The prediction and prevention of intrapartum fetal asphyxia in preterm pregnancies.

Abstract:

OBJECTIVE:This study was undertaken to examine the contribution of electronic fetal heart rate monitoring in the prediction and prevention of intrapartum fetal asphyxia in the preterm pregnancy. STUDY DESIGN:The outcome of 40 pregnancies with biochemically confirmed intrapartum fetal asphyxia (ie, an umbilical artery base deficit >12 mmol/L) was examined. This included 20 pregnancies that were delivered abdominally matched with 20 pregnancies that were delivered vaginally. Antepartum and intrapartum clinical risk factors and newborn complications were documented. The interpretation of the fetal heart rate record as determined by the responsible clinicians was recorded. Fetal asphyxia was classified as mild, moderate, or severe on the basis of an umbilical artery base deficit of >12 mmol/L and newborn encephalopathy and other organ system complications. RESULTS:Fetal asphyxia was classified as mild in 21 pregnancies and as moderate or severe in 19 pregnancies. The fetal heart rate record was predictive of fetal asphyxia in 27 pregnancies and nonpredictive in 11 pregnancies. The predictive fetal heart rate record was the primary indication for intervention in 21 of the 24 pregnancies that were delivered by cesarean delivery in the first stage or operative vaginal delivery in the second stage of labor. Newborn outcome may have been influenced by intervention and delivery because of a predictive fetal heart rate record in 10 pregnancies with mild fetal asphyxia and in 9 pregnancies with moderate or severe fetal asphyxia. CONCLUSION:Electronic fetal monitoring is a useful screening test for the prediction of intrapartum fetal asphyxia in the preterm pregnancy. A predictive fetal heart rate record was the principle indication that led to intervention and delivery. A prediction of fetal asphyxia that leads to intervention and delivery may prevent or modify moderate or severe newborn morbidity as the result of fetal asphyxia.

journal_name

Am J Obstet Gynecol

authors

Low JA,Killen H,Derrick EJ

doi

10.1067/mob.2002.119642

subject

Has Abstract

pub_date

2002-02-01 00:00:00

pages

279-82

issue

2

eissn

0002-9378

issn

1097-6868

pii

S0002937802697856

journal_volume

186

pub_type

杂志文章
  • Group B streptococci during pregnancy: a comparison of two screening and treatment protocols.

    abstract:OBJECTIVE:The objective was to evaluate whether the rate of neonatal group B streptococcal infection could be reduced by screening for group B streptococci during the third trimester of pregnancy. STUDY DESIGN:Two periods in which different screening and treatment protocols were applied were compared. In period A all ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(98)70063-8

    authors: Hafner E,Sterniste W,Rosen A,Schuchter K,Plattner M,Asboth F,Philipp K

    更新日期:1998-09-01 00:00:00

  • Reduced uterine blood flow and fetal hypoxemia with acute maternal stress: experimental observation in the pregnant baboon.

    abstract::The effects of maternal hyperexcitability on the fetus were studied in 17 baboons. In the period of agitation, induced by stressful stimulus such as exposure to bright light or by clamping of the toe, the mother exhibited an increase in arterial blood pressure and, in some instances, arrhythmia. These changes were acc...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(16)33032-0

    authors: Morishima HO,Yeh MN,James LS

    更新日期:1979-06-01 00:00:00

  • Selective termination: clinical experience and residual risks.

    abstract::Assisted reproductive technologies have aided thousands of couples, but complications have resulted in multifetal pregnancies creating a bitter irony for infertility patients. In an effort to increase the rate of intact survival, we have successfully performed transabdominal first-trimester selective termination proce...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)90922-t

    authors: Evans MI,May M,Drugan A,Fletcher JC,Johnson MP,Sokol RJ

    更新日期:1990-06-01 00:00:00

  • Inner thigh taping vs traction for cervical ripening with a Foley catheter: a randomized controlled trial.

    abstract:OBJECTIVE:To assess the effectiveness of inner thigh "Taping" compared with "Traction" using a weighted bag when an intracervical Foley catheter is used for cervical ripening. STUDY DESIGN:We performed a randomized controlled trial at a tertiary hospital on women with a singleton pregnancy in cephalic presentation adm...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ajog.2013.05.028

    authors: Gibson KS,Mercer BM,Louis JM

    更新日期:2013-09-01 00:00:00

  • Chronic fungal vaginitis: the value of cultures.

    abstract:OBJECTIVE:Our purpose was to examine the importance of fungal cultures in evaluating patients with symptoms of chronic vaginitis by assessing the relative contribution of various yeast species and by comparing infections caused by Candida albicans with those caused by other species. STUDY DESIGN:A prospective observat...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(95)90347-x

    authors: Nyirjesy P,Seeney SM,Grody MH,Jordan CA,Buckley HR

    更新日期:1995-09-01 00:00:00

  • Intrapartum hepatitis B screening.

