulinemia in metabolic syndrome in the absence of nephropathy may promote hypertension by stimulating renal proximal tubule (PT) sodium transport via insulin receptor substrate (IRS) 2/phosphoinositide 3-kinase pathway. In the present study we showed that the stimulatory effect...

journal_title：Biochemical and biophysical research communications

authors： Nakamura M,Satoh N,Suzuki M,Kume H,Homma Y,Seki G,Horita S

更新日期：2015-05-22 00:00:00

abstract：:Tumor necrosis factor-alpha (TNFα) is a multifunctional cytokine associated with inflammation, immune responses, and autoimmune diseases including rheumatoid arthritis, inflammatory bowel disease, and psoriasis. In the present study, we performed in vitro selection, systematic evolution of ligands by exponential enric...

journal_title：Biochemical and biophysical research communications

authors： Tsukamoto K,Ando T,Fuji D,Yokoyama T,Takamori Y,Horiuchi D,Iwamoto R,Yamamoto M,Kawakami T

更新日期：2021-01-01 00:00:00

abstract：:The effect of immune interferon (IFN-gamma) and recombinant tumor necrosis factor (rTNF-alpha) on cellular differentiation was investigated in human promyelocytic leukemia cell line HL-60. Both IFN-gamma and rTNF-alpha induced the appearance of the monocytic phenotype in a dose- and time-dependent manner as assessed b...

journal_title：Biochemical and biophysical research communications

authors： Glazer RI,Chapekar MS,Hartman KD,Knode MC

更新日期：1986-11-14 00:00:00

abstract：:Internal backbone dynamic motions are essential for different protein functions and occur on a wide range of time scales, from femtoseconds to seconds. Molecular dynamic (MD) simulations and nuclear magnetic resonance (NMR) spin relaxation measurements are valuable tools to gain access to fast (nanosecond) internal mo...

journal_title：Biochemical and biophysical research communications

authors： Liu Q,Shi C,Yu L,Zhang L,Xiong Y,Tian C

更新日期：2015-02-13 00:00:00

abstract：:maf is a family of oncogenes, originally identified from the avian oncogenic retrovirus AS42, which encodes a nuclear bZip transcription factor protein. It has been reported that maf family genes have critical roles in embryological development and cellular differentiation. In this study, the distribution of maf-1 gen...

journal_title：Biochemical and biophysical research communications

authors： Imaki J,Onodera H,Tsuchiya K,Imaki T,Mochizuki T,Mishima T,Yamashita K,Yoshida K,Sakai M

更新日期：2000-06-16 00:00:00

abstract：:The delta subunit of the epithelial sodium channel (δENaC) is a member of the ENaC/degenerin family of ion channels. δENaC is distinct from the related α-, β- and γENaC subunits, known for their role in sodium homeostasis and blood pressure control, as δENaC is expressed in brain neurons and activated by external prot...

journal_title：Biochemical and biophysical research communications

authors： Chang T,Ke Y,Ly K,McDonald FJ

更新日期：2011-08-05 00:00:00

abstract：:Retroviral gene transfer of dominant selectable markers into hematopoietic cells can be used to select genetically modified cells in vivo or to attenuate the toxic effects of chemotherapeutic agents. We show that retroviral gene transfer of thymidylate synthase (TS) confers resistance to TS directed anticancer agents ...

journal_title：Biochemical and biophysical research communications

authors： Fantz CR,Shaw D,Moore JG,Spencer HT

更新日期：1998-02-04 00:00:00

abstract：:Docetaxel efficiency in the therapy of prostate cancer (PCa) patients is limited due to the development of chemoresistance. Recent studies have implied a role of INPP4B in tumor chemoresistance, while the effects of INPP4B on docetaxel resistance in PCa have not been elucidated. In the present study, the docetaxel-res...

journal_title：Biochemical and biophysical research communications

authors： Chen H,Li H,Chen Q

更新日期：2016-08-26 00:00:00

abstract：:To analyse the species of genes expressed in a cleavage stage mouse embryo, we have constructed a cDNA library containing 3.0 x 10(5) independent clones from about 2 x 10(3) embryos at the 8-cell stage of development. Endo A cDNA prepared from parietal yolk sac endoderm like PYS-2 cells was used to screen the library....

journal_title：Biochemical and biophysical research communications

authors： Nozaki M,Murata K,Morita T,Matsushiro A

更新日期：1988-08-15 00:00:00

abstract：:Atmospheric oxygen is important for the epidermis, as the skin epidermis is not greatly affected by blood circulation. Therefore, it is necessary to understand the effect of hypoxic signals on the epidermis as some environmental stimuli can induce skin hypoxia. Here, we investigated how hypoxia (1% O2) affected skin e...

