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Endometrial blood flow measured by xenon 133 clearance in women with normal menstrual cycles and dysfunctional uterine bleeding.

Abstract：

:Endometrial blood flow was measured through the menstrual cycle in nonpregnant women (28 studies of 17 women with normal menstrual cycles and 32 studies of 20 women with dysfunctional uterine bleeding) with use of a clearance technique in which 100 to 400 microCi of the gamma-emitting isotope, xenon 133 in saline solution was instilled into the uterine cavity. The mean (+/- SEM) endometrial blood flow in normal cycles was 27.7 +/- 2.6 ml/100 gm/min, with a significant elevation in the middle to late follicular phase, followed by a substantial fall and a secondary slow luteal phase rise that was maintained until the onset of menstruation. There was a significant correlation between plasma estradiol levels and endometrial blood flow in the follicular but not the luteal phase. Blood flow patterns in women with ovulatory dysfunctional bleeding were similar to normal, except for a significantly lower middle follicular rate. Women with anovulatory dysfunctional bleeding exhibited exceedingly variable flow rates.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Fraser IS,McCarron G,Hutton B,Macey D

doi

10.1016/0002-9378(87)90229-8

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

158-66

issue

1

eissn

0002-9378

issn

1097-6868

pii

0002-9378(87)90229-8

journal_volume

156

pub_type

杂志文章

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