    abstract:OBJECTIVE:The purpose of this study was to determine the prevalence of acute hepatitis B in intrapartum patients and to describe the birth-to-administration interval of the hepatitis B vaccine and immune globulin in hepatitis B surface antigen-positive patients detected by intrapartum screening. STUDY DESIGN:Hepatitis...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(95)90254-6

    authors: Petermann S,Ernest JM

    更新日期:1995-08-01 00:00:00

  • The potential role of prolactin as a modulator of the secretion of proinflammatory mediators in chorioamniotic membranes in term human gestation.

    abstract:OBJECTIVE:To test the effect of prolactin (PRL) on expression of proinflammatory cytokines and matrix metallopeptidase 9 (MMP-9) in vitro. STUDY DESIGN:Tissue explants were incubated from 4 to 48 hours alone or in the presence of 500 ng/mL PRL, and mRNA expression in tissues and secretion of interleukin (IL)-1β, tumor...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2014.01.039

    authors: Zaga-Clavellina V,Parra-Covarrubias A,Ramirez-Peredo J,Vega-Sanchez R,Vadillo-Ortega F

    更新日期:2014-07-01 00:00:00

  • Gap junction currents in cultured muscle cells from human myometrium.

    abstract:OBJECTIVE:The electrophysiologic properties of gap junctions between human myometrial smooth muscle cells were studied. STUDY DESIGN:Double whole-cell patch clamp recordings were made on pairs of cells from primary cultures of myometrial cells from women undergoing cesarean section. Macroscopic gap junction currents w...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(98)70443-0

    authors: Miyoshi H,Boyle MB,MacKay LB,Garfield RE

    更新日期:1998-03-01 00:00:00

  • Prognostic factors and complication rates for cervical cerclage: a review of 482 cases.

    abstract::Charts from 482 singleton pregnancies undergoing cerclage placement in patients over a 6-year period were reviewed. Cervical dilatation at time of surgery, number of previous spontaneous losses, and gestational age at placement were key determinants of outcome. The most frequent complication, premature rupture of the ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(91)90283-w

    authors: Treadwell MC,Bronsteen RA,Bottoms SF

    更新日期:1991-09-01 00:00:00

  • Idiopathic sclerosing peritonitis associated with florid mesothelial hyperplasia, ovarian fibromatosis, and endometriosis: a new disorder of abdominal mass.

    abstract::A 35-year-old woman underwent exploratory laparotomy for ovarian enlargement, massive ascites, and intestinal obstruction. Sclerosing peritonitis associated with florid mesothelial hyperplasia, ovarian fibromatosis, and endometriosis were diagnosed postoperatively. We add to the literature this new association of bila...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(97)70581-7

    authors: Frigerio L,Taccagni GL,Mariani A,Mangili G,Ferrari A

    更新日期:1997-03-01 00:00:00

  • Misoprostol for intrauterine device insertion in nulliparous women: a randomized controlled trial.

    abstract:OBJECTIVE:To examine the effects of preprocedure misoprostol on intrauterine device (IUD) placement in nulliparous women. STUDY DESIGN:In this randomized controlled double-blind trial at the University of New Mexico reproductive health clinic, nulliparous women requesting an IUD were randomized to 400 mcg of buccal mi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ajog.2013.11.018

    authors: Espey E,Singh RH,Leeman L,Ogburn T,Fowler K,Greene H

    更新日期:2014-03-01 00:00:00

  • Identification of a deoxyribonucleic acid allelic variant for beta 1-4 galactosyltransferase expression associated with male sperm binding/penetration infertility.

    abstract::Studies on mouse sperm-egg binding and fertilization have been suggested to involve the interaction of sperm-associated beta 1-4 galactosyltransferase with egg zona pellucida glycoproteins. A population of human males, whose sperm demonstrated an inability to penetrate ovulated zona pellucida-free hamster eggs in vitr...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(89)90180-4

    authors: Humphreys-Beher MG,Blackwell RE

    更新日期:1989-05-01 00:00:00

  • Pregnancy and parturition negatively impact vaginal angle and alter expression of vaginal MMP-9.

    abstract:BACKGROUND:Parity is the greatest risk factor for the development of pelvic organ prolapse. The normally supported vagina is pulled up and back over the levator ani. Loss of vaginal angulation has been associated with prolapse and may represent injury to the vaginal supportive tissues. OBJECTIVE:We proposed and examin...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ajog.2017.11.572

    authors: Oliphant S,Canavan T,Palcsey S,Meyn L,Moalli P

    更新日期:2018-02-01 00:00:00

  • Evaluation and management of complications from synthetic mesh after pelvic reconstructive surgery: a multicenter study.

