Abstract:
:An iterative scheme of short-term bacterial mutagenesis assays and multidimensional liquid chromatographic methods was used to isolate mutagens from a neutral fraction of a complex carcinogenic tar formed as a by-product of coal gasification. Mutagens in the complementary reversed- and normal-phase liquid chromatographic fractions were identified by capillary column gas chromatography and gas chromatography-mass spectrometry. The principal mutagens included a variety of 4- to 6-ring unsubstituted polycyclic aromatic hydrocarbons, their alkylated homologs, and related methylene-bridged compounds. Most of the unsubstituted mutagens were known carcinogens that were qualitatively similar to those detected by carcinogenicity assays of fractions from other types of coal tars and cigarette smoke condensate. The chromatographic approach is generally applicable to complex mixtures and is especially well suited for fractionating mixtures of aromatic compounds and their alkyl homologs.
journal_name
Environ Resjournal_title
Environmental researchauthors
Haugen DA,Stamoudis VCdoi
10.1016/s0013-9351(86)80135-9subject
Has Abstractpub_date
1986-12-01 00:00:00pages
400-19issue
2eissn
0013-9351issn
1096-0953pii
S0013-9351(86)80135-9journal_volume
41pub_type
杂志文章abstract::The effects of cadmium on the immune system have been extensively studied, although relatively little is known about the nature of the interaction between cadmium and lymphocytes. We describe studies that examine the uptake and subcellular distribution of cadmium in resting and mitogen-activated mouse splenic lymphocy...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(89)80071-4
更新日期:1989-08-01 00:00:00
abstract:BACKGROUND:Associations between perfluoroalkyl acids (PFASs) and human thyroid hormone levels remain unclear, especially during early pregnancy when small changes in maternal thyroid hormones can affect fetal brain development. OBJECTIVES:To examine associations between maternal serum PFAS levels and maternal thyroid ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.06.012
更新日期:2014-08-01 00:00:00
abstract::Environmental exposures and poor sleep outcomes are known to have consequential effects on human health. This integrative review first seeks to present and synthesize existing literature investigating the relationship between exposure to various environmental factors and sleep health. We then present potential mechani...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1016/j.envres.2020.110406
更新日期:2020-10-29 00:00:00
abstract::We conducted a study in Egypt to assess the determinants of organochlorine serum levels among premenopausal women and the risk of premenopausal breast cancer for women with high organochlorine serum levels. We included 69 breast cancer patients and 53 controls consisting of visitors to the hospitals of the cancer pati...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(02)00056-7
更新日期:2003-06-01 00:00:00
abstract::Fullerenes are carbon nanomaterials that have awaken a strong interest due to their adsorption properties and potential applications in many fields. However, there are some gaps of information about their effects and bioconcentration potential in the aquatic biota. In the present work, freshwater biofilms and snails (...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108715
更新日期:2020-01-01 00:00:00
abstract::The in vitro genotoxic and the soft-agar anchorage independent cell transformation ability of titanium dioxide nanoparticles (nano-TiO2) and its microparticulated form has been evaluated in human embryonic kidney (HEK293) and in mouse embryonic fibroblast (NIH/3T3) cells. Nano-TiO2 of two different sizes (21 and 50 nm...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.10.032
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Age at female puberty is associated with adult morbidities, including breast cancer and diabetes. Hormonally active chemicals are suspected of altering pubertal timing. We examined whether persistent organic pollutants (POPs) are associated with age at menarche in a longitudinal study. METHODS:We analyzed d...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108551
更新日期:2019-09-01 00:00:00
abstract::Seasonal patterns of birth outcomes, such as low birth weight, preterm birth and stillbirth, have been found around the world. As a result, there has been an increasing interest in evaluating short-term exposure to ambient temperature as a determinant of adverse birth outcomes. This paper reviews the epidemiological e...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1016/j.envres.2011.01.023
更新日期:2011-04-01 00:00:00
abstract::Recent studies from the Madre de Dios region of Peru report elevated mercury exposure among the general population. Our objective was to assess mercury exposure, risk factors, risk perceptions, and knowledge among women of childbearing age, a population of concern due to risks to infant and fetal health. We collected ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108786
更新日期:2019-12-01 00:00:00
abstract::The human biomonitoring (HBM) of metals is a part of the ongoing project SPoTT for the longitudinal health surveillance of the population living near a waste-to-energy (WTE) incinerator (Turin, Italy). The HBM of metals in the SPoTT population aimed to evaluate: i) reference values (RVs) before the WTE incinerator sta...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.04.013
更新日期:2016-07-01 00:00:00
abstract::The pleural and peritoneal mesothelium is a major target in asbestos exposure where mesothelial cell proliferation, exfoliation, and neoplasia have been reported in workers and experimental animals. The objective of this study was to determine the role of pleural leukocytes in mesothelial cell damage caused by asbesto...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1994.1014
更新日期:1994-02-01 00:00:00
abstract::Antipyrine (ANT), as a widely used relieve headache, fever anti-inflammatory pharmaceutical in medical treatment, is difficult to be removed completely in water. The application of photocatalytic removal of ANT is restricted to UV light irradiation (<5% of solar energy), and the degradation pathways of ANT require mor...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109468
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:There is growing evidence that persistent organic pollutants (POPs) may play an important role in increasing the risk of gestational diabetes mellitus (GDM). OBJECTIVES:The aim of this study was to examine the association between polychlorinated biphenyls (PCBs, 10 congeners) and polybrominated diphenyl eth...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.09.002
更新日期:2016-11-01 00:00:00
abstract::The aim of this study was to assess the odor immission derived from full-scale composting of different abundant and highly pollutant organic waste: sewage sludge with bulking agent (SL), sewage sludge pretreated through anaerobic digestion and supplemented with bulking agent (SL-AD), and market waste with olive leaves...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.09.001
