Cis-platinum (CDDP) plus etoposide (VP-16-213) and treatment of disseminated neuroblastoma.

abstract：BACKGROUND:Postoperative pancreatic fistula (POPF) remains a major complication after pancreaticoduodenectomy (PD), and the prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) after PD is poor. PATIENTS AND METHODS:A multi-institutional retrospective study was performed in 174 patients who underwent PD ...

journal_title：Anticancer research

authors： Yamashita Y,Yoshizumi T,Fukuzawa K,Nishizaki T,Tsujita E,Kajiyama K,Soejima Y,Yamagata M,Yamamoto K,Adachi E,Sugimachi K,Ikeda Y,Uchiyama H,Maeda T,Itoh S,Harimoto N,Ikegami T,Maehara Y

更新日期：2016-05-01 00:00:00

abstract：:Chronic lymphocytic leukaemia remains the most common adult leukaemia in Western countries. In this review we tried to give an overview of the important prognostic markers and the developments in this field. We also reflected about the accumulative character of the disease and the influence of the micro-environment on...

journal_title：Anticancer research

authors： Boelens J,Lust S,Vanhoecke B,Offner F

更新日期：2009-02-01 00:00:00

abstract：:A clearly benign parotid tumor, an adenolymphoma, was studied cytogenetically using short-term cultured material. The first preparation showed only a normal stemline. The two subsequent preparations were both characterized by a pseudodiploid stemline with the karyotype 46,XY,del(7) (p12p14-15), t(11;19) (q21;p12-13). ...

journal_title：Anticancer research

authors： Mark J,Dahlenfors R,Stenman G,Nordquist A

更新日期：1989-11-01 00:00:00

abstract：:Small cell lung cancer (SCLC) cells express cholinergic nicotinic receptors on their membranes, and the stimulatory effect on cell growth of nicotine has been described in cell cultures. We investigated three SCLC cell lines, all showing high levels of fluorescence intensity when labeled with FITC alpha-bungarotoxin i...

journal_title：Anticancer research

authors： Pratesi G,Cervi S,Balsari A,Bondiolotti G,Vicentini LM

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:In order to develop a multi-marker RT-PCR, which as such may be more sensitive than a single marker assay for the detection of disseminated tumor cells, we evaluated six RT-PCR markers: cytokeratin 20 (CK20), carcinoembryonic antigen (CEA), guanylyl cyclase C (GCC), epidermal growth factor receptor (EGFR), m...

journal_title：Anticancer research

authors： Vlems FA,Diepstra JH,Cornelissen IM,Ligtenberg MJ,Wobbes T,Punt CJ,van Krieken JH,Ruers TJ,van Muijen GN

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Human herpesviruses types 4 and 6 (EBV, HHV-6) are frequently found in Hodgkin 's disease (HD) and--to a certain extent--in Kikuchi-Fujimoto's disease (KFD). Both viruses are apparently related to proliferative and/or apoptotic processes as represented by HD or KFD respectively. OBJECTIVE:To correlate frequ...

journal_title：Anticancer research

authors： Krueger GR,Huetter ML,Rojo J,Romero M,Cruz-Ortiz H

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Taxane-based chemotherapy is useful for peritoneal dissemination control in advanced/recurrent gastric cancer; however, insufficient relative dose intensity (RDI) may preclude disease control achievement. Nab-paclitaxel, with high tumour permeability, is a promising second- or later-line treatment. PATIENTS...

journal_title：Anticancer research

authors： Kanazawa Y,Fujita I,Kakinuma D,Arai H,Matsuno K,Shimoda T,Ko K,Kato S,Uchida E

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Nucleotide-binding domain and leucine-rich repeat-containing family, pyrin domain-containing 7 (NLRP7) (pyrin-containing apoptotic protease activating factor-1-like protein 3; PYPAF3, NACHT domain-, leucine-rich repeat, and pyrin domain-containing 7; NALP7) has been thought to contribute to innate immunity a...

journal_title：Anticancer research

authors： Ohno S,Kinoshita T,Ohno Y,Minamoto T,Suzuki N,Inoue M,Suda T

更新日期：2008-07-01 00:00:00

abstract：:p63 expression was evaluated in a tissue microarray of prostate tissues including benign glands, prostatic intraepithelial neoplasia and prostatic carcinoma. Immunostaining with anti-p63 antibody was restricted to basal cell nuclei. Detectable p63 was found in immortalized and early passage cell cultures, but not in s...

journal_title：Anticancer research

authors： Davis LD,Zhang W,Merseburger A,Young D,Xu L,Rhim JS,Moul JW,Srivastava S,Sesterhenn IA

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The size of colorectal polyps is important in the clinical management of these lesions. When using a conventional ruler (the tool of pathologists worldwide), we have previously found unacceptably high intra- and inter-observer variations in assessing the size of phantom polyps. The aim of this study was to a...