    abstract:OBJECTIVE:The purpose of this study was to describe the evaluation and management of synthetic mesh-related complications after surgery for stress urinary incontinence (SUI) and/or pelvic organ prolapse (POP). STUDY DESIGN:We conducted a multicenter, retrospective analysis of women who attended 4 US tertiary referral ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ajog.2013.10.012

    authors: Abbott S,Unger CA,Evans JM,Jallad K,Mishra K,Karram MM,Iglesia CB,Rardin CR,Barber MD

    更新日期:2014-02-01 00:00:00

  • The promise of pharmacologic modification of ovum transport in contraceptive development.

    abstract::The mechanisms whereby estradiol retards ovum transport through the rabbit oviduct were investigated. 40 controls were given intravenous injections of 100 units of human chorionic gonadotropin (HCG). (Ovulation follows injection by 10-14 hours.) 24 hours after injection 20 controls were sacrificed; a 90.5% recovery...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(73)91043-0

    authors: Pauerstein CJ,Fremming BD,Hodgson BJ,Martin JE

    更新日期:1973-05-15 00:00:00

  • The correlation of biochemical monitoring versus umbilical flow velocity measurements of the human fetus.

    abstract::The pulsatility index of the fetal umbilical arteries was evaluated in 14 high-risk pregnant patients delivered by cesarean section between 30 and 35 weeks of gestation. Transabdominal cord sampling by ultrasonic guidance was performed on 10 of these patients. Umbilical arterial and venous blood was obtained in all pa...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(88)90418-8

    authors: Ferrazzi E,Pardi G,Bauscaglia M,Marconi AM,Gementi B,Bellotti M,Makowski EL,Battaglia FC

    更新日期:1988-11-01 00:00:00

  • Detecting changes in functional ability in women with premenstrual syndrome.

    abstract::There has been a lack of objective assessment of the disruptive effect that the symptomatology of premenstrual syndrome has on the functional performance of affected women. This study assessed the functional performance of women with premenstrual syndrome at four phases of the menstrual cycle. Twelve women with premen...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(87)90267-5

    authors: Posthuma BW,Bass MJ,Bull SB,Nisker JA

    更新日期:1987-02-01 00:00:00

  • Peritoneal serous papillary carcinoma, a phenotypic variant of familial ovarian cancer: implications for ovarian cancer screening.

    abstract:OBJECTIVE:Our purpose was to report the cancers arising during a familial ovarian cancer screening program and investigate the tumor's clonality and association with BRCA1 and BRCA2 mutations. STUDY DESIGN:Program participants with a diagnosis of ovarian cancer or peritoneal serous papillary carcinoma were identified ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(99)70663-0

    authors: Karlan BY,Baldwin RL,Lopez-Luevanos E,Raffel LJ,Barbuto D,Narod S,Platt LD

    更新日期:1999-04-01 00:00:00

  • The value of amniotic fluid interleukin-6 determination in patients with preterm labor and intact membranes in the detection of microbial invasion of the amniotic cavity.

    abstract:OBJECTIVES:Our purpose was to (1) determine the value of amniotic fluid interleukin-6 determination in the detection of microbial invasion of the amniotic cavity and (2) compare interleukin-6 to other rapid tests in the evaluation of preterm labor. STUDY DESIGN:Amniotic fluid interleukin-6 was determined quantitativel...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0002-9378(94)70057-5

    authors: Coultrip LL,Lien JM,Gomez R,Kapernick P,Khoury A,Grossman JH

    更新日期:1994-10-01 00:00:00

  • Effects of the intrauterine contraceptive device on endometrial enzyme and carbohydrate histochemistry.

    abstract::Endometrial biopsies at varying times in the menstrual cycle were obtained from 30 healthy women (16-41 years) to be used as controls, and 19 women (16-36 years), who wore an IUD (Mazlin spring, Lippes loop, or Birnburg bow) for from 5 months to 4 years, in order to study histological changes in the endometrium in th...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(70)90508-9

    authors: Hester LL Jr,Kellett WW 3rd,Spicer SS,Williamson HO,Pratt-Thomas HR

    更新日期:1970-04-15 00:00:00

  • Cervicoisthmic cerclage: transabdominal vs transvaginal approach.

    abstract:OBJECTIVE:We sought to compare the outcomes of cervicoisthmic (CI) cerclage using traditional transabdominal (TA) approach vs the lesser used transvaginal (TV) approach. STUDY DESIGN:We conducted a retrospective cohort study of women who underwent placement of a CI cerclage. RESULTS:Before CI placement, the abdominal...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2009.03.020

    authors: Witt MU,Joy SD,Clark J,Herring A,Bowes WA,Thorp JM

    更新日期:2009-07-01 00:00:00

  • The impact of the definition of preeclampsia on disease diagnosis and outcomes: a retrospective cohort study.