journal_title：Biochemical and biophysical research communications

authors： Park JY,Jung JY,Kim HJ,Bae IH,Kim DY,Lee TR,Shin DW

更新日期：2016-01-08 00:00:00

abstract：:We have examined the kinetics of the effects of inhibitors of the Na+/H(+)-antiporter (dimethylamiloride) and the vacuolar H(+)-ATPase (bafilomycin A1) on bone resorption by disaggregated rat osteoclasts in the bone slice assay. Bafilomycin A1 (100 nM) inhibited resorption by approximately 95%, 75%, 80% and 60% respec...

journal_title：Biochemical and biophysical research communications

authors： Hall TJ,Schaeublin M,Chambers TJ

更新日期：1992-11-16 00:00:00

abstract：:The effect of platelet release products on cytosolic calcium [( Ca++]i) was examined by monitoring the fluorescence of chick embryonic heart cells loaded with the fluorescent calcium indicator indo-1 AM. Cell free filtrate of platelet release products was obtained from rabbit platelets activated with thrombin or colla...

journal_title：Biochemical and biophysical research communications

authors： Chien WW,Mohabir R,Newman D,Leung LL,Clusin WT

更新日期：1990-08-16 00:00:00

abstract：:Linoleic acid, an omega-6 unsaturated fatty acid, stimulated growth of the MDA-MB-231 and MCF-7 human breast cancer cell lines in culture. Responses of the estrogen-independent MDA-MB-231 cells both in serum-free medium and with 1% fetal bovine serum added were positively correlated with linoleic acid concentration ov...

journal_title：Biochemical and biophysical research communications

authors： Rose DP,Connolly JM

更新日期：1989-10-16 00:00:00

abstract：:Elevated Na(+) concentration ([Na(+)]) in the cerebrospinal fluid (CSF) contributes to the development of salt-sensitive hypertension. CSF is formed by the choroid plexus (CP) in cerebral ventricles, and [Na(+)] in CSF is controlled by transporters in CP. Here, we examined the effect of high salt diet on the expressio...

journal_title：Biochemical and biophysical research communications

authors： Guo L,Meng J,Xuan C,Ge J,Sun W,O'Rourke ST,Sun C

更新日期：2015-05-29 00:00:00

abstract：:Thyroid hormone (T3) responsiveness of the PEPCK promoter in vivo was examined in both PEPCK/bGH(460) and PEPCK/bGH(335) mouse lines. Transgenic and non-transgenic littermates were treated with methimazole or PTU for 6 or 4 weeks, respectively, then treated +/- T3 for 10 days. In PEPCK/bGH(460) and PEPCK/bGH(355) tran...

journal_title：Biochemical and biophysical research communications

authors： Xu C,McGrane MM

更新日期：1996-01-17 00:00:00

abstract：:The previously reported substrate-heme complex approach is used to study the binding of type II inhibitors of the enzyme cholesterol side chain cleavage (CSCC), a cytochrome P-450 dependent enzyme involved in the oxidative cleaveage of the C(20)-C(22) bond of cholesterol. Using the derived model, we have rationalised ...

journal_title：Biochemical and biophysical research communications

authors： Ahmed S

更新日期：2000-08-11 00:00:00

abstract：:Fatty Acid Synthase (FASN), a 250-kDa cytosolic multi-enzyme catalyzing eukaryotic de novo FA biogenesis, unexpectedly localizes in cancer cell culture supernatants and in the blood of cancer patients. High levels of "extracellular FASN" have recently been found in supernatants from Hepatitis C Virus-infected liver ce...

journal_title：Biochemical and biophysical research communications

authors： Oliveras-Ferraros C,Vazquez-Martin A,Fernández-Real JM,Menendez JA

更新日期：2009-01-16 00:00:00

abstract：:Human umbilical cord-derived mesenchymal stromal cells (hUC-MSCs) in vitro expansion for long term may undergo epigenetic and genetic alterations that subsequently induce cellular senescence and associated growth inhibition. Increasing evidence implicated that aberrant histone acetylation modulates gene expression res...

journal_title：Biochemical and biophysical research communications

authors： Li Y,Zhong H,Wu M,Tan B,Zhao L,Yi Q,Xu X,Pan H,Bi Y,Yang K

更新日期：2019-07-12 00:00:00

abstract：:The production of recombinant hepatitis B virus surface antigen (rHBsAg) purified by immunoaffinity chromatography with monoclonal antibodies is used to obtain a vaccine against this virus. Monoclonal antibodies to rHBsAg from mouse ascites have been purified by Staphylococcal Protein A (SpA)--prior coupling to Sephar...

journal_title：Biochemical and biophysical research communications

authors： Valdés Veliz R,García J,Reyes B,Muñoz L,Alvarez T,Padilla S,Abrahantes Mdel C,Zubiaurrez J,Agraz A,Marrero A

更新日期：2003-04-11 00:00:00