journal_title：Anticancer research

authors： Suzuki C,Matsson L,Rubio CA

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Despite receiving post-operative 5-fluorouracil (5-FU)-based chemotherapy, approximately 50% of patients with stage IIIC colon cancer experience recurrence. Currently, no molecular signature can predict response to 5-FU. MATERIALS AND METHODS:Mouse models of colon cancer have been developed and characterize...

journal_title：Anticancer research

authors： Hadac JN,Miller DD,Grimes IC,Clipson L,Newton MA,Schelman WR,Halberg RB

更新日期：2016-03-01 00:00:00

abstract：AIM:To report our experience on implementation and preliminary results of a decision-making model based on the recommendations of an Interdisciplinary Oncological Care Group developed for the management of colorectal cancer. PATIENTS AND METHODS:The multidisciplinary team identified a reference guideline using apprais...

journal_title：Anticancer research

authors： Genovesi D,Mazzilli L,Trignani M,DI Tommaso M,Nuzzo A,Biondi E,Tinari N,Martino MT,Innocenti P,DI Sebastiano P,Mazzola L,Lanci C,Neri M,Laterza F,Marino M,Ferrini G,Spadaccini A,Filippone A,DI Giandomenico E,Marulli

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND/AIM:In patients with soft tissue sarcoma (STS), distinguishing small metastatic pulmonary nodules from benign ones remains difficult. This study aimed to determine the accuracy of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in detecting pulmonary metastasis and identi...

journal_title：Anticancer research

authors： Hagi T,Nakamura T,Sugino Y,Matsubara T,Asanuma K,Sudo A

更新日期：2018-06-01 00:00:00

abstract：:We generated a recombinant immunotoxin, named scFv(MGR6)-Cla, composed of the Fv region of an anti ErbB2 monoclonal antibody (MGR6) fused to clavin, a type 1 ribosome-inactivating protein (RIP) from Aspergillus clavatus. ErbB2 is a tyrosine kinase receptor which is overexpressed in most adenocarcinomas; clavin is a 17...

journal_title：Anticancer research

authors： D'Alatri L,Di Massimo AM,Anastasi AM,Pacilli A,Novelli S,Saccinto MP,De Santis R,Mele A,Parente D

更新日期：1998-09-01 00:00:00

abstract：:Recent studies have addressed the prevalence and prognostic impact of thrombocytosis in various gynecologic and non-gynecologic malignancies. Thrombocytosis appears to be of prognostic value in certain patients with gynecologic malignancies. In this survey we review the published data and attempt to analyze the progno...

journal_title：Anticancer research

authors： Gücer F,Tamussino K,Keil F,Balkanli-Kaplan P,Yüce MA

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND/AIM:In this study we aimed to determine if advanced age represents a risk factor for negative perioperative and long-term outcome in patients undergoing curative surgery ductal pancreatic adenocarcinoma surgery. PATIENTS AND METHODS:Two-hundred-twenty-one consecutive patients, twelve (6%) patients ≥80 years...

journal_title：Anticancer research

authors： Marsoner K,Kornprat P,Sodeck G,Schagerl J,Langeder R,Csengeri D,Wagner D,Mischinger HJ,Haybaeck J

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND/AIM:Chest radiotherapy (RT) doubles late cardiac mortality. This study aimed to evaluate the evolution of cardiac changes in speckle tracking echocardiography during a three-year follow-up. MATERIALS AND METHODS:This prospective study included 81 chemotherapy-naïve early-stage breast cancer patients who wer...

journal_title：Anticancer research

authors： Tuohinen SS,Skytta T,Huhtala H,Virtanen V,Kellokumpu-Lehtinen PL,Raatikainen P

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:A cross-sectional study was performed on a cohort of colorectal cancer (CRC) patients to reveal any influence of age, gender, and subsite on grades of malignancy. PATIENTS AND METHODS:Data from histopathological grading according to WHO criteria were pooled into groups of low-grade (well and moderately diff...

journal_title：Anticancer research

authors： Brozek W,Kriwanek S,Bonner E,Peterlik M,Cross HS

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:ProPSA has been suggested for the detection of preferentially aggressive prostate cancer (PCa). We report on the use of proPSA and free PSA to enhance preoperative staging and grading. PATIENTS AND METHODS:Serum samples from 376 PCa patients within the PSA range 1-25 microg/l who underwent radical prostatec...

journal_title：Anticancer research

authors： Stephan C,Meyer HA,Paul EM,Kristiansen G,Loening SA,Lein M,Jung K

更新日期：2007-07-01 00:00:00

abstract：:We examined the expression of survivin using immunohistochemistry in 102 cases of laryngeal squamous cell carcinoma (LSCC). Overall, 65.7% (67 out of 102) of tumors were positive for survivin expression and significantly associated with tumor site, poor differentiation, tumor size, lymph node metastasis and advanced s...