    abstract:BACKGROUND:The diagnostic criteria for preeclampsia have evolved from the traditional definition of de novo hypertension and proteinuria to a broader definition of hypertension with evidence of end-organ dysfunction. Although this change is endorsed by various societies such as the International Society for the Study o...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2020.08.019

    authors: Reddy M,Fenn S,Rolnik DL,Mol BW,da Silva Costa F,Wallace EM,Palmer KR

    更新日期:2020-08-12 00:00:00

  • Dramatic pyrexic and cardiovascular response to intravaginal prostaglandin E2.

    abstract::The efficacy of prostaglandin E2 (PGE2) for the induction of labor in pregnancies complicated by IUFD or missed abortion has been demonstrated. Gastrointestinal and pyrexic side effects are frequently observed. The following report describes two patients with documented IUFD who experienced a dramatic pyrexic and card...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(78)90793-7

    authors: Phelan JP,Meguiar RV,Matey D,Newman C

    更新日期:1978-09-01 00:00:00

  • Use of laparoscopy to determine the microbiologic etiology of acute salpingitis.

    abstract::To determine the microbiologic etiology of acute salpingitis, laparoscopy was used in 26 patients to obtain specimens for a variety of microorganisms directly from the fallopian tube. Simultaneous culdocentesis was performed to obtain peritoneal fluid for microbiologic analysis. A variety of microorganisms were isolat...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(79)90798-1

    authors: Sweet RL,Mills J,Hadley KW,Blumenstock E,Schachter J,Robbie MO,Draper DL

    更新日期:1979-05-01 00:00:00

  • Fetal evaluation by percutaneous blood sampling.

    abstract::Percutaneous umbilical blood sampling (cordocentesis) provides direct access to the fetal circulation in the second and third trimesters of pregnancy. Seventeen patients underwent this procedure between December 1985 and December 1986 for evaluation of a variety of clinical situations, including nonlethal fetal abnorm...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(88)90795-8

    authors: Hogge WA,Thiagarajah S,Brenbridge AN,Harbert GM

    更新日期:1988-01-01 00:00:00

  • The state of hormonal contraception today: enhancing clinician/patient communications.

    abstract::Women's health nurses and nurse practitioners have a unique opportunity to provide high-quality primary and preventive care and play a critical role in coordinating and delivering effective contraceptive methods. The strategies and techniques that they routinely employ during counseling and education can help improve ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ajog.2011.07.001

    authors: Wysocki S

    更新日期:2011-10-01 00:00:00

  • Epithelial cells from normal human endometrium express a tumor-associated glycoprotein (TAG-72) epitope in vitro.

    abstract::Monoclonal antibody B72.3 identifies a tumor-associated glycoprotein (TAG-72) epitope derived from a human breast carcinoma metastasis. Recently, expression of this epitope was noted in normal endometrium during the secretory, but not proliferative, menstrual interval. In light of known hormonal control of normal endo...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)91179-g

    authors: Osteen KG,Anderson TL,Hargrove JT,Hill GA,Gorstein F

    更新日期:1990-08-01 00:00:00

  • Association of immunoreactive eosinophil major basic protein with placental septa and cysts.

    abstract::A protein that is immunochemically indistinguishable from the major basic protein of the eosinophil granule is present at elevated concentrations in the plasma of pregnant women. Major basic protein has been localized to placental trophoblasts known as X cells. Because X cells are located in placental septa and septal...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(91)90107-3

    authors: Wasmoen TL,Coulam CB,Benirschke K,Gleich GJ

    更新日期:1991-08-01 00:00:00

  • Implementation and evaluation of a training program to improve resident teaching skills.

    abstract:OBJECTIVE:This study was undertaken to develop, implement, and evaluate a program designed to improve residents' teaching skills. STUDY DESIGN:A training program to improve the teaching skills of obstetrics and gynecology residents was developed and implemented. All residents completed a survey of their teaching skill...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/s0002-9378(03)00879-2

    authors: Frattarelli LC,Kasuya R

    更新日期:2003-09-01 00:00:00

  • Modern indications for cesarean section.

    abstract::Total cesarean section rates and rates of various indications for primary cesarean section were reviewed for four yearly periods during the past decade. The time periods studied were chosen to follow the introduction of new obstetric practices and technologic advances in monitoring fetal condition. The total cesarean ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(79)90426-5

    authors: Mann LI,Gallant J

    更新日期:1979-10-15 00:00:00