更新日期:2018-11-01 00:00:00
abstract::Polychorinated biphenyl (PCB) congeners are a cause for concern due to their persistence in the environment, their lipophilic properties that cause them to bio-accumulate in top predators, and their adverse effects on mammalian health. For example, the common urogenital carcinoma reported in California sea lions (Zalo...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.08.028
更新日期:2018-11-01 00:00:00
abstract::Humans exposed to methylmercury (MeHg) can suffer from adverse health impacts, e.g., serious neurological damage; however, fish is also a good source of omega-3 fish oils which promotes infants' neurological development. Because eating fish is the primary mechanism of MeHg exposure, federal and state agencies issue fi...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2013.08.012
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of short-term exposure to air pollutants on inflammation-sensitive biomarkers in apparently healthy individuals. METHODS:We enrolled all participants from The Tel-Aviv Sourasky Medical Center inflammation survey held between 2003 and 2006, excluding participants with an acute or chron...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2007.08.006
更新日期:2008-01-01 00:00:00
abstract::The role of humic acids in the transport of trace elements in the Sava river biocycle (near Zagreb, Yugloslavia) has been investigated by means of neutron activation analysis. Humic acids can accumulate certain trace elements, but little is known about their selectivity under certain physicochemical conditions. Humic ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(86)80052-4
更新日期:1986-04-01 00:00:00
abstract:BACKGROUND:Epidemiological evidence regarding the relationship between maternal secondhand smoke (SHS) exposure during pregnancy and postnatal SHS exposure and childhood behavioral problems is scarce. OBJECTIVE:The present prebirth cohort study investigated the association between perinatal smoking exposure and behavi...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.08.010
更新日期:2016-11-01 00:00:00
abstract::Evapotranspiration (ET) is a central process in the climate system that plays a crucial role in the regional water cycle and climate regulation. However, estimating the effects of regional ET on the regional water cycle and climate regulation remains challenging due to the lack of quantitative methods and large-scale ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110200
更新日期:2020-12-01 00:00:00
abstract::Minamata disease is methylmercury poisoning from consuming fish and shellfish contaminated by industrial waste. The polluted seafood was widely consumed in the area around Minamata, but many individuals were never examined for or classified as having Minamata disease. Following the determination of the Supreme Court o...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2007.05.012
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Allergic sensitization during childhood is a dynamic process with a substantial rate of remission. Factors influencing this process are largely unknown. METHODS:We conducted a two-year prospective study among 121 schoolchildren (mean age, 5.8 years; 64 boys). We measured urea, club cell protein (CC16), β2-m...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.06.009
更新日期:2017-10-01 00:00:00
abstract::Biochemical alterations in guinea pig lungs caused by hematite dust were followed at 150 days after intratracheal administration of the dust. In vivo dust exposure caused a significant increase in mitochondrial protein content and cytochrome c oxidase activity whereas diaphorase activity remained unaltered. Mitochondr...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(83)90119-6
更新日期:1983-12-01 00:00:00
abstract::Iron-modified graphitic carbon nitride (FG materials) was prepared through a simple and cost-effective method using iron oxide and melamine to achieve simultaneous oxidation and adsorption of arsenic. We hypothesized that graphitic carbon nitride oxidizes As(III) to As(V) under light irradiation, and the converted As(...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109832
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Given the lack of research on the personal exposure to fine particles (PM2.5) in Hong Kong, we examined the association between short-term personal exposure to PM2.5 and their constituents and inflammation in exhaled breath in a sample of healthy adult residents. METHOD:Forty-six participants underwent pers...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.02.009
更新日期:2018-07-01 00:00:00
abstract::Inhalation of welding fume (WF) can result in the deposition of toxic metals, such as manganese (Mn), in the brain and may cause neurological changes in exposed workers. Alterations in telomere length are indicative of cellular aging and, possibly, neurodegeneration. Here, we investigated the effect of WF inhalation o...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108900
更新日期:2020-01-01 00:00:00
abstract::Minamata disease is methyl mercury intoxication from fish contaminated by a chemical factory in Minamata city. Based on the results of our regional survey, cardinal clinical features of the disease were clarified by a multivariant analysis of all symptoms in inhabitants in the polluted area. The clinical features were...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1006/enrs.1993.1137
更新日期:1993-10-01 00:00:00
abstract::The intake of food cadmium (Cd) in microg/day over time can increase the body burden of this element. Some human populations that consume subsistence rice-based diets low in calcium (Ca), iron (Fe), and zinc (Zn) are more susceptible to Cd poisoning than populations that consume more nutritious diets. This study deter...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.2000.4236
更新日期:2001-03-01 00:00:00
abstract::Elevated exposure to arsenic disproportionately affects populations relying on private well water in the United States (US). This includes many American Indian (AI) communities where naturally occurring arsenic is often above 10 µg/L, the current US Environmental Protection Agency safety standard. The Strong Heart Wat...
journal_title:Environmental research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.envres.2018.09.016
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Epidemiological studies suggest strong association of lung disorders with occupational exposure to asbestos, silicon and arsenic. The chronic occupational exposure primarily through inhalation results in adverse outcome on the respiratory tract which may also be fatal. Although several mechanisms have attrib...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1016/j.envres.2016.02.038
更新日期:2016-05-01 00:00:00