journal_title：Anticancer research

authors： Dong Y,Sui L,Watanabe Y,Sugimoto K,Tokuda M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND/AIM:Reportedly, hypertension tends to be associated with response to bevacizumab therapy, because bevacizumab suppresses vascular nitric oxide production. In this study we examined the predictive value of nitric oxide in bevacizumab-treated non-small cell lung cancer (NSCLC) patients. PATIENTS AND METHODS:F...

journal_title：Anticancer research

authors： Muto S,Takagi H,Owada Y,Inoue T,Watanabe Y,Yamaura T,Fukuhara M,Okabe N,Matsumura Y,Hasegawa T,Osugi J,Hoshino M,Higuchi M,Shio Y,Suzuki H

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND/AIM:Novel treatment strategies aiming to eliminate or attenuate the invasive phenotype of glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, could offer a profound therapeutic benefit to patients. We previously demonstrated one method to create invasive sub-populations of GBM ...

journal_title：Anticancer research

authors： Koo S,Martin G,Toussaint LG

更新日期：2015-06-01 00:00:00

abstract：:Surgery remains the mainstay of treatment for breast cancer, including complete or partial mastectomy and lumpectomy. Breast reconstruction has gained popularity mainly due to its tremendous impact on the psychological status of the patients. Autologous fat grafting is a well-established method used in cosmetic surger...

journal_title：Anticancer research

authors： Spartalis E,Tsilimigras DI,Charalampoudis P,Karachaliou GS,Moris D,Athanasiou A,Spartalis M,Bolkas V,Dimitroulis D,Nikiteas N

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Human DNA topoisomerase I (topo 1) is an essential nuclear enzyme involved in vital cellular processes and the sole target of antitumor drugs of the camptothecin (CPT) family. The CPT derivative topotecan (Tpt, Hycamtin) is currently used in clinic, its effectiveness varying considerably for different types ...

journal_title：Anticancer research

authors： Devy J,Wargnier R,Pluot M,Nabiev I,Sukhanova A

更新日期：2004-05-01 00:00:00

abstract：:Human leukocyte antigen (HLA)-E and HLA-F are classified as non-classical HLA class Ib antigens. Ectopic HLA-E and HLA-F expression was recently detected in cancer cells; however, the clinical implication of their expression remains unknown. A total of 209 patients with gastric cancer were enrolled in this study. Immu...

journal_title：Anticancer research

authors： Ishigami S,Arigami T,Okumura H,Uchikado Y,Kita Y,Kurahara H,Maemura K,Kijima Y,Ishihara Y,Sasaki K,Uenosono Y,Natsugoe S

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND/AIM:To investigate the outcomes of laparoscopic surgery in colorectal cancer patients with dialysis. PATIENTS AND METHODS:Fourteen dialysis (dialysis group) and 567 non-dialysis (non-dialysis group) patients who underwent laparoscopic and open surgery for colorectal cancer between April 2008 and December 20...

journal_title：Anticancer research

authors： Higashino N,Matsuda T,Hasegawa H,Yamashita K,Sakamoto H,Fujikawa M,Yamamoto M,Kanaji S,Oshikiri T,Nakamura T,Suzuki S,Kakeji Y

更新日期：2020-04-01 00:00:00

abstract：:A number of human tumor cell lines originating in tissues which normally express high levels of P-glycoprotein were examined for the expression of mdr-1 RNA and P-glycoprotein and their sensitivity to doxorubicin and vincristine. There was a wide variation in expression levels and in drug sensitivity among the cell li...

journal_title：Anticancer research

authors： Duensing TD,Slate DL

更新日期：1994-01-01 00:00:00

abstract：AIM:To evaluate factors associated with the selection of first-line bevacizumab plus chemotherapy and clinical response in HER2-negative metastatic breast cancer (MBC) in clinical practice in Spain. PATIENTS AND METHODS:All consecutive adult female patients with HER2-negative MBC who had received first-line bevacizuma...

journal_title：Anticancer research

authors： Manso L,Palomo AG,Pérez Carrión R,Cassinello J,Gallegos Sancho I,Chacón López-Muñiz I,Olier C,Fernández-Aramburo A,Llorca C,González X,Llorente R,Torregrosa D,Álvarez I,Gálve E,Bueno C,Garau I,García MJ,González-Santiag

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The differential diagnosis of well-differentiated tumors of follicular cell origin remains a most problematic task in thyroid pathology. Therefore, various diagnostic/prognostic thyroid markers are currently being studied. The aim of our study was to evaluate the proliferative MIB-1 and topoisomerase II-alph...

journal_title：Anticancer research

authors： Ludvíková M,Holubec L Jr,Ryska A,Topolcan O

更新日期：2005-05-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is one of the few tumour types metastatic to the pancreas. In order to evaluate the outcome following resection of pancreatic metastases of RCC a retrospective review of surgical patients was performed. The initial histopathological staging, disease-free interval, surgical outcome and surviv...

journal_title：Anticancer research

authors： Schauer M,Vogelsang H,Siewert JR

更新日期：2008-01-01 00:00:00