Modifying insect population age structure to control vector-borne disease.

Abstract:

:Age is a critical determinant of the ability of most arthropod vectors to transmit a range of human pathogens. This is due to the fact that most pathogens require a period of extrinsic incubation in the arthropod host before pathogen transmission can occur. This developmental period for the pathogen often comprises a significant proportion of the expected lifespan of the vector. As such, only a small proportion of the population that is oldest contributes to pathogen transmission. Given this, strategies that target vector age would be expected to obtain the most significant reductions in the capacity of a vector population to transmit disease. The recent identification of biological agents that shorten vector lifespan, such as Wolbachia, entomopathogenic fungi and densoviruses, offer new tools for the control of vector-borne diseases. Evaluation of the efficacy of these strategies under field conditions will be possible due to recent advances in insect age-grading techniques. Implementation of all of these strategies will require extensive field evaluation and consideration of the selective pressures that reductions in vector longevity may induce on both vector and pathogen.

journal_name

Adv Exp Med Biol

authors

Cook PE,McMeniman CJ,O'Neill SL

doi

10.1007/978-0-387-78225-6_11

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

126-40

eissn

0065-2598

issn

2214-8019

journal_volume

627

pub_type

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