Abstract:
:Age is a critical determinant of the ability of most arthropod vectors to transmit a range of human pathogens. This is due to the fact that most pathogens require a period of extrinsic incubation in the arthropod host before pathogen transmission can occur. This developmental period for the pathogen often comprises a significant proportion of the expected lifespan of the vector. As such, only a small proportion of the population that is oldest contributes to pathogen transmission. Given this, strategies that target vector age would be expected to obtain the most significant reductions in the capacity of a vector population to transmit disease. The recent identification of biological agents that shorten vector lifespan, such as Wolbachia, entomopathogenic fungi and densoviruses, offer new tools for the control of vector-borne diseases. Evaluation of the efficacy of these strategies under field conditions will be possible due to recent advances in insect age-grading techniques. Implementation of all of these strategies will require extensive field evaluation and consideration of the selective pressures that reductions in vector longevity may induce on both vector and pathogen.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Cook PE,McMeniman CJ,O'Neill SLdoi
10.1007/978-0-387-78225-6_11subject
Has Abstractpub_date
2008-01-01 00:00:00pages
126-40eissn
0065-2598issn
2214-8019journal_volume
627pub